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1. 发明申请

WO0160433A9 CATHETER HANDLE FOR CONTROLLING THE ADVANCEMENT OF A GUIDE WIRE 审中-公开
标题翻译：用于控制指导线优化的电缆手柄
公开(公告)号：WO0160433A9
公开(公告)日：2002-10-31
申请号：PCT/US0104808
申请日：2001-02-15
申请人： INTRALUMINAL THERAPEUTICS INC , WINSTON THOMAS R , NEET JOHN M , WHITE JEFFREY , WARDLE JOHN , CUETO DIEGO D
发明人： WINSTON THOMAS R , NEET JOHN M , WHITE JEFFREY , WARDLE JOHN , CUETO DIEGO D
IPC分类号： A61M20060101 , A61M5/178 , A61M25/01
CPC分类号： A61M25/09041
摘要： A catheter handle (100) for controlling the advancement of a guide wire through a catheter is described. The catheter handle (100) has a distal end to which is coupled a luer lock element (132) and a proximal end to which a control knob is coupled. The luer lock element (132) is adaptable to allow coupling of the catheter handle to any commonly available commercial catheter. The control knob is coupled to a guide wire advancement mechanism (172). Movement of the control knob (120) is translated by the advancement mechanism to advancement or braking of the guide wire.
摘要翻译：描述了用于控制导丝通过导管的前进的导管手柄（100）。导管手柄（100）具有一个远端，一个鲁尔锁定元件（132）和一个控制旋钮相连接的近端连接到该远端上。鲁尔锁定元件（132）适于允许导管手柄与任何通常可用的商业导管的联接。控制旋钮连接到导丝推进机构（172）。控制旋钮（120）的移动由推进机构平移以引导导线的前进或制动。

2. 发明申请

WO0154762A9 CATHETER FOR CONTROLLING THE ADVANCEMENT OF A GUIDE WIRE 审中-公开
标题翻译：用于控制指导线优化的导管
公开(公告)号：WO0154762A9
公开(公告)日：2002-10-17
申请号：PCT/US0102847
申请日：2001-01-29
申请人： INTRALUMINAL THERAPEUTICS INC , NEET JOHN M , WINSTON THOMAS R , WHITE JEFFREY , WARDLE JOHN , CUETO DIEGO D
发明人： NEET JOHN M , WINSTON THOMAS R , WHITE JEFFREY , WARDLE JOHN , CUETO DIEGO D
IPC分类号： A61M25/01 , A61M25/09
CPC分类号： A61M25/09041 , A61M25/0147
摘要： A catheter for controlling the advancement of a guide wire includes a catheter body having a central lumen, a first side lumen and a second side lumen. A pair of opposing control wires extend the length of the catheter body through the side lumens. The catheter body includes a proximal portion coupled to a less rigid distal portion. A control handle coupled to the proximal ends of the control wires produces opposing motion of the control wires along the length of the catheter body, causing the distal portion of the catheter body to deflect relative to the proximal portion of the catheter body, thus directing the guide wire. In one embodiment, the control handle includes a guide wire advancement mechanism for controlling the advancement of the guide wire through the catheter.
摘要翻译：用于控制引导线的前进的导管包括具有中心腔，第一侧腔和第二侧腔的导管主体。一对相对的控制线将导管主体的长度延伸通过侧腔。导管主体包括联接到较不刚性的远端部分的近端部分。耦合到控制线的近端的控制手柄产生控制线沿着导管主体的长度的相对运动，导致导管主体的远端部分相对于导管主体的近端部分偏转，从而将导丝。在一个实施例中，控制手柄包括用于控制导丝通过导管的前进的引导丝推进机构。

3. 发明申请

WO0041611A3 SYSTEM AND METHOD FOR CONTROLLING TISSUE ABLATION 审中-公开
标题翻译：控制组织脱落的系统和方法
公开(公告)号：WO0041611A3
公开(公告)日：2000-11-30
申请号：PCT/US0000460
申请日：2000-01-07
申请人： INTRALUMINAL THERAPEUTICS INC , WINSTON THOMAS R , NEET JOHN M
发明人： WINSTON THOMAS R , NEET JOHN M
IPC分类号： G01N21/65 , A61B1/00 , A61B17/00 , A61B17/22 , A61B17/32 , A61B18/00 , A61B18/12 , A61B18/18 , A61B18/20 , G01N21/35 , G01N21/45 , A61N5/06
CPC分类号： A61B18/1206 , A61B17/00 , A61B18/00 , A61B2017/00061
摘要： A control system (100), and method for controlling tissue ablation, uses an optical time domain reflectometer data to differentiate abnormal tissue from normal tissue; and to control ablation of abnormal tissue by controlling a tissue ablative apparatus (108). Using data provided by an interferometric apparatus (106), the control system (100) provides control signals to the tissue ablative apparatus (100), controlling activation of the tissue ablation apparatus (108) so that normal tissue is left untreated while abnormal tissue is ablated.
摘要翻译：控制系统（100）和控制组织消融的方法使用光学时域反射仪数据来区分异常组织与正常组织; 并通过控制组织消融装置来控制异常组织的消融（108）。使用由干涉测量设备（106）提供的数据，控制系统（100）向组织消融设备（100）提供控制信号，控制组织消融设备（108）的激活，使得正常组织不被处理而异常组织消融。

4. 发明申请

WO0009196A9 EXPANDABLE LASER CATHETER 审中-公开
标题翻译：可扩展激光导管
公开(公告)号：WO0009196A9
公开(公告)日：2000-06-08
申请号：PCT/US9917317
申请日：1999-07-29
申请人： INTRALUMINAL THERAPEUTICS INC , WINSTON THOMAS R , NEET JOHN M
发明人： WINSTON THOMAS R , NEET JOHN M
IPC分类号： A61B17/22 , A61B18/22 , A61B18/24 , A61F2/958 , A61M25/00 , A61M29/02
CPC分类号： A61B18/245 , A61B18/24 , A61B2017/22051 , A61B2018/00214 , A61B2018/00577 , A61B2018/2211 , A61B2018/2238 , A61B2018/2266 , A61B2018/2288 , A61M25/0021 , A61M25/0023 , A61M25/1002 , A61M29/02 , A61M2025/0024 , A61M2025/1004
摘要： Expandable laser catheters (10) for utilizing laser energy to remove obstructions (36) from body passages (34) are described. In one embodiment, the laser catheter includes a shaftway (12) having a distal end (18) including a flexible portion (20) configured in a series of radial folds. Multiple optical fibers (30), configured to transmit laser energy, extend along the shaftway and are attached to the flexible portion. An inflatable, ring-shaped balloon (22) is attached to the catheter (10) within the flexible portion (20). In use, the catheter (10) is inserted into a body passage (34) such as an artery, and advanced until the distal end (18) is adjacent to an obstruction. The balloon (22) is inflated to expand the flexible portion (20) and to bring the optical fibers (30) nearer the inner wall of the body passage. Laser energy is directed by the optical fibers (30) toward targeted regions of the obstruction (36). As the catheter is advanced and the process repeated, a core (50) is formed from the obstruction (36) and contained within the flexible portion (20). The flexible portion (20) is then contracted to hold the core (50), and the core (50) is removed from the body passage (34) by withdrawing the catheter (10).
摘要翻译：描述了用于利用激光能量去除主体通道（34）的障碍物（36）的可扩展激光导管（10）。在一个实施例中，激光导管包括具有远端（18）的轴（12），该远端包括构造成一系列径向折叠的柔性部分（20）。被配置为传递激光能量的多个光纤（30）沿着轴线延伸并附接到柔性部分。可膨胀的环形气囊（22）在柔性部分（20）内附接到导管（10）。在使用中，将导管（10）插入诸如动脉的体通道（34）中，并且前进直到远端（18）与障碍物相邻。气球膨胀以膨胀柔性部分（20）并使光纤（30）靠近身体通道的内壁。激光能量被光纤（30）引向障碍物（36）的目标区域。当导管前进并且重复该过程时，从障碍物（36）形成并包含在柔性部分（20）内的芯（50）。然后使柔性部分（20）收缩以保持芯部（50），并且通过抽出导管（10）将芯部（50）从主体通道（34）移除。

5. 发明申请

WO0023125A3 CATHETER FOR LASER TREATMENT OF ATHEROSCLEROTIC PLAQUE AND OTHER TISSUE ABNORMALITIES 审中-公开
标题翻译：激光治疗动脉粥样硬化斑块及其他组织异常的导管
公开(公告)号：WO0023125A3
公开(公告)日：2000-11-30
申请号：PCT/US9924099
申请日：1999-10-18
申请人： INTRALUMINAL THERAPEUTICS INC
发明人： WINSTON THOMAS R , NEET JOHN M
IPC分类号： A61B8/08 , A61B8/12 , A61B18/24 , A61B19/00 , A61B1/04
CPC分类号： A61B8/12 , A61B5/02007 , A61B8/0833 , A61B8/0858 , A61B8/445 , A61B8/4461 , A61B18/245 , A61B2090/3784
摘要： A medical catheter (10) for treating atherosclerotic plaque and other abnormalities includes optical fibers (30) for applying laser energy (100) to the plaque and an ultrasonic transducer system (32, 34) for sensing the location and configuration of the plaque. The optical fibers (30) and electrical wiring for the transducers (32, 34) extend through a probe (28) which is rotatable inside of the catheter tube (12) to provide universal directional control of the fibers (30) and transducers (32, 34). A reflective system includes a curved reflector (38) in the probe (28) which can be axially adjusted to vary the direction of the ultrasonic signals. Alternative forms of the invention include different reflector schemes, an angled ultrasonic transducer (110) having a conical signal output that varies with frequency, and various different systems for rotating the transducers and fibers.
摘要翻译：用于治疗动脉粥样硬化斑块和其他异常的医疗导管（10）包括用于将激光能量（100）施加至牙斑的光纤（30）和用于感测牙斑的位置和构造的超声波换能器系统（32,34）。用于换能器（32,34）的光纤（30）和电线延伸穿过可在导管（12）内部旋转的探针（28），以提供纤维（30）和换能器（32）的通用方向控制，34）。反射系统包括探头（28）中的弯曲反射器（38），其可以被轴向调节以改变超声波信号的方向。本发明的可选形式包括不同的反射器方案，具有随频率变化的圆锥形信号输出的成角度的超声波换能器（110），以及用于旋转换能器和光纤的各种不同的系统。

6. 发明申请

WO2004060434A2 DEFLECTING CATHETER 审中-公开
标题翻译：偏转导管
公开(公告)号：WO2004060434A2
公开(公告)日：2004-07-22
申请号：PCT/US0334710
申请日：2003-10-31
申请人： INTRALUMINAL THERAPEUTICS INC
发明人： JOHANSEN JERALD A , YEE CARL E , NEET JOHN M
IPC分类号： A61M25/00 , A61M25/01 , A61M29/02 , A61M
CPC分类号： A61M29/02 , A61M25/0097 , A61M25/0155
摘要： A catheter includes a distal end, a proximal end, an outer tube extending from the distal end to the proximal end, and an inner tube extending through the outer tube. The distal end including a corrugated section attached to an end of the inner tube and an asymmetric balloon attached to the outer tube and configured to deflect the distal end of the catheter.
摘要翻译：导管包括远端，近端，从远端延伸到近端的外管，以及延伸穿过外管的内管。远端包括附接到内管的端部的波纹部分和附接到外管并且构造成使导管的远端偏转的不对称气囊。

7. 发明申请

WO9314689A3 MEDICAL CATHETER USING ULTRASOUND MAPPING WITH EXTERNAL TRANSDUCERS 审中-公开
标题翻译：医用导管使用超声波映射与外部传感器
公开(公告)号：WO9314689A3
公开(公告)日：1993-10-14
申请号：PCT/US9300314
申请日：1993-01-14
申请人： WINSTON THOMAS R
发明人： WINSTON THOMAS R , NEET JOHN M
IPC分类号： A61B8/12 , A61B17/00 , A61B17/22 , A61B17/32 , A61B18/00 , A61B18/22 , A61B18/24 , A61B1/04
CPC分类号： A61B8/12 , A61B8/445 , A61B17/22 , A61B18/245 , A61B2017/00106 , A61B2017/22017 , A61B2017/22051 , A61B2017/320004 , A61B2018/1861 , A61B2018/2238
摘要： A medical catheter (10) for treating atherosclerotic plaque and other abnormalities includes for an ultrasonic transducer (34) system which makes use of optical fibers (30) for transmitting ultrasonic signals through the catheter (10). The optical fibers (30) extend through a probe (28) which is rotatable inside of the catheter tube (12) to permit the ultrasonic system to sweep the entire area of the catheter tip (30a). In an alternative form of the invention, multiple transducers (164) are carried on disks (162) that rotate with the probe (28), and slip ring electrical contacts (154) establish electrical connections (156) with the rotating parts.

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