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1. 发明申请

WO2005064356A2 HIGH SENSITIVITY MAGNETIC BUILT-IN CURRENT SENSOR 审中-公开
标题翻译：高灵敏度磁性内置电流传感器
公开(公告)号：WO2005064356A2
公开(公告)日：2005-07-14
申请号：PCT/IB2004052857
申请日：2004-12-20
申请人： KONINKL PHILIPS ELECTRONICS NV , DE WILDE JOHANNES , PINEDA DE GYVEZ JOSE D J , DE JONG FRANCISCUS G M , HUISKEN JOSEPHUS A , BOEVE HANS M B , PHAN LE KIM
发明人： DE WILDE JOHANNES , PINEDA DE GYVEZ JOSE D J , DE JONG FRANCISCUS G M , HUISKEN JOSEPHUS A , BOEVE HANS M B , PHAN LE KIM
IPC分类号： G01R15/20 , G01R31/30 , G01R33/09 , G11C11/15 , G11C11/16
CPC分类号： G01R31/3004 , G01R15/20 , G11C11/16 , G11C11/1673 , G11C11/1675
摘要： A sensor for contactlessly detecting currents, has a sensor element having a magnetic tunnel junction (MTJ), and detection circuitry, the sensor element having a resistance which varies with the magnetic field, and the detection circuitry is arranged to detect a tunnel current flowing through the tunnel junction. The sensor element may share an MTJ stack with memory elements. Also it can provide easy integration with next generation CMOS processes, including MRAM technology, be more compact, and use less power. Solutions for increasing sensitivity of the sensor, such as providing a flux concentrator, and for generating higher magnetic fields with a same current, such as forming L-shaped conductor elements, are given. The greater sensitivity enables less post processing to be used, to save power for applications such as mobile devices. Applications include current sensors, built-in current sensors, and IDDQ and IDDT testing, even for next generation CMOS processes.
摘要翻译：一种用于无接触地检测电流的传感器，具有具有磁性隧道结（MTJ）的传感器元件和检测电路，所述传感器元件具有随所述磁场而变化的电阻，并且所述检测电路被布置成检测流经隧道交界处。传感器元件可以与存储器元件共享MTJ堆栈。此外，它还可以提供与下一代CMOS工艺（包括MRAM技术）的轻松集成，更紧凑，功耗更低。给出了用于提高传感器灵敏度的解决方案，例如提供通量集中器，以及用于产生具有相同电流的较高磁场，例如形成L形导体元件。灵敏度越高，使用后处理的次数越少，以节省移动设备等应用的功耗。应用包括电流传感器，内置电流传感器，以及IDDQ和IDDT测试，甚至可用于下一代CMOS工艺。

2. 发明申请

WO2009122330A2 BIOCOMPATIBLE PRODUCTS FOR MAGNETIC PARTICLE IMAGING 审中-公开
标题翻译：用于磁颗粒成像的生物成分产品
公开(公告)号：WO2009122330A2
公开(公告)日：2009-10-08
申请号：PCT/IB2009051274
申请日：2009-03-26
申请人： KONINKL PHILIPS ELECTRONICS NV , MARKOV DENIS , BOEVE HANS M B
发明人： MARKOV DENIS , BOEVE HANS M B
IPC分类号： A61L27/50
CPC分类号： A61L27/24 , A61L27/18 , A61L27/50 , C08L67/04
摘要： The present invention relates to materials and methods for non-invasive imaging of biocompatible products. Biocompatible products are provided that can be visualized in vivo and in vitro using magnetic particle imaging methods. It was found that these materials can be employed for monitoring development, remodeling or degradation of biocompatible products. In another aspect, the inventive products enable substance delivery tracking and can be used to visualize targeted delivery of active agents.
摘要翻译：本发明涉及用于生物相容产品非侵入性成像的材料和方法。提供了生物相容性产品，其可以使用磁性颗粒成像方法在体内和体外可视化。发现这些材料可用于监测生物相容产品的开发，重塑或降解。在另一方面，本发明的产品能够进行物质递送跟踪，并且可以用于可视化活性剂的目标递送。

3. 发明申请

WO2009057022A3 SEPARATOR COLUMN, SEPARATOR SYSTEM, METHOD OF FRACTIONATING MAGNETIC PARTICLES, METHOD OF MANUFACTURING A SEPARATOR COLUMN AND USE OF A SEPARATOR COLUMN 审中-公开
标题翻译：分离器柱，分离器系统，分离磁性颗粒的方法，制造分离器柱的方法和分离器柱的使用
公开(公告)号：WO2009057022A3
公开(公告)日：2009-08-06
申请号：PCT/IB2008054393
申请日：2008-10-24
申请人： PHILIPS INTELLECTUAL PROPERTY , KONINKL PHILIPS ELECTRONICS NV , MARKOV DENIS , BOEVE HANS M B , GLEICH BERNHARD , WEIZENECKER JUERGEN
发明人： MARKOV DENIS , BOEVE HANS M B , GLEICH BERNHARD , WEIZENECKER JUERGEN
IPC分类号： B03C1/28 , B03C1/01 , B03C1/033
CPC分类号： B03C1/286 , A61B5/0515 , B03C1/01 , B03C1/0335 , B03C2201/18
摘要： A separator system with a separator column and a method of fractionating magnetic particles, preferably using field-flow fractionation is proposed, which allows for more effective fractionation of magnetic particles with respect to their dynamic magnetic response in a wide frequency and amplitude range of an applied magnetic field, in particular relevant for magnetic particle imaging (MPI).
摘要翻译：提出了一种具有隔离柱的分离器系统和优选使用场流分级分离磁性颗粒的方法，其允许在所施加的宽频率和振幅范围内相对于其动态磁响应更有效地分级磁性颗粒磁场，特别是与磁性粒子成像（MPI）有关。

4. 发明申请

WO2008090500A3 METHOD FOR INFLUENCING AND/OR DETECTING MAGNETIC PARTICLES IN A REGION OF ACTION, MAGNETIC PARTICLES AND THE USE OF MAGNETIC PARTICLES 审中-公开
标题翻译：影响和/或检测磁性颗粒在行动区域，磁性颗粒和磁性颗粒的使用的方法
公开(公告)号：WO2008090500A3
公开(公告)日：2008-09-12
申请号：PCT/IB2008050186
申请日：2008-01-18
申请人： KONINKL PHILIPS ELECTRONICS NV , BOEVE HANS M B , MARKOV DENIS
发明人： BOEVE HANS M B , MARKOV DENIS
IPC分类号： A61B5/00 , A61K49/00 , H01F1/00
CPC分类号： A61B5/05 , A61B5/0515 , A61K49/1818 , A61K49/1869 , B82Y25/00 , H01F1/0054 , H01F1/344
摘要： A method for influencing and/or detecting magnetic particles in a region of action, magnetic particles and the use of magnetic particles is disclosed, which method comprises the steps of: - introducing magnetic particles into a region of action, - generating a magnetic selection field having a pattern in space of its magnetic field strength such that a first sub-zone having a low magnetic field strength and a second sub-zone having a higher magnetic field strength are formed in the region of action - changing the position in space of the two sub-zones in the region of action by means of a magnetic drive field so that the magnetization of the magnetic particles change locally, - acquiring signals, which signals depend on the magnetization in the region of action, which magnetization is influenced by the change in the position in space of the first and second sub-zone, wherein the magnetic particles comprise a core region and a shell region, the core region comprising a magnetic material, wherein the magnetic material of the core region is provided as a mainly metallic material of comparably high saturation magnetization, wherein the shell region comprises mainly a metal oxide material or a nobel metal material.
摘要翻译：公开了一种用于影响和/或检测作用区域中的磁性颗粒，磁性颗粒和使用磁性颗粒的方法，该方法包括以下步骤： - 将磁性颗粒引入作用区域， - 产生磁选择场在其磁场强度的空间中具有图案，使得在该作用区域中形成具有低磁场强度的第一子区域和具有较高磁场强度的第二子区域 - 改变该区域的空间位置在作用区域中的两个子区域通过磁场驱动，使得磁性粒子的磁化局部地改变， - 获取信号，该信号取决于作用区域中的磁化，该磁化受到该变化的影响在第一和第二子区域的空间位置中，其中磁性粒子包括核心区域和壳区域，核心区域包括磁性材料其中核心区域的磁性材料被提供为具有相对高饱和磁化强度的主要金属材料，其中壳区主要包括金属氧化物材料或诺贝尔金属材料。

5. 发明申请

WO2009104151A3 ARRANGEMENT AND METHOD FOR INFLUENCING AND/OR DETECTING MAGNETIC PARTICLES IN A REGION OF ACTION OF AN EXAMINATION OBJECT AND USE OF AN ARRANGEMENT 审中-公开
标题翻译：检查和/或检测在检查对象行为区域和使用安排的磁性颗粒的布置和方法
公开(公告)号：WO2009104151A3
公开(公告)日：2009-11-05
申请号：PCT/IB2009050680
申请日：2009-02-19
申请人： KONINKL PHILIPS ELECTRONICS NV , BOEVE HANS M B
发明人： BOEVE HANS M B
IPC分类号： A61B5/05
CPC分类号： A61B5/05 , A61B5/0515 , A61B5/061 , A61B5/415 , A61B5/418 , A61B2560/0462
摘要： Arrangement for influencing and detecting magnetic particles (100) ina region of action (300) of an object (350), comprising: - selection means (210) generating, a magnetic selection field (211) having a pattern in space of its magnetic field strength such that a first sub-zone (301) having a low and a second sub-zone (302) having a higher magnetic field strength are formed in the region of action, - drive means (220) changing the position in space of the two sub- zones in the region of action by a magnetic drive field (221) so that the magnetization of the magnetic particles changes locally, - receiving means' (230) acquiring signals depending on the magnetization in the region of action, which magnetization is influenced bythe change in position in space of the first and second sub-zone, - an output device, wherein the selection means, drive means and receiving means are provided' at least partly movable relative to the object, the region of action is situated outside a space surrounding the selection means, drive means, and receiving means. Disclosed ' are methods of locating and marking lymph nodes.
摘要翻译：用于影响和检测物体（350）的作用区域（300）中的磁性颗粒（100）的装置，包括： - 选择装置（210），产生具有其磁场空间中的图案的磁选择场（211）强度使得在作用区域中形成具有较高磁场强度的低和第二子区域（302）的第一子区域（301）， - 驱动装置（220）改变空间中的位置通过磁驱动场（221）在动作区域中的两个子区域，使得磁性颗粒的磁化在局部变化， - 接收装置（230）根据作用区域中的磁化获取信号，该磁化强度是受第一和第二子区域的空间位置变化的影响， - 输出装置，其中选择装置，驱动装置和接收装置被提供为相对于物体至少部分可移动，作用区域位于外部一个空间surroun 选择装置，驱动装置和接收装置。公开的“是定位和标记淋巴结的方法。

6. 发明申请

WO2004049345A3 MAGNETIC MEMORY ARCHITECTURE WITH SHARED CURRENT LINE 审中-公开
标题翻译：具有共享电流线的磁记忆体结构
公开(公告)号：WO2004049345A3
公开(公告)日：2005-05-06
申请号：PCT/IB0305060
申请日：2003-11-06
申请人： KONINKL PHILIPS ELECTRONICS NV , BOEVE HANS M B
发明人： BOEVE HANS M B
IPC分类号： G11C11/16
CPC分类号： H01L27/222 , G11C7/02 , G11C11/16
摘要： The present invention relates to magnetic or magnetoresistive random access memories (MRAMs). The present invention provides an array with magnetoresistive memory cells arranged in logically organized rows and columns, each memory cell including a magnetoresistive element (32A, 32B). The matrix comprises a set of column lines (34), a column line (34) being a continuous conductive strip which is magnetically couplable to the magnetoresistive element (32A, 32B) of each of the memory cells of a column. A column line (34) is shared by two adjacent columns, the shared column line (34) having an area which extends over substantially the magnetoresistive elements of the two adjacent columns sharing that column line. According to the present invention, the array furthermore comprises at least one supplementary column line (36A, 36B) per column for generating a localized magnetic field in the magnetoresistive elements (32A, 32B) of one of the adjacent columns sharing the column line (34). It is an advantage of the present invention that a higher density of the memory cells can be obtained, thus reducing space required to make a MRAM memory.
摘要翻译：本发明涉及磁或磁阻随机存取存储器（MRAM）。本发明提供一种具有以逻辑组织的行和列布置的磁阻存储单元的阵列，每个存储单元包括磁阻元件（32A，32B）。矩阵包括一列列线（34），列线（34）是连续的导电条，其可与磁体每一个存储单元的磁阻元件（32A，32B）磁耦合。列线（34）由两个相邻的列共享，共享列线（34）具有一个区域，该区域基本上延伸到共享该列线的两个相邻列的磁阻元件上。根据本发明，该阵列还包括每列至少一条辅助列线（36A，36B），用于在共享列线（34）的相邻列之一的磁阻元件（32A，32B）中产生局部磁场）。本发明的优点在于，可以获得更高密度的存储单元，从而减少制造MRAM存储器所需的空间。

7. 发明申请

WO2009027937A3 CLUSTERED MAGNETIC PARTICLES AS TRACERS FOR MAGNETIC PARTICLE IMAGING 审中-公开
标题翻译：聚集的磁性颗粒作为磁性颗粒成像的追踪器
公开(公告)号：WO2009027937A3
公开(公告)日：2009-09-24
申请号：PCT/IB2008053461
申请日：2008-08-28
申请人： KONINKL PHILIPS ELECTRONICS NV , GRUELL HOLGER , BOEVE HANS M B , MARKOV DENIS
发明人： GRUELL HOLGER , BOEVE HANS M B , MARKOV DENIS
IPC分类号： A61K49/18
CPC分类号： A61K49/1812 , A61K49/1887 , B82Y5/00
摘要： The invention provides a magnetic tracer material for use in magnetic particle imaging and a manufacturing method thereof. The magnetic tracer material comprises clusters of a plurality of magnetic particles that are clustered in a controlled way to form individual entities, for example, stabilized oil droplets, solid emulsion particles, liposomes, polymersomes or vesicles, or naturally occurring biological entities such as cells or viruses.
摘要翻译：本发明提供一种用于磁性粒子成像的磁性跟踪材料及其制造方法。磁性示踪剂材料包含多个磁性颗粒的簇，其以受控的方式聚集以形成单个实体，例如稳定的油滴，固体乳液颗粒，脂质体，聚合物囊泡或囊泡，或天然存在的生物实体，例如细胞或病毒。

8. 发明申请

WO2009074952A3 ARRANGEMENT AND METHOD FOR INFLUENCING AND/OR DETECTING MAGNETIC PARTICLES IN A REGION OF ACTION 审中-公开
标题翻译：影响和/或检测行动区域中的磁性颗粒的装置和方法
公开(公告)号：WO2009074952A3
公开(公告)日：2009-09-17
申请号：PCT/IB2008055161
申请日：2008-12-09
申请人： KONINKL PHILIPS ELECTRONICS NV , BOEVE HANS M B
发明人： BOEVE HANS M B
IPC分类号： A61N1/40 , A61B5/05 , A61N2/02
CPC分类号： A61B5/05 , A61B5/0515 , A61N1/403 , A61N2/02 , A61N2/06
摘要： An arrangement and a method for influencing and/or detecting magnetic particles in a region of action is disclosed, which arrangement comprises: - selection means (210) for generating a magnetic selection field (211) having a pattern in space of its magnetic field strength such that a first sub-zone (301) having a low magnetic field strength and a second sub-zone (302) having a higher magnetic field strength are formed in the region of action (300), - drive means (220) for changing the position in space of the two sub-zones (301, 302) in the region of action (300) by means of a magnetic drive field (221) so that the magnetization of the magnetic particles (100) changes locally, - receiving means (230) for acquiring signals, which signals depend on the magnetization in the region of action (300), which magnetization is influenced by the change in the position in space of the first and second sub-zone (301, 302), - a control unit (11) for controlling the drive means and/or the selection means and/or the receiving means in such a way that - in a first mode of operation, the position in space of the two sub-zones is changed at a first frequency, and - in a second mode of operation, the position in space of the two sub-zones is changed at a second frequency, the second frequency being at least twice as high as the first frequency.
摘要翻译：公开了一种用于影响和/或检测作用区域中的磁性粒子的装置和方法，该装置包括： - 选择装置（210），用于产生具有磁场强度空间模式的磁选择场（211）使得在所述作用区域（300）中形成具有低磁场强度的第一子区域（301）和具有较高磁场强度的第二子区域（302）， - 驱动装置（220），用于改变通过磁驱动场（221）在作用区域（300）中的两个子区域（301,302）的空间中的位置使得磁性粒子（100）的磁化局部改变， - 接收装置（230），用于获取信号，该信号取决于作用区域（300）中的磁化，该磁化受到第一和第二子区域（301,302）的空间位置变化的影响， - 控制单元（11），用于控制驱动装置和/或选择装置和/或接收装置，使得 - 在第一操作模式中，两个子区域的空间位置以第一频率改变，以及 - 在第二操作模式中，空间位置两个子区中的一个以第二频率改变，第二频率至少是第一频率的两倍。

9. 发明申请

WO2004049344A3 METHOD AND DEVICE FOR IMPROVED MAGNETIC FIELD GENERATION DURING A WRITE OPERATION OF A MAGNETORESISTIVE MEMORY DEVICE 审中-公开
标题翻译：用于在磁致伸缩存储器装置的写入操作期间改善磁场生成的方法和装置
公开(公告)号：WO2004049344A3
公开(公告)日：2004-12-02
申请号：PCT/IB0305059
申请日：2003-11-06
申请人： KONINKL PHILIPS ELECTRONICS NV , BOEVE HANS M B
发明人： BOEVE HANS M B
IPC分类号： G11C11/16
CPC分类号： G11C11/1675 , G11C11/1659
摘要： The present invention relates to magnetic or magnetoresistive random access memories (MRAMs), and more particularly to a method and a device for modulating a generated magnetic field during a write operation of such a magnetoresistive memory device. The present invention provides a matrix (30) with magnetoresistive memory cells (31) logically organized in rows and columns, each memory cell (31) including a magnetoresistive element (32). The matrix (30) comprises a set of row lines (33), a row line being a continuous conductive strip which is magnetically couplable to the magnetoresistive element (32) of each of the memory cells (31) of a row. The matrix (30) also comprises a set of column lines (34), a column line (34) being a continuous conductive strip which is magnetically couplable to the magnetoresistive element (32) of each of the memory cells (31) of a column, wherein for each column line (34) at least one return column line (35) is provided for forming a return path for current in that column line (34) and for adding to a magnetic field influencing a selected magnetoresistive element (32) and generated by current flow in the column line (34) for increasing the magnetic field for writing to the selected magnetoresistive element (32).
摘要翻译：磁性或磁阻随机存取存储器技术领域本发明涉及磁性或磁阻随机存取存储器（MRAM），并且更具体地涉及用于在这种磁阻存储器装置的写入操作期间调制所产生的磁场的方法和装置。本发明提供了一种矩阵（30），其具有按行和列逻辑组织的磁阻存储单元（31），每个存储单元（31）包括磁阻元件（32）。矩阵（30）包括一组行线（33），行线是连续的导电条，其可磁性地耦合到一行的每个存储器单元（31）的磁阻元件（32）。矩阵（30）还包括一组列线（34），列线（34）是连续的导电条，其可磁性耦合到列的每个存储单元（31）的磁阻元件（32），其中为每条列线（34）提供至少一条返回列线（35），用于形成该列线（34）中的电流的返回路径并用于增加影响选定磁阻元件（32）的磁场;以及由列线（34）中的电流产生，用于增加写入所选磁阻元件（32）的磁场。

10. 发明申请

WO2006126117A2 SYSTEM COMPRISING A GENERATING DEVICE AND A COMPARING DEVICE 审中-公开
标题翻译：包含生成装置的系统和比较装置
公开(公告)号：WO2006126117A2
公开(公告)日：2006-11-30
申请号：PCT/IB2006051454
申请日：2006-05-09
申请人： KONINKL PHILIPS ELECTRONICS NV , BOEVE HANS M B , IKKINK TEUNIS J , VAN ACHT VICTOR M G
发明人： BOEVE HANS M B , IKKINK TEUNIS J , VAN ACHT VICTOR M G
IPC分类号： G05D1/02
CPC分类号： G01C17/30
摘要： Systems (1) comprising generating devices (2) comprising sensors (21) for generating sensor signals representing orientations of the generating devices (2) are provided with comparing devices (3) comprising comparators (31) for comparing the sensor signals with reference signals for interpreting the orientations, to increase the number of possible applications. The generating devices (2) and the comparing devices (3) may form parts of one apparatus (4) or of different apparatuses and then communicate wiredly or wirelessly via radio or infrared. Reference sensors (33,52) for generating the reference signals and/or reference memories (34,53) for storing the reference signals may be located in the comparing devices (3) and/or in sources (5) and then communicate wiredly or wirelessly via radio or infrared. Further comparators (36) in the comparing devices (3) may introduce adjustable sensitivities.
摘要翻译：包括生成装置（2）的系统（1）包括用于产生表示生成装置（2）的取向的传感器信号的传感器（21），比较装置（3）包括比较器（31），用于将传感器信号与参考信号进行比较解释方向，增加可能应用的数量。生成装置（2）和比较装置（3）可以形成一个装置（4）或不同装置的部分，然后通过无线电或红外线有线或无线地进行通信。用于产生参考信号的参考传感器（33,52）和/或用于存储参考信号的参考存储器（34,53）可以位于比较装置（3）和/或源（5）中，然后有线或通过无线电或红外无线方式。比较装置（3）中的进一步的比较器（36）可以引入可调节的灵敏度。

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