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1. 发明申请

WO2012104733A3 SYSTEM AND METHOD FOR DETERMINING LOCATION AND ORIENTATION OF A DEVICE IN-VIVO 审中-公开
标题翻译：用于确定设备内部的位置和方向的系统和方法
公开(公告)号：WO2012104733A3
公开(公告)日：2013-01-03
申请号：PCT/IB2012000953
申请日：2012-02-01
申请人： GIVEN IMAGING LTD , IDDAN GAVRIEL J
发明人： IDDAN GAVRIEL J
IPC分类号： G01S5/18 , G01S5/30 , G01S11/16
CPC分类号： A61B8/0841 , A61B1/00158 , A61B1/041 , A61B5/065 , A61B5/073 , A61B8/52 , A61B8/54 , A61B17/00234
摘要： A system and method for determining location and orientation of an in-vivo device, with respect to an external system in which the device is located include a frame with external magnets attached thereon. An in-vivo device is inserted into the patient's body, which is placed within the system, and the external magnets apply magnetic forces on the in-vivo device. A radio beacon transmitter is attached to the frame for transmitting a radio pulse. The in-vivo device includes an ultrasonic transmitter for transmitting an ultrasonic signal, which is triggered by the radio pulse. At least three transponders are placed on the patient' s body, each transponder sending a first acoustic signal triggered by the radio pulse, and each sending a second acoustic signal triggered by the device's ultrasonic signal. At least three sonic detectors are located on the frame for detecting each of the transponders' first and second sonic signals, and a processor measures time of detection of the transponders' signals and thus calculates location of the device in frame coordinates, and in body coordinates.
摘要翻译：用于确定体内装置的相对于装置所在的外部系统的位置和取向的系统和方法包括附接有外部磁体的框架。将体内装置插入到放置在系统内的患者体内，外部磁体对体内装置施加磁力。无线电信标发射器附接到帧以发送无线电脉冲。体内装置包括用于发送由无线电脉冲触发的超声波信号的超声波发射器。至少三个转发器被放置在患者的身体上，每个应答器发送由无线电脉冲触发的第一声信号，并且每个发送由设备的超声信号触发的第二声信号。至少三个声波检测器位于框架上，用于检测每个应答器的第一和第二声音信号，并且处理器测量应答器信号的检测时间，并且因此以帧坐标计算设备的位置，并且在身体坐标。

2. 发明申请

WO2005062717A2 IN-VIVO SENSING DEVICE WITH DETACHABLE PART 审中-公开
标题翻译：具有可拆卸部分的体内感测装置
公开(公告)号：WO2005062717A2
公开(公告)日：2005-07-14
申请号：PCT/IL2004001183
申请日：2004-12-29
申请人： GIVEN IMAGING LTD , FRISCH MORDECHAI , GILAD ZVIKA , IDDAN GAVRIEL J , GLUKHOVSKY ARKADY , DAVIDSON TAL , GAT DANIEL , RABINOVITZ RAPHAEL
发明人： FRISCH MORDECHAI , GILAD ZVIKA , IDDAN GAVRIEL J , GLUKHOVSKY ARKADY , DAVIDSON TAL , GAT DANIEL , RABINOVITZ RAPHAEL
IPC分类号： A61B1/04 , A61B5/05
CPC分类号： A61B5/14546 , A61B1/00105 , A61B1/00156 , A61B1/041 , A61B5/073 , A61B5/416
摘要： A device and system for in-vivo sensing having a relatively heavy part and a relatively light part such that the heavy and light part may be temporarily attached in-vivo. Detachment of the heavy part may be provided at a predetermined location along a body lumen. The light part upon detachment of the heavy part may for example float within a body lumen.
摘要翻译：用于体内感测的装置和系统具有相对较重的部分和较轻的部分，使得重和轻的部分可以暂时附着在体内。可以在沿着体腔的预定位置处提供沉重部分的分离。轻质部分在沉重部分脱落时可以例如漂浮在体腔内。

3. 发明申请

WO2006070356A2 DEVICE, SYSTEM, AND METHOD FOR ADAPTIVE IMAGING 审中-公开
标题翻译：用于自适应成像的装置，系统和方法
公开(公告)号：WO2006070356A2
公开(公告)日：2006-07-06
申请号：PCT/IL2005001373
申请日：2005-12-22
申请人： GIVEN IMAGING LTD , IDDAN GAVRIEL J
发明人： IDDAN GAVRIEL J
IPC分类号： A61B1/06
CPC分类号： A61B1/041 , A61B1/00096 , A61B1/04
摘要： Device, system and method for adaptive imaging and adaptive in-vivo imaging. For example, an in-vivo imaging device may include a lens and a modifier to modify a physical property or an optical property of said lens.
摘要翻译：用于自适应成像和自适应体内成像的装置，系统和方法。例如，体内成像装置可以包括透镜和修饰物，以改变所述透镜的物理性质或光学性质。

4. 发明申请

WO02055984A3 A SYSTEM AND METHOD FOR DETERMINING IN VIVO BODY LUMEN CONDITIONS 审中-公开
标题翻译：用于确定体内乳液条件的系统和方法
公开(公告)号：WO02055984A3
公开(公告)日：2003-01-03
申请号：PCT/IL0200041
申请日：2002-01-16
申请人： GIVEN IMAGING LTD , IDDAN GAVRIEL J
发明人： IDDAN GAVRIEL J
IPC分类号： G03B15/00 , A61B1/00 , A61B1/273 , A61B5/00 , A61B5/07 , H04N7/18
CPC分类号： A61B5/073 , A61B1/041 , A61B1/2736 , A61B5/0084
摘要： The present invention relates to the field of in vivo diagnostics. More specifically, the present invention relates to a system and a method for the in vivo and in-situ detection of chemical and/or biological substances and for the in vivo detection of physical conditions in body lumens. Figure 1 shows interaction chambers (22), formed by a slab of glass (23), or between two pieces of glass (23A and 23B). A light source (24) is used to illuminate the interaction chambers, and an optical detector (26) detects changes within the interaction chambers. A reflector (25) may be utilized to re-direct light rays (27') from the light source (24) along an alternate path (27).
摘要翻译：本发明涉及体内诊断领域。更具体地说，本发明涉及一种用于体内和原位检测化学和/或生物物质的体系和方法，以及用于体内体内检测物理条件的方法。图1示出了由玻璃板（23）或两片玻璃（23A和23B）之间形成的相互作用室（22）。光源（24）用于照亮相互作用室，并且光学检测器（26）检测相互作用室内的变化。可以使用反射器（25）来重新引导来自光源（24）的光线（27'）沿着交替路径（27）。

5. 发明申请

WO2006070350A2 MOTOR FOR AN IN-VIVO DEVICE 审中-公开
标题翻译：电动马达装置
公开(公告)号：WO2006070350A2
公开(公告)日：2006-07-06
申请号：PCT/IL2005001351
申请日：2005-12-15
申请人： GIVEN IMAGING LTD , IDDAN GAVRIEL J , GILAD ZVIKA
发明人： IDDAN GAVRIEL J , GILAD ZVIKA
IPC分类号： A61B5/05
CPC分类号： A61B1/04 , A61B1/00156 , A61B1/041 , A61B5/061 , A61B5/064
摘要： The present invention may provide a system, method and device containing a motor. The motor may propel an in-vivo device by rotating a propeller situated for example outside of an outer shell of such device with an electromagnetic field generated by for example a plurality of electrical coils situated for example within such device.
摘要翻译：本发明可以提供一种包含电动机的系统，方法和装置。马达可以通过旋转位于例如位于这种装置的外壳外部的螺旋桨与例如位于这样的装置内的多个电线圈产生的电磁场来驱动体内装置。

6. 发明申请

WO2004086434A3 MAGNETIC SWITCH FOR USE IN A SYSTEM THAT INCLUDES AN IN-VIVO DEVICE, AND A METHOD OF USE THEREOF 审中-公开
标题翻译：用于包含体内装置的系统中的磁性开关及其使用方法
公开(公告)号：WO2004086434A3
公开(公告)日：2004-12-09
申请号：PCT/IL2004000280
申请日：2004-03-28
申请人： GIVEN IMAGING LTD , IDDAN GAVRIEL J
发明人： IDDAN GAVRIEL J
IPC分类号： A61B1/05 , A61B5/07 , H04N9/47
CPC分类号： A61B1/041 , A61B1/00036 , A61B1/00144 , A61B5/07
摘要： A switch such as a normally closed MEMS switch may be used in an in-vivo device to alter a mode or operation; for example, to disconnect the power unit from electrical circuitry during storage of the in-vivo device by introducing a magnetic field in the proximity of the in-vivo device. The in-vivo device may be powered by removing the magnetic field upon use. Other switches, such as normally open switches, or switches including multiple sets of leads, having multiple functionality, may be used. A packaging generating a magnetic field may operate the switch when the device is in the packaging.
摘要翻译：诸如常闭MEMS开关的开关可用于体内装置中以改变模式或操作; 例如通过在体内装置附近引入磁场来在体内装置的存储期间断开电力单元与电路的连接。体内装置可以通过在使用时去除磁场来供电。可以使用其他开关，例如常开开关，或者包括具有多个功能的多组引线的开关。当设备处于包装中时，产生磁场的包装可以操作开关。

7. 发明申请

WO2004096008A2 PANORAMIC FIELD OF VIEW IMAGING DEVICE 审中-公开
标题翻译：全景视觉成像装置
公开(公告)号：WO2004096008A2
公开(公告)日：2004-11-11
申请号：PCT/IL2004000367
申请日：2004-05-02
申请人： GIVEN IMAGING LTD , IDDAN GAVRIEL J , LEVY DAPHNA , RUBEY KEVIN , FRISCH MORDECHAI
发明人： IDDAN GAVRIEL J , LEVY DAPHNA , RUBEY KEVIN , FRISCH MORDECHAI
IPC分类号： A61B20060101 , A61B1/05 , A61B1/06 , A61B6/00 , H04N5/225 , A61B
CPC分类号： A61B1/041 , A61B1/0005 , A61B1/00181 , A61B1/00183 , A61B1/05 , A61B1/0623 , G02B23/2423 , G02B23/2484 , H04N2005/2255
摘要： An in vivo imaging device with a curved reflective element and for example a concave portion of an outer shell of such device. Such curved reflective element may for example reflect onto an image sensor light rays from an object where such light rays before reflection are substantially parallel to the plane of the image sensor. An in vivo imaging device with a reflective surface situated at an angle to an image sensor of such imaging device. Such an angle may be for example a 45 degree angle so that light rays that are substantially parallel to a plain of an image sensor of an imaging device may for example be reflected by the reflective surface onto the image sensor.
摘要翻译：一种具有弯曲反射元件并且例如这种装置的外壳的凹部的体内成像装置。这种弯曲的反射元件可以例如反射到图像传感器上，来自物体的光线，其中反射之前的这种光线基本上平行于图像传感器的平面。一种体内成像装置，其具有与这种成像装置的图像传感器成角度的反射表面。这样的角度可以是例如45度角，使得基本上平行于成像装置的图像传感器的平面的光线例如可以被反射表面反射到图像传感器上。

8. 发明申请

WO2004028336A3 REDUCED SIZE IMAGING DEVICE 审中-公开
标题翻译：减小尺寸成像装置
公开(公告)号：WO2004028336A3
公开(公告)日：2004-05-21
申请号：PCT/IL0300785
申请日：2003-09-30
申请人： GIVEN IMAGING LTD , GILAD ZVIKA , IDDAN GAVRIEL J
发明人： GILAD ZVIKA , IDDAN GAVRIEL J
IPC分类号： A61B20060101 , A61B1/05 , A61B5/03 , A61B6/00
CPC分类号： A61B1/041 , A61B1/051 , A61B1/0607 , A61B1/0676 , A61B1/0684 , A61B5/036
摘要： A reduced diameter in vivo imaging device, such as a swallowable imaging capsule. The imaging device includes a first circuit board (107) configured for accommodating at least an image sensor (107), and a second circuit board (112), which is in electrical communication with the first circuit board and which extends substantially perpendicularly from the bottom surface of the first circuit board.
摘要翻译：直径减小的体内成像装置，例如吞咽成像胶囊。该成像装置包括被配置为容纳至少一个图像传感器（107）的第一电路板（107）和与第一电路板电连通且从底部基本上垂直延伸的第二电路板（112）第一个电路板的表面。

9. 发明申请

WO2004036803A2 DEVICE, SYSTEM AND METHOD FOR TRANSFER OF SIGNALS TO A MOVING DEVICE 审中-公开
标题翻译：用于将信号转移到移动装置的装置，系统和方法
公开(公告)号：WO2004036803A2
公开(公告)日：2004-04-29
申请号：PCT/IL0300834
申请日：2003-10-15
申请人： GIVEN IMAGING LTD , IDDAN GAVRIEL J
发明人： IDDAN GAVRIEL J
IPC分类号： A61B5/00 , H04L
CPC分类号： A61B1/041 , A61B1/00016 , A61B1/00029 , A61B1/00034 , A61B5/0013 , A61B2560/0219
摘要： A system for transfer of a signal, such as an energizing signal, to a transmitting in vivo sensing device (20). The in vivo device (20) includes at least one signal transmitter (24) and at least one signal receiving unit (27). The system includes an external phased array antenna (22). The phased array antenna (22) receives a signal from the sensing device (20) and then transmits a signal to the device (20) phased in the reverse order to that of receipt of the signal from the sensing device (20).
摘要翻译：一种用于将诸如激励信号之类的信号传输到发射体内感测设备（20）的系统。体内装置（20）包括至少一个信号发射器（24）和至少一个信号接收单元（27）。该系统包括一个外部相控阵天线（22）。相控阵天线（22）从感测装置（20）接收信号，然后以与从感测装置（20）接收信号相反的顺序将信号发送到装置（20）。

10. 发明申请

WO2006070368A3 METHOD AND SYSTEM FOR TREATMENT OF AN IN VIVO SITE 审中-公开
标题翻译：用于治疗个体生物体的方法和系统
公开(公告)号：WO2006070368A3
公开(公告)日：2007-06-14
申请号：PCT/IL2005001395
申请日：2005-12-28
申请人： GIVEN IMAGING LTD , IDDAN GAVRIEL J
发明人： IDDAN GAVRIEL J
IPC分类号： A61B5/05 , A61B6/00 , A61B8/00 , A61B8/12 , A61B8/14 , A61M25/00
CPC分类号： A61B1/00188 , A61B1/00016 , A61B1/00147 , A61B1/00183 , A61B1/041 , A61B5/073 , A61B5/1076 , A61B5/14539 , A61B5/6882
摘要： A system and method may provide treatment of an in vivo site, for example, using an in vivo imaging device such as an immobilized imaging device, a receiver and a generator, for example an ultrasound generator, an electro-magnetic energy generator or a radiation generator.
摘要翻译：系统和方法可以提供体内部位的治疗，例如使用诸如固定的成像装置，接收器和发生器的体内成像装置，例如超声波发生器，电磁能量发生器或辐射发电机。

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