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1. 发明申请

WO2011162910A1 PHOTODYNAMIC BONE STABILIZATION AND DRUG DELIVERY SYSTEMS 审中-公开
标题翻译：光稳定性骨骼稳定和药物输送系统
公开(公告)号：WO2011162910A1
公开(公告)日：2011-12-29
申请号：PCT/US2011/038389
申请日：2011-05-27
申请人： ILLUMINOSS MEDICAL, INC. , RABINER, Robert, A. , RADER, Richard, Scott
发明人： RABINER, Robert, A. , RADER, Richard, Scott
IPC分类号： A61N1/30
CPC分类号： A61M25/10 , A61B17/7097 , A61B17/7098 , A61B17/7275 , A61B17/8836 , A61B17/8855 , A61B2017/00411 , A61M25/1011 , A61M2025/1013 , A61M2025/105 , A61M2025/1075 , A61M2205/0244 , A61N5/062 , A61N2005/0612 , A61N2005/063
摘要： Photodynamic bone stabilization and drug delivery systems include an insertion catheter (101) having an inner void (110) for passing at least one light-sensitive liquid, and an inner lumen (120); an expandable portion (400) releasably engaging a distal end (114) of the insertion catheter (101), wherein the expandable portion (400) comprises an inner expandable portion (410) in communication with the inner lumen (110) of the insertion catheter (101) and sufficiently designed to maintain a light-sensitive liquid therein; and an outer expandable portion (450), surrounding the inner expandable portion (410), sufficiently designed to house and release at least one additive from the outer expandable portion (450) in an outward direction from the inner expandable portion (410); and a light-conducting fiber sized to pass through the inner lumen (110) of the insertion catheter (101) and into the inner expandable portion (410) for delivering light energy to the light-sensitive liquid.
摘要翻译：光动力学骨骼稳定和药物递送系统包括具有用于使至少一种感光液体通过的内部空隙（110）和内腔（120）的插入导管（101）。可释放地接合所述插入导管（101）的远端（114）的可膨胀部分（400），其中所述可扩张部分（400）包括与所述插入导管（101）的内腔（110）连通的内部可扩张部分（410）（101）并且被充分设计成在其中保持感光液体; 以及围绕所述内部可膨胀部分（410）的外部可膨胀部分（450），所述外部可膨胀部分（450）被充分地设计成在从所述内部可膨胀部分（410）向外的方向上容纳和释放来自所述外部可扩张部分（450）的至少一种添加剂。以及尺寸适于穿过插入导管（101）的内腔（110）并进入内部可膨胀部分（410）的导光纤维，用于将光能传递给感光液体。

2. 发明申请

WO2009026070A1 APPARATUS AND METHODS FOR ATTACHING SOFT TISSUE TO BONE 审中-公开
标题翻译：用于将软组织装入骨的装置和方法
公开(公告)号：WO2009026070A1
公开(公告)日：2009-02-26
申请号：PCT/US2008/073016
申请日：2008-08-13
申请人： ILLUMINOSS MEDICAL, INC. , RABINER, Robert, A. , GREEN, Andrew
发明人： RABINER, Robert, A. , GREEN, Andrew
IPC分类号： A61B17/04
CPC分类号： A61B17/0401 , A61B2017/0409 , A61B2017/0424 , A61B2017/0432 , A61B2017/0445
摘要： Suture anchors (100) and methods for using the suture anchors (100) for attaching soft tissue, such as ligaments, tendons, and muscles, to bone are disclosed herein. A suture anchor (100) for attaching soft tissue to bone includes a catheter (130) having an elongated shaft with a proximal end, a distal end, and a longitudinal axis therebetween, wherein the catheter (130) has at least one inner lumen capable of allowing a light curable adhesive to pass therethrough; a balloon portion engaging the distal end of the catheter (130), wherein the balloon portion (136) expands from a deflated state to an inflated state when a light curable adhesive is delivered to the balloon portion (136); and at least one suture material (150) for passing through soft tissue to attach the soft tissue to a bone.
摘要翻译：本文公开了缝合锚（100）和使用缝合锚（100）将软组织（例如韧带，肌腱和肌肉）附着于骨的方法。用于将软组织附接到骨头的缝合锚（100）包括具有细长轴的导管（130），所述细长轴具有近端，远端和在它们之间的纵向轴线，其中所述导管（130）具有至少一个内腔，允许光固化粘合剂通过; 接合所述导管（130）的远端的气囊部分，其中当所述可光固化的粘合剂被输送到所述气囊部分（136）时，所述球囊部分（136）从放气状态膨胀到膨胀状态; 和用于穿过软组织以将软组织附着到骨骼上的至少一个缝线材料（150）。

3. 发明申请

WO2017079613A1 SYSTEMS AND METHODS FOR ANTI-MICROBIAL EFFECT FOR BONES 审中-公开
标题翻译：用于骨骼的抗微生物效应的系统和方法
公开(公告)号：WO2017079613A1
公开(公告)日：2017-05-11
申请号：PCT/US2016/060603
申请日：2016-11-04
申请人： ILLUMINOSS MEDICAL, INC. , RABINER, Robert, A. , RABINER, Daniel, E. , DIPOTO, Gene, P. , SHANAHAN, Augustus, C. , SHULER, Franklin, D.
发明人： RABINER, Robert, A. , RABINER, Daniel, E. , DIPOTO, Gene, P. , SHANAHAN, Augustus, C. , SHULER, Franklin, D.
IPC分类号： A61K33/24 , A61F13/00 , A61K33/38
CPC分类号： A61N5/0624 , A61M25/10 , A61M2210/02 , A61N5/0601 , A61N5/062 , A61N2005/063
摘要： Systems and methods for restructure and stabilization of bones that provide an antimicrobial effect are disclosed herein. A device includes a delivery catheter having an inner void for passing at least one light sensitive liquid, and an inner lumen; an expandable member releasably engaging the distal end of the delivery catheter; at least one channel positioned in the expandable member; and a light conducting fiber sized to pass through the inner lumen of the delivery catheter and into the expandable member, wherein, when the light conducting fiber is in the at least one channel, the light conducting fiber is able to disperse light energy to provide an anti-microbial effect. When the light conducting fiber is in the expandable member, the light conducting fiber is able to disperse the light energy to initiate hardening of the light sensitive liquid within the expandable member to form a photodynamic implant.
摘要翻译：本文公开了用于重构和稳定提供抗微生物作用的骨的系统和方法。一种装置包括输送导管和内腔;所述输送导管具有用于使至少一种光敏液体通过的内部空隙; 可扩张构件，其可释放地接合输送导管的远端; 至少一个通道位于可膨胀构件中; 以及光传导纤维，其尺寸设定为穿过传送导管的内腔并进入可膨胀构件，其中当光导纤维处于至少一个通道中时，光传导纤维能够分散光能以提供抗微生物作用。当光导纤维处于可膨胀构件中时，光导纤维能够分散光能以引发可膨胀构件内的光敏液体的硬化以形成光动力植入物。

4. 发明申请

WO2008063265A1 SYSTEMS AND METHODS FOR INTERNAL BONE FIXATION 审中-公开
标题翻译：用于内固定的系统和方法
公开(公告)号：WO2008063265A1
公开(公告)日：2008-05-29
申请号：PCT/US2007/020402
申请日：2007-09-20
申请人： ILLUMINOSS MEDICAL, INC. , RABINER, Robert, A. , DREW, Mark, A.
发明人： RABINER, Robert, A. , DREW, Mark, A.
IPC分类号： A61B17/56 , A61K6/08 , A61F2/28
CPC分类号： A61B17/7097 , A61B17/68 , A61B17/7275 , A61B17/7291 , A61B17/8836 , A61B2017/00557
摘要： Internal bone fixation devices and methods for using the devices for repairing a weakened or fractured bone are disclosed herein. A device for use in repairing a fractured bone includes a delivery catheter having an elongated shaft with a proximal end, a distal end, and a longitudinal axis therebetween, wherein the delivery catheter has an inner void for passage of at least one reinforcing material and an inner lumen for passage of a light source; a conformable member releasably engaging the distal end of the delivery catheter, wherein the conformable member moves from a deflated state to an inflated state when the at least one reinforcing material is delivered to the conformable member; and an adapter releasably engaging the proximal end of the delivery catheter for receiving the light source and the at least one reinforcing material.
摘要翻译：本文公开了内部骨固定装置和使用该装置来修复弱化骨或骨折骨的方法。用于修复骨折骨的装置包括具有细长轴的输送导管，其具有近端，远端和其间的纵向轴线，其中输送导管具有用于至少一个增强材料通过的内部空间和用于通过光源的内腔; 可释放地接合输送导管的远端的适形构件，其中当所述至少一个增强材料被递送到所述适形构件时，所述适形构件从放气状态移动到膨胀状态; 以及可释放地接合所述输送导管的近端的适配器，用于接收所述光源和所述至少一种增强材料。

5. 发明申请

WO2013013069A1 COMBINATION PHOTODYNAMIC DEVICES 审中-公开
标题翻译：组合光电装置
公开(公告)号：WO2013013069A1
公开(公告)日：2013-01-24
申请号：PCT/US2012/047444
申请日：2012-07-19
申请人： ILLUMINOSS MEDICAL, INC. , RABINER, Robert, A. , RADER, Richard, Scott
发明人： RABINER, Robert, A. , RADER, Richard, Scott
IPC分类号： A61B17/68
CPC分类号： A61F2/30724 , A61B17/7097 , A61B17/7233 , A61B17/7258 , A61B17/7275 , A61B17/7283 , A61F2/30749 , A61F2/3804 , A61F2002/30934 , A61F2002/4631 , A61N5/062 , A61N2005/0612
摘要： Combination photodynamic devices (100) for repair and stabilization of a fractured or a weakened bone are disclosed herein. In an embodiment, a combination photodynamic device (100) includes a load bearing member (115) and one or more conformable members (170) connected to the load bearing member (115), the conformable member (170) expandable from a deflated state to an inflated state. The load bearing member (115) is designed to reside inside a cavity of fractured or weakened bone and act as internal bone fixation and stabilization device. The conformable member (170) is designed to anchor the load bearing member (115) inside a bone cavity, transform the load bearing member (115) from a flexible state to a rigid state, contribute to fixating and stabilizing a fractured or a weakened bone, and provide longitudinal and rotational stability to a fractured or a weakened bone during the healing process or combinations thereof.
摘要翻译：本文公开了用于修复和稳定骨折的骨组织光动力装置（100）。在一个实施例中，组合光动力装置（100）包括承载构件（115）和连接到承载构件（115）的一个或多个适形构件（170），适形构件（170）可从放气状态扩展到充气状态。承载构件（115）被设计成位于骨折或骨骼骨的腔内，并且用作内骨固定和稳定装置。适形构件（170）设计成将承载构件（115）锚固在骨腔内，将承载构件（115）从柔性状态转变为刚性状态，有助于固定和稳定骨折或骨化并且在愈合过程或其组合期间向断裂或弱化骨提供纵向和旋转稳定性。

6. 发明申请

WO2012088432A1 SYSTEMS AND METHODS FOR TREATING CONDITIONS AND DISEASES OF THE SPINE 审中-公开
标题翻译：用于治疗脊椎病症和疾病的系统和方法
公开(公告)号：WO2012088432A1
公开(公告)日：2012-06-28
申请号：PCT/US2011/066871
申请日：2011-12-22
申请人： ILLUMINOSS MEDICAL, INC. , RABINER, Robert, A. , DIPOTO, Gene, P.
发明人： RABINER, Robert, A. , DIPOTO, Gene, P.
IPC分类号： A61B17/66
CPC分类号： A61B17/7097 , A61B17/8802 , A61B17/8805 , A61B17/8833 , A61B17/8836 , A61B17/885 , A61B17/8852 , A61B17/8855 , A61B2090/306 , A61F2/441 , A61F2002/30581 , A61F2002/30583 , A61F2002/30971 , A61F2002/4495
摘要： Systems and methods for treating conditions and diseases of the spine are disclosed herein. A device includes a balloon catheter (110) comprising at least one inner lumen incorporated within an elongated shaft (101); a distal end (104) having an inner balloon positioned inside and completely surrounded by an outer balloon; and a proximal end (102) having an adapter for passage of at least one of an inflation fluid or a medical instrument; and an optical fiber (106) comprising an outer diameter sized to pass through the inner lumen of the elongated shaft (101); a nonlinear light-emitting portion (158) of a given length, wherein a portion of a cladding material from the nonlinear light-emitting portion (158) has been removed so that light energy may be emitted along the length of the nonlinear light-emitting portion (158); and a linear elongated portion (148) for guiding light towards the nonlinear light-emitting portion (158).
摘要翻译：本文公开了用于治疗脊柱病症和疾病的系统和方法。装置包括气囊导管（110），其包括结合在细长轴（101）内的至少一个内腔; 远端（104），其具有位于内部并被外球囊完全包围的内气囊; 和具有用于通气膨胀流体或医疗器械中的至少一个的适配器的近端（102）; 以及包括尺寸适于穿过所述细长轴（101）的内腔的外径的光纤（106）; 具有给定长度的非线性发光部分（158），其中去除了来自非线性发光部分（158）的包层材料的一部分，使得沿着非线性发光部分（158）的长度发射光能部分（158）; 以及用于将光引向非线性发光部分（158）的线性细长部分（148）。

7. 发明申请

WO2009088927A1 APPARATUS AND METHODS FOR SEPARATING INTERNAL BONE FIXATION DEVICE FROM INTRODUCER 审中-公开
标题翻译：从引言器分离内固定装置的装置和方法
公开(公告)号：WO2009088927A1
公开(公告)日：2009-07-16
申请号：PCT/US2008/088638
申请日：2008-12-31
申请人： ILLUMINOSS MEDICAL, INC. , COLLERAN, Dennis, P. , RABINER, Robert, A. , DYE, Justin, G. , CHANG, Narissa, Y. , MORIN, Joshua, M.
发明人： COLLERAN, Dennis, P. , RABINER, Robert, A. , DYE, Justin, G. , CHANG, Narissa, Y. , MORIN, Joshua, M.
IPC分类号： A61B17/88
CPC分类号： A61B17/7275 , A61B17/7097 , A61B17/8863 , A61B2017/2905
摘要： Apparatus and methods for separating an internal bone fixation device from an introducer are disclosed herein. A device (100) for separating an internal bone fixation device (210) from an introducer (201) includes a functional portion (110) having an outer shaft (115) surrounding and controlling operation of a cutting mechanism (105); and a control portion (101) having an actuating mechanism (160) for initiating activation of the outer shaft (115).
摘要翻译：本文公开了用于将内骨固定装置与导引器分离的装置和方法。一种用于从导入器（201）分离内部骨固定装置（210）的装置（100）包括具有围绕并控制切割机构（105）的操作的外轴（115）的功能部（110）。和具有用于启动外轴（115）的启动的致动机构（160）的控制部分（101）。

8. 发明申请

WO2007127255A3 APPARATUS AND METHODS FOR REINFORCING BONE 审中-公开
公开(公告)号：WO2007127255A3
公开(公告)日：2007-11-08
申请号：PCT/US2007/010038
申请日：2007-04-26
申请人： ILLUMINOSS MEDICAL, INC. , RABINER, Robert, A.
发明人： RABINER, Robert, A.
IPC分类号： A61B17/56
摘要： Apparatuses and methods for reinforcing weakened or fractured bone (40) are disclosed. An apparatus for delivering a bone reinforcing mixture to a bone (40) includes a tube (22) having a proximal end (27), a distal end (23), and a longitudinal axis therebetween, wherein the tube (22) has at least one inner lumen (24) capable of allowing a bone reinforcing mixture to pass through, and a bone fitting portion (30) having an opening for accepting the tube (22), an insertion portion for insertion into the bone (40), and at least one relief valve (36).

9. 发明申请

WO2010050965A1 SYSTEMS AND METHODS FOR INTERNAL BONE FIXATION 审中-公开
标题翻译：用于内固定的系统和方法
公开(公告)号：WO2010050965A1
公开(公告)日：2010-05-06
申请号：PCT/US2008/081924
申请日：2008-10-31
申请人： ILLUMINOSS MEDICAL, INC. , RABINER, Robert, A. , COLLERAN, Dennis, P. , O'LEARY, Anthony, W. , DYE, Justin, G. , DREW, Mark, A.
发明人： RABINER, Robert, A. , COLLERAN, Dennis, P. , O'LEARY, Anthony, W. , DYE, Justin, G. , DREW, Mark, A.
IPC分类号： A61B17/56
CPC分类号： A61B17/8836 , A61B90/39 , A61B2090/306 , A61B2090/3983
摘要： Internal bone fixation devices and methods for using the devices for repairing a weakened or fractured bone are disclosed herein. According to aspects illustrated herein, there is provided a device (700) for repairing a fractured bone that includes a delivery (710) having an elongated shaft (701) with a proximal end, a distal end, and a longitudinal axis therebetween, the delivery catheter (710) having an inner void (713) for passing at least one reinforcing material, and an inner lumen (711) for accepting a light pipe (652), wherein a distal end (723) of the inner lumen (711) terminates in an optical lens (754); a conformable member (703) releasably engaging the distal end of the delivery catheter (710), the conformable member (703) moving from a deflated state to an inflated state when the at least one reinforcing material is delivered to the conformable member (703); and an adapter releasably engaging the proximal end of the delivery catheter (710) for receiving the light pipe (652) and the at least one reinforcing material.
摘要翻译：本文公开了内部骨固定装置和使用该装置来修复弱化骨或骨折骨的方法。根据本文所示的方面，提供了一种用于修复断裂骨的装置（700），其包括具有细长轴（701）的输送（710），其具有近端，远端和其间的纵向轴线，所述输送具有用于通过至少一种增强材料的内部空隙（713）的导管（710）和用于接受光管（652）的内腔（711），其中内腔（711）的远端（723）终止在光学透镜（754）中; 可释放地接合输送导管（710）的远端的适形构件（703），当至少一个增强材料被输送到适形构件（703）时，适形构件（703）从放气状态移动到膨胀状态， ; 以及可释放地接合所述输送导管（710）的近端以用于接收所述光管（652）和所述至少一种增强材料的适配器。

10. 发明申请

WO2009082688A1 APPARATUS AND METHODS FOR REPAIRING CRANIOMAXILLOFACIAL BONES USING CUSTIOMIZED BONE PLATES 审中-公开
标题翻译：使用骨盆修复骨折骨折的装置和方法
公开(公告)号：WO2009082688A1
公开(公告)日：2009-07-02
申请号：PCT/US2008/087630
申请日：2008-12-19
申请人： ILLUMINOSS MEDICAL, INC. , RABINER, Robert, A. , CRISCO, Joseph, John
发明人： RABINER, Robert, A. , CRISCO, Joseph, John
IPC分类号： A61B17/58
CPC分类号： A61B17/8061 , A61B17/8085
摘要： Bone plates and methods of using the bone plates for adjoining bone fragments are disclosed herein. A device (100) for adjoining at least two bone fragments includes a delivery catheter (110) having an elongated shaft (101) with a proximal end (102), a distal end (104), and a longitudinal axis therebetween, wherein the delivery catheter (110) has an inner void (113) for passage of at least one filling material and an inner lumen for passage of a light source (150); a conformable bone plate (103) releasably engaging the distal end of the delivery catheter (104), wherein the conformable bone plate (103) has a first surface (133), a second surface (143), a proximal end (123), and a distal end and at least one aperture extending from the first surface (133) to the second surface (143) for receiving a fastener (163); and an adapter releasably engaging the proximal end of the delivery catheter (102) for receiving the light source (150) and a delivery system housing the at least one filling material.
摘要翻译：本文公开了骨板和使用骨板来邻接骨碎片的方法。用于邻接至少两个骨碎片的装置（100）包括具有细长轴（101）的输送导管（110），其具有近端（102），远端（104）和其间的纵向轴线，其中所述输送导管（110）具有用于使至少一个填充材料通过的内部空间（113）和用于通过光源（150）的内腔。可释放地接合输送导管（104）的远端的适形骨板（103），其中适形骨板（103）具有第一表面（133），第二表面（143），近端（123），以及从所述第一表面（133）延伸到所述第二表面（143）的远端和至少一个孔，用于接收紧固件（163）; 以及可释放地接合所述输送导管（102）的近端以用于接收所述光源（150）的适配器和容纳所述至少一种填充材料的输送系统。

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