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    • 1. 发明申请
    • MEANS AND METHOD FOR SENSING A MAGNETIC STRAY FIELD IN BIOSENSORS
    • 用于感应生物传感器中磁场的方法和方法
    • WO2006059270A2
    • 2006-06-08
    • PCT/IB2005/053935
    • 2005-11-28
    • KONINKLIJKE PHILIPS ELECTRONICS N.V.KAHLMAN, Josephus, A., H., M.DE BOER, Bart, M.
    • KAHLMAN, Josephus, A., H., M.DE BOER, Bart, M.
    • H03K19/007
    • G01R33/093B82Y25/00G01R33/1269
    • A magnetic sensor (MS) comprising a magneto-resistive element (GMR) for sensing a magnetic stray field (SF) generated by a magnetizable object (SPB) when magnetized and for generating an electrical object signal (UOB) which depends on the sensed magnetic stray field (SF), the sensor (MS) comprising a magnetic field generator (WR1, WR2) for generating a magnetic field (H, Hext) having a first frequency ((D1) for magnetizing the magnetizable object (SPB), a current source (AC2) for at least generating an AC-current (I2sincθ2t) having a second frequency (o^t) through the magneto-resistive element (GMR), and electronic means for generating an electrical output signal (U0) derived from the electrical object signal (UOB), the electronic means comprising stabilization means for stabilizing the amplitude of the electrical output signal (U0), the stabilization means deriving its information which is needed for said stabilization from the amplitude of a signal component, which is present in the object signal (UOB) during operation, which is linearly dependent on the steepness of the magneto-resistive element (GMR), the steepness being defined as the derivative of the resistance of the magneto-resistive element (GMR) as a function of the magnetic field through the magneto-resistive element in a magnetically sensitive direction of the magneto-resistive element (GMR).
    • 一种磁传感器(MS),包括用于感测由可磁化物体(SPB)产生的磁性杂散磁场(SFB)的磁阻元件(GMR),该磁性磁体元件被磁化并且用于产生取决于感测磁性的电对象信号(UOB) 杂散场(SF),包括用于产生具有第一频率(用于磁化可磁化物体(SPB)的(D1))的磁场(H,Hext)的磁场发生器(WR1,WR2)的传感器(MS) 用于至少通过磁阻元件(GMR)产生具有第二频率(o ^ t)的AC电流(I2sinc2t)的源极(AC2),以及用于产生从 所述电子对象信号(UOB),所述电子装置包括用于稳定所述电输出信号(U0)的振幅的稳定装置,所述稳定装置从存在的信号分量的振幅导出所述稳定所需的信息 在里面 对象信号(UOB),其在线性上取决于磁阻元件(GMR)的陡度,陡度被定义为磁阻元件(GMR)的电阻的导数作为磁性的函数 在磁阻元件(GMR)的磁敏感方向通过磁阻元件。
    • 2. 发明申请
    • A METHOD FOR CALIBRATING A TRANSFER FUNCTION OF A MAGNETIC SENSOR
    • 一种用于校准磁传感器传递函数的方法
    • WO2006059268A2
    • 2006-06-08
    • PCT/IB2005/053930
    • 2005-11-28
    • KONINKLIJKE PHILIPS ELECTRONICS N.V.KAHLMAN, Josephus, A., H., M.DE BOER, Bart, M.
    • KAHLMAN, Josephus, A., H., M.DE BOER, Bart, M.
    • G01N27/72
    • G01R33/093B82Y25/00G01R33/1269
    • A method for calibrating a transfer function of a magnetic sensor (MS) on a substrate (SBSTR) in which sensor (MS) the presence of magnetizable objects (SPB) can be detected by magnetizing the objects (SPB) by a magnetic field (H) delivered by a magnetic field generator (WR 1 , WR 2 ) and in which the transfer function is defined as the transfer from an electrical input signal (I in ) for generating the magnet field H, via magnetic stray field (SF) radiated by the objects (SPB) when magnetized, to an electrical output signal (I out ) delivered by the sensor (MS), comprising the steps of: - putting sample fluid on the substrate (SBSTR), the sample fluid comprising a large amount of the magnetizable objects (SPB), - attracting part of the magnetizable objects (SPB) towards the magnetic sensor (MS), - activating the electrical input signal (I in ), thereby generating the magnet field (H), - measuring the electrical output signal (I out ) as a response to the electrical input signal (I in ), - calculating the transfer function from the electrical input and output signals (I in , l out ); and a magnetic sensor (MS) on a substrate (SBSTR) in which the presence of magnetizable objects (SPB) can be detected, and presented by an electrical output signal (l out ), by magnetizing the objects (SPB) by a magnetic field (H) delivered by a magnetic field generator (WR 1 ; WR 2 ), comprising calibration means for calibrating a transfer function which is defined as the transfer from an electrical input signal (I in ) for generating the magnet field (H), via magnetic stray field (SF) radiated by the objects (SPB) when magnetized, to the electrical output signal (I out ), for executing the method.
    • 用于校准传感器(MS)的磁传感器(MS)的传递函数的方法,其中传感器(MS)可磁化物体(SPB)的存在可以通过用磁场(H)磁化物体(SPB)来检测 ),并且其中传递函数被定义为从电输入信号(I< 1> 2> 用于通过被磁化时被物体(SPB)辐射的磁性杂散场(SF)产生磁场H以产生由传感器传送的电输出信号(I OUT)的磁场H(< / SUB> MS),包括以下步骤: - 将样品流体放置在基底(SBSTR)上,样品流体包含大量可磁化物体(SPB), - 将可磁化物体(SPB)的一部分吸引到磁传感器(MS ), - 激活电输入信号(中的I ),从而产生磁场(H), - 测量电输出信号(I SUB) >)作为对电输入信号(I 中的)的响应, - 从电输入和输出信号(I SUB)中计算传递函数, ); 以及在可以检测可磁化物体(SPB)的存在的基板(SBSTR)上的磁传感器(MS),并且通过电磁输出信号(l OUT)来呈现, (SPB)通过由磁场发生器(WR< 1> 2> 2> 2)传送的磁场(H),包括用于校准传递函数的校准装置,所述传递函数被定义为 用于通过磁化时被物体(SPB)辐射的磁性杂散场(SF)的磁输入信号(H)中的电输入信号(I )的转移到电输出信号 I out ),用于执行该方法。
    • 3. 发明申请
    • MEANS AND METHOD FOR REDUCING MAGNETIC CROSS-TALK IN BIOSENSORS
    • 用于在生物传感器中减少磁性交叉的手段和方法
    • WO2006067646A2
    • 2006-06-29
    • PCT/IB2005/053933
    • 2005-11-28
    • KONINKLIJKE PHILIPS ELECTRONICS N.V.KAHLMAN, Josephus, A., H., M.DE BOER, Bart, M.
    • KAHLMAN, Josephus, A., H., M.DE BOER, Bart, M.
    • G01N27/72G01R33/09
    • G01R33/093B82Y25/00G01R33/1269
    • A magnetic sensor (MS) for sensing a magnetic stray field (SF) generated by a magnetizable object (SPB) when magnetized and for generating an electrical object signal (UOB) which depends on the sensed magnetic stray field (SF), comprising a magnetic field generator (WR 1 , WR 2 ) for generating a magnetic main field (H) for magnetizing the magnetizable object (SPB), and cross-talk reduction means for reducing the effect of a cross talk signal component in the electrical object signal (U OB ) caused by magnetic cross-talk between the magnetic main field (H) and the magnetic stray field (SF), wherein the cross-talk reduction means is arranged for distinguishing a signal property between the cross-talk signal component and the remaining part of the electrical object signal (U OB ) and for generating an electrical output signal (U O ). The signal property may for instance be the phase of a signal. In that case the cross-talk reduction means may comprise means (PHSFT) for generating an orthogonal electrical signal (U ORT ) which is orthogonal in relation to the cross-talk signal component, a multiplier (MP) for multiplying the orthogonal electrical signal (U ORT ) with the electrical object signal (U OB ), the resulting signal (U MP ) after said multiplication forming a basis for the electrical output signal (U O ). The frequency (ω 1 ) of the magnetic main field (H, H 1 ) is preferably chosen such that the phase difference between the sensed magnetic stray field (SF) and the magnetic main field (H, H 1 ) expressed in radians approximately equals π/2 +n π, in which n is an integer number. The signal property may for instance be the amplitude of a signal. In that case the magnetic main field (H) comprises a first magnetic signal (H 1 ) having a first frequency (f 1 , ω 1 ) and a second magnetic signal (H 2 ) having a second frequency (f 2 , ω 2 ) which is substantially larger than the first frequency (f 1 , ω 1 ) and which is larger than the magnetization cut-off frequency (f c ) of the magnetizable object (SPB), the first and second magnetic signals (H 1 , H 2 ) producing a first electrical signal component in the electrical object signal (U OB ) having the first frequency (f 1 ) and having a first amplitude and producing a second electrical signal component in the electrical object signal having the second frequency (f 2 ) and a second amplitude. The cross-talk reduction means comprises means (G v , MP 1 , MP 2 , DFF) for measuring the amplitudes of the first and the second electrical signal components and for mutually subtracting the measured amplitudes, the resulting signal after said subtraction forming a basis for the electrical output signal (U O ). In both cases the cross-talk reduction means may comprise a low-pass filter (LPF) for filtering said resulting signal after said subtraction, the resulting signal after said low-pass filter (LPF) being the electrical output signal (U O ).
    • 一种用于感测磁化物体(SPB)产生的磁性杂散场(SF)的磁性传感器(MS),其被磁化并且用于产生取决于感测的磁性杂散场(SF)的电对象信号(UOB),该电对象信号包括磁性 用于产生用于磁化可磁化物体(SPB)的磁主场(H)的场发生器(WR 1 SUB,WR 2),以及用于减小可磁化物体 交叉信号分量在由磁性主场(H)和磁性杂散场(SF)之间的磁场串扰引起的电气对象信号(U OB)中的影响,其中, 通话减少装置被布置用于区分串扰信号分量和电气对象信号的剩余部分(U OB OB)之间的信号特性,并用于产生电输出信号(U O )。 信号特性可以例如是信号的相位。 在这种情况下,串扰减少装置可以包括用于产生相对于串扰信号分量正交的正交电信号(U> ORT)的装置(PHSFT),乘法器(MP) 为了将正交电信号(U SUB ORT)与电气对象信号(U OB OB)相乘,在所述电信号(U SUB)之后,所得到的信号(U SUB MP&lt; 乘法形成电输出信号(U O O)的基础。 优选地,选择磁主场(H,H 1 1)的频率(α1 N 1),使得感测的磁性杂散场(SF)和 以弧度表示的磁主场(H,H 1 H 1)近似等于p / 2 + np,其中n是整数。 信号特性可以例如是信号的幅度。 在这种情况下,磁主场(H)包括具有第一频率(f 1,...,1 <1)的第一磁信号 )和具有基本上大于第一频率的第二频率(f 2 2,θ2 2)的第二磁信号(H 2 2 N) (f 1 1,...,1),并且其大于可磁化物体(SPB)的磁化截止频率(f C) 产生电对象信号(U OB OB)中的第一电信号分量的第一和第二磁信号(H 1,H 2 2) 具有第一频率并且具有第一幅度并且在具有第二频率(f 2 2 N)的电对象信号中产生第二电信号分量,并且第二频率 振幅。 串扰减少装置包括用于测量第一和第二信号的振幅的装置(G 1,V 2,MP 1,MP 2 2,DFF) 第二电信号分量并且用于相互减去测量的幅度,所述减法之后的结果信号形成电输出信号(U SUB)的基础。 在这两种情况下,串扰减少装置可以包括用于在所述减法之后对所得到的信号进行滤波的低通滤波器(LPF),所述低通滤波器(LPF)之后的结果信号是电输出信号(U SUB) 0 )。
    • 5. 发明申请
    • MAGNETIC SENSOR DEVICE WITH ROBUST SIGNAL PROCESSING
    • 具有鲁棒信号处理的磁传感器装置
    • WO2008075274A2
    • 2008-06-26
    • PCT/IB2007/055114
    • 2007-12-14
    • KONINKLIJKE PHILIPS ELECTRONICS N. V.VEEN, JeroenJANSEN, Theodorus, P., H., G.DE BOER, Bart, M.KAHLMAN, Josephus, A., H., M.
    • VEEN, JeroenJANSEN, Theodorus, P., H., G.DE BOER, Bart, M.KAHLMAN, Josephus, A., H., M.
    • G01N33/543G01R33/09G01R33/12
    • G01R33/093B82Y25/00G01R33/1269
    • The invention relates to a magnetic sensor device (100) comprising a magnetic field generator (1) driven with an excitation current of a first frequency (f 1 ) and a magnetic sensor element (e.g. a GMR sensor (2)) driven with a sensor current (I 2 ) of a second frequency (f 2 ) for measuring reaction fields (H B ) generated by magnetized particles (3). In an associated evaluation unit (10), a reference component (u Q ) of the measurement signal (u GMR ) is separated that depends on the excitation current (I 1 ) and the sensor current (I 2 ) but not on the presence of magnetized particles (3). The reference component (u Q ) may particularly be produced by a combination of the self- magnetization (H 2 ) of the magnetic sensor element (2) and cross-talk related currents. The reference component (u Q ) may be isolated based on its phase with respect to a particle-dependent component of the measurement signal (u GMR ) or based on its scaling with one of the current frequencies. Monitoring of the reference component (u Q ) reveals variations in operating conditions, for example in the sensor gain, that can be used to calibrate the measurement results.
    • 本发明涉及一种磁传感器装置(100),其包括用第一频率(f 1 1)的激励电流驱动的磁场发生器(1)和磁传感器元件(例如,GMR传感器 2)),用于产生用于测量产生的反应场(H B B)的第二频率(f 2 S 2)的传感器电流(I 2> 2 <! - SIPO GMR )的参考分量(u> QMR)被分离,该参考分量取决于激励电流(I 1)和传感器电流(I 2 2),但不存在磁化颗粒(3)。 可以特别地通过磁传感器元件(2)的自磁化(H 2 2 N 2)和串扰相关的组合来产生参考分量(u> Q) 电流。 可以基于其相对于测量信号(u> GMR>的粒子相关分量)的相位或基于其与...的比例缩放来隔离参考分量(u> Q 当前频率之一。 参考部件(u> Q )的监视显示了可用于校准测量结果的操作条件的变化,例如传感器增益。
    • 10. 发明申请
    • BIT-DETECTION ARRANGEMENT AND APPARATUS FOR REPRODUCING INFORMATION
    • 检测安排和复制信息的装置
    • WO2004109927A1
    • 2004-12-16
    • PCT/IB2004/050771
    • 2004-05-25
    • KONINKLIJKE PHILIPS ELECTRONICS N.V.RUTTEN, Albertus, J., A.VAN BEURDEN, Nicolaas, J., H., M.KAHLMAN, Josephus, A., H., M.IMMINK, Albert, H., J.
    • RUTTEN, Albertus, J., A.VAN BEURDEN, Nicolaas, J., H., M.KAHLMAN, Josephus, A., H., M.IMMINK, Albert, H., J.
    • H03L7/06
    • G11B20/10037G11B20/10009G11B20/1403H03L7/07H03L7/0994H04L7/0029H04L7/0334
    • Disclosed is a bit-detection arrangement able to convert an analog signal (AS) having an amplitude into a digital signal (DS) representing a bit sequence from which the analog signal (AS) is derived. The bit-detection arrangement has a phase detector which detect the phase difference between a quantized analog signal and a clock signal C 2 . The phase difference is sampled by an AD converter. The AD converter can sample at a relatively slow rate as the phase difference is a low frequency signal. The sampled phase difference is fed to a digital PLL which outputs a phase signal PHI. The phase signal and the quantized analog signal are used to recreate the digital signal (DS). The current invention is characterized in that the bit decision unit further comprises - at least one additional sample and hold unit SH 2 able to sample the output signal S 1 , using a clock signal C SH2 and wherein the frequency of the clock signal C SH2 is equal to the frequency of clock signal C SH1 and the phase of clock signal C SH2 is substantially different from the phase of clock signal C SH1 , and an output unit for outputting samples of either the sample and hold units SH 1 or SH 2 , wherein the samples of the sample and hold unit SH 1 are outputted when the phase signal PH 1 indicates that the phase difference ΔP 1 is in a first region and the samples of the additional sample and hold unit SH 2 are outputted when the phase signal PH 1 indicates that the phase difference ΔP 1 is in a second region. This has the advantage that the change of bit errors occurring in the presence of phase jitter is reduced.
    • 公开了一种能够将具有振幅的模拟信号(AS)转换为表示从其中导出模拟信号(AS)的比特序列的数字信号(DS)的比特检测装置。 位检测装置具有检测量化模拟信号和时钟信号C2之间的相位差的相位检测器。 相位差由AD转换器采样。 AD转换器可以以相对较慢的速率进行采样,因为相位差是低频信号。 采样相位差被馈送到输出相位信号PHI的数字PLL。 相位信号和量化的模拟信号用于重建数字信号(DS)。 本发明的特征在于,比特判定单元还包括:使用时钟信号CSH2对至少一个附加的采样和保持单元SH2进行采样,其中时钟信号CSH2的频率等于频率 时钟信号CSH1的相位和时钟信号CSH2的相位与时钟信号CSH1的相位基本不同,以及用于输出采样和保持单元SH1或SH2的采样的输出单元,其中采样和保持单元SH1的采样 当相位信号PH1指示相位差ΔP1在第一区域中时,输出相位信号PH1,并且当相位信号PH1指示相位差DeltaP1处于第二区域时,输出附加采样和保持单元SH2的采样。 这具有如下优点:在存在相位抖动的情况下发生的位错误的变化被减少。