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1. 发明申请

WO2022096642A1 PLATE CLEANING DEVICE 审中-公开
公开(公告)号：WO2022096642A1
公开(公告)日：2022-05-12
申请号：PCT/EP2021/080756
申请日：2021-11-05
申请人： F. HOFFMANN-LA ROCHE AG , HOFFMANN-LA ROCHE INC.
发明人： CARRASCO, Edgar Ernesto , SCHMIDLI, Dieter , STEINER, Roger , VOELKLE, Joerg
IPC分类号： C12M1/32 , C12M1/00
摘要： A plate cleaning device (1) for cleaning a clamp plate of a fermenter, wherein the clamp plate has a plurality of receptacles each configured to hold a bioreactor vessel, and at least one conduit with a conduit opening per receptacle. The device comprises a plate seat member (3), a cover member (2), a plurality of valve units (4), a first fluid terminal (71), a second fluid terminal (74) and a control unit (9). The plate seat member (3) is configured to hold the clamp plate (6) in a predefined position and orientation. The cover member (2) is configured to close the plate seat member (3) such that the clamp plate (6) is tightly enclosed by the plate seat member (3) and the cover member (2). The plurality of valve units (4) is configured to be coupled to the cover member (2) such that at least one valve unit (4) is associated to each of the conduit openings (62) of the clamp plate (6). The first fluid terminal (71) is configured to receive a first fluid container and the second fluid terminal (74) to receive a second fluid container. The cover member (2) is equipped with channels each having a first open end and a second open end. Each of the first open ends of the channels of the cover member (2) is positioned to be connected to one of the conduit openings (62) of the clamp plate (6). The valve units (4) are configured to be coupled to the second open ends of the channels of the plate such that all of the at least one conduit openings (62) per receptacle are associated to one valve(4). The first fluid terminal (71) and the second fluid terminal (74) are coupled to each of the valve units (4). The control unit (9) is configured to selectively connect the first fluid terminal (71) and the second fluid terminal (74) to the second open ends of the channels of the cover member (2).

2. 发明申请

WO2022090399A1 MICROPLATE SYSTEM AND CONTAINMENT 审中-公开
公开(公告)号：WO2022090399A1
公开(公告)日：2022-05-05
申请号：PCT/EP2021/079994
申请日：2021-10-28
申请人： F. HOFFMANN-LA ROCHE AG , HOFFMANN-LA ROCHE INC.
发明人： BURRI, Sven , CANESSO, Rolf , HOFER, Pascal Markus , LUZIO, Jonas , SCHMIDLI, Dieter , ZUMSTEIN, Thomas
IPC分类号： B01L3/00 , B01L9/06
摘要： A microplate system (1) comprising a microplate (2) and a plurality of containments (3).The microplate (2) has a length in a range between about 127 mm and about 129 mmand a width in a range between about 84 mm and about 86 mm. The microplate (2) has 384 or 1536 receptacles (21). Each receptacle (21) of the microplate (2) extends through the microplate (2) such that it has a first open end and a second open end. Each receptacle (21) of the microplate (2) forms a seat to hold one of the plurality of containments (3). Each of the plurality of containments (3) comprises a cap (32) and a tube (31) shaped to be held in the seat of one of the receptacles (21) of the microplate (2). The plurality of containments (3) and the receptacles (21) of the microplate (2) are shaped such that, in order to be arranged in the microplate (2), each of the plurality of containments (3) is introducible through the first open end of the one of the receptacles (21) into the one of the receptacles (21) until it is held in the seat (212) of the one of the receptacles (21). The tube (31) and the cap (32) of each of the containments (3) are configured to be multiply connected to each other and disconnected from each other.

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