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1. 发明申请

WO2007053507A1 MRI COMPATIBLE IMPLANTED ELECTRONIC MEDICAL DEVICE 审中-公开
标题翻译： MRI兼容植入电子医疗器械
公开(公告)号：WO2007053507A1
公开(公告)日：2007-05-10
申请号：PCT/US2006/042195
申请日：2006-10-30
申请人： KENERGY, INC. , DENKER, Stephen , BEUTLER, Arthur, J. , BULKES, Cherik
发明人： DENKER, Stephen , BEUTLER, Arthur, J. , BULKES, Cherik
IPC分类号： A61N1/16 , A61N1/37 , G01R33/422
CPC分类号： A61N1/375 , A61N1/086 , A61N1/3718
摘要： An implantable electronic medical device is compatible with a magnetic resonance imaging (MRI) scanner. The device has a housing with exterior walls, each formed by a dielectric substrate with electrically conductive layers on interior and exterior surfaces. A series of slots divide each layer into segments. Segmenting the layers provides high impedance to eddy currents produced by fields of the MRI scanner, while capacitive coupling of the segments provides radio frequency shielding for components inside the housing. Electrical leads extending from the housing have a pair of coaxially arranged conductors and traps that attenuate currents induced in the conductors by the fields of the MRI scanner.
摘要翻译：可植入电子医疗装置与磁共振成像（MRI）扫描器兼容。该装置具有带有外壁的壳体，每个由内部和外部表面上具有导电层的电介质基底形成。一系列插槽将每个层划分成多个段。这些层的分段对于由MRI扫描仪的场产生的涡流提供高阻抗，而段的电容耦合为壳体内的部件提供射频屏蔽。从壳体延伸的电引线具有一对同轴布置的导体和陷阱，其通过MRI扫描仪的场来衰减在导体中感应的电流。

2. 发明申请

WO2006115877A1 VAGAL NERVE STIMULATION USING VASCULAR IMPLANTED DEVICES FOR TREATMENT OF ATRIAL FIBRILLATION 审中-公开
标题翻译： VAGAL神经刺激使用血管植入装置治疗ATRIAL FIBRILLATION
公开(公告)号：WO2006115877A1
公开(公告)日：2006-11-02
申请号：PCT/US2006/014387
申请日：2006-04-18
申请人： KENERGY, INC. , DENKER, Stephen , BULKES, Cherik , BEUTLER, Arthur, J.
发明人： DENKER, Stephen , BULKES, Cherik , BEUTLER, Arthur, J.
IPC分类号： A61N1/372 , A61N1/39 , A61N1/36
CPC分类号： A61N1/36114 , A61N1/37205 , A61N1/37211 , A61N1/3787 , A61N1/395
摘要： An abnormally rapid ventricular cardiac rate that results from atrial fibrillation can be reduced by stimulating a vagal nerve of the heart. An apparatus for such stimulation includes a power transmitter that emits a radio frequency signal. A stimulator, implanted in a blood vessel adjacent the vagal nerve, has a pair of electrodes and an electrical circuit thereon. The electrical circuit receives the radio frequency signal and derives an electrical voltage from the energy of that signal. The electrical voltage is applied in the form of pulses to the pair of electrodes, thereby stimulating the vagal nerve. The pattern of that stimulating pulses can be varied in response to characteristics of the atrial fibrillation or the ventricular contractions.
摘要翻译：通过刺激心脏的迷走神经可以减少心房颤动引起的异常快速的心室心率。用于这种刺激的装置包括发射射频信号的功率发射器。植入在迷走神经附近的血管中的刺激器在其上具有一对电极和电路。电路接收射频信号，并根据该信号的能量导出电压。以脉冲的形式将电压施加到该对电极，从而刺激迷走神经。刺激脉冲的模式可以响应于心房颤动或心室收缩的特征而变化。

3. 发明申请

WO2007001871A1 DOUBLE HELICAL ANTENNA ASSEMBLY FOR A WIRELESS INTRAVASCULAR MEDICAL DEVICE 审中-公开
标题翻译：无线静脉医疗设备的双耳螺旋天线装置
公开(公告)号：WO2007001871A1
公开(公告)日：2007-01-04
申请号：PCT/US2006/023254
申请日：2006-06-15
申请人： KENERGY, INC. , DENKER, Stephen , BULKES, Cherik , BEUTLER, Arthur, J.
发明人： DENKER, Stephen , BULKES, Cherik , BEUTLER, Arthur, J.
IPC分类号： A61N1/372 , A61N1/375
CPC分类号： A61N1/37229 , A61N1/375
摘要： A medical device, such as a cardiac pacing device for an animal, includes an intravascular antenna that has a first coil for engaging a wall of a first blood vessel to receive a radio frequency signal. The first coil includes a first winding wound helically in a rotational direction along a longitudinal axis from a first end of the coil to a second end. A second winding that is connected to the a first winding at the second end, is wound helically in the same rotational direction along the longitudinal axis from the second end to the first end. An electronic circuit is implanted in the animal and is connected to the antenna to receive an electrical signal therefrom.
摘要翻译：诸如用于动物的心脏起搏装置的医疗装置包括血管内天线，其具有用于接合第一血管的壁以接收射频信号的第一线圈。第一线圈包括沿着从线圈的第一端到第二端的纵向轴线的旋转方向螺旋形地缠绕的第一线圈。在第二端连接到第一绕组的第二绕组沿着从第二端到第一端的纵向轴线在相同的旋转方向上螺旋地卷绕。将电子电路注入动物并连接到天线以从其接收电信号。

4. 发明申请

WO2007061654A3 ALERTING METHOD FOR A TRANSVASCULAR TISSUE STIMULATION SYSTEM 审中-公开
公开(公告)号：WO2007061654A3
公开(公告)日：2007-05-31
申请号：PCT/US2006/043878
申请日：2006-11-09
申请人： KENERGY, INC. , DENKER, Stephen , BEUTLER, Arthur, J. , BULKES, Cherik
发明人： DENKER, Stephen , BEUTLER, Arthur, J. , BULKES, Cherik
IPC分类号： A61N1/00
摘要： A system for stimulating tissue of the patient includes an implantable medical device and an external power source. The medical device receives and extracts electrical energy from a first wireless signal and has a detector circuit that senses a physiological characteristic of the patient. The sensing can occur simultaneously while electrical stimulation pulses are applied to the tissue. A feedback transmitter that sends information related to the physiological characteristic via a second wireless signal. The external power source transmits the first wireless signal and extracts the information from a second wireless signal. When the information indicates existence of a predefined condition, a communication module, that preferably includes a cellular telephone sends a message for reception by the remote monitor to alert medical personnel.

5. 发明申请

WO2007053508A1 INTRAVASCULAR ELECTRONICS CARRIER AND ELECTRODE FOR A TRANSVASCULAR TISSUE STIMULATION SYSTEM 审中-公开
标题翻译：血管内电刺激系统的电子载体和电极
公开(公告)号：WO2007053508A1
公开(公告)日：2007-05-10
申请号：PCT/US2006/042196
申请日：2006-10-30
申请人： KENERGY, INC. , DENKER, Stephen , BEUTLER, Arthur, J. , BULKES, Cherik
发明人： DENKER, Stephen , BEUTLER, Arthur, J. , BULKES, Cherik
IPC分类号： A61N1/36
CPC分类号： A61N1/372 , A61N1/362 , A61N1/37205 , A61N1/375
摘要： An intravascular mesh type electrode carrier eliminates material and mechanical transitions between an electrical lead and an electrode by interweaving the conductor of the lead into the carrier mesh. The mesh material of the electrode carrier can be electrically conductive so that the entire carrier functions as the electrode. Alternatively, the mesh material may either be non-conductive or have an outer non-conductive coating, in which cases only the exposed section of the first conductor acts as an electrode. With a non-conductive mesh material, a second electrode lead can be woven through the mesh of the electrode carrier to provide a second electrode.
摘要翻译：血管内网状电极载体通过将导体的导体交织到载体网中来消除电引线和电极之间的材料和机械转变。电极载体的网状材料可以是导电的，使得整个载体用作电极。或者，网状材料可以是不导电的或具有外部非导电涂层，其中仅第一导体的暴露部分用作电极。利用非导电网状材料，可以通过电极载体的网格编织第二电极引线以提供第二电极。

6. 发明申请

WO2007041675A1 RADIO FREQUENCY ANTENNA FOR A WIRELESS INTRAVASCULAR MEDICAL DEVICE 审中-公开
标题翻译：无线静脉医疗器械无线电天线
公开(公告)号：WO2007041675A1
公开(公告)日：2007-04-12
申请号：PCT/US2006/038954
申请日：2006-10-03
申请人： KENERGY, INC. , DENKER, Stephen , BULKES, Cherik , BEUTLER, Arthur, J.
发明人： DENKER, Stephen , BULKES, Cherik , BEUTLER, Arthur, J.
IPC分类号： H01Q1/27 , H01Q1/40 , H01Q7/00 , A61N1/372
CPC分类号： A61N1/3787 , A61N1/37205 , A61N1/37229 , H01Q1/273 , H01Q1/40 , H01Q7/00
摘要： A radio frequency antenna is provided for use with a medical device for implantation into an animal. The antenna comprises a coil (40) formed by a wire (50) that includes a core (52) formed of a shape-memory material with an electrically conductive first layer (54) applied to an outer surface of the core. A second layer (60) , of an electrically insulating and biologically compatible material, extends around the first layer. If necessary to reduce friction a lubricant (58) is placed between the first and second layers. If second layer is formed of porous material or a non-biological compatible material, a biological compatible outer layer (62) surrounds the second layer thereby providing a barrier that is impermeable to body fluids of the animal.
摘要翻译：提供射频天线用于与用于植入动物的医疗装置一起使用。天线包括由线（50）形成的线圈（40），线（50）包括由形状记忆材料形成的芯（52），导电第一层（54）施加到芯的外表面。电绝缘和生物相容的材料的第二层（60）围绕第一层延伸。如果需要减少摩擦，则在第一和第二层之间放置润滑剂（58）。如果第二层由多孔材料或非生物相容的材料形成，则生物相容的外层（62）围绕第二层，从而提供对动物的体液不可透过的屏障。

7. 发明申请

WO2008019384A1 INTRAVASCULAR IMPLANT SYSTEM 审中-公开
标题翻译：静脉内植入系统
公开(公告)号：WO2008019384A1
公开(公告)日：2008-02-14
申请号：PCT/US2007/075453
申请日：2007-08-08
申请人： KENERGY, INC. , BULKES, Cherik , DENKER, Stephen , BEUTLER, Arthur, J.
发明人： BULKES, Cherik , DENKER, Stephen , BEUTLER, Arthur, J.
IPC分类号： A61N1/36
CPC分类号： A61N1/3622 , A61N1/36017 , A61N1/3627 , A61N1/37205 , A61N1/375 , A61N1/3787
摘要： An intravascular implantable system for providing electrical stimulation of tissue inside an animal to deal with a clinical condition is described. The system comprises a power supply module supplying energy to the implantable system, an implanted control module controlling operation of the implantable system and producing desired digital waveforms. Each desired digital waveform has an envelope with a predetermined attribute. An implanted intravascular sensing module sensing at least one parameter of interest for the purpose of dealing with the clinical condition. An intravascular stimulation module is provided to electrically stimulate the tissue with an output waveform that is substantially similar to the desired digital waveform produced by the control module.
摘要翻译：描述了用于对动物内的组织进行电刺激以处理临床状况的血管内可植入系统。该系统包括向可植入系统供应能量的电源模块，控制可植入系统的操作并产生所需数字波形的植入式控制模块。每个期望的数字波形具有具有预定属性的信封。植入的血管内感测模块感测至少一个感兴趣的参数以便处理临床状况。提供血管内刺激模块以用与控制模块产生的期望数字波形基本相似的输出波形电刺激组织。

8. 发明申请

WO2007081714A1 EXTRACORPOREAL POWER SUPPLY WITH A WIRELESS FEEDBACK SYSTEM FOR AN IMPLANTED MEDICAL DEVICE 审中-公开
标题翻译：具有用于医疗设备的无线反馈系统的超级电源
公开(公告)号：WO2007081714A1
公开(公告)日：2007-07-19
申请号：PCT/US2007/000094
申请日：2007-01-04
申请人： KENERGY, INC , DENKER, Stephen , BULKES, Cherik , BEUTLER, Arthur, J.
发明人： DENKER, Stephen , BULKES, Cherik , BEUTLER, Arthur, J.
IPC分类号： A61N1/372 , A61N1/378 , A61M1/12
CPC分类号： A61N1/3787
摘要： A medical device adapted for implantation into a patient receives electrical power from an extracorporeal power supply. The medical device has a first receiver for a first wireless signal, a power circuit that extracts energy from the first wireless signal to power the medical device, and a feedback signal generator that transmits a second wireless signal indicating a magnitude of energy extracted from the first wireless signal. The extracorporeal power supply includes a source of electrical power and a power transmitter that emits the first wireless signal. A second receiver enables the extracorporeal power supply to receive the second wireless signal. A feedback controller manipulates the first wireless signal in response to the second wireless signal to ensure that sufficient electrical energy is provided to the medical device without wasting electrical power from the source.
摘要翻译：适于植入患者的医疗装置从体外电源接收电力。医疗设备具有用于第一无线信号的第一接收器，从第一无线信号提取能量以为医疗设备供电的电源电路;以及反馈信号发生器，其发送指示从第一无线信号提取的能量大小的第二无线信号无线信号。体外电源包括电源和发射第一无线信号的功率发射器。第二接收器使得体外电源能够接收第二无线信号。反馈控制器响应于第二无线信号操纵第一无线信号，以确保向医疗设备提供足够的电能，而不会浪费源的电力。

9. 发明申请

WO2007100696A2 MAGNETIC RESONANCE IMAGING SYSTEM WITH A CLASS-E RADIO FREQUENCY AMPLIFIER 审中-公开
标题翻译：具有等级无线电频率放大器的磁共振成像系统
公开(公告)号：WO2007100696A2
公开(公告)日：2007-09-07
申请号：PCT/US2007/004794
申请日：2007-02-23
申请人： DENKER, Stephen , BULKES, Cherik , BEUTLER, Arthur, J.
发明人： DENKER, Stephen , BULKES, Cherik , BEUTLER, Arthur, J.
IPC分类号： G01R33/36 , G01R33/34
CPC分类号： G01R33/34076 , G01R33/34046 , G01R33/3453 , G01R33/3614
摘要： A Class-E amplifier has bee adapted for use in the radio frequency section of a magnetic resonance imaging (MRI) system. A drive signal is produces by modulating the envelope of a radio frequency carrier signal and then applied to a switch in the Class-E amplifier. The switch is connected in series with a choke between a supply voltage terminal and circuit ground with an output node formed between the choke and the switch. The output node is coupled to circuit ground by a shunt capacitor. In a preferred embodiment, a pair of such amplifiers, that are II radians out of phase, are connected to each rung of a transverse electromagnetic transmit array type radio frequency coil of the MRI system.
摘要翻译： E类放大器适用于磁共振成像（MRI）系统的射频部分。通过调制射频载波信号的包络产生驱动信号，然后将其应用于E类放大器中的开关。开关与电源电压端子和电路接地之间的扼流器串联连接，并在扼流圈和开关之间形成输出节点。输出节点通过并联电容耦合到电路接地。在一个优选实施例中，一对这样的放大器，即异相II弧形，连接到MRI系统的横向电磁发射阵列型射频线圈的每个梯级。

10. 发明申请

WO2007100697A2 CLASS-E RADIO FREQUENCY POWER AMPLIFIER WITH FEEDBACK CONTROL 审中-公开
标题翻译：带反馈控制的E类射频功率放大器
公开(公告)号：WO2007100697A2
公开(公告)日：2007-09-07
申请号：PCT/US2007/004795
申请日：2007-02-23
申请人： DENKER, Stephen , BULKES, Cherik , BEUTLER, Arthur, J.
发明人： DENKER, Stephen , BULKES, Cherik , BEUTLER, Arthur, J.
IPC分类号： A61N1/378 , H03F3/217
CPC分类号： A61N1/3787 , H03F1/34 , H03F3/217 , H03F3/2176 , H03F2200/351
摘要： A Class-E power amplifier includes a choke and a switch connected in series between a source of a supply voltage and circuit ground and connected to an inductively coupled coil. An output node of the amplifier is formed between choke and the switch and connected to a transmitter antenna. A shunt capacitor couples the amplifier's output node to the circuit ground. A feedback signal, indicating an intensity if the signal at the amplifier output node is used to vary the input signal to the Class-E power amplifier and thereby control operation of the switch.
摘要翻译： E类功率放大器包括串联连接在电源电压源和电路接地之间并连接到电感耦合线圈的扼流圈和开关。放大器的输出节点形成在扼流圈和开关之间并连接到发射机天线。并联电容器将放大器的输出节点连接到电路的地。反馈信号，指示放大器输出节点处的信号用于改变输入到E类功率放大器的输入信号并由此控制开关的操作的强度。

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