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1. 发明申请

WO2009117421A2 HETEROCYCLIC MODULATORS OF GPR119 FOR TREATMENT OF DISEASE 审中-公开
标题翻译： GPR119用于治疗疾病的杂环调节剂
公开(公告)号：WO2009117421A2
公开(公告)日：2009-09-24
申请号：PCT/US2009/037408
申请日：2009-03-17
申请人： KALYPSYS, INC. , SMITH, Nicholas , BONNEFOUS, Celine , GOVEK, Steven P. , WU, Dongpei , PINKERTON, Anthony B. , KAHRAMAN, Mehmet , COOK, Travis , NOBLE, Stewart A. , BORCHARDT, Allen J. , PRINS, Thomas
发明人： SMITH, Nicholas , BONNEFOUS, Celine , GOVEK, Steven P. , WU, Dongpei , PINKERTON, Anthony B. , KAHRAMAN, Mehmet , COOK, Travis , NOBLE, Stewart A. , BORCHARDT, Allen J. , PRINS, Thomas
IPC分类号： C07D271/04 , A61P9/00
CPC分类号： C07D401/14 , C07D207/34 , C07D277/56 , C07D401/04 , C07D401/12 , C07D403/10 , C07D405/14 , C07D413/12 , C07D413/14
摘要： The present invention relates to compounds and methods which may be useful as inhibitors of GPR119 for the treatment or prevention of metabolic, cardiovascular, and metabolic diseases.
摘要翻译：本发明涉及可用作GPR119抑制剂用于治疗或预防代谢，心血管和代谢疾病的化合物和方法。

2. 发明申请

WO2006063294A2 NOVEL INHIBITORS OF HISTONE DEACETYLASE FOR THE TREATMENT OF DISEASE 审中-公开
标题翻译：用于治疗疾病的组蛋白脱乙酰酶的新型抑制剂
公开(公告)号：WO2006063294A2
公开(公告)日：2006-06-15
申请号：PCT/US2005/044743
申请日：2005-12-09
申请人： KALYPSYS, INC. , MALECHA, James , NOBLE, Stewart , HASSIG, Christian , WASH, Paul , WILEY, Brandon , LAWRENCE, Charles , HOFFMAN, Timothy , BONNEFOUS, Celine , SMITH, Nicholas
发明人： MALECHA, James , NOBLE, Stewart , HASSIG, Christian , WASH, Paul , WILEY, Brandon , LAWRENCE, Charles , HOFFMAN, Timothy , BONNEFOUS, Celine , SMITH, Nicholas
IPC分类号： C07C323/22 , C07D217/04 , C07D213/38 , C07D215/38 , A61K31/145 , A61K31/4402 , A61K31/47 , A61K31/472 , A61P35/00
CPC分类号： C07D213/74 , C07C327/22 , C07C327/28 , C07C327/30 , C07C327/32 , C07D213/32 , C07D213/70 , C07D215/36 , C07D215/38 , C07D231/38 , C07D241/44 , C07D295/192 , C07D295/26 , C07D319/18
摘要： Disclosed herein are carbonyl compounds of Formula: (I) as described herein. Compounds as modulators of histone deacetylase (HDAC), pharmaceutical compositions comprising the same, and methods of treating disease using the same are disclosed.
摘要翻译：本文公开的是如本文所述的式（I）的羰基化合物。公开了作为组蛋白脱乙酰酶（HDAC）的调节剂的化合物，包含其的药物组合物和使用其的治疗疾病的方法。

3. 发明申请

WO2011057327A1 ANTI-INFLAMMATORY EXTRACT 审中-公开
标题翻译：抗炎提取物
公开(公告)号：WO2011057327A1
公开(公告)日：2011-05-19
申请号：PCT/AU2010/001497
申请日：2010-11-10
申请人： UNIVERSITY OF SOUTH AUSTRALIA , CHUULANGUN ABORIGINAL CORPORATION , SEMPLE, Susan, Jean , SIMPSON, Bradley, Scott , CLAUDIE, David, John , WANG, Jiping , SMITH, Nicholas , MCKINNON, Ross, Allan
发明人： SEMPLE, Susan, Jean , SIMPSON, Bradley, Scott , CLAUDIE, David, John , WANG, Jiping , SMITH, Nicholas , MCKINNON, Ross, Allan
IPC分类号： A61K36/77 , A61K31/37 , A61K31/34 , A61P29/00
CPC分类号： A61K31/34 , A61K31/37 , A61K36/77
摘要： The present invention provides anti-inflammatory extracts derived from plants of the Dodonaeoideae subfamily. The present invention also provides a method for preparing an anti-inflammatory extracts. Other aspects of the present invention also relate to pharmaceutical compositions comprising anti-inflammatory extracts and methods of treating or preventing inflammation in a subject.
摘要翻译：本发明提供衍生自Dodonaeoideae亚科植物的抗炎提取物。本发明还提供了制备抗炎提取物的方法。本发明的其它方面还涉及包含抗炎提取物和治疗或预防受试者炎症的方法的药物组合物。

4. 发明申请

WO2010115870A1 OPTOMETRIC TESTING SYSTEM 审中-公开
标题翻译： OPTOMETRIC测试系统
公开(公告)号：WO2010115870A1
公开(公告)日：2010-10-14
申请号：PCT/EP2010/054505
申请日：2010-04-06
申请人： CITY UNIVERSITY , ZHU, Haogang , SMITH, Nicholas , CRABB, David , GRUPPETTA, Stephen
发明人： ZHU, Haogang , SMITH, Nicholas , CRABB, David , GRUPPETTA, Stephen
IPC分类号： A61B3/032
CPC分类号： A61B3/032 , A61B3/113
摘要： This invention relates to an optometric testing system (1, 47) that comprises: a test presentation device (7, 53) for presenting optical tests to a subject; a data store (3, 49) for a library of different optometric tests, each said test comprising instructions for providing optical stimuli to a subject; a control module (5, 51 ) responsive to the instructions stored in said data store (3, 49) for a selected test to control the test presentation device (7, 53) to provide the stimuli for that test to the subject; and an input interface (9, 55) operable by the subject to generate signals in response to the stimuli of a selected test that are presented to said subject; said control module (5, 51 ) being configured to receive said signals from said input interface (9, 55) in response to the stimuli of said selected test.
摘要翻译：本发明涉及一种验光测试系统（1,47），其包括：用于向对象呈现光学测试的测试呈现设备（7,53）; 用于不同验光测试的库的数据存储器（3,49），每个所述测试包括用于向对象提供光学刺激的指令; 响应于存储在所述数据存储器（3,49）中的指令的控制模块（5,51）用于选择的测试，以控制所述测试呈现设备（7,53）向所述对象提供所述测试的刺激; 以及可由对象操作以响应于呈现给所述对象的所选择的测试的刺激而产生信号的输入接口（9,55）所述控制模块（5,51）被配置为响应于所述选择的测试的刺激从所述输入接口（9,55）接收所述信号。

5. 发明申请

WO2003029210A3 HETEROARYL SUBSTITUTED TETRAZOLE MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR-5 审中-公开
公开(公告)号：WO2003029210A3
公开(公告)日：2003-04-10
申请号：PCT/US2002/031294
申请日：2002-10-01
申请人： MERCK & CO. INC. , COSFORD, Nicholas, D. , ROPPE, Jeffrey , CHEN, Chixu , SMITH, Nicholas , REGER, Thomas
发明人： COSFORD, Nicholas, D. , ROPPE, Jeffrey , CHEN, Chixu , SMITH, Nicholas , REGER, Thomas
IPC分类号： C07D401/06
摘要： Tetrazole compounds substituted directly, or by a bridge, with a heteroaryl moiety containing N adjacent to the point of connection of the heteroaryl, are mGluR5 modulators useful in the treatment of psychiatric and mood disorders such as, for example, schizophrenia, anxiety, depression, and panic, as well as in the treatment of pain and other diseases.

6. 发明申请

WO2016003938A1 GROUND TRACKING APPARATUS, SYSTEMS, AND METHODS 审中-公开
标题翻译：接地跟踪设备，系统和方法
公开(公告)号：WO2016003938A1
公开(公告)日：2016-01-07
申请号：PCT/US2015/038377
申请日：2015-06-29
申请人： SEESCAN, INC. , OLSSON, Mark , POWELL, Scott , SMITH, Nicholas , LEVIN, Ryan , KOK, Thomas , MARTIN, Michael , NEWBY, Garrett
发明人： OLSSON, Mark , POWELL, Scott , SMITH, Nicholas , LEVIN, Ryan , KOK, Thomas , MARTIN, Michael , NEWBY, Garrett
IPC分类号： G01C3/22 , G01V3/15 , G01C5/00 , G01C3/20
CPC分类号： G01C5/00 , G01C3/20 , G01V3/15
摘要： Apparatus, systems, and methods are disclosed for tracking movement over the ground or other surfaces using two or more spaced apart cameras and an associated processing element to detect ground features in images from the cameras and determine tracking parameters based on the position of the detected ground features in the images.
摘要翻译：公开了用于使用两个或更多间隔开的照相机跟踪地面或其它表面上的移动的装置，系统和方法，以及相关联的处理元件，以检测来自照相机的图像中的地面特征，并且基于检测到的地面的位置确定跟踪参数图像中的特征。

7. 发明申请

WO2022150829A1 SKATEBOARD TRUCK MOUNTING APPARATUS 审中-公开
公开(公告)号：WO2022150829A1
公开(公告)日：2022-07-14
申请号：PCT/US2022/070069
申请日：2022-01-06
申请人： SMITH, Nicholas
发明人： SMITH, Nicholas
IPC分类号： A63C17/00 , A63C17/01 , A63C17/02 , A63C17/04
摘要： A skateboard truck mounting apparatus is provided. The skateboard truck mounting apparatus includes a rigid body, having a first hole and a second hole, where the holes are configured to interface with the holes on a skateboard deck. Both the first hole and the second hole are equipped with self-locking mechanisms.

8. 发明申请

WO2014025451A1 MULTI-CAMERA PIPE INSPECTION APPARATUS, SYSTEMS AND METHODS 审中-公开
标题翻译：多相机管道检测装置，系统和方法
公开(公告)号：WO2014025451A1
公开(公告)日：2014-02-13
申请号：PCT/US2013/045000
申请日：2013-06-10
申请人： OLSSON, Mark , CHAPMAN, Eric , SMITH, Nicholas
发明人： OLSSON, Mark , CHAPMAN, Eric , SMITH, Nicholas
IPC分类号： H04N5/225 , A61B1/05 , G02B23/24
CPC分类号： G01N21/8803 , A61B1/00193 , A61B1/05 , G02B13/06 , G02B23/243 , G02B23/2484 , H04N5/2252 , H04N5/2258 , H04N2005/2255
摘要： A camera head for inspecting pipes or cavities including an array of two or more imaging elements with overlapping Fields of View (FOV) is disclosed. The camera head may include one or more light source elements, such as LEDs, for providing illumination in dimly lit inspection sites, such as the interior of underground pipes. The imaging elements and LEDs may be used in conjunction with a remote display device, such as an LCD panel of a camera control unit (CCU) or monitor in proximity to an operator, to display the interior of a pipe or other cavity.
摘要翻译：公开了一种用于检查包括具有重叠视场（FOV）的两个或多个成像元件的阵列的管道或腔的摄像头。相机头可以包括一个或多个光源元件，例如LED，用于在昏暗的检查位置（例如地下管道的内部）中提供照明。成像元件和LED可以与诸如照相机控制单元（CCU）的LCD面板或靠近操作者的监视器的远程显示设备结合使用，以显示管道或其他空腔的内部。

9. 发明申请

WO2010118434A2 APPARATUS, SYSTEM, AND METHOD FOR ORGANIZATIONAL MERGER AND ACQUISITION ANALYSIS 审中-公开
标题翻译：用于组织合并和收购分析的装置，系统和方法
公开(公告)号：WO2010118434A2
公开(公告)日：2010-10-14
申请号：PCT/US2010/030772
申请日：2010-04-12
申请人： SMITH, Nicholas , CARRIER, Rebecca
发明人： SMITH, Nicholas , CARRIER, Rebecca
IPC分类号： G06Q10/00 , G06Q50/00
CPC分类号： G06Q10/00 , G06Q10/0637 , G06Q30/0203
摘要： An apparatus, system, and method are disclosed for merger and acquisition analysis. A survey module 202 may provide 1606 a survey regarding organizational aspects 402, including both subjective aspects and objective aspects. A database module 204 may gather 1608 responses to the survey regarding a first company and a second company that are merger candidates into a database of survey data. A reporting module 206 may display 1612, 1624, or 1634 a graphic that presents a visual summary 600, 1100, or 1200 of the survey data for each organizational aspect 402. A recommendation module 108 may generate 1626 action recommendations to address root causes of impacts regarding the merger based upon the survey data in the database. The visual summaries 600, 1100, or 1200 may be arranged in a pictorial representation 700 of an interrelationship between the organizational aspects 402 that may be interactively selectable by a user.
摘要翻译：披露用于并购分析的装置，系统和方法。调查模块202可以提供关于组织方面402的调查，包括主观方面和客观方面。数据库模块204可以收集关于将候选者合并到调查数据的数据库中的第一公司和第二公司的关于调查的答复。报告模块206可以显示1612,1624或1634图形，其呈现每个组织方面402的调查数据的视觉摘要600,1100或1200.推荐模块108可以生成1626个动作建议以解决影响的根本原因关于基于数据库中的调查数据的合并。视觉摘要600,1100或1200可以布置在可由用户交互地选择的组织方面402之间的相互关系的图示表示700中。

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