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1. 发明申请

WO2007046013A3 PATIENT SCAN TIME OPTIMIZATION FOR PET/SPECT IMAGING 审中-公开
标题翻译：患者扫描时间优化PET / SPECT成像
公开(公告)号：WO2007046013A3
公开(公告)日：2008-01-03
申请号：PCT/IB2006053317
申请日：2006-09-15
申请人： KONINKL PHILIPS ELECTRONICS NV , NARAYANAN MANOJ , BAKKER BART , GAGNON DANIEL , FISCHER ALEXANDER , SPIES LOTHAR
发明人： NARAYANAN MANOJ , BAKKER BART , GAGNON DANIEL , FISCHER ALEXANDER , SPIES LOTHAR
IPC分类号： A61B6/00 , G01T1/29
CPC分类号： A61B6/00 , A61B6/037
摘要： An imaging system (10) comprises a data device (30), which controls radiation data acquisition from a subject positioned in an examination region (18) for an examination. A rebinning processor (40) bins the acquired data periodically into a histogram (42). A transform (70) transforms the histogram (42) into individual independent or uncorrelated components, each component including a signal content and a noise content. A stopping determining device (52) compares an aspect of at least one selected component to a predetermined threshold (TH) and, based on the comparison, terminates the data acquisition.
摘要翻译：成像系统（10）包括数据装置（30），其控制从位于检查区域（18）中的被摄体进行检查的辐射数据采集。重组处理器（40）将获取的数据周期性地存储到直方图（42）中。变换（70）将直方图（42）变换为独立的或不相关的分量，每个分量包括信号内容和噪声内容。停止确定装置（52）将至少一个所选择的组件的方面与预定阈值（TH）进行比较，并且基于该比较，终止数据采集。

2. 发明申请

WO2007034378A3 KNOWLEDGE-BASED INPUT REGION OF INTEREST DEFINITION FOR PHARMACOKINETIC MODELING 审中-公开
标题翻译：基于知识的输入区域药理学建模的兴趣定义
公开(公告)号：WO2007034378A3
公开(公告)日：2008-11-20
申请号：PCT/IB2006053265
申请日：2006-09-13
申请人： KONINKL PHILIPS ELECTRONICS NV , PHILIPS INTELLECTUAL PROPERTY , PHILIPS CORP , FISCHER ALEXANDER , SPIES LOTHAR
发明人： FISCHER ALEXANDER , SPIES LOTHAR
IPC分类号： G06T7/00
CPC分类号： G06T7/0012 , A61B5/055 , G01R33/5608 , G06K9/3233 , G06K2209/05 , G06T7/11 , G06T2207/30004
摘要： The present invention provides a system, apparatus, and method that are based on a priori knowledge of the shape of the input function for defining an input region-if- interest (ROI) in pharmacokinetic modeling. Kinetic parameter estimation requires knowledge of tracer input activity and the present invention provides an automatic way to define an ROI for estimation of an input function that takes into account a priori knowledge of the shape of the input function based on an administered dose. As a result of the application of the present invention to existing imaging analysis systems, there is a reduction in the amount of manual interaction needed and operator dependence is thereby reduced in the evaluation of dynamic procedures.
摘要翻译：本发明提供了一种系统，装置和方法，其基于用于在药代动力学建模中定义输入区域 - 如果感兴趣（ROI）的输入函数的形状的先验知识。动力学参数估计需要了解示踪剂输入活动的知识，并且本发明提供了一种自动方式来定义用于估计输入功能的ROI，其基于施用的剂量考虑到输入功能的形状的先验知识。作为将本发明应用于现有成像分析系统的结果，在动态过程的评估中减少了所需的手动交互量，从而降低了操作者依赖性。

3. 发明申请

WO2007136968A3 ERROR ADAPTIVE FUNCTIONAL IMAGING 审中-公开
标题翻译：错误自适应功能成像
公开(公告)号：WO2007136968A3
公开(公告)日：2008-05-15
申请号：PCT/US2007067848
申请日：2007-05-01
申请人： KONINKL PHILIPS ELECTRONICS NV , PHILIPS CORP , FISCHER ALEXANDER , SPIES LOTHAR , MEYER CARSTEN
发明人： FISCHER ALEXANDER , SPIES LOTHAR , MEYER CARSTEN
IPC分类号： G06T5/00
CPC分类号： G06T7/11 , G06K9/6218 , G06T2207/10104 , G06T2207/20016 , G06T2207/20021 , G06T2207/30096
摘要： A method for use in functional medical imaging includes adaptively partitioning functional imaging data as a function of a spatially varying error model. The functional image data is partitioned according to an optimization strategy. The data may be visualized or used to plan a course of treatment. In one implementation, the image data is partitioned so as to vary its spatial resolution. In another, the number of clusters is varied based on the error model.
摘要翻译：用于功能医学成像的方法包括根据空间变化的误差模型自适应地划分功能成像数据。功能图像数据根据优化策略进行分区。数据可以被可视化或用于计划治疗过程。在一个实现中，图像数据被分割以改变其空间分辨率。另一方面，群集的数量根据误差模型而变化。

4. 发明申请

WO2008096285A3 MOTION ESTIMATION IN TREATMENT PLANNING 审中-公开
标题翻译：治疗计划中的运动估计
公开(公告)号：WO2008096285A3
公开(公告)日：2008-12-04
申请号：PCT/IB2008050279
申请日：2008-01-25
申请人： KONINKL PHILIPS ELECTRONICS NV , BRINKS RALPH , MEYER CARSTEN , FISCHER ALEXANDER , GAGNON DANIEL , BUSCH MARC
发明人： BRINKS RALPH , MEYER CARSTEN , FISCHER ALEXANDER , GAGNON DANIEL , BUSCH MARC
IPC分类号： A61B6/03
CPC分类号： A61B6/032 , A61B5/055 , A61B5/721 , A61B5/7289 , A61B6/037 , A61B6/527 , A61N5/103 , A61N5/1037 , A61N5/1067 , A61N2005/1052
摘要： An apparatus includes a scanner (102, 104) and a scanning motion monitor (100). A motion modeler (116) uses data from the scanning motion monitor (100) and the scanner (102, 104) to generate a motion model which describes motion of a region of interest of an object. A treatment planner (112) uses image data from the scanner (102, 104) to establish a treatment plan for the object. A treatment device 114, which operates in conjunction with a treatment motion monitor (108), uses the motion model to compensate for motion of the object during application of the treatment.
摘要翻译：一种装置包括扫描器（102,104）和扫描运动监视器（100）。运动建模器（116）使用来自扫描运动监控器（100）和扫描器（102,104）的数据来生成描述对象的感兴趣区域的运动的运动模型。治疗计划器（112）使用来自扫描仪（102,104）的图像数据来建立对象的治疗计划。与治疗运动监测器（108）一起操作的治疗装置114使用运动模型来补偿施加治疗期间对象的运动。

5. 发明申请

WO2009153683A2 RADIOLOGICAL IMAGING INCORPORATING LOCAL MOTION MONITORING, CORRECTION, AND ASSESSMENT 审中-公开
标题翻译：包含本地运动监测，校正和评估的放射成像
公开(公告)号：WO2009153683A2
公开(公告)日：2009-12-23
申请号：PCT/IB2009052297
申请日：2009-06-01
申请人： KONINKL PHILIPS ELECTRONICS NV , PHILIPS INTELLECTUAL PROPERTY , BRINKS RALPH , FISCHER ALEXANDER , MARTIN RECUERO ANA BELEN , GEORGI JENS-CHRISTOPH , SCHWEIZER BERND , PAULUS TIMO MARKUS
发明人： BRINKS RALPH , FISCHER ALEXANDER , MARTIN RECUERO ANA BELEN , GEORGI JENS-CHRISTOPH , SCHWEIZER BERND , PAULUS TIMO MARKUS
IPC分类号： G06T11/00
CPC分类号： G06T11/005 , G06T2211/412
摘要： A radiological imaging method comprises: acquiring radiological lines of response (LOR's) from a subject; grouping the acquired LOR's into time intervals such that each group of LOR's (20) was acquired during a selected time interval; identifying a region of interest (60, 74) for each time interval based on LOR's grouped into that time interval; for each time interval, determining a positional characteristic (102) of the region of interest identified for that time interval based on LOR's grouped into that time interval; for each time interval, spatially adjusting LOR's grouped into that time interval based on the positional characteristic of the region of interest identified for that time interval; and reconstructing at least the spatially adjusted LOR's to generate a motion compensated reconstructed image.
摘要翻译：放射学成像方法包括：从受试者获取放射线响应（LOR）; 将获得的LOR分组成时间间隔，使得在选定的时间间隔内获取每组LOR（20）; 基于分组到该时间间隔中的LOR，为每个时间间隔识别感兴趣区域（60,74）; 对于每个时间间隔，基于分组到该时间间隔中的LOR确定针对该时间间隔标识的兴趣区域的位置特征（102）; 对于每个时间间隔，基于针对该时间间隔识别的感兴趣区域的位置特性，空间调整LOR被分组为该时间间隔; 以及至少重建空间调整的LOR以产生运动补偿重建图像。

6. 发明申请

WO2008015609A3 METHOD OF COMBINING BINARY CLUSTER MAPS INTO A SINGLE CLUSTER MAP 审中-公开
标题翻译：将二进制集群映射合并到单个集群映射中的方法
公开(公告)号：WO2008015609A3
公开(公告)日：2008-12-31
申请号：PCT/IB2007052843
申请日：2007-07-17
申请人： KONINKL PHILIPS ELECTRONICS NV , PHILIPS INTELLECTUAL PROPERTY , WENGLER MARK CHRISTOF , PAULUS TIMO , FISCHER ALEXANDER
发明人： WENGLER MARK CHRISTOF , PAULUS TIMO , FISCHER ALEXANDER
IPC分类号： G06T7/00
CPC分类号： G06K9/6253 , G06K9/6218 , G06K9/6292 , G06K9/6293 , G06T7/0012 , G06T7/11 , G06T7/143 , G06T2207/10072 , G06T2207/30004
摘要： This invention relates to a method of combining multiple binary cluster maps into a single cluster map; where each respective binary cluster map represents characteristic information and the single cluster map represent the sum of the characteristic information. Initially, each respective binary cluster map is assigned with a reliability factor for indicating the reliability of the binary cluster map. These factor values are then used to determine a reliability vector comprising reliability factor elements, where each respective reliability factor element is associated to certain cluster map area in the single cluster map and indicates the reliability of the cluster map area. In that way, the single cluster map can be viewed with respect to the reliability.
摘要翻译：本发明涉及一种将多个二进制簇映射组合成单个簇映射的方法; 其中每个相应的二进制聚类地图表示特征信息，并且单个聚类地图表示特征信息的总和。最初，为每个相应的二进制簇映射分配用于指示二进制簇映射的可靠性的可靠性因子。然后使用这些因子值来确定包括可靠性因素元素的可靠性向量，其中每个相应的可靠性因素元素与单个聚类地图中的某个聚类地图区域相关联并且指示聚类地图区域的可靠性。这样，就可靠性而言，可以查看单个聚类地图。

7. 发明申请

WO2008002797A3 SEMIAUTOMATIC MYOCARDIAL REGION OF INTEREST DEFINITION 审中-公开
标题翻译：利益定义的半自动心肌区域
公开(公告)号：WO2008002797A3
公开(公告)日：2009-04-30
申请号：PCT/US2007071546
申请日：2007-06-19
申请人： KONINKL PHILIPS ELECTRONICS NV , PHILIPS CORP , PHILIPS INTELLECTUAL PROPERTY , FISCHER ALEXANDER
发明人： FISCHER ALEXANDER
IPC分类号： G06T7/00 , G06T17/30
CPC分类号： G06T19/00 , G06T7/0012 , G06T7/11 , G06T17/20 , G06T2207/10104 , G06T2207/10108 , G06T2207/20156 , G06T2207/30048
摘要： A method of identifying a myocardial region of interest in cardiac medical image data is disclosed. The method includes identifying myocardial tissue (200) in first (204) and second (206) views of the medical imaging data and constructing a myocardial surface (502). In one embodiment, the myocardial surface is modeled as a plurality of elliptical arc segments (502) and a half ellipsoid.
摘要翻译：公开了一种识别心脏医学图像数据中的感兴趣心肌区域的方法。该方法包括在医学成像数据的第一（204）和第二（206）视图中识别心肌组织（200）并构建心肌表面（502）。在一个实施例中，心肌表面被建模为多个椭圆弧段（502）和半椭圆体。

8. 发明申请

WO2008015625A3 3D SEGMENTATION BY VOXEL CLASSIFICATION BASED ON INTENSITY HISTOGRAM THRESHOLDING INITIALISED BY K-MEANS CLUSTERING 审中-公开
标题翻译：基于由K-means聚类启发的强度组织阈值的VOXEL分类的3D分类
公开(公告)号：WO2008015625A3
公开(公告)日：2009-03-05
申请号：PCT/IB2007052996
申请日：2007-07-30
申请人： KONINKL PHILIPS ELECTRONICS NV , PHILIPS INTELLECTUAL PROPERTY , WENGLER MARK C , FISCHER ALEXANDER
发明人： WENGLER MARK C , FISCHER ALEXANDER
IPC分类号： G06T5/00 , G06K9/00
CPC分类号： G06K9/6218 , G06K9/033 , G06K9/38 , G06T7/11 , G06T7/136 , G06T7/143 , G06T2200/04 , G06T2207/10072 , G06T2207/20036 , G06T2207/30004
摘要： This invention relates to rearranging a cluster map of voxels in an image aiming at the reduction of sub-cluster scatter. The cluster map that includes two or more cluster levels is displayed to the user along with the distribution of the voxels within each respective cluster levels. The aim is to enable the user to evaluate the quality of the cluster map and based on the evaluation to change the distribution of the voxels. Such a change in the distribution will result in an update of the cluster map. the application discloses a method of segmentation of e.g. medical images (CT,MR) in 3D by clustering of the voxels according to their Intensities with repeated re- initalization realized by multi-thresholding of the intensity histogram.
摘要翻译：本发明涉及重新排列旨在减少子群落散射的图像中的体素的聚类映射。包含两个或多个集群级别的集群映射与每个相应集群级别中的体素分布一起显示给用户。目的是使用户能够评估集群映射的质量，并根据评估改变体素的分布。分配的这种变化将导致集群映射的更新。该应用公开了一种分割方法。医学图像（CT，MR）在3D中通过根据其强度聚类体现，通过多阈值化强度直方图实现重复重新生成。

9. 发明申请

WO2007010440A8 AUTOMATIC INPUT FUNCTION ESTIMATION FOR PHARMACOKINETIC MODELING 审中-公开
标题翻译：用于药物动力学建模的自动输入函数估计
公开(公告)号：WO2007010440A8
公开(公告)日：2007-05-18
申请号：PCT/IB2006052345
申请日：2006-07-11
申请人： KONINKL PHILIPS ELECTRONICS NV , PHILIPS CORP , FISCHER ALEXANDER , PAULUS TIMO
发明人： FISCHER ALEXANDER , PAULUS TIMO
IPC分类号： G06F19/00
CPC分类号： G06F17/18 , G16H50/50
摘要： This system ( 200 ), apparatus ( 300 ), and method ( 100 ) of the present invention provide an analytic way to solve the (input) estimation problem of pharmacokinetic modeling: estimating parameters of a kinetic model from a series of tracer (radioactively labeled imaging agent) activity measurements (e.g. by positron emission tomography). Since the model describes a biological process its parameters have a direct functional interpretation (e.g. hypoxia for the tracer FMISO) that can be of diagnostic value. The measurements represent the activity distribution in time and space in the form of a 4D data set d(t, x, y, z), t=1, . . . , T. The kinetic parameter estimation procedure ( 205 ) requires knowledge of the tracer input activity. This input activity can either be measured invasively or it can be estimated from the data in a preprocessing step. The estimation problem can be solved efficiently if the model and its input are described analytically. Typically parameterized functions (often sums of exponential terms) ( 204 ) are fitted to the averaged data over a region of interest (ROI) (e.g. an artery or the left ventricular blood pool) in order to obtain an analytical input representation. The input function representation (functional form) ( 204 ) and its initial parameter values ( 205 ) have to be selected/specified prior to the fitting procedure 206 ). The present invention thereby reduces the amount of manual interaction and operator dependence in the evaluation of dynamic procedures.

10. 发明申请

WO2005083677A3 METHOD AND SYSTEM FOR GENERATING TRAINING DATA FOR AN AUTOMATIC SPEECH RECOGNISER 审中-公开
标题翻译：用于生成自动语音识别器的培训数据的方法和系统
公开(公告)号：WO2005083677A3
公开(公告)日：2006-12-21
申请号：PCT/IB2005050518
申请日：2005-02-10
申请人： PHILIPS INTELLECTUAL PROPERTY , KONINKL PHILIPS ELECTRONICS NV , FISCHER ALEXANDER , BIPPUS ROLF DIETER
发明人： FISCHER ALEXANDER , BIPPUS ROLF DIETER
IPC分类号： G10L15/06 , G10L15/065 , G10L21/038
CPC分类号： G10L21/038 , G10L15/063 , G10L15/065 , G10L2015/0631
摘要： The invention describes a method and a system for generating training data (D T ) for an automatic speech recogniser (2) for operating at a particular first sampling frequency (f H ), comprising steps of deriving spectral characteristics (S L ) from audio data (D L ) sampled at a second frequency (f L ) lower than the first sampling frequency (f H ), extending the bandwidth of the spectral characteristics (S L ) by retrieving bandwidth extending information OBE) from a codebook (6), and processing the bandwidth extended spectral characteristics (S LE ) to give the required training data (D T ). Moreover a method and a system (5) for generating a codebook (6) for extending the bandwidth of spectral characteristics (S L ) for audio data (D L ) sampled at a second sampling frequency (f L ) to spectral characteristics (S H ) for a first sampling frequency (f H ) higher than the second sampling frequency (f L ) are described.
摘要翻译：本发明描述了一种用于产生用于在特定的第一采样频率（f H H）下操作的自动语音识别器（2）的训练数据（D SUB）的方法和系统，包括以下步骤：从低于第二频率（f L L L）采样的音频数据（D L L L）中导出频谱特性（S L L L）通过检索带宽扩展信息（SUBE OBE））来扩展频谱特性（S L1> L）的带宽的第一采样频率（f H H H）码本（6），并且处理带宽扩展频谱特性（S LE LE）以给出所需的训练数据（D SUB T）。此外，一种用于产生码本（6）的方法和系统（5），用于扩展用于在以下采样的音频数据（D L L）采样的频谱特性（D L L）的带宽的带宽对于高于第二采样的第一采样频率（f H H H），对频谱特性（S SUB H H）的第二采样频率（f L L）描述频率（fLL）。

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