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1. 发明申请

WO2008012709A3 THERMOCHROMIC COMPOSITIONS FOR SKIN APPLICATION 审中-公开
标题翻译：用于皮肤应用的热变色组合物
公开(公告)号：WO2008012709A3
公开(公告)日：2008-05-29
申请号：PCT/IB2007052701
申请日：2007-07-09
申请人： KIMBERLY CLARK CO , MACDONALD JOHN GAVIN , SCHORR PHILLIP , AREHART KELLY D , BROWN TAMEKA S , LINTON LISA A , OSLUND SUSAN G
发明人： MACDONALD JOHN GAVIN , SCHORR PHILLIP , AREHART KELLY D , BROWN TAMEKA S , LINTON LISA A , OSLUND SUSAN G
IPC分类号： A61K9/14 , A61K9/16
CPC分类号： A61K8/11 , A61K9/0014 , A61K2800/412 , A61K2800/438 , A61Q17/005
摘要： Thermochromatic dyes may be added to compositions to be applied to skin in order to indicate where the composition is applied. After application to the skin the composition will turn from colored to colorless in a short period of time as its temperature rises in response to the curing reaction and to heat from the skin. The dyes are microencapsulated in order to avoid migration of the dye into the wound and to remain protected and functional. The dyes are selected such that they have a transition temperature between room temperature and that of the skin.
摘要翻译：可将热致变色染料加入待施用于皮肤的组合物中以指示组合物的施用位置。在施用于皮肤之后，随着其温度响应于固化反应和皮肤加热而升高，组合物将在短时间内从有色变为无色。将染料微胶囊化以避免染料迁移到伤口中并保持保护和功能。选择染料使得它们具有在室温和皮肤之间的转变温度。

2. 发明申请

WO2006060060A3 CHROMATOGRAPHIC CHRONOGRAPH 审中-公开
标题翻译：色谱CHRONOGRAPH
公开(公告)号：WO2006060060A3
公开(公告)日：2007-02-01
申请号：PCT/US2005035497
申请日：2005-09-30
申请人： KIMBERLY CLARK CO , MACDONALD JOHN GAVIN , AREHART KELLY D
发明人： MACDONALD JOHN GAVIN , AREHART KELLY D
IPC分类号： G04F13/04
CPC分类号： G04F1/06 , A61F13/42 , G04F1/00 , G04F13/04 , G04F13/06
摘要： A timer indicator or chronograph is described. The chronograph functions according to chromatographic principles to develop a perceptible visual image or pattern on an indicator panel or display area, which serves as a means to monitor the relative amount of time that elapses. The chronograph includes a self-contained reservoir for an activating agent, which once activated creates a mobile front that traverses the indicator panel substrate from the reservoir to a distal end at a predetermined rate. The chronograph may be used as a stand-alone device or may be incorporated as part of various articles or products, for instance, as either a training aid or as a dryness indicator. Methods for using and making the chronograph are also described.
摘要翻译：描述了定时器指示器或计时码表。计时码表根据色谱原理起作用，以在显示面板或显示区域上形成一个可察觉的视觉图像或图案，这是监测经过的相对时间量的一种手段。计时码表包括用于激活剂的独立储存器，其一旦被激活就产生以预定速率从储存器穿过指示器面板基底到远端的移动前部。计时码表可以用作独立设备，也可以作为各种物品或产品的一部分来使用，例如作为训练助剂或干燥指示剂。还描述了使用和制造计时码表的方法。

3. 发明申请

WO2007119185A3 DEGRADABLE THERAPEUTIC DELIVERY DEVICE 审中-公开
标题翻译：可降解的治疗设备
公开(公告)号：WO2007119185A3
公开(公告)日：2008-03-27
申请号：PCT/IB2007051157
申请日：2007-03-30
申请人： KIMBERLY CLARK CO , SMITH MOLLY K , AREHART KELLY D , HUANG LEI , YANG SHU-PING , HUANG YANBIN
发明人： SMITH MOLLY K , AREHART KELLY D , HUANG LEI , YANG SHU-PING , HUANG YANBIN
IPC分类号： A61K9/00 , A61K47/34 , A61L27/18 , A61L27/54 , A61L27/58 , A61L31/06 , A61L31/14 , A61L31/16 , A61M31/00
CPC分类号： A61K47/34 , A61F6/08 , A61K9/0036 , A61K31/00 , A61K31/19 , A61M31/002 , C08G63/12 , C08G63/16 , C08G63/914
摘要： A biodegradable biodelivery device is disclosed. The biodelivery device is formed from a polymer comprising the reaction product of a polyol and a polyacid. When exposed to water, the polymer degrades through hydrolysis. Of particular advantage, the polymer can be formed so as to be elastic and flexible. In one embodiment, the polymer is formed into a vaginal insert. As the polymer degrades, the polymer releases acid to a vaginal environment for decreasing the pH of the environment.
摘要翻译：公开了一种可生物降解的生物输送装置。生物输送装置由包含多元醇和多元酸的反应产物的聚合物形成。当暴露于水时，聚合物通过水解降解。特别有利的是，聚合物可以形成为具有弹性和柔性。在一个实施方案中，聚合物形成阴道插入物。当聚合物降解时，聚合物将酸释放到阴道环境中以降低环境的pH。

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