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    • 3. 发明申请
    • PROCESS FOR THE PRODUCTION OF ACRYLIC ACID ESTERS CONTAINING CARBOXYL GROUPS
    • 生产含有羧基的丙烯酸酯的方法
    • WO2005030696A1
    • 2005-04-07
    • PCT/EP2004/052264
    • 2004-09-22
    • HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBHROTH, MartinMATSUMOTO, YonetatsuBLÄUER, Hans
    • ROTH, MartinMATSUMOTO, YonetatsuBLÄUER, Hans
    • C07C67/14
    • C09K19/0403C07C67/14C09K2019/0444C07C69/54
    • A process for the production of acrylic esters of general formula (11) by way of reacting a carboxyl group containing hydroxy compound of general formula (a) with acryloyl chloride (c) according to the following general scheme (C): ( II ) wherein A denotes a flexible spacer group, Y a divalent linking group and M a divalent hydrocarbon ring(s) and/or heterocyclic ring(s) containing group containing up to 30 carbon atoms, characterized in that the reaction is carried out a) in the presence of a solvent medium, whereby the solvent medium contains at least 30% per weight based on the total amount of the solvent medium of a solvent selected from the group of N,N-Dimethyl acetamide (DMAc), N­Methyl-pyrrolidon (NMP), N,N,N'N'-Tetramethyl urea (TMU) and N-Methylcaprolactam, b) in the absence of a base, and that c) the reaction temperature is kept between -10'C and +50'C; said process is especially suitable for obtaining products in high yield and purity in an industrial scale.
    • 通过使通式(a)的含羧基的羟基化合物与丙烯酰氯(c)按照以下一般方案(C)反应制备通式(11)的丙烯酸酯的方法:(II)其中 A表示柔性间隔基,Y表示二价连接基,M表示含有至多30个碳原子的二价烃环和/或含杂环,其特征在于反应在 溶剂介质的存在,其中溶剂介质基于选自N,N-二甲基乙酰胺(DMAc),N-乙基 - 吡咯烷酮(NMP)的溶剂的溶剂介质的总量至少为30重量% ,N,N,N'-二甲基脲(TMU)和N-甲基己内酰胺,b)在不存在碱的情况下,和c)将反应温度保持在-10℃和+ 50℃之间; 所述方法特别适用于以工业规模获得高产率和纯度的产品。