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1. 发明申请

WO2010134753A3 METHOD AND SYSTEM FOR EDITING DOCUMENT TO WHICH ADDITIONAL EXPLANATION OR LINK-RELATED METADATA CAN BE FREELY INPUTTED IN COOPERATION WITH INTERNET SEARCH 审中-公开
标题翻译：用于编辑文档的方法和系统，其中附加说明或链接相关元数据可以被自由地与互联网搜索合作
公开(公告)号：WO2010134753A3
公开(公告)日：2011-03-24
申请号：PCT/KR2010003159
申请日：2010-05-19
申请人： INEK CO LTD , CHOI HYUN JUNG , KIM DONG BUM , YUN SANG JIN , KIM SU JIN , LEE MUN HEE , LEE SEOK HEUI
发明人： CHOI HYUN JUNG , KIM DONG BUM , YUN SANG JIN , KIM SU JIN , LEE MUN HEE , LEE SEOK HEUI
IPC分类号： G06F17/24 , G06F17/21
CPC分类号： G06F17/241 , G06F17/30861
摘要： The present invention relates to a document editing method and system, in which when a user edits a web document such as a post on the Internet, the user can make a block around a specific word or sentence and multi-set and manage any related additional explanation, URL in result of the Internet search or a combination thereof so that detailed information on a corresponding block according to the Internet user's choice can easily be provided. In the document editing method according to the present invention, a document editing means is provided, so when the document editing means edits a document, a certain part of the document is inserted into a block and additional explanation or an Internet address is multi-set, stored and managed as the detailed information that is linked to the corresponding block.
摘要翻译：本发明涉及一种文件编辑方法和系统，其中当用户在因特网上编辑诸如帖子的web文档时，用户可以围绕特定的单词或句子进行阻止并且多组并且管理任何相关的附加解释，因特网搜索结果中的URL或其组合，使得可以容易地提供根据因特网用户选择的相应块的详细信息。在根据本发明的文档编辑方法中，提供了一种文档编辑装置，因此当文档编辑装置编辑文档时，文档的某一部分被插入到块中，并且附加说明或因特网地址被多重设置，作为链接到相应块的详细信息进行存储和管理。

2. 发明申请

WO2012128577A3 METHOD FOR PERFORMANCE ANALYSIS AND SCREENING OF SEPTICAEMIA PROTEIN THERAPEUTIC AGENTS 审中-公开
标题翻译：分离蛋白质治疗药物的性能分析和筛选方法
公开(公告)号：WO2012128577A3
公开(公告)日：2013-01-24
申请号：PCT/KR2012002091
申请日：2012-03-22
申请人： KOREA RES INST OF BIOSCIENCE , KOREA ADVANCED INST SCI & TECH , LEE SEUNG GOO , KIM HAK SUNG , KIM YU JUNG , LEE SANG CHUL , HAN JI EUN , KIM SU JIN , SOHN JUNG HOON , HA JAE SEOK
发明人： LEE SEUNG GOO , KIM HAK SUNG , KIM YU JUNG , LEE SANG CHUL , HAN JI EUN , KIM SU JIN , SOHN JUNG HOON , HA JAE SEOK
IPC分类号： C12Q1/02 , C12N15/63 , G01N33/15 , G01N33/53 , G01N33/68
CPC分类号： C07K14/195 , C07K14/46 , C07K14/461 , C07K14/705 , C07K2319/35 , C07K2319/70 , C12N15/70 , C12Q1/6897 , G01N33/5023 , G06F19/16
摘要： The present invention relates to the construction of an assay system for analysing the performance of LRR (leucine rich repeat) proteins, that are constituted by the repeat combination of LRR modules, as septicaemia-inhibiting protein therapeutic agents, and for screening protein therapeutic agents that exhibit an outstanding inhibiting performance from a sequence variation library. More specifically, the present invention relates to: a performance analysis method or screening method for septicaemia protein therapeutic agents, comprising the step of adding purified MD-2 protein to an assay system using a cell line in which an LPS signal transmission receptor is expressed on the surface; a performance analysis method or screening method for septicaemia protein therapeutic agents, comprising the step of adding a purified foreign MD-2 protein to a THP-1 cell line; the cell line for performance analysis or for screening; and a kit for septicaemia therapeutic agent screening or performance analysis, comprising the cell line and purified foreign MD-2.
摘要翻译：本发明涉及用于分析LRR（富含亮氨酸重复）蛋白质的性能的测定系统的构建，其由LRR模块的重复组合构成，作为败血病抑制蛋白质治疗剂，并用于筛选蛋白质治疗剂，从序列变异库显示出优异的抑制性能。更具体地，本发明涉及：败血病蛋白治疗剂的性能分析方法或筛选方法，包括将纯化的MD-2蛋白加入到使用其中表达LPS信号传递受体的细胞系的测定系统的步骤表面用于败血病蛋白治疗剂的性能分析方法或筛选方法，包括将纯化的外源MD-2蛋白加入到THP-1细胞系中的步骤; 用于性能分析或筛选的细胞系; 以及用于败血症治疗剂筛选或性能分析的试剂盒，其包含细胞系和纯化的外源MD-2。

3. 发明申请

WO2012128502A9 COMPOSITION FOR PROMOTING VASCULOGENESIS COMPRISING PAUF 审中-公开
标题翻译：用于促进包含PAUF的血管生成的组合物
公开(公告)号：WO2012128502A9
公开(公告)日：2013-01-03
申请号：PCT/KR2012001858
申请日：2012-03-14
申请人： KOREA RES INST OF BIOSCIENCE , KOH SANG SEOK , KIM SU JIN , MIN JEONG KI
发明人： KOH SANG SEOK , KIM SU JIN , MIN JEONG KI
IPC分类号： A61K38/17 , A61P1/04 , A61P9/00 , C07K16/18
CPC分类号： A61K38/1709
摘要： The present invention relates to a composition for promoting vasculogenesis comprising PAUF, and more specifically relates to, by way of example, a pharmaceutical composition for chronic ulceration and protracted injury therapy and/or the treatment of cardiovascular disease using PAUF. The PAUF protein of the present invention exhibits an effect whereby the process of vasculogenesis can be induced by stimulating and thereby promoting growth, motility and differentiation of vascular endothelial cells. In other words, the PAUF protein having a novel function as a vasculogenesis promoting factor can be expected to be useful in the development of therapeutic agents for various diseases where vasculogenesis is required.
摘要翻译：本发明涉及用于促进血管发生的组合物，其包含PAUF，更具体地涉及例如用于慢性溃疡和延长性损伤治疗的药物组合物和/或使用PAUF治疗心血管疾病。本发明的PAUF蛋白质具有通过刺激并促进血管内皮细胞的生长，运动和分化来诱导血管发生过程的作用。换句话说，具有作为血管发生促进因子的新功能的PAUF蛋白质可以用于开发需要血管发生的各种疾病的治疗剂。

4. 发明申请

WO2012128502A2 COMPOSITION FOR PROMOTING VASCULOGENESIS COMPRISING PAUF 审中-公开
标题翻译：用于促进包含PAUF的血管生成的组合物
公开(公告)号：WO2012128502A2
公开(公告)日：2012-09-27
申请号：PCT/KR2012001858
申请日：2012-03-14
申请人： KOREA RES INST OF BIOSCIENCE , KOH SANG SEOK , KIM SU JIN , MIN JEONG KI
发明人： KOH SANG SEOK , KIM SU JIN , MIN JEONG KI
IPC分类号： A61K38/17 , A61P1/04 , A61P9/00 , C07K16/18
CPC分类号： A61K38/1709
摘要： The present invention relates to a composition for promoting vasculogenesis comprising PAUF, and more specifically relates to, by way of example, a pharmaceutical composition for chronic ulceration and protracted injury therapy and/or the treatment of cardiovascular disease using PAUF. The PAUF protein of the present invention exhibits an effect whereby the process of vasculogenesis can be induced by stimulating and thereby promoting growth, motility and differentiation of vascular endothelial cells. In other words, the PAUF protein having a novel function as a vasculogenesis promoting factor can be expected to be useful in the development of therapeutic agents for various diseases where vasculogenesis is required.
摘要翻译：本发明涉及用于促进血管发生的组合物，其包含PAUF，更具体地涉及例如用于慢性溃疡和延长性损伤治疗的药物组合物和/或使用PAUF治疗心血管疾病。本发明的PAUF蛋白质具有通过刺激并促进血管内皮细胞的生长，运动和分化来诱导血管发生过程的作用。换句话说，具有作为血管发生促进因子的新功能的PAUF蛋白质可以用于开发需要血管发生的各种疾病的治疗剂。

5. 发明申请

WO2012050320A3 GAME SERVER, SYSTEM AND METHOD FOR ENABLING DONATION BY GROWING ITEMS IN GAME 审中-公开
标题翻译：游戏服务器，系统和方法通过在游戏中增加项目来实现捐赠
公开(公告)号：WO2012050320A3
公开(公告)日：2012-05-31
申请号：PCT/KR2011007386
申请日：2011-10-06
申请人： NEOWIZ GAMES CO LTD , LEE JIN WOONG , NAM HAN SAN , CHOI KEON BIN , KIM SU JIN , KO HYE YOUNG
发明人： LEE JIN WOONG , NAM HAN SAN , CHOI KEON BIN , KIM SU JIN , KO HYE YOUNG
IPC分类号： G06Q50/00
CPC分类号： A63F13/85 , A63F13/69 , A63F13/79 , A63F13/825 , A63F2300/57
摘要： The present invention relates to a game server, system and method for enabling donations by growing items in a game, and more particularly, to a game server, system and method for enabling donation by growing items in a game wherein when a game player has grown an item to create a resulting item, said game player is enabled to donate the resulting item, and a game provider estimates the value of the result as an actual object and donates according to company policy when receiving a donation request from the game player. To this end, the game server for enabling donation by growing items of a game according to the present invention comprises: a level management unit which manages a character or the level of an item being grown in the game; a quest unit which provides a quest for changing the character or the level of the item being grown and for gaining and losing items; a result change unit which changes a final resulting item, which is obtained by upgrading the level of the item being grown, to an exchange item; and a donation request reception unit which updates a donation application database when receiving a donation request signal using the exchange item from a user terminal. Accordingly, the present invention stimulates the game players' enjoyment and interest in the act of donating through games, thereby making it possible to establish a more active and enjoyable culture of donation.
摘要翻译：游戏服务器，系统和方法技术领域本发明涉及一种用于通过在游戏中增长物品来进行捐赠的游戏服务器，系统和方法，并且更具体地涉及一种用于通过在游戏中增长物品来进行捐赠的游戏服务器，系统和方法，其中当游戏者所述游戏者能够捐赠所得到的物品，并且游戏提供者在接收到来自游戏玩家的捐赠请求时根据公司策略捐赠物品作为实际物品并且捐赠。为此，根据本发明的用于通过增长游戏项目进行捐赠的游戏服务器包括：等级管理单元，其管理在游戏中正在生长的物品的角色或等级; 一个任务单位，提供改变正在生长的物品的角色或等级以及获得和失去物品的任务; 结果改变单元，其将通过升级正在生长的物品的等级而获得的最终结果物品改变为交换物品; 以及捐款请求接收单元，当从用户终端使用交换项目接收捐赠请求信号时，更新捐赠申请数据库。因此，本发明刺激游戏玩家通过游戏进行捐赠的乐趣和兴趣，从而可以建立更积极和愉快的捐赠文化。

6. 发明申请

WO2010036031A3 PAUF-SPECIFIC HUMAN MONOCLONAL ANTIBODY, PHARMACEUTICAL COMPOSITION FOR TREATING CANCER COMPRISING THE SAME AND METHOD FOR DETECTING CANCER USING THE SAME 审中-公开
标题翻译： PAUF特异性人单核抗体，用于治疗包含其的癌症的药物组合物和使用其检测癌症的方法
公开(公告)号：WO2010036031A3
公开(公告)日：2010-06-24
申请号：PCT/KR2009005437
申请日：2009-09-23
申请人： KOREA RES INST OF BIOSCIENCE , KOH SANG SEOK , LEE YANG SOON , SOHN MI JIN , KIM SU JIN , YOO KYUNG SOOK , PARK EUN HYE
发明人： KOH SANG SEOK , LEE YANG SOON , SOHN MI JIN , KIM SU JIN , YOO KYUNG SOOK , PARK EUN HYE
IPC分类号： C07K16/18
CPC分类号： C07K16/303 , A61K2039/505 , C07K2317/21 , C07K2317/73
摘要： Disclosed are a PAUF protein associated with the onset of cancer, a human monoclonal antibody specific to the PAUF protein, and a nucleic acid molecule coding for the PAUF protein, and uses thereof. Closely correlated with the onset of cancer, the PAUF protein or the PAUF nucleic acid molecule can be used as a diagnostic marker or a therapeutic target. In addition, having the ability to bind specifically to PAUF presented on the surface of various cancer cells including pancreatic cancer cells, the anti-PAUF antibody or its functional fragment allows the diagnosis of cancer in the early stages thereof and can inhibit the growth, invasion or migration of cancer cells by inducing the cells to undergo apoptosis, and thus are useful in the diagnosis and treatment of cancer.
摘要翻译：公开了与癌症发作相关的PAUF蛋白质，对PAUF蛋白质特异的人单克隆抗体，以及编码PAUF蛋白质的核酸分子及其用途。 PAUF蛋白或PAUF核酸分子与癌症发病密切相关，可用作诊断标记物或治疗靶点。此外，具有特异性结合PAUF的能力，其包括胰腺癌细胞在内的各种癌细胞的表面，抗PAUF抗体或其功能片段能够在早期诊断癌症，并可抑制生长，侵袭或通过诱导细胞进行细胞凋亡来移植癌细胞，因此可用于诊断和治疗癌症。

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