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1. 发明申请

WO2008036156A1 CEREBRAL VASCULATURE DEVICE 审中-公开
标题翻译：胚胎血管装置
公开(公告)号：WO2008036156A1
公开(公告)日：2008-03-27
申请号：PCT/US2007/017259
申请日：2007-08-01
申请人： GORE ENTERPRISE HOLDINGS, INC. , TRAPP, Benjamin, M. , FRIEDMAN, Nathan, L. , VONESH, Michael, J.
发明人： TRAPP, Benjamin, M. , FRIEDMAN, Nathan, L. , VONESH, Michael, J.
IPC分类号： A61B17/22 , A61B17/12 , A61F2/01 , A61M29/02
CPC分类号： A61B17/320725 , A61B17/12022 , A61B17/12045 , A61B17/12109 , A61B17/12113 , A61B17/1214 , A61B17/12172 , A61B17/221 , A61B2017/12127 , A61B2017/320716 , A61F2/013 , A61F2002/016 , A61F2002/018 , A61F2230/0065 , A61F2230/0069 , A61F2230/0071 , A61F2230/0078
摘要： Novel cerebral vasculature devices are disclosed, including thrombectomy removal devices that include a continuous braided structure, a proximal portion, a distal portion, and a first expandable portion located between the proximal portion and the distal portion. The braided structure includes a plurality of wires. The proximal portion and the distal portion include polymer imbedded at least partially into the braided structure. The device is useful for removing thrombus from a patient's vasculature.
摘要翻译：公开了新颖的脑血管装置，包括包括连续编织结构，近端部分，远端部分和位于近端部分和远端部分之间的第一可扩张部分的血栓切除术去除装置。编织结构包括多根线。近端部分和远端部分包括至少部分地嵌入编织结构中的聚合物。该装置可用于从患者的脉管系统中去除血栓。

2. 发明申请

WO2007109007A1 ENDOPROSTHESIS HAVING MULTIPLE HELICALLY WOUND FLEXIBLE FRAMEWORK ELEMENTS 审中-公开
标题翻译：具有多个简单易行的框架元件的内窥镜
公开(公告)号：WO2007109007A1
公开(公告)日：2007-09-27
申请号：PCT/US2007/006252
申请日：2007-03-12
申请人： GORE ENTERPRISE HOLDINGS, INC. , CULLY, Edward, H. , HUPPENTHAL, Joseph, A. , VONESH, Michael, J.
发明人： CULLY, Edward, H. , HUPPENTHAL, Joseph, A. , VONESH, Michael, J.
IPC分类号： A61F2/88
CPC分类号： A61F2/88 , A61F2/07 , A61F2/90 , A61F2002/075 , A61F2250/0014
摘要： The present invention is directed to an implantable medical device having two or more flexible framework elements helically disposed around a common central axis. Each framework element has a configuration having a series of apices alternating in direction. The framework elements are arranged together in the helical winding so the apices are in a nested relationship. Adjacent apices are connected to one another with flexible linkage elements. Each linkage element follows a distinct pathway or course through the framework elements. The elements can each be made of the same or different materials.
摘要翻译：本发明涉及一种可植入医疗装置，其具有围绕公共中心轴线螺旋设置的两个或更多个柔性框架元件。每个框架元件具有在方向上交替的一系列顶点的构造。框架元件一起布置在螺旋绕组中，使得顶点处于嵌套关系。相邻的顶点通过柔性联动元件相互连接。每个连接元件遵循通过框架元件的不同的途径或过程。元件可以由相同或不同的材料制成。

3. 发明申请

WO2004066809A2 DEPLOYMENT SYSTEM FOR AN ENDOLUMINAL DEVICE 审中-公开
标题翻译：内分泌装置的部署系统
公开(公告)号：WO2004066809A2
公开(公告)日：2004-08-12
申请号：PCT/US2004/001046
申请日：2004-01-14
申请人： GORE ENTERPRISE HOLDINGS, INC. , BRUUN, Steven, R. , CULLY, Edward, H. , MANN, James, W. , ULM, Mark, J. , VONESH, Michael, J.
发明人： BRUUN, Steven, R. , CULLY, Edward, H. , MANN, James, W. , ULM, Mark, J. , VONESH, Michael, J.
IPC分类号： A61B
CPC分类号： A61F2/966 , A61F2/95 , A61F2/958 , A61F2/97 , A61F2002/9511
摘要： The present invention is directed to a deployment system for an endoluminal device. The deployment system includes a confining sheath placed around a compacted endoluminal device. A deployment line is provided in the system that is an integral extension of the sheath. As the deployment line is actuated, the sheath retracts from around the compacted endolurninal device. As the sheath retracts from around the endoluminal device, material from the sheath may be converted into deployment line. Once the sheath is retracted from around the compacted endoluminal device, the endoluminal device expands in configuration and repairs vascular or cardiac structures of an implant recipient. Any remaining sheath material is removed from the implantation site along with the deployment line. The deployment system also includes an endo-prosthesis mounting member placed between the endoluminal device and an underlying catheter. The endo-prosthesis mounting member serves to cushion and retain the endoluminal device when constrained by the sheath and may assist in expansion of the endoluminal device when unconstrained by the sheath.
摘要翻译：本发明涉及一种用于腔内装置的部署系统。部署系统包括围绕压实的腔内装置放置的限制鞘。在系统中提供了一个部署线，该线是护套的整体延伸。当部署线被致动时，护套从压实的内部装置周围缩回。当护套从内腔装置周围缩回时，来自护套的材料可以被转换成展开线。一旦护套从紧凑的腔内装置周围缩回，腔内装置在构型上扩张并修复植入物接受者的血管或心脏结构。任何剩余的护套材料与植入线一起从植入部位移除。所述展开系统还包括放置在腔内装置和下面的导管之间的内腔假体安装构件。假体内固定构件用于在被护套约束时缓冲和保持内腔装置，并且可以在不受护套约束时有助于腔内装置的膨胀。

4. 发明申请

WO2007127082A1 EXPANDABLE STENT WITH WRINKLE-FREE ELASTOMERIC COVER 审中-公开
标题翻译：具有无皱弹性体覆盖层的膨胀柄
公开(公告)号：WO2007127082A1
公开(公告)日：2007-11-08
申请号：PCT/US2007/009250
申请日：2007-04-13
申请人： GORE ENTERPRISE HOLDINGS, INC. , CULLY, Edward, H. , VONESH, Michael, J.
发明人： CULLY, Edward, H. , VONESH, Michael, J.
IPC分类号： A61F2/06 , A61F2/90
CPC分类号： A61F2/07 , A61F2/91 , A61F2/915 , A61F2002/072 , A61F2002/075 , A61F2002/91508 , A61F2002/91525 , A61F2002/91541 , A61F2220/005
摘要： An improved stent-graft device is provided that delivers a smooth flow surface over a range of operative expanded diameters by applying a unique cover material to the stent through a technique that allows the cover to become wrinkle-free prior to reaching fully deployed diameter. The unique cover material then allows the device to continue to expand to a fully deployed diameter while maintaining a smooth and coherent flow surface throughout this additional expansion. Employed with a self-expanding device, when the device is unconstrained from a compacted diameter it will self-expand up to a fully deployed diameter with the graft being substantially wrinkle-free over diameters ranging from about 30-50% to 100% of the fully deployed diameter. Preferably, the graft component comprises an elastomeric material, such as silicone, polyurethane, or a copolymer of PAVE-TFE.
摘要翻译：提供了一种改进的支架移植装置，其通过使覆盖物在达到完全展开的直径之前变得无皱纹的技术，通过将独特的覆盖材料施加到支架上，在一定范围的工作扩张直径上提供平滑的流动表面。独特的覆盖材料然后允许设备继续扩展到完全展开的直径，同时在整个这种额外的扩展中保持平滑和一致的流动表面。采用自扩张装置，当装置不受压实直径的限制时，其将自膨胀直至完全展开的直径，其中移植物基本上无皱纹，直径范围为约30-50％至100％完全展开直径。优选地，接枝组分包括弹性体材料，例如聚硅氧烷，聚氨酯或PAVE-TFE的共聚物。

5. 发明申请

WO2007084762A2 DEVICE FOR RAPID REPAIR OF BODY CONDUITS 审中-公开
标题翻译：身体快速修复装置
公开(公告)号：WO2007084762A2
公开(公告)日：2007-07-26
申请号：PCT/US2007/001645
申请日：2007-01-19
申请人： GORE ENTERPRISE HOLDINGS, INC. , CULLY, Edward, H. , DUNCAN, Jeffrey, B. , FLURY, Keith, M. , GOODMAN, Paul, D. , HOUSE, Wayne, D. , LEVERING, Vrad, W. , OFF, Philip, P. , O'SHEA, Daniel, M. , VONESH, Michael, J. , WIERSDORF, Jason, M.
发明人： CULLY, Edward, H. , DUNCAN, Jeffrey, B. , FLURY, Keith, M. , GOODMAN, Paul, D. , HOUSE, Wayne, D. , LEVERING, Vrad, W. , OFF, Philip, P. , O'SHEA, Daniel, M. , VONESH, Michael, J. , WIERSDORF, Jason, M.
IPC分类号： A61F2/94
CPC分类号： A61F2/07 , A61B17/06166 , A61B17/11 , A61B2017/1107 , A61F2/064 , A61F2/844 , A61F2/848 , A61F2/88 , A61F2/89 , A61F2/958 , A61F2/97 , A61F2002/075 , A61F2002/30713 , A61F2220/0075 , A61F2220/0091 , A61F2250/0087
摘要： A self-expanding stent-graft provided in a diametrically compacted state for implantation and retained preferably by a constraining sheath, useful for the temporary or permanent repair of injured, partially or entirely transected body conduits including blood vessels. It may be used under direct visualization to quickly stop or substantially reduce loss of blood from such damaged vessels and to quickly re-establish perfusion distal to the injury site. The device would typically be implanted under emergency room conditions but also be used in field situations by trained medical technicians. After an end of the device is inserted into a blood vessel through the injury access, deployment preferably initiates from the device' end in a direction moving toward the middle of the length of the device by directionally releasing the constraining sheath. In a preferred embodiment, the two opposing ends of the device are individually deployable from the compacted, small diameter intended for insertion into a vessel, to the larger diameter at which they fit interferably into a portion of the vessel.
摘要翻译：自扩张的支架移植物以径向压实状态提供用于植入，并且优选地由约束护套保持，其用于临时或永久性修复包括血管的受损部分或全部横断的身体导管。它可以在直接可视化下使用，以快速停止或显着减少来自这些受损血管的血液损失，并迅速重建在损伤部位远端的灌注。该设备通常将在急诊室条件下植入，但也由经过培训的医疗技术人员在现场使用。在通过伤害通道将装置的一端插入血管之后，展开优选地通过定向释放约束护套从装置的朝向装置长度的中间方向移动的方向开始。在优选实施例中，装置的两个相对的端部可单独地从用于插入容器的压实的小直径展开到其可干燥地配合到容器的一部分中的较大的直径。

6. 发明申请

WO2004064891A2 A PUNCTURABLE CATHETER 审中-公开
标题翻译：可调式导管
公开(公告)号：WO2004064891A2
公开(公告)日：2004-08-05
申请号：PCT/US2004/001241
申请日：2004-01-15
申请人： GORE ENTERPRISE HOLDINGS, INC. , ARMSTRONG, Joseph, R. , CULLY, Edward, H. , FLURY, Keith, M. , VONESH, Michael, J.
发明人： ARMSTRONG, Joseph, R. , CULLY, Edward, H. , FLURY, Keith, M. , VONESH, Michael, J.
IPC分类号： A61M
CPC分类号： A61M25/0043 , A61F2/958 , A61M25/005 , A61M25/0052 , A61M25/10 , A61M2025/0183 , A61M2025/0188 , A61M2025/1056 , A61M2025/1081
摘要： A catheter provided with a guidewire catheter lumen having a thin covering that is easily punctured by a guidewire at virtually any desired point along the catheter length. The thin covering may be integral with the catheter shaft, or may be a separate component that covers only the portion of the catheter shaft immediately adjacent the outer portion of the guidewire lumen, or may be a thin tubular construct that surrounds the entire catheter shaft. The covering is preferably relatively translucent, allowing for good visualization of the location of the end of the guidewire to enable puncturing of the covering at the desired location along the length of the catheter shaft. The covering is also preferably tear resistant at puncture sites. The catheter shaft is preferably made of a material having a color that provides good visibility against an operating field, and more preferably is phosphorescent either entirely or in part. Materials suitable for the catheter shaft are polymeric materials well known in the art; the catheter shaft may optionally be provided with metallic stiffening components such as wires or hypotubes along all or part of the catheter length.
摘要翻译：导管，其具有导线导管管腔，该导管管腔具有薄的覆盖层，其在导管长度的几乎任何所需点处被导丝容易地刺穿。薄的覆盖物可以与导管轴成一体，或者可以是仅覆盖导管轴的紧邻导丝管腔的外部的部分的单独的部件，或者可以是围绕整个导管轴的薄的管状结构。覆盖物优选地是相对半透明的，允许良好地可视化导丝端部的位置，以使得能够沿着导管轴的长度在期望的位置刺穿覆盖物。覆盖物也优选在穿刺部位具有抗撕裂性。导管轴优选由具有对操作场提供良好可见性的颜色的材料制成，更优选地，全部或部分地是磷光。适用于导管轴的材料是本领域公知的聚合材料; 导管轴可以可选地沿着导管长度的全部或部分设置有金属加强部件，例如电线或海波管。

7. 发明申请

WO2010053585A1 IMPLANTABLE LEAD 审中-公开
标题翻译：可塑性铅
公开(公告)号：WO2010053585A1
公开(公告)日：2010-05-14
申请号：PCT/US2009/006051
申请日：2009-11-09
申请人： GORE ENTERPRISE HOLDINGS, INC. , DUNCAN, Jeffrey, B. , HOPKINSON, Aaron, J. , MCDANIEL, Thomas, R. , VONESH, Michael, J. , WIERSDORF, Jason, M.
发明人： DUNCAN, Jeffrey, B. , HOPKINSON, Aaron, J. , MCDANIEL, Thomas, R. , VONESH, Michael, J. , WIERSDORF, Jason, M.
IPC分类号： A61N1/05
CPC分类号： A61N1/05 , A61N1/0563 , Y10T29/49204
摘要： A highly flexible implantable lead that offers improved flexibility, fatigue life and fatigue and abrasion resistance improved reliability, effective electrode tissue contact with a small diameter and low risk of tissue damage during extraction. In one embodiment the lead is provided with both defibrillation electrodes and pacing/sensing electrodes. For defibrillation/pacing leads, the lead diameter may be as small as six French or smaller. The construction utilizes helically wound conductors. For leads incorporating multiple separate conductors, many of the helically wound conductors are arranged in a multi-filar relationship. Preferably, each conductor is a length of wire that is uninsulated at about the middle of its length to create an electrode, wherein the conductor is folded in half at about the middle of the length to create first and second length segments that constitute parallel conductors.
摘要翻译：高度灵活的可植入引线，提供更好的灵活性，疲劳寿命和疲劳和耐磨性，提高了可靠性，有效的电极组织接触具有小直径和低抽提时的组织损伤风险。在一个实施例中，引线设置有除颤电极和起搏/感测电极。对于除颤/起搏引线，引线直径可以小至六法国或更小。该结构采用螺旋缠绕导体。对于并入多个独立导体的引线，许多螺旋缠绕的导体以多丝状关系布置。优选地，每个导体是在其长度的大约中间部分未绝缘的导线的长度以产生电极，其中导体在大约中间的长度处折叠成一半，以形成构成平行导体的第一和第二长度段。

8. 发明申请

WO2009158012A2 IMPROVED CATHETER 审中-公开
标题翻译：改进的导管
公开(公告)号：WO2009158012A2
公开(公告)日：2009-12-30
申请号：PCT/US2009/003804
申请日：2009-06-26
申请人： GORE ENTERPRISE HOLDINGS, INC. , DIETZ, Dennis, R. , MESSICK, David, J. , NORDHAUSEN, Craig, T. , OAKLEY, Clyde, G. , PATTERSON, Ryan, C. , POLENSKE, Jim, H. , WILSON, David, W. , BIELEWICZ, Paul, A. , FIFE, Michael, J. , DENNY, Richard, W. , HUPPENTHAL, Joseph, A. , CULLY, Edward, H. , LATULIPPE, Paul, N. , BLEA, Mark, E. , TITTELBAUGH, Eric, M. , VONESH, Michael, J. , STOLLBERG, Marcus , HENKE, Christian , BUFF, Joachim
发明人： DIETZ, Dennis, R. , MESSICK, David, J. , NORDHAUSEN, Craig, T. , OAKLEY, Clyde, G. , PATTERSON, Ryan, C. , POLENSKE, Jim, H. , WILSON, David, W. , BIELEWICZ, Paul, A. , FIFE, Michael, J. , DENNY, Richard, W. , HUPPENTHAL, Joseph, A. , CULLY, Edward, H. , LATULIPPE, Paul, N. , BLEA, Mark, E. , TITTELBAUGH, Eric, M. , VONESH, Michael, J. , STOLLBERG, Marcus , HENKE, Christian , BUFF, Joachim
IPC分类号： A61B8/12 , A61M25/01 , A61B19/00
CPC分类号： A61B8/12 , A61B8/445 , A61B8/4466 , A61B17/3478 , A61B90/37 , A61B2017/003 , A61B2017/22014 , A61B2017/22039 , A61B2017/2906 , A61B2090/378 , A61B2090/3784 , A61M25/0133 , A61M25/0147 , A61M25/0155 , A61M25/0158 , A61M2025/0004
摘要： An improved catheter is provided. The catheter may include a deflectable member located at a distal end of the catheter. The deflectable member may comprise an ultrasound transducer array. The catheter may include a lumen extending from a proximal end of the catheter to the distal end. The lumen may be used to deliver an interventional device to a point distal to the distal end of the catheter. The deflectable member may be selectively deflectable in a pivot-like manner through an arc of at least 90 degrees. In embodiments where the deflectable member includes an ultrasound transducer array, the ultrasound transducer array may be operable to image both when aligned with the catheter and when pivoted relative to the catheter. When pivoted relative to the catheter, the ultrasound transducer array may have a field of view distal to the distal end of the catheter.
摘要翻译：提供改进的导管。导管可以包括位于导管的远端的可偏转构件。可偏转构件可以包括超声换能器阵列。导管可以包括从导管的近端延伸到远端的内腔。内腔可用于将介入装置输送到远离导管远端的位置。可偏转构件可以以枢轴状方式选择性地偏转至少90度的弧度。在可偏转构件包括超声换能器阵列的实施例中，超声换能器阵列可操作以在与导管对准时以及当相对于导管枢转时成像。当相对于导管枢转时，超声换能器阵列可以具有远离导管远端的视场。

9. 发明申请

WO2009045276A1 RETRIEVAL CATHETER 审中-公开
标题翻译：检索针
公开(公告)号：WO2009045276A1
公开(公告)日：2009-04-09
申请号：PCT/US2008/010821
申请日：2008-09-16
申请人： GORE ENTERPRISE HOLDINGS, INC. , PARODI, Juan, C. , CHEER, John , CULLY, Edward, H. , VONESH, Michael, J. , YOUNG, Jeremy, P.
发明人： PARODI, Juan, C. , CHEER, John , CULLY, Edward, H. , VONESH, Michael, J. , YOUNG, Jeremy, P.
IPC分类号： A61F2/01
CPC分类号： A61F2/013 , A61B2017/22039 , A61F2/958 , A61F2002/011 , A61F2002/9528 , A61F2002/9534 , A61F2230/0006 , A61M2025/018 , A61M2025/0183
摘要： A retrieval catheter operable by a single clinician that will neither displace a deployed stent nor cause undue trauma to the vascular lumen or lesion. The retrieval catheter may be sized to accommodate both a guidewire (26) and a balloon wire. The retrieval catheter is easy to navigate through tortuous passageways and will cross a previously deployed stent or stent-graft easily with minimal risk of snagging on the deployed stent or stent graft. The sheath (22) and dilator (24) are adapted to allow a guidewire or balloon wire to pass through the walls of both and to allow the sheath and dilator to move axially with respect to each other.
摘要翻译：可由单个临床医生操作的取出导管既不会移位部署的支架，也不会对血管腔或病变造成不适当的创伤。取回导管的尺寸可以适应导丝（26）和气球线。检索导管容易通过曲折的通道导航，并且将容易地穿过先前部署的支架或支架移植物，同时在展开的支架或支架移植物上具有最小的阻塞风险。护套（22）和扩张器（24）适于允许导线或气球线穿过两者的壁并允许护套和扩张器相对于彼此轴向移动。

10. 发明申请

WO2007084431A3 REMOVABLE BLOOD CONDUIT FILTER 审中-公开
公开(公告)号：WO2007084431A3
公开(公告)日：2007-07-26
申请号：PCT/US2007/000982
申请日：2007-01-12
申请人： GORE ENTERPRISE HOLDINGS, INC. , CULLY, Edward, H. , HARTMAN, Cody, L. , NORDHAUSEN, Craig, T. , TITTELBAUGH, Eric, M. , VONESH, Michael, J.
发明人： CULLY, Edward, H. , HARTMAN, Cody, L. , NORDHAUSEN, Craig, T. , TITTELBAUGH, Eric, M. , VONESH, Michael, J.
IPC分类号： A61M29/00
摘要： The present invention relates to a non-evertable blood filter that divides the transverse cross sectional area of a venous vessel into three annular regions or zones. The inner zone, the region immediately surrounding the longitudinal axis of the vessel, is maintained in a relatively open state with only minimal interference from the members making up the filter device so that blood flow can be maintained at a relatively normal rate. Concentrically surrounding the inner zone is the intermediate zone, to which captured emboli are directed out of the bloodstream passing primarily through the inner zone. Finally, concentrically surrounding the intermediate zone is the outer zone adjacent to the vessel wall. This is also intended to be kept free of emboli, so that emboli in the bloodstream immediately adjacent the vessel wall are directed away from the wall by the filter design and into the intermediate zone, thereby avoiding the accumulation of emboli adjacent the vessel wall that might otherwise result in stenosis. The blood filter is intended primarily for use as an inferior vena cava filter, although it can be made in a range of sizes allowing its use in blood vessels and particularly venous vessels of differing diameters. The filter is preferably removable.

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