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1. 发明申请

WO1990008532A2 PREPARATION FOR DENTAL AND ORAL HYGIENE CONTAINING POLYSACCHARIDE-SPLITTING ENZYMES 审中-公开
标题翻译：含有多糖分解酶的牙科和口腔卫生用品的制备
公开(公告)号：WO1990008532A2
公开(公告)日：1990-08-09
申请号：PCT/EP1990000144
申请日：1990-01-26
申请人： HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN , KLÜPPEL, Hans-Jürgen , FÖRG, Franz
发明人： HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
IPC分类号： A61K07/28
CPC分类号： A61Q11/00 , A61K8/604 , A61K8/66 , Y10S514/901
摘要： A preparation for dental and oral hygiene containing polysaccharide-splitting enzymes, in particular dextronase, includes as surface active agents, which are tolerated by the enzymes, have a good foaming behaviour and good wetting properties, alkylglycosides, preferably of general formula RO-(C6H10O5)x-H, where R is the aliphatic residue of a primary fatty alcohol with 8 to 22 atoms of C and -(C6H10O5)x-H is an oligoglycoside residue with a mean degree of oligomerisation x comprised between 1 and 10, preferably between 1 and 3.
摘要翻译：包含多糖分解酶，特别是葡聚糖酶的牙科和口腔卫生制剂包括作为酶耐受的表面活性剂，具有良好的起泡性能和良好的润湿性能，烷基糖苷类，优选通式为RO-（C 6 H 10 O 5 ）xH，其中R是具有8至22个C原子的伯脂肪醇的脂肪族残基， - （C 6 H 10 O 5）x H是平均低聚度x的寡糖苷残基，其含量在1和10之间，优选在1和3之间。

2. 发明申请

WO1991002510A1 PLAQUE-INHIBITING MOUTH AND DENTAL CARE PREPARATIONS 审中-公开
标题翻译：抑郁症和牙科护理准备
公开(公告)号：WO1991002510A1
公开(公告)日：1991-03-07
申请号：PCT/EP1990001290
申请日：1990-08-07
申请人： HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN , KLÜPPEL, Hans-Jürgen , FABRY, Bernd
发明人： HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
IPC分类号： A61K07/16
CPC分类号： A61K8/556 , A61Q11/00
摘要： Described are mouth and dental care preparations with improved action against the formation of plaque and containing as their active ingredients sulphophosphoric acid salts of the formula (I) in which R and R , independently of each other, are hydrogen, or the cation M and R together form the group -(OCnH2n)x-O-R -SO3 M , R is an alkylene, hydroxyalkylene or alkenylene group with 8-22 C-atoms, n = 2 or 3, x = 0 or a number between 1 and 30 and M is an alkali metal ion, the ammonium ion or a mono-, di- or trialkanolammonium ion with 2-4 C-atoms in the alkanol group. The preparations inhibit in vitro the dissolution and crystal growth of hydroxyapatite.
摘要翻译：描述了具有改善斑块形成的作用的口腔和牙科护理制剂，并且含有作为其活性成分的式（I）的磺酸磷酸盐，其中R 1和R 2彼此独立地为氢，或阳离子M（+）和R 2一起形成基团 - （OC n H 2n）x OR 3， - （ - ）> M（+）>，R 3是亚烷基，羟基亚烷基或具有8-22个碳原子的亚烯基，n = 2或3，x = 0或1至30之间的数，M（+）是碱金属离子，铵离子或单，二或二在烷醇基团中具有2-4个C原子的三烷醇铵离子。制剂在体外抑制羟磷灰石的溶解和晶体生长。

3. 发明申请

WO1991002511A1 ANTI-PLAQUE TOOTHPASTE 审中-公开
标题翻译：抗粘蛋白
公开(公告)号：WO1991002511A1
公开(公告)日：1991-03-07
申请号：PCT/EP1990001345
申请日：1990-08-16
申请人： HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN , WÜLKNITZ, Peter , LEHMANN, Rudolf , KLÜPPEL, Hans-Jürgen
发明人： HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
IPC分类号： A61K07/16
CPC分类号： A61Q11/00 , A61K8/416 , A61K8/43
摘要： Toothpastes containing 10-60 wt. % of polishing agents, 2-20 wt. % of humectants, 0.5-5 wt. % of water-soluble consistency regulators and 0.05-0.5 wt. % of antimicrobial biguanides as well as 1-5 wt. % of other additives from the group of surface-active substances which contain aromatic oils and sweeteners, have a particularly high biguanide availability if the polishing agent consists main of calcium carbonate, the consistency regulators are non-ionic polysaccharide derivatives and the surface-active substances are a cationic tenside with a linear alkyl group containing 12-18 carbon atoms and one or two tertiary amino groups or quaternary ammonium groups and possibly a non-ionogenic solubilizer for the aromatic oil.
摘要翻译：牙膏含10-60wt。抛光剂％，2-20wt。％的保湿剂，0.5-5wt。％的水溶性稠度调节剂和0.05-0.5wt。抗菌双胍的百分比以及1-5wt。含有芳香油和甜味剂的一类表面活性物质的其他添加剂的百分比，如果抛光剂主要由碳酸钙组成，则稳定性调节剂是非离子多糖衍生物和表面活性物质是具有包含12-18个碳原子的直链烷基和一个或两个叔氨基或季铵基团的阳离子表面活性剂，并且可能是用于芳族油的非电离增溶剂。

4. 发明申请

WO1991011986A1 MOUTH WASHES AND DENTIFRICES 审中-公开
标题翻译：洗涤剂和牙膏
公开(公告)号：WO1991011986A1
公开(公告)日：1991-08-22
申请号：PCT/EP1991000164
申请日：1991-01-29
申请人： HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN , MÖLLER, Hinrich , KLÜPPEL, Hans-Jürgen , WÜLKNITZ, Peter
发明人： HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
IPC分类号： A61K07/16
CPC分类号： A61K8/416 , A61K8/55 , A61Q11/00
摘要： Mouth washes and dentifrices containing, as active ingredients, phosphoric acid esters of certain amino alcohols or their salts or quaternization products of alkoxylation products of these compounds have an improved anticariogenic action. Preferred substances include phosphorylated N-[tris(hydroxymethyl)methyl]-ethanolamine, N-tris(hydroxymethyl)methyl]-diethanolamine + 1 EO, [tris(hydroxyethyl)-[tris(hydroxymethyl)methyl]ammonium chloride,m N-[tris(hydroxymethyl)methyl]-diethanolamine + 3 EO and 2-[bis(2-hydroxyethyl)amino]-2-methyl-propane-1,3-diol.

5. 发明申请

WO1991009589A2 MOUTH AND TOOTH CARE PREPARATIONS 审中-公开
标题翻译：口腔和牙齿护理制剂
公开(公告)号：WO1991009589A2
公开(公告)日：1991-07-11
申请号：PCT/EP1990002171
申请日：1990-12-13
申请人： HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN , MÖLLER, Hinrich , KLÜPPEL, Hans-Jürgen , WÜLKNITZ, Peter
发明人： HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
IPC分类号： A61K07/16
CPC分类号： A61K8/556 , A61Q11/00
摘要： The invention concerns mouth and tooth care preparations which provide improved protection against the formation of caries and which contain as their active ingredient a phosphoric acid ester of a cycloalkane carboxylic acid or of a salt of a cycloalkane carboxylic acid of the general formula (I) in which z is a whole number from 4 to 7, the individual R groups are, independently of each other, hydrogen or -(OCnH2n)m-OR2, n being a whole number from 2 to 5, m a number from 0 to 8 and R¿n? hydrogen or a -PO3M2 group, and M being hydrogen, an alkali metal or alkaline-earth metal ion, an ammonium ion or a mono-, di- or trihydroxyalkylammonium group with 2-4 carbon atoms in the hydroxyalkyl group, at least three of the R groups in the molecule being -(OCnH2n)m-OR?2¿ and at least one R2 group in the molecule being -PO¿3?M2, and/or a phosphoric acid ester of cycloalkene carboxylic acid or of a salt of a cycloalkene carboxylic acid derived from the group of compounds represented by formula (I) by the theoretical removal of a hydrogen atom from each of two neighbouring carbon atoms and to form a C=C double bond between these two carbon atoms. Preferred are phosphorylated, optionally ethoxylated, quinic acid and shikimic acid as their alkali metal salts.
摘要翻译：的口腔卫生产品共享提高的抗龋形成包含作为活性物质的羧酸环烷烃的磷酸酯或通式环烷烃（I）的羧酸的盐，其中 z表示4-7的整数，各R基团独立地表示彼此，氢或 - （OCñħ2N）M-OR2，其中n是从2至5的整数，n为0的数至8和R 2是氢或-PO 3 M 2基团，M为氢，碱金属离子或碱土金属，铵基或单 - ，二 - 或trihydroxyalkylammonium具有2至4个碳原子的（OCñħ2N）米或2，并且至少一个R 2基团= -PO3M2存在的分子和/或羧酸或环烯的磷酸酯在 - 羟烷基，其中R代表基团的至少三个在环烯烃羧酸盐，正式生产从根据式（I）的化合物中消除了两个相邻碳原子上的氢原子并且在这两个碳原子之间形成了C = C双键。优选采用磷酸化的奎尼酸和莽草酸，并且如果合适的话，以其碱性盐形式乙氧基化。

6. 发明申请

WO1990006744A2 TOOTHPASTE 审中-公开
标题翻译：牙膏
公开(公告)号：WO1990006744A2
公开(公告)日：1990-06-28
申请号：PCT/EP1989001476
申请日：1989-12-04
申请人： HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN , KORNETTKA, Norbert , FÖRG, Franz , STÖFFLER, Albert , FIEDLER, Jürgen
发明人： HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
IPC分类号： A61K07/16
CPC分类号： B65D35/242 , A61K8/02 , A61K8/0237 , A61Q11/00
摘要： Multicolour-striped strips of toothpaste, in particular with a cross-section in the form of an n-sided polygon, where n is a whole number between 3 and 7, can be extruded from a reservoir, without diffuse transition regions, if the ratio of the liquid limits of the carrier material and of the stripe material is approximately 1.10 : 1 to 1.20 : 1. A suitable extruder is shown in Figure 1.

7. 发明申请

WO1994010969A1 REMINERALIZING TOOTH-CARE AGENT 审中-公开
标题翻译：再矿化牙齿保健
公开(公告)号：WO1994010969A1
公开(公告)日：1994-05-26
申请号：PCT/EP1993002991
申请日：1993-10-28
申请人： HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN , SCHUHMANN, Klaus , FÖRG, Franz , LASKA, Hans
发明人： HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
IPC分类号： A61K07/16
CPC分类号： A61K8/21 , A61K8/24 , A61K8/25 , A61Q11/00
摘要： Proposed is a toothpaste with the usual components and containing as the polishing agent a combination of silicilic acids and dicalcium phosphate dihydrate (brushite), this toothpaste having a particularly effective restoring action on the tooth surface. This action is due to controlled remineralization in, in particular, enamel scratches and Tomes' pits. This action can be reinforced by the addition of magnesium ions and/or fluorophosphate ions.

8. 发明申请

WO1991002513A1 ANTI-PLAQUE TOOTHPASTE 审中-公开
标题翻译：抗粘蛋白
公开(公告)号：WO1991002513A1
公开(公告)日：1991-03-07
申请号：PCT/EP1990001346
申请日：1990-08-16
申请人： HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN , WÜLKNITZ, Peter , LEHMANN, Rudolf , PLÖGER, Walter , FÖRG, Franz
发明人： HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
IPC分类号： A61K07/22
CPC分类号： A61Q11/00 , A61K8/26 , A61K8/43 , A61K8/604
摘要： Toothpastes containing 10 - 60 wt. % of polishing agents, 2 - 20 wt. % of humectants, 0.5 - 5 wt. % of water-soluble consistency regulators and 0.05 - 0.5 wt. % of antibacterial biguanides as well as 1 - 5 wt. % of other additives from the group of surface active-substances which contain aromatic oils and sweeteners, have a particularly high biguanide availability if the polishing agent is essentially alpha -aluminium oxide-trihydrate, the consistency regulators are non-ionic polysaccharide derivatives, the surface-active substances are an alkyl glycoside and possibly a non-ionogenic solubilizer for the aromatic oil and the sweetener is methyl L-aspartyl-L-phenylalanate.
摘要翻译：牙膏含有10〜60wt。抛光剂％，2-20wt。％的湿润剂，0.5-5wt。％的水溶性稠度调节剂和0.05-0.5wt。抗菌双胍的百分比以及1-5重量％含有芳香油和甜味剂的表面活性物质组中的其他添加剂的百分比如果抛光剂基本上是三氧化二铝 - 三水合物，则具有特别高的双胍可用性，稠度调节剂是非离子多糖衍生物，表面活性物质是烷基糖苷，并且可能是芳族油的非离子型增溶剂，甜味剂是L-天冬氨酰基-L-苯丙氨酸甲酯。

9. 发明申请

WO1994001080A3 LIQUID TOOTH-CLEANING AGENTS 审中-公开
公开(公告)号：WO1994001080A3
公开(公告)日：1994-01-20
申请号：PCT/EP1993001701
申请日：1993-07-01
申请人： HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN , SCHUMANN, Klaus , FÖRG, Franz , GUTZSCHEBAUCH, Claus
发明人： HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
IPC分类号： A61K07/16

10. 发明申请

WO1991002046A1 POWDERED PREPARATIONS OF SURFACE ACTIVE ALKYLGLYCOSIDES 审中-公开
标题翻译：表面活性烷基胆甾醇的制备
公开(公告)号：WO1991002046A1
公开(公告)日：1991-02-21
申请号：PCT/EP1990001226
申请日：1990-07-26
申请人： HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN , HILL, Karlheinz , FÖRG, Franz , KÖRNER, Hermann , PENNINGER, Josef
发明人： HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN
IPC分类号： C11D01/66
CPC分类号： A61Q11/00 , A61K8/604 , C11D1/662 , Y10T428/2991 , Y10T428/2993
摘要： Powdered preparations of surface active alkylglycosides containing 5 - 65 wt.% of a surface active alkylglycoside and 35 - 95 wt.% of an inert inorganic carrier are obtained by mixing the raw product produced in the industrial manufacture of the alkylglycosides with water and an inorganic particulate carrier, e.g. silicic acid, chalk or sodium chloride, and drying the mixture. Preferred powdered preparations contain 20 - 50 wt.% of the alkylglycoside and 50 - 80 wt.% of an inert inorganic carrier.

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