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1. 发明申请

WO2017034868A1 IN-LINE PRESSURE ACCUMULATOR AND FLOW-CONTROL SYSTEM FOR BIOLOGICAL OR CHEMICAL ASSAYS 审中-公开
标题翻译：用于生物或化学测试的在线压力累加器和流量控制系统
公开(公告)号：WO2017034868A1
公开(公告)日：2017-03-02
申请号：PCT/US2016/047253
申请日：2016-08-17
申请人： ILLUMINA, INC.
发明人： STONE, Michael, J. , DREWS, Brad , WILLIAMSON, Erik
IPC分类号： G01N35/10
CPC分类号： G01N35/1095
摘要： Flow-control system includes a fluid reservoir configured to store a fluid, a pressure accumulator in flow communication with and positioned downstream from the fluid reservoir, and a loading zone that is configured to receive and fluidly couple to a flow cell having a biological or chemical sample. The loading zone is in flow communication with and positioned downstream from the pressure accumulator. The flow-control system also includes a system pump in flow communication with and positioned downstream from the loading zone. The system pump is configured to induce a flow of the fluid from the fluid reservoir and through the pressure accumulator and the loading zone. The pressure accumulator is configured to receive fluid from the fluid reservoir during a filling operation. The pressure accumulator is configured to impart pressure on the fluid and drive the fluid toward the loading zone during a pressure-assist operation.
摘要翻译：流量控制系统包括被配置为存储流体的流体储存器，与流体储存器流动连通并位于流体储存器下游的压力存储器，以及被配置为接收流体耦合到具有生物或化学物质的流动池的装载区样品。装载区与蓄压器流动连通并位于压力蓄能器的下游。流量控制系统还包括与装载区域流动连通并位于装载区域下游的系统泵。系统泵被配置为引起流体从流体储存器流过并通过压力蓄能器和装载区域的流动。压力蓄能器构造成在填充操作期间从流体储存器接收流体。压力蓄能器构造成在压力辅助操作期间向流体施加压力并将流体驱动到装载区域。

2. 发明申请

WO2017123533A1 DETECTION APPARATUS HAVING A MICROFLUOROMETER, A FLUIDIC SYSTEM, AND A FLOW CELL LATCH CLAMP MODULE 审中-公开
标题翻译：具有微型流量计的检测装置，流体系统和流动池闩锁模块
公开(公告)号：WO2017123533A1
公开(公告)日：2017-07-20
申请号：PCT/US2017/012822
申请日：2017-01-10
申请人： ILLUMINA, INC. , ILLUMINA SINGAPORE PTE LTD
发明人： ANG, Beng, Keong , CHENG, Heng, Kuang , BEIRLE, John, M. , DREWS, Brad , KAPLAN, David
IPC分类号： G01N21/64
CPC分类号： G01N35/00029 , B01L3/502715 , B01L9/527 , G01N21/6428 , G01N21/645 , G01N21/6456 , G01N21/6486 , G01N35/0099 , G01N35/021 , G01N35/04 , G01N35/1002 , G01N35/1095 , G01N2021/6482 , G01N2035/00158 , G01N2035/00237 , G01N2035/00326 , G01N2035/00356 , G01N2035/0465
摘要： Detection apparatus includes a microfluorometer having an objective, an excitation radiation source, and a detector. The detection apparatus also includes a fluidic system for delivering reagents from a reagent cartridge to a flow cell. The fluidic system includes a manifold body having a plurality of fluidic channels configured for fluid communication between the reagent cartridge and the flow cell. The fluidic system also includes a plurality of reagent sippers. The fluidic system also includes a valve configured to mediate fluid between reagent reservoirs and the flow cell. The detection apparatus also includes a flow cell latch clamp module having a clamp cover for holding the flow cell. The objective is configured to direct excitation radiation from the radiation source to the flow cell and to direct emission from the flow cell to the detector. The microfluorometer is movable to acquire wide-field images of different areas of the flow cell.
摘要翻译：检测设备包括具有物镜，激发辐射源和检测器的微荧光计。检测装置还包括用于将试剂从试剂筒输送到流通池的流体系统。该流体系统包括具有多个流体通道的歧管主体，该多个流体通道被配置成用于在试剂盒与流通池之间的流体连通。流体系统还包括多个试剂吸管。流体系统还包括构造成介导试剂储器与流动池之间的流体的阀。检测装置还包括流通池闩锁夹持模块，其具有用于保持流通池的夹持盖。该物镜被配置成将来自辐射源的激发辐射引导至流动池并将来自流动池的发射引导至检测器。该荧光计可移动以获取流动池不同区域的宽视场图像。

3. 发明申请

WO2015116591A1 COMPOSITIONS AND METHODS FOR DISPENSING REAGENTS 审中-公开
标题翻译：用于分配试剂的组合物和方法
公开(公告)号：WO2015116591A1
公开(公告)日：2015-08-06
申请号：PCT/US2015/013091
申请日：2015-01-27
申请人： ILLUMINA, INC.
发明人： HAGE, Matthew , KUHN, Kenneth, M. , DREWS, Brad , WYSHAK, Keih , BLAUWKAMP, Tim
IPC分类号： B01L3/00
CPC分类号： B01L3/527 , B01L3/5025 , B01L2200/025 , B01L2200/0642 , B01L2200/16 , B01L2300/04 , B01L2300/041 , B01L2300/0829 , B01L2300/0838 , B01L2400/0403 , B01L2400/0409 , B01L2400/0433 , B01L2400/0487 , B01L2400/0688 , Y10T436/2575
摘要： Some embodiments of the methods and compositions provided herein include inversion plates and delivery plates. Such inversion plates and delivery plates are useful for the transfer of fluid reagents to multiwell plates.
摘要翻译：本文提供的方法和组合物的一些实施方案包括反转板和递送板。这种反转板和输送板可用于将流体试剂转移至多孔板。

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