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2. 发明申请

WO2006097745A1 INHALATION DEVICES 审中-公开
标题翻译：吸入装置
公开(公告)号：WO2006097745A1
公开(公告)日：2006-09-21
申请号：PCT/GB2006/000963
申请日：2006-03-16
申请人： GLAXO GROUP LIMITED , LINTERN, Richard, David , PEARSON, Allen, John , RAND, Paul, Kenneth
发明人： LINTERN, Richard, David , PEARSON, Allen, John , RAND, Paul, Kenneth
IPC分类号： A61M15/00 , B65D83/14 , B05B11/00
CPC分类号： A61M15/009 , A61M15/0068 , B05B11/0037 , B05B11/3056 , B65D83/201
摘要： An inhaler for delivering medicament by inhalation comprises a canister (105) and an actuator comprising a housing (111) receiving the canister, and an actuation mechanism (109) for actuating the canister (105). The actuation mechanism (109) comprises a loading member (161) which is fitted to or comprised in the canister (105) and includes a loading section (175) which is in use, acted upon to drive the loading member (161) in an actuating direction from a rest position to a actuated position in which the canister (105) is actuated to deliver medicament. The actuation mechanism also comprises at least one actuating member (163a, b) which is actuatable by a user to drive the loading member (161) in the actuating direction to the actuated position. The at least one actuating member (163a, b) is pivotally coupled to the housing (111) and comprises a gripping element (177) configured to be gripped and depressed by the user in actuating the canister (105).
摘要翻译：用于通过吸入输送药物的吸入器包括罐（105）和致动器，其包括容纳罐的壳体（111）和用于致动罐（105）的致动机构（109）。所述致动机构（109）包括装配在所述罐（105）中或包含在所述罐（105）中的装载构件（161），并且包括在使用中的加载部分（175），所述装载部件用于将所述装载构件致动方向从静止位置驱动到致动位置，在该位置中，罐（105）被致动以输送药物。所述致动机构还包括至少一个致动构件（163a，b），所述致动构件可由使用者致动，以将所述加载构件（161）沿所述致动方向驱动到所述致动位置。所述至少一个致动构件（163a，b）枢转地联接到所述壳体（111）并且包括被夹持元件（177），所述夹紧元件被构造成由使用者在致动所述罐（105）时被夹持和压下。

3. 发明申请

WO2007138084A2 FLUID DISPENSER 审中-公开
标题翻译：流体分配器
公开(公告)号：WO2007138084A2
公开(公告)日：2007-12-06
申请号：PCT/EP2007/055273
申请日：2007-05-30
申请人： GLAXO GROUP LIMITED , LINTERN, Richard, David , PEARSON, Allen, John , RAND, Paul, Kenneth
发明人： LINTERN, Richard, David , PEARSON, Allen, John , RAND, Paul, Kenneth
IPC分类号： B05B11/00
CPC分类号： A61M15/08 , A61M11/00 , A61M11/007 , A61M2206/16 , B05B1/3436 , B05B11/0064 , B05B11/0067 , B05B11/007 , B05B11/3001 , B05B11/3004 , B05B11/3018 , B05B11/307 , B05B11/3074
摘要： A fluid dispenser 10 comprises a dosing chamber 20, a piston member 14, a fluid outlet 52 through which fluid will be dispensed, a fluid conduit 34, 46 for conveying fluid from the dosing chamber towards the fluid outlet, and a seal 50, 54 for sealing the fluid outlet; wherein: the piston member has a first end 22 that acts as a piston within the dosing chamber for: a) pumping fluid from the dosing chamber through the fluid conduit towards the fluid outlet when moved in a first manner relative to the dosing chamber, and b) filling the dosing chamber with fluid from a supply of fluid when moved in a second manner relative to the dosing chamber; the piston member has a second end 42 positioned outside the dosing chamber and forming at least a part of the seal; the seal is movable from a normal closed state, in which the seal prevents fluid communication between the fluid conduit and the fluid outlet, to an open state, in which the seal provides for fluid communication between the fluid conduit and the fluid outlet; and the dispenser is adapted such that movement of the first end of the piston member in the first manner causes fluid in the fluid conduit to be pressurised to an extent sufficient to move the seal from its normal closed state to its open state thereby enabling fluid to be pumped through the fluid outlet. A one-way valve 31 may be carried by the first end of the piston member for controlling the flow of fluid into and out of the dosing chamber. The fluid conduit may comprise a section 34 which extends through the piston member, e.g. a lumen thereof.
摘要翻译：流体分配器10包括计量室20，活塞构件14，流体出口52，流体将被分配到该流体出口52，用于将流体从计量室输送到流体出口的流体导管34,46和密封件50,54 用于密封流体出口; 其中：所述活塞构件具有作为所述计量室内的活塞的第一端22，用于：a）当相对于所述计量室以第一方式移动时，将来自所述计量室的流体通过所述流体导管朝向所述流体出口泵送;以及 b）当以相对于所述计量室的第二方式移动时，从所述流体供应源填充所述计量室; 活塞构件具有定位在计量室外部并形成密封件的至少一部分的第二端42; 密封件可以从正常关闭状态移动，其中密封件防止流体导管和流体出口之间的流体连通到达打开状态，其中密封件提供流体导管和流体出口之间的流体连通; 并且分配器适于使得活塞构件的第一端以第一方式的运动使得流体导管中的流体被加压到足以将密封件从其正常关闭状态移动到其打开状态的程度，从而使流体能够被泵送通过流体出口。单向阀31可以由活塞构件的第一端承载，用于控制流入和流出计量室的流体流。流体导管可以包括延伸穿过活塞构件的部分34，例如。其管腔。

4. 发明申请

WO2006097746A1 INHALATION DEVICES 审中-公开
标题翻译：吸入装置
公开(公告)号：WO2006097746A1
公开(公告)日：2006-09-21
申请号：PCT/GB2006/000965
申请日：2006-03-16
申请人： GLAXO GROUP LIMITED , LINTERN, Richard, David , RAND, Paul, Kenneth
发明人： LINTERN, Richard, David , RAND, Paul, Kenneth
IPC分类号： A61M15/00 , B65D83/14 , B05B11/00
CPC分类号： A61M15/009 , A61M15/0068 , B65D83/386
摘要： An inhaler comprising: a canister (5, 105) which comprises a body (23, 123) and a valve stem (25, 125) and an actuator comprising a main body (3, 103) receiving the canister (5, 105) and an actuating mechanism (9, 109) for actuating the canister (5, 105), wherein the actuating mechanism (9, 109) comprises a loading member (61, 161) which engages or is comprised in the canister (5, 105), and at least one actuating member (63a, b, 163a, b) which is depressible by a user to drive the loading member (61, 161) in an actuating direction from a rest position to an actuated position in which the canister (5, 105) is actuated to deliver medicament, wherein the at least one actuating member (63a, b, 163a, b) is a flexible element which has a first, flexed configuration when the loading member (61, 161) is in the rest position and, on depression, is extended in the actuating direction, such as to drive the loading member (61, 161) in the actuating direction from the rest position to the actuated position.
摘要翻译：一种吸入器，包括：罐（5,105），其包括主体（23,123）和阀杆（25,125）和致动器，所述致动器包括容纳所述罐（5,105）的主体（3,103）和用于致动所述罐（5,105）的致动机构（9,109），其中所述致动机构（9,109）包括接合或包括在所述罐（5,105）中的装载构件（61,161）以及至少一个致动构件（63a，b，163a，b），所述至少一个致动构件（63a，b，163a，b）可由使用者按压以在致动方向上从静止位置驱动到所述致动位置， 105）被致动以递送药物，其中所述至少一个致动构件（63a，b，163a，b）是柔性元件，当所述装载构件（61,161）处于静止位置时，所述柔性元件具有第一弯曲构造，在凹陷处，在致动方向上延伸，例如将驱动方向上的装载构件（61,161）从静止位置驱动到致动位置。

5. 发明申请

WO2006097756A1 INHALATION DEVICES 审中-公开
标题翻译：吸入装置
公开(公告)号：WO2006097756A1
公开(公告)日：2006-09-21
申请号：PCT/GB2006/000978
申请日：2006-03-16
申请人： GLAXO GROUP LIMITED , LINTERN, Richard, David , RAND, Paul, Kenneth
发明人： LINTERN, Richard, David , RAND, Paul, Kenneth
IPC分类号： A61M15/00 , B65D83/14
CPC分类号： A61M15/009 , A61M15/0026 , A61M15/007 , A61M15/0081 , A61M15/0096 , A61M15/08
摘要： An actuator for an inhaler for delivering medicament by inhalation, comprising: a housing (11) for receiving a canister (5) comprising a body (23) which defines a chamber containing medicament and a valve stem (25) which extends from the body (23); and a priming mechanism (7) for priming the actuator such as to be actuatable by a user, wherein the priming mechanism (7) comprises a support member (27) which includes a nozzle block (31) for receiving the valve stem (25) of the canister (5) and which is movable relative to the housing (11) between a first, inoperative position in which the canister (5) is inactuatable and a second, primed position in which the canister (5) is actuatable.
摘要翻译：一种用于通过吸入输送药物的吸入器的致动器，包括：用于容纳罐（5）的壳体（11），所述罐（5）包括限定含有药物的腔室的主体（23）和从所述主体延伸的阀杆（25） 23）; 以及用于使所述致动器起动以由用户致动的起动机构（7），其中所述起动机构（7）包括支撑构件（27），所述支撑构件包括用于接收所述阀杆（25）的喷嘴块（31）（5）的第一不工作位置，其中罐（5）不可操作的第一不工作位置和可致动罐（5）的第二起始位置之间相对于壳体（11）移动。

6. 发明申请

WO2009068877A1 A DISPENSING DEVICE 审中-公开
标题翻译：分配设备
公开(公告)号：WO2009068877A1
公开(公告)日：2009-06-04
申请号：PCT/GB2008/003954
申请日：2008-11-27
申请人： GLAXO GROUP LIMITED , LAMBLE, Ralph, George , PEARSON, Allen, John , RAND, Paul, Kenneth
发明人： LAMBLE, Ralph, George , PEARSON, Allen, John , RAND, Paul, Kenneth
IPC分类号： B05B11/00 , A61M15/08
CPC分类号： A61M15/08 , A61M15/0025 , A61M15/009 , B05B1/3436 , B05B11/0037 , B05B11/0067 , B05B11/3004 , B05B11/304 , B05B11/3046 , B05B11/3057 , B05B11/307 , B05B11/3074
摘要： The actuator mechanism has a first member (1420; 2420; 3420; 4420; 5420) mounted for movement in a predetermined direction and a second member (1425; 2425; 3425; 4425; 5425) pivotally mounted on the first member for pivotal movement in a predetermined pivotal sense. The actuator mechanism is adapted such that movement of the first member in the predetermined direction results in the second member moving therewith and pivoting in the predetermined pivotal sense and said pivotal movement of the second member in the predetermined pivotal sense results in the dispensing member moving from the first position to the second position.
摘要翻译：致动器机构具有安装成沿预定方向移动的第一构件（1420; 2420; 3420; 4420; 5420）和枢转地安装在第一构件上的第二构件（1425; 2425; 3425; 4425; 5425），用于枢转运动一个预定的关键意义。致动器机构适于使得第一构件沿预定方向的移动导致第二构件随之移动并且以预定的枢转方向枢转并且第二构件以预定的枢转方向的枢转运动导致分配构件从第一个位置到第二个位置。

7. 发明申请

WO2006097747A1 INHALATION DEVICES 审中-公开
标题翻译：吸入装置
公开(公告)号：WO2006097747A1
公开(公告)日：2006-09-21
申请号：PCT/GB2006/000966
申请日：2006-03-16
申请人： GLAXO GROUP LIMITED , PEARSON, Allen, John , RAND, Paul, Kenneth
发明人： PEARSON, Allen, John , RAND, Paul, Kenneth
IPC分类号： A61M15/00 , B65D83/14 , B05B11/00
CPC分类号： A61M15/009 , A61M15/0068 , B05B11/0037 , B05B11/3056 , B65D83/201 , B65D83/386
摘要： An inhaler for delivering medicament by inhalation comprises a canister (305) and an actuator comprising a housing (311) receiving the canister, and an actuation mechanism (309) for actuating the canister (305). The actuation mechanism (309) comprises a loading member (361) which is fitted to the head of the canister body (323) and includes a loading section (375) which is in use, acted upon to drive the loading member (361) in an actuating direction from a rest position to an actuated position in which the canister (305) is actuated to deliver medicament. The actuation mechanism further comprises at least one actuating member (363a, b) which is actuatable by a user to drive the loading member (361) in the actuating direction to the actuated position. The at least one actuating member (363a, b) is pivotally coupled to the housing (311) and comprises a gripping element (377) which is configured to be gripped and depressed by the user in actuating the canister (305).
摘要翻译：用于通过吸入输送药物的吸入器包括罐（305）和致动器，其包括容纳罐的壳体（311）和用于致动罐（305）的致动机构（309）。致动机构（309）包括装配到罐主体（323）的头部的装载构件（361），并且包括在使用中的装载部分（375），用于驱动装载构件（361）从静止位置到致动位置的致动方向，其中罐（305）被致动以输送药物。所述致动机构还包括至少一个致动构件（363a，b），所述至少一个致动构件可由使用者致动，以将所述加载构件（361）沿所述致动方向驱动到所述致动位置。所述至少一个致动构件（363a，b）枢转地联接到所述壳体（311）并且包括夹持元件（377），所述夹紧元件被构造成在使用者致动所述罐（305）时被使用者抓住并压下。

8. 发明申请

WO2006097753A1 INHALATION DEVICES 审中-公开
标题翻译：吸入装置
公开(公告)号：WO2006097753A1
公开(公告)日：2006-09-21
申请号：PCT/GB2006/000975
申请日：2006-03-16
申请人： GLAXO GROUP LIMITED , PEARSON, Allen, John , RAND, Paul, Kenneth
发明人： PEARSON, Allen, John , RAND, Paul, Kenneth
IPC分类号： A61M15/00 , A61M15/08 , B65D83/14 , B05B11/00
CPC分类号： A61M15/009 , A61M15/0025 , A61M15/007 , A61M15/08 , B05B11/0037 , B05B11/3056
摘要： An inhaler for delivering medicament by inhalation comprises (i) a canister (5) which comprises a body (23) which defines a chamber containing medicament and a valve stem (25) which extends from the body (23) and from which medicament is in use delivered on actuation of the canister (5), and (ii) an actuator. The actuator comprises a housing (11) in which the canister (5) is received, and an actuating mechanism (9) for actuating the canister (5). The actuating mechanism (9) comprises a loading member (61) which is fitted to or comprised in the body (23) of the canister (5), an actuating member (63) which is operable by a user to actuate the canister (5) to deliver medicament, and a drive member (65) which operably couples the loading member (61) and the actuating member (63) and is pivotally mounted, such as to be pivoted on operation of the actuating member (63) to engage and drive the loading member (61) from a first, rest position to a second, actuated position in which the canister (5) is actuated.
摘要翻译：用于通过吸入递送药物的吸入器包括（i）罐（5），其包括限定包含药物的腔室的主体（23）和从主体（23）延伸并从其中药物处于其中的阀杆（25）在罐（5）的致动时传送的使用，和（ii）致动器。致动器包括容纳罐（5）的壳体（11）和用于致动罐（5）的致动机构（9）。所述致动机构（9）包括装配到所述罐（5）的主体（23）中或包括在所述罐（5）的主体（23）中的装载构件（61），致动构件（63），其可由使用者操作以驱动所述罐）以及驱动构件（65），其可操作地连接所述加载构件（61）和所述致动构件（63）并被枢转地安装，以便在所述致动构件（63）的操作时枢转以接合和将加载构件（61）从第一静止位置驱动到第二致动位置，其中罐（5）被致动。

9. 发明申请

WO2005087299A1 A DISPENSING DEVICE 审中-公开
标题翻译：分配设备
公开(公告)号：WO2005087299A1
公开(公告)日：2005-09-22
申请号：PCT/GB2005/000926
申请日：2005-03-10
申请人： GLAXO GROUP LIMITED , ANDERSON, Gregor, John, McLennan , BRAND, Peter, John , COX, Mark, Anthony , CUDE, Ian , FARR, Philip, William , KELLY, Andrew, Michael , LINTELL, Daniel, Thomas, De Sausmarez , PEARSON, Allen, John , RAND, Paul, Kenneth
发明人： ANDERSON, Gregor, John, McLennan , BRAND, Peter, John , COX, Mark, Anthony , CUDE, Ian , FARR, Philip, William , KELLY, Andrew, Michael , LINTELL, Daniel, Thomas, De Sausmarez , PEARSON, Allen, John , RAND, Paul, Kenneth
IPC分类号： A61M15/00
CPC分类号： A61M15/00 , A61M11/04 , A61M15/0023 , A61M15/0025 , A61M15/0076 , A61M15/0081 , A61M15/009 , A61M15/0095 , A61M15/0096 , A61M2205/276 , A61M2205/6045
摘要： An inhaler is provided with a restricting member (6) to prevent unintentional actuation of the inhaler. Also provided is an inhaler with an extensible strap (2) joining a dust cap (5) to the housing (1) of an inhaler, the strap being particularly suited for use with inhalers that comprise a restricting member. The inhaler is useful, for example, in the treatment of asthma.
摘要翻译：吸入器设置有限制构件（6）以防止吸入器的意外致动。还提供了具有将防尘盖（5）连接到吸入器的壳体（1）的可伸长带（2）的吸入器，该带特别适用于包括限制构件的吸入器。吸入器例如用于治疗哮喘是有用的。

10. 发明申请

WO2007028992A1 AN INHALER 审中-公开
标题翻译：一个吸入器
公开(公告)号：WO2007028992A1
公开(公告)日：2007-03-15
申请号：PCT/GB2006/003307
申请日：2006-09-07
申请人： GLAXO GROUP LIMITED , PEARSON, Allen, John , RAND, Paul, Kenneth
发明人： PEARSON, Allen, John , RAND, Paul, Kenneth
IPC分类号： A61M15/00
CPC分类号： A61M15/009 , A61M15/0025 , A61M15/0076 , A61M15/0081 , A61M2205/276
摘要： An inhaler (70) is provided with a closure (5) which may be moved between a closed and open position in order to cover and uncover a mouthpiece (3). The closure (5) is associated with a revolvable element (6) comprising a restricting member (7). Movement of the closure (5) from the open position to the closed position causes the revolvable element (6) to revolve around an axis X thereby placing the restricting member (7) in a restricting position which restricts relative movement between a container unit (14) and the housing (1) such that unintentional actuation of the inhaler is prevented. The inhaler is useful, for example, in the treatment of asthma.
摘要翻译：吸入器（70）设置有封闭件（5），所述封闭件可以在闭合位置和打开位置之间移动，以覆盖和露出接口（3）。封闭件（5）与包括限制构件（7）的可旋转元件（6）相关联。闭合件（5）从打开位置移动到关闭位置使得可转动元件（6）围绕轴线X旋转，从而将限制件（7）放置在限制位置，限制位置限制容器单元（14））和壳体（1），使得防止吸入器的无意的致动。吸入器例如用于治疗哮喘是有用的。

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