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1. 发明申请

WO2010035183A2 PATIENT SPECIFIC ANATOMICAL SKETCHES FOR MEDICAL REPORTS 审中-公开
标题翻译：患者特殊解剖医学报告草图
公开(公告)号：WO2010035183A2
公开(公告)日：2010-04-01
申请号：PCT/IB2009/054070
申请日：2009-09-17
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , LORENZ, Cristian , DRIES, Sebastian, P., M. , RENISCH, Steffen , VON BERG, Jens
发明人： LORENZ, Cristian , DRIES, Sebastian, P., M. , RENISCH, Steffen , VON BERG, Jens
IPC分类号： G06T17/00
CPC分类号： G06F19/3487 , G06F19/00 , G06F19/321 , G06T7/0012 , G06T7/12 , G06T7/149 , G06T19/20 , G06T2207/10072 , G06T2207/10116 , G06T2207/30012 , G06T2219/2021 , G16H15/00
摘要： The invention relates to a system (100) for producing a representation of an object in image data, based on a template coupled to a model of the object, the system comprising a model unit for adapting the model to the object in the image data, and a template unit for adapting the template to the adapted model on the basis of the coupling between the template and the model. The template defines a representation of the object which is simpler to interpret than the model. The template may be arranged to emphasize useful features of the object. The template comprises substantially fewer degrees of freedom and thus can be efficiently adapted to the model. Because the template of the invention is coupled to the model, the position, orientation and/or shape of the template is determined by the model adapted to the object in the image data. Hence, the template is adapted to the image data. The adapted template is capable of representing the object and its individual characteristics, e.g., the shape of the object as well as the position and/or orientation of the object with respect to an external reference system defined, e.g., based on the image data.
摘要翻译：本发明涉及一种用于基于耦合到对象模型的模板来产生图像数据中的对象的表示的系统（100），该系统包括用于使模型适应图像数据中的对象的模型单元，以及模板单元，用于基于模板和模型之间的耦合来将模板适配到适配模型。模板定义了比模型更简单的对象的表示。模板可以被布置为强调对象的有用特征。该模板包括基本上更少的自由度，因此可以有效地适应于该模型。因为本发明的模板耦合到模型，所以模板的位置，取向和/或形状由适于图像数据中的对象的模型确定。因此，该模板适合图像数据。适应的模板能够表示对象及其各自的特征，例如对象的形状以及对象相对于例如基于图像数据定义的外部参考系统的位置和/或取向。

2. 发明申请

WO2010029470A1 SYSTEM AND METHOD FOR PROCESSING MEDICAL IMAGES 审中-公开
标题翻译：用于处理医学图像的系统和方法
公开(公告)号：WO2010029470A1
公开(公告)日：2010-03-18
申请号：PCT/IB2009/053837
申请日：2009-09-03
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , DRIES, Sebastian, P., M. , LORENZ, Cristian
发明人： DRIES, Sebastian, P., M. , LORENZ, Cristian
IPC分类号： G06F19/00
CPC分类号： G06F19/321 , G06F19/00 , G06T7/38 , G06T2207/30004
摘要： The invention provides a system, e.g. a Picture Archiving and Communications System (PACS), and a method for identifying the presence of relevant medical images, e.g. medical images ofthe same region of interest or anatomical feature(s) of the same patient, taken at a different time or by a different acquisition modality. The system ofthe invention notifies a user on the presence of any such relevant image, and is arranged for presenting such relevant images on a display. Two or more medical images may be displayed at the same time or one after the other, overlaid, by sliding a space or time axis, etc. The medical images are scaled and orientated so as to maximize the visual correlation between them, i.e. to make them exhibit the anatomy the most possible alike, so as to ease comparison between anatomical features without disturbing diagnostically relevant contrasts on the medical images.
摘要翻译：本发明提供了一种系统，例如图像存档和通信系统（PACS），以及用于识别相关医学图像的存在的方法，例如，相同患者的相同区域或解剖特征的医学图像在不同的时间或不同的采集模式下进行。本发明的系统通知用户存在任何这样的相关图像，并被布置为在显示器上呈现这样的相关图像。可以通过滑动空间或时间轴等来同时或一个接一个地显示两个或更多个医学图像。医学图像被缩放和定向以使它们之间的视觉相关性最大化，即，使他们展现出最可能的解剖学，以便简化解剖特征之间的比较，而不会扰乱医学图像上的诊断相关的对比度。

3. 发明申请

WO2008065585A3 IMPROVED PATIENT DATA RECORD AND USER INTERFACE 审中-公开
公开(公告)号：WO2008065585A3
公开(公告)日：2008-06-05
申请号：PCT/IB2007/054740
申请日：2007-11-22
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , LORENZ, Cristian , BARSCHDORF, Hans , VON BERG, Jens , BLAFFERT, Thomas , DRIES, Sebastian, P., M. , KABUS, Sven
发明人： LORENZ, Cristian , BARSCHDORF, Hans , VON BERG, Jens , BLAFFERT, Thomas , DRIES, Sebastian, P., M. , KABUS, Sven
IPC分类号： G06F19/00
摘要： A patient data record is described comprising a mean model representative of the patient and further comprises at least one shape model to represent data concerning the patient, in which the said mean model comprises at least one region and the said shape model comprises at least one sub-section, and in which the at least one sub-section of the shape model is linked to the equivalent region of the mean model. This has the advantage of allowing greater structure to the patient record. Further a system is described to present patient data upon queries generated by a user and arranged to access the claimed patient data record, and which is further arranged to provide access to information in the sub-section of the shape model when a query generated by the user accesses the equivalent region of the mean model. This system allows full use of the improved patient data record.

4. 发明申请

WO2009101560A2 APPARATUS FOR SEGMENTING AN OBJECT COMPRISING SUB-OBJECTS 审中-公开
标题翻译：用于分配包含子对象的对象的设备
公开(公告)号：WO2009101560A2
公开(公告)日：2009-08-20
申请号：PCT/IB2009/050495
申请日：2009-02-06
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , BLAFFERT, Thomas , BARSCHDORF, Hans , VON BERG, Jens , DRIES, Sebastian, P., M. , LORENZ, Cristian , WIEMKER, Rafael , KLINDER, Tobias , FRANZ, Astrid, R. , RENISCH, Steffen
发明人： BLAFFERT, Thomas , BARSCHDORF, Hans , VON BERG, Jens , DRIES, Sebastian, P., M. , LORENZ, Cristian , WIEMKER, Rafael , KLINDER, Tobias , FRANZ, Astrid, R. , RENISCH, Steffen
IPC分类号： G06T7/00 , A61B5/00
CPC分类号： G06T5/003 , G06T7/11 , G06T7/149 , G06T2207/10081 , G06T2207/20041 , G06T2207/20081 , G06T2207/20124 , G06T2207/20192 , G06T2207/30061
摘要： The present invention relates to an apparatus (1) for segmenting an object comprising sub-objects shown in an object image. The apparatus comprises a feature image generation unit (2) for generating a feature image showing features related to intermediate regions between the sub-objects and a segmentation unit (3) for segmenting the sub-objects by using the object image and the feature image. Preferentially, the feature image generation unit (2) is adapted for generating a feature image from the object image. In a further embodiment, the feature image generation unit (2) comprises a feature enhancing unit for enhancing features related to intermediate regions between the sub-objects in the object image.
摘要翻译：本发明涉及一种用于分割包含物体图像中所示的子对象的物体的装置（1）。该装置包括：特征图像生成单元，用于生成显示与子对象之间的中间区域相关的特征的特征图像和用于通过使用对象图像和特征图像来分割子对象的分割单元（3）。优选地，特征图像生成单元（2）适于从对象图像生成特征图像。在另一实施例中，特征图像生成单元（2）包括特征增强单元，用于增强与对象图像中的子对象之间的中间区域相关的特征。

5. 发明申请

WO2008065590A1 IMPROVED SEGMENTATION 审中-公开
标题翻译：改进分类
公开(公告)号：WO2008065590A1
公开(公告)日：2008-06-05
申请号：PCT/IB2007/054751
申请日：2007-11-22
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , LORENZ, Cristian , BARSCHDORF, Hans , VON BERG, Jens , BLAFFERT, Thomas , DRIES, Sebastian, P., M , KABUS, Sven
发明人： LORENZ, Cristian , BARSCHDORF, Hans , VON BERG, Jens , BLAFFERT, Thomas , DRIES, Sebastian, P., M , KABUS, Sven
IPC分类号： G06T5/00
CPC分类号： G06T7/149 , G06T7/11 , G06T2207/10072 , G06T2207/30048
摘要： A computer program product is described to adapt a shape model to a patient data set, the data set representing at least a region of anatomy of the patient, and in which the shape model is pre-adapted to a data set representing substantially the same anatomy of the same patient. This provides a surprisingly better segmentation of the data in the data set. In addition, A computer program product is described for the comparison of quantitative patient data and arranged to access quantitative patient data contained in a patient data record, characterized in that the quantitative patient data is in the form of an adapted shape model, adapted from a pre-adapted shape model. This extends the improvement derived by use of pre-adapted shape models and extends them to the use of pre-adapted shape models for data comparison.
摘要翻译：描述了计算机程序产品以将形状模型适应于患者数据集，所述数据集表示至少一个患者的解剖结构的区域，并且其中形状模型预先适应于表示基本上相同的解剖结构的数据集的同一病人。这为数据集中的数据提供了令人惊奇的更好的分割。另外，计算机程序产品被描述为用于比较定量患者数据并被安排用于访问包含在患者数据记录中的定量患者数据，其特征在于定量患者数据是适应形状模型的形式，预适应形状模型。这扩展了通过使用预先调整的形状模型得到的改进，并将其扩展到使用预先调整的形状模型进行数据比较。

6. 发明申请

WO2012153219A1 MOTION COMPENSATED IMAGING 审中-公开
标题翻译：运动补偿成像
公开(公告)号：WO2012153219A1
公开(公告)日：2012-11-15
申请号：PCT/IB2012/052075
申请日：2012-04-26
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , HANSIS, Eberhard Sebastian , LORENZ, Cristian , KLINDER, Tobias , KABUS, Sven , SONG, Xiyun
发明人： HANSIS, Eberhard Sebastian , LORENZ, Cristian , KLINDER, Tobias , KABUS, Sven , SONG, Xiyun
IPC分类号： A61B6/00 , A61B6/03 , G06T11/00
CPC分类号： G06T11/003 , A61B6/032 , A61B6/037 , A61B6/4417 , A61B6/486 , A61B6/5205 , A61B6/5235 , A61B6/5264 , A61B6/5288 , G06T7/0012 , G06T11/005 , G06T2211/412
摘要： A method includes performing a motion compensated reconstruction of functional projection data using a patient-adapted motion model, which is generated based on a generic anatomical motion model and imaging data from a structural scan. A system includes a first adapter (202) configured to adapt a generic anatomical model to structural image data, producing an adapted model, a forward projector (204) configured to forward project the adapted model, producing forward projected data, and a second adapter (206) configured to adapt the forward projected data to individual projections of projected data, which is used to generate the structural image data, producing a patient-adapted motion model.
摘要翻译：一种方法包括使用基于通用解剖运动模型和来自结构扫描的成像数据生成的患者适应运动模型来执行功能投影数据的运动补偿重建。一种系统包括：第一适配器（202），其被配置为使通用解剖模型适应于结构图像数据，产生适应模型;前投影仪（204），被配置为向所述适配模型进行投影，产生向前投影数据;以及第二适配器 206），其被配置为使所述向前投影的数据适应于用于生成所述结构图像数据的投影数据的各个投影，产生患者适应的运动模型。

7. 发明申请

WO2009122338A1 SIMULTANEOUS MODEL-BASED SEGMENTATION OF OBJECTS SATISFYING PRE-DEFINED SPATIAL RELATIONSHIPS 审中-公开
标题翻译：满足预先确定的空间关系的物体同步模型分类
公开(公告)号：WO2009122338A1
公开(公告)日：2009-10-08
申请号：PCT/IB2009/051302
申请日：2009-03-30
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , FRANZ, Astrid, R. , KLINDER, Tobias , WOLZ, Robin, M., B. , LORENZ, Cristian
发明人： FRANZ, Astrid, R. , KLINDER, Tobias , WOLZ, Robin, M., B. , LORENZ, Cristian
IPC分类号： G06T7/00
CPC分类号： G06T7/12 , G06T7/149 , G06T2207/10072 , G06T2207/30012
摘要： The invention relates to a system (100) for segmenting a plurality of objects in image data using simultaneous model-based image segmentation. A surface mesh is adapted to each object to be segmented. To avoid or reduce the possibility of mesh collision,a plurality of connecting edges for connecting two proximal meshes are used. A connection energy defined for the plurality of connecting edges allows controlling the spatial relationship between the first and second mesh. This is achieved by including in the connection energy expression terms that will increase the connection energy when the lengths of edges of the plurality of connecting edges connecting the first and second mesh decrease. Using the reference configuration of the plurality of connecting edges defined based on the pre- positioned first and second mesh allows taking into account prior knowledge about a typical spatial relationship between the first and second object of the plurality of objects.
摘要翻译：本发明涉及一种用于使用同时基于模型的图像分割来分割图像数据中的多个对象的系统（100）。表面网格适合于要分割的每个对象。为了避免或减少网格碰撞的可能性，使用用于连接两个近侧网格的多个连接边缘。为多个连接边限定的连接能量允许控制第一和第二网格之间的空间关系。这是通过在连接第一和第二网格的多个连接边缘的边缘的长度减小的连接能量表达术语中包括将增加连接能量来实现的。使用基于预定义的第一和第二网格定义的多个连接边缘的参考构造允许考虑到关于多个对象中的第一和第二对象之间的典型空间关系的先前知识。

8. 发明申请

WO2009063363A2 COMPUTER-AIDED DETECTION (CAD) OF A DISEASE 审中-公开
标题翻译：一种疾病的计算机辅助检测（CAD）
公开(公告)号：WO2009063363A2
公开(公告)日：2009-05-22
申请号：PCT/IB2008/054632
申请日：2008-11-06
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , LORENZ, Cristian , VON BERG, Jens , BUELOW, Thomas , WIEMKER, Rafael
发明人： LORENZ, Cristian , VON BERG, Jens , BUELOW, Thomas , WIEMKER, Rafael
IPC分类号： G06T7/00
CPC分类号： G06T7/0012 , G06T7/11 , G06T2200/24 , G06T2207/10072 , G06T2207/30061
摘要： The present invention relates to a method for performing computer-aided detection (CAD) of a disease, e.g. lung tumours, on a medical image data set (20) from a imaging modality, such as MRI or CT. Initially, there is perform a segmentation of the medical image data set (20) using an anatomical model. Secondly, the segmented data is analyzed for characteristics of the disease resulting in a set of analysis data (25), and finally the set of analysis data (25) is evaluating with respect to the disease. At least one of these steps comprises as an input a position dependent probability (P_r) for the disease. The invention isadvantageous in that more efficient computations can be performed because the degree ofanalysis in a certain region of the part of the patient, e.g. the lung, can be adjusted or tailored to the level of probability of the disease in the that region. It is thereby possible to increase computational speed and thereby diseases like cancer, in particular cancer nodules in the lungs, can be more effectively found from medical image analysis.
摘要翻译：用于执行疾病的计算机辅助检测（CAD）的方法技术领域本发明涉及用于执行疾病的计算机辅助检测（CAD）的方法。（例如MRI或CT）的医学图像数据组（20）上的肺肿瘤。最初，使用解剖模型执行医学图像数据集（20）的分割。其次，对分段数据进行分析，以获得一组分析数据（25），最后分析数据集（25）针对该疾病进行评估。这些步骤中的至少一个包括疾病的位置依赖概率（P_r）作为输入。本发明的有利之处在于可以进行更有效的计算，因为患者部分的某个区域的分析程度，例如，肺，可以调整或适应该地区疾病的概率水平。因此可以提高计算速度，从而可以从医学图像分析中更加有效地发现诸如癌症的疾病，特别是肺部的癌症结节。

9. 发明申请

WO2006067719A3 A METHOD, A SYSTEM AND A COMPUTER PROGRAM FOR INTEGRATION OF MEDICAL DIAGNOSTIC INFORMATION AND A GEOMETRIC MODEL OF A MOVABLE BODY 审中-公开
公开(公告)号：WO2006067719A3
公开(公告)日：2006-06-29
申请号：PCT/IB2005/054289
申请日：2005-12-16
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , SENEGAS, Julien , LORENZ, Cristian , NETSCH, Thomas , LUND, Heiner, G., K. , STORK, Alexander
发明人： SENEGAS, Julien , LORENZ, Cristian , NETSCH, Thomas , LUND, Heiner, G., K. , STORK, Alexander
IPC分类号： G06T17/40
摘要： The system (10) comprises an input (2) for accessing the suitable input data. The core of the system (10) is formed by a processor (4) which is arranged to operate the components of the system (10), it being the input (2), a computing unit (5), a working memory (6). The computing unit (5) preferably comprises a suitable number of executable subroutines (5a, 5b, 5c, 5d, 5e, and 5f) to enable a constructing of a geometric model of the movable body based on the results of the segmentation step, finding a spatial correspondence between the first and second image dataset, mapping the texture image dataset on geometric model, fusing the geometric model and the mapped texture image dataset. The apparatus (10) according to the invention further comprises a coder (7) arranged to code the determined region of interest in accordance to a pre-selected criterion. The criterion may be selectable from a list of valid criteria, stored in a file (7a). Preferably, the coder (7), the computing unit (5) and the processor (4) are operable by a computer program (3), preferably stored in memory (8). An output (9) is used for outputting the results of the processing, like fused image data representing the textured, preferably animated geometric model of the movable body. The invention further relates to a method for integration of medical diagnostic information and a geometric model of a movable body and to a computer program.

10. 发明申请

WO2008120177A2 PROGRESSIVE MODEL-BASED ADAPTATION 审中-公开
标题翻译：基于模式的适应性
公开(公告)号：WO2008120177A2
公开(公告)日：2008-10-09
申请号：PCT/IB2008/051631
申请日：2008-04-28
申请人： KONINKLIJKE PHILIPS ELECTRONICS N.V. , PHILIPS INTELLECTUAL PROPERTY & STANDARDS GMBH , PETERS, Jochen , ECABERT, Olivier , SCHRAMM, Hauke , WEESE, Juergen , BERG, Jens Von , LORENZ, Cristian
发明人： PETERS, Jochen , ECABERT, Olivier , SCHRAMM, Hauke , WEESE, Juergen , BERG, Jens Von , LORENZ, Cristian
IPC分类号： G06T7/00
CPC分类号： G06T7/149 , G06T7/12 , G06T2207/10072 , G06T2207/30048 , G06T2207/30101
摘要： The invention relates to an adaptation system for adapting a deformable model to an object of interest in an image data set, the system comprising a propagator for propagating a set of predetermined transformation parameters to the model segments that have not yet been activated for adaptation to the image; an activator for activating at least one model segment from the model segments that have not yet been activated for adaptation to the image; and an adapter for adapting the deformable model by optimizing model energy of the deformable model, said model energy comprising internal energy of the plurality of model segments and external energy of at least the latest activated model segment(s). By enabling propagation of the transformation parameters from the model segments that have been adapted to the image to the model segments that have not been adapted to the image, this invention can improve the robustness and flexibility of the adaptation.
摘要翻译：本发明涉及一种用于将可变形模型适应于图像数据集中的感兴趣对象的自适应系统，该系统包括传播器，用于将一组预定变换参数传播到尚未被激活以适应于图片; 用于激活来自尚未被激活用于适应图像的模型段的至少一个模型段的激活器; 以及用于通过优化所述可变形模型的模型能量来适配所述可变形模型的适配器，所述模型能量包括所述多个模型段的内部能量和至少最近激活的模型段的外部能量。通过使来自已经适应于图像的模型段的变换参数能够传播到尚未适应于图像的模型段，本发明可以提高适应性的鲁棒性和灵活性。

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