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    • 3. 发明申请
    • METHOD OF CONFERRING RESISTANCE AGAINST A FUSARIUM PLANT DISEASE
    • 对抗植物病害抗性的方法
    • WO2016193214A1
    • 2016-12-08
    • PCT/EP2016/062167
    • 2016-05-30
    • UNIVERSITÄT HAMBURG
    • BORMANN, JörgHEINZE, CorneliaSCHÄFER, Wilhelm
    • C12N15/82A01H5/10
    • C12N15/8282A01H5/10C07K14/415C12N15/8218C12N2310/14C12N2310/141
    • The invention relates to a method of conferring to a plant resistance against a plant disease caused by a Fusarium species, to a transgenic Fusarium -resistant plant, to a double-stranded RNA and a composition comprising same. Object of the invention is the provision of means for reducing susceptibility of food crops, in particular cereals, to fungal attack. For this purpose, the present invention provides in one aspect a method of conferring to a plant resistance against a plant disease caused by a Fusarium species, the method comprising genetically engineering the plant in a manner to enable host-induced gene silencing of a Fusarium gene encoding CSX1 having or comprising the amino acid sequence of SEQ ID NO: 2 or of a Fusarium gene encoding a protein sharing at least 55%, 60%, 65%, 70%, 75%, 80%, 85%, 90%, 95%, 96%, 97%, 98%o or 99% sequence identity with the amino acid sequence of SEQ ID NO: 2.
    • 本发明涉及赋予植物对由镰孢属物种引起的植物病害抗转基因镰刀菌抗性植物对双链RNA及其组合物的抗性的方法。 本发明的目的是提供减少粮食作物,特别是谷物对真菌侵袭的敏感性的手段。 为此,本发明在一个方面提供赋予植物对由镰孢属物种引起的植物病害抗性的方法,所述方法包括以能使宿主诱导的镰刀菌基因的基因沉默的方式遗传工程化植物 编码具有或包含SEQ ID NO:2的氨基酸序列的CSX1或编码分享至少55%,60%,65%,70%,75%,80%,85%,90%的蛋白质的Fusarium基因, 与SEQ ID NO:2的氨基酸序列具有95%,96%,97%,98%或99%的序列同一性。