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1. 发明申请

WO2011053462A1 FLEXIBLE IMPLANTS HAVING INTERNAL VOLUME SHIFTING CAPABILITIES FOR TREATING OBSTRUCTIVE SLEEP APNEA 审中-公开
标题翻译：具有内部容积移动能力的柔性植入物用于治疗阻塞性睡眠APNEA
公开(公告)号：WO2011053462A1
公开(公告)日：2011-05-05
申请号：PCT/US2010/052644
申请日：2010-10-14
申请人： ETHICON, INC. , ROUSSEAU, Robert, A.
发明人： ROUSSEAU, Robert, A.
IPC分类号： A61F5/56
CPC分类号： A61F5/566
摘要： An implant for treating obstructive sleep apnea includes a first chamber (26) containing an incompressible fluid (34), a second chamber (28a, b) containing a compressible fluid (36a, b), and a flexible diaphragm (30, 32) separating the first and second chambers. The incompressible fluid is in communication with the compressible fluid via the flexible diaphragm. The first chamber has a first volume that remains constant in response to an external force applied upon the implant and the second chamber has a second volume that is changeable when the external force is applied upon the implant. The flexible diaphragm is extendible into the second chamber for reducing the second volume of the second chamber and compressing the compressible fluid within the second chamber. The compressible fluid within the second chamber provides less resistance to flexing during initial flexing of the implant and more resistance to flexing during further flexing of the implant.
摘要翻译：用于治疗阻塞性睡眠呼吸暂停的植入物包括含有不可压缩流体（34）的第一腔室（26），包含可压缩流体（36a，b）的第二腔室（28a，b）第一和第二室。不可压缩流体通过柔性隔膜与可压缩流体连通。第一腔室具有响应于施加在植入物上的外力而保持恒定的第一体积，并且第二腔室具有当外力施加在植入物上时可变的第二体积。柔性膜片可延伸到第二腔室中，用于减小第二腔室的第二体积并压缩第二腔室内的可压缩流体。第二室内的可压缩流体在植入物的初始屈曲期间提供更小的抗弯曲性，并且在植入物的进一步弯曲期间具有更大的抗弯曲能力。

2. 发明申请

WO2010074861A1 SURGICAL SUTURES HAVING COLLAPSIBLE TISSUE ANCHORING PROTRUSIONS AND METHODS THEREFOR 审中-公开
标题翻译：具有可拆卸组织锚固支架的外科手术及其方法
公开(公告)号：WO2010074861A1
公开(公告)日：2010-07-01
申请号：PCT/US2009/065350
申请日：2009-11-20
申请人： ETHICON, INC. , NAWROCKI, Jesse, G. , LINDH, David, C. , ROUSSEAU, Robert, A.
发明人： NAWROCKI, Jesse, G. , LINDH, David, C. , ROUSSEAU, Robert, A.
IPC分类号： A61B17/06 , A61B17/00
CPC分类号： A61B17/06166 , A61B2017/00004 , A61B2017/00526 , A61B2017/00893 , A61B2017/00951 , A61B2017/06176 , A61B2017/06185
摘要： A surgical suture (100) includes a shaft (102) having a leading end (104), a trailing end (106), and an outer surface (114) extending between the leading and trailing ends. The surgical suture includes a plurality of flexible protrusions (108) extending from the shaft, and a lumen (960) extending between the leading and trailing ends of the shaft. The shaft (902) includes a plurality of openings (975) formed in the outer surface thereof that are in communication with the lumen. The shaft includes a first axial opening at the leading end thereof in communication with the lumen and a second axial opening at the trailing end thereof in communication with the lumen. A flowable material may be disposed in the lumen. After the surgical suture is implanted, the flowable material is adapted to pass from the lumen and through the plurality of openings in the outer surface of the shaft for contacting tissue surrounding the suture.
摘要翻译：手术缝合线（100）包括具有前端（104），后端（106）和在前端和后端之间延伸的外表面（114）的轴（102）。手术缝合线包括从轴延伸的多个柔性突起（108）和在轴的前端和后端之间延伸的内腔（960）。轴（902）包括形成在其外表面中的与内腔连通的多个开口（975）。轴包括在其前端处与内腔连通的第一轴向开口和在其后端处与腔连通的第二轴向开口。可流动的材料可以设置在内腔中。在植入手术缝合线之后，可流动材料适于从内腔通过并穿过轴的外表面中的多个开口，用于接触缝合线周围的组织。

3. 发明申请

WO2010011532A1 COLLAPSIBLE BARBED SUTURES HAVING REDUCED DRAG AND METHODS THEREFOR 审中-公开
标题翻译：具有减少拖曳的可收缩的ED ED AG。。。。。。。。
公开(公告)号：WO2010011532A1
公开(公告)日：2010-01-28
申请号：PCT/US2009/050540
申请日：2009-07-14
申请人： ETHICON, INC. , ROUSSEAU, Robert, A.
发明人： ROUSSEAU, Robert, A.
IPC分类号： A61B17/06
CPC分类号： A61B17/06166 , A61B2017/00526 , A61B2017/06176
摘要： A barbed suture (120) includes a flexible thread (122) having a core with a leading end (136), a trailing end (138), and a central axis (124). -The barbed suture (120) includes a first flexible flap (130) connected to the core, the first flap extending between the leading and trailing ends of the core, and a second flexible flap (134) connected to the core, the second flap (134) extending between the leading and trailing ends (136,138) of the core. The flexible flaps (130,134) and the core have an S-shaped profile when viewed in cross- section. The barbed suture (120) includes first and second slots (140,150) formed in the respective first and second flaps (130,134) for dividing the flaps (130,134) into first and second barbs (146,156) projecting from the core, whereby each slot (140,150) extends outwardly from the core and rearwardly toward the trailing end (138) of the core.
摘要翻译：有倒刺的缝合线（120）包括具有带有前端（136）的芯部，后端（138）和中心轴线（124）的柔性线（122）。 - 有倒刺的缝合线（120）包括连接到所述芯的第一柔性翼片（130），所述第一翼片在所述芯的前端和后端之间延伸，以及连接到所述芯的第二柔性翼片（134），所述第二翼片（134），其在所述芯的前端和后端（136,138）之间延伸。当横截面看时，柔性翼片（130,134）和芯具有S形轮廓。有倒勾的缝合线（120）包括形成在相应的第一和第二襟翼（130,134）中的第一和第二狭槽（140,150），用于将襟翼（130,134）分成从芯部突出的第一和第二倒钩（146,156），由此每个狭槽（140,150 ）从芯部向外延伸并向后延伸到芯部的尾端（138）。

4. 发明申请

WO2011059629A1 TONGUE SUSPENSION SYSTEM WITH HYOID-EXTENDER FOR TREATING OBSTRUCTIVE SLEEP APNEA 审中-公开
标题翻译：用于治疗阻塞性睡眠障碍的超声剂延迟系统
公开(公告)号：WO2011059629A1
公开(公告)日：2011-05-19
申请号：PCT/US2010/052649
申请日：2010-10-14
申请人： ETHICON, INC. , WEADOCK, Kevin , ROUSSEAU, Robert, A. , LINDH, David, C.
发明人： WEADOCK, Kevin , ROUSSEAU, Robert, A. , LINDH, David, C.
IPC分类号： A61F5/56
CPC分类号： A61F5/566
摘要： A system for treating obstructive sleep apnea includes a first element (20) implantable in a tongue and a second element (30) implantable between muscle planes of an inf ramandibular region. The second element has a first end coupled with the first element and a second end coupled with a hyoid bone for preventing the base of the tongue from collapsing against an opposing pharyngeal wall during sleep. The first and second implantable elements have outer surfaces that are substantially impermeable to tissue in-growth to allow for post-surgical adjustment or removal, if necessary. The first implantable element is elongated and includes a first end, a second end, and a center section located between the first and second ends. The center section is implantable in the tongue, and the first and second ends of the first implantable element are advanceable beneath the tongue for being coupled with the anterior end of the second implantable element.
摘要翻译：用于治疗阻塞性睡眠呼吸暂停的系统包括可植入舌头的第一元件（20）和可植入在腋下颌区域的肌肉平面之间的第二元件（30）。第二元件具有与第一元件相结合的第一端和与舌骨相连的第二端，用于防止舌头的基部在睡眠期间与相对的咽壁塌陷。第一和第二可植入元件具有外表面，该表面基本上不可渗透组织生长以允许后手术调整或移除，如果需要的话。第一可植入元件是细长的并且包括第一端，第二端和位于第一端和第二端之间的中心部分。中心部分可植入舌部，并且第一可植入元件的第一和第二端可在舌下方前进，以与第二可植入元件的前端相连。

5. 发明申请

WO2010096277A1 MAGNETIC IMPLANTS AND METHODS FOR TREATING AN OROPHARYNGEAL CONDITION 审中-公开
标题翻译：磁性植入物和治疗恶性病症的方法
公开(公告)号：WO2010096277A1
公开(公告)日：2010-08-26
申请号：PCT/US2010/023152
申请日：2010-02-04
申请人： ETHICON, INC. , ROUSSEAU, Robert, A. , WEADOCK, Kevin, S. , SUNG, An-Amin, Jason
发明人： ROUSSEAU, Robert, A. , WEADOCK, Kevin, S. , SUNG, An-Amin, Jason
IPC分类号： A61F5/56 , A61N2/06 , A61N2/00
CPC分类号： A61F5/566 , A61F5/56 , A61F2210/009 , A61N2/06
摘要： Magnetic devices and implantation methods are provided for use in the treatment of obstructive sleep apnea. The devices include a sheet- like element having ferromagnetic qualities. The device may also include a permanent magnet attached to the sheet-like element by magnetic forces. The devices are implanted in soft tissue surrounding the airway and in tissue space beneath the pharyngeal wall to exert forces on and/or change the shape of the soft tissue. The magnetic devices may also include a bladder containing a magnetorheological fluid that stiffens soft tissue when exposed to a magnetic field.
摘要翻译：提供磁性装置和植入方法用于治疗阻塞性睡眠呼吸暂停。这些装置包括具有铁磁性质的片状元件。该装置还可以包括通过磁力附着到片状元件的永磁体。将装置植入围绕气道的软组织和咽壁下方的组织空间中以施加力和/或改变软组织的形状。磁性装置还可以包括含有磁流变流体的囊状物，当暴露于磁场时，该液体硬化软组织。

6. 发明申请

WO2010051195A1 IMPLANT SYSTEMS AND METHODS FOR TREATING OBSTRUCTIVE SLEEP APNEA 审中-公开
标题翻译：植入系统和治疗阻塞性睡眠障碍的方法
公开(公告)号：WO2010051195A1
公开(公告)日：2010-05-06
申请号：PCT/US2009/061455
申请日：2009-10-21
申请人： ETHICON, INC. , LINDH, David, C. , ROUSSEAU, Robert, A. , WEADOCK, Kevin, S.
发明人： LINDH, David, C. , ROUSSEAU, Robert, A. , WEADOCK, Kevin, S.
IPC分类号： A61F2/20
CPC分类号： A61F5/566
摘要： A method of treating obstructive sleep apnea includes providing an elongated element having a central buttress area and first and second arms extending from opposite ends of the central buttress area. The method includes implanting the central buttress area in a tongue so that a longitudinal axis of the central buttress area intersects an anterior-posterior axis of the tongue. The first and second arms are advanced through the tongue until the first and second arms engage inframandibular musculature. Tension is applied to the first and second arms for pulling the central buttress area toward the inframandibular musculature for moving a posterior surface of the tongue away from an opposing surface of a pharyngeal wall. The first and second arms are anchored to the inframandibular musculature for maintaining a space between the posterior surface of the tongue and the opposing surface of the pharyngeal wall.
摘要翻译：治疗阻塞性睡眠呼吸暂停的方法包括提供具有中心支撑区域的细长元件和从中心支撑区域的相对端部延伸的第一和第二臂。该方法包括将中心支撑区域植入舌部，使得中心支撑区域的纵向轴线与舌头的前后轴线相交。第一和第二臂通过舌头前进，直到第一和第二臂与下颌下肌肉组织接合。张力被施加到第一和第二臂以将中央支撑区域拉向下颌下肌肉组织，以将舌的后表面远离咽壁的相对表面移动。第一和第二臂被锚固到下颌骨肌肉组织，以保持舌的后表面和咽壁的相对表面之间的空间。

7. 发明申请

WO2010019376A2 METHODS AND DEVICES FOR TREATMENT OF OBSTRUCTIVE SLEEP APNEA 审中-公开
标题翻译：用于治疗阻塞性睡眠障碍的方法和装置
公开(公告)号：WO2010019376A2
公开(公告)日：2010-02-18
申请号：PCT/US2009/051921
申请日：2009-07-28
申请人： ETHICON, INC. , ROUSSEAU, Robert, A. , WEADOCK, Kevin, S.
发明人： ROUSSEAU, Robert, A. , WEADOCK, Kevin, S.
IPC分类号： A61F5/56
CPC分类号： A61F5/56 , A61F5/566
摘要： A pharyngeal retractor device and implantation methods are provided for use in the treatment of obstructive sleep apnea. The device includes a retracting element and a tissue engaging element that promotes tissue ingrowth around or onto the retracting element. The device is implanted in tissue space beneath the pharyngeal wall to alter the shape of the wall. The device may be implanted through the oral cavity alone or by using a trocar or a hand-held delivery system to deliver the device through the pharyngeal wall. Alternatively, the device may be implanted using an open, direct visualization approach from the side of a patient's neck.
摘要翻译：提供咽收缩器装置和植入方法用于治疗阻塞性睡眠呼吸暂停。该装置包括回缩元件和组织接合元件，其促进组织向内生长在收缩元件周围或上。该装置植入咽壁下方的组织空间以改变壁的形状。该装置可以单独地通过口腔植入，或者通过使用套管针或手持递送系统将装置输送通过咽壁。或者，可以使用来自患者颈部侧面的开放的直接可视化方法来植入该装置。

8. 发明申请

WO2005018474A1 SURGICAL WOUND CLOSURE DEVICE 审中-公开
标题翻译：手术闭合装置
公开(公告)号：WO2005018474A1
公开(公告)日：2005-03-03
申请号：PCT/US2004/026215
申请日：2004-08-13
申请人： ETHICON, INC. , ROUSSEAU, Robert, A. , SUNG, An-Min, Jason
发明人： ROUSSEAU, Robert, A. , SUNG, An-Min, Jason
IPC分类号： A61B19/08
CPC分类号： A61F13/023 , A61B17/085 , A61F13/0206 , A61F13/0209 , A61F13/022 , A61F13/0223 , A61F13/0259 , A61F2013/0057
摘要： One embodiment includes a surgical wound closure device comprising a substrate having a proximal surface and a distal surface; a drape having a proximal surface and a distal surface, and being disposed proximally to said substrate; and an adhesive layer having a proximal surface and a distal surface; said drape being disposed releasably adherently to said distal surface of said adhesive layer.
摘要翻译：一个实施例包括外科伤口闭合装置，其包括具有近端表面和远侧表面的基底; 具有近侧表面和远侧表面的盖布，并且被布置在所述基底的近侧; 以及具有近端表面和远端表面的粘合剂层; 所述盖布可剥离地贴合在所述粘合剂层的所述远端表面上。

9. 发明申请

WO2013048901A1 MODULAR TISSUE SECUREMENT SYSTEMS 审中-公开
标题翻译：模块化组织安全系统
公开(公告)号：WO2013048901A1
公开(公告)日：2013-04-04
申请号：PCT/US2012/056577
申请日：2012-09-21
申请人： ETHICON, INC. , LINDH, David , ROUSSEAU, Robert, A.
发明人： LINDH, David , ROUSSEAU, Robert, A.
IPC分类号： A61B17/06
CPC分类号： A61B17/0485 , A61B17/06 , A61B17/06004 , A61B17/06066 , A61B17/06109 , A61B17/06166 , A61B17/06195 , A61B2017/06019 , A61B2017/06057 , A61B2017/06176 , A61F5/566
摘要： A system and method are disclosed for the securement of tissue and in particular for placement of a tongue base suspension fiber for the treatment of obstructive sleep apnea. The system incorporates disposable connectors with releasable needles to facilitate the placement of fibers with minimal increase in suture site dilation or trauma.
摘要翻译：公开了用于固定组织，特别是用于放置用于治疗阻塞性睡眠呼吸暂停的舌基悬浮纤维的系统和方法。该系统包括具有可释放针的一次性连接器，以便于缝合位置扩张或创伤的增加最小化的纤维放置。

10. 发明申请

WO2011075387A1 FLUID FILLED IMPLANTS FOR TREATING MEDICAL CONDITIONS 审中-公开
标题翻译：用于治疗医疗条件的流体填充植入物
公开(公告)号：WO2011075387A1
公开(公告)日：2011-06-23
申请号：PCT/US2010/059673
申请日：2010-12-09
申请人： ETHICON, INC. , ROUSSEAU, Robert, A.
发明人： ROUSSEAU, Robert, A.
IPC分类号： A61F2/02 , A61F2/20
CPC分类号： A61F2/20 , A61F2/02 , A61F5/0013 , A61F2250/0003
摘要： An implant for treating medical disorders includes a first chamber having a flexible outer layer that surrounds a flexible inner layer, a second chamber in communication with the first chamber, and a fluid transfer assembly adapted for transferring fluid between the second chamber and the first chamber for selectively modifying the rigidity of the first chamber. The implant includes at least one restraining element in contact with the flexible outer and inner layers for at least partially restricting volume expansion of the first chamber as the fluid is transferred into the first chamber. The first chamber is adapted to become more rigid as the fluid is transferred into the first chamber and more flexible as the fluid is removed from the first chamber. The first chamber is implantable within the soft tissue of a patient such as a tongue, soft palate, pharyngeal wall, urinary tract, rectum, trachea, or stomach.
摘要翻译：用于治疗医学病症的植入物包括具有包围柔性内层的柔性外层的第一腔室，与第一腔室连通的第二腔室，以及适于在第二腔室和第一腔室之间传送流体的流体传送组件，选择性地改变第一室的刚度。所述植入物包括与所述柔性外层和内层接触的至少一个限制元件，用于当所述流体被转移到所述第一室中时至少部分地限制所述第一室的体积膨胀。随着流体被转移到第一腔室中，第一腔室适于变得更刚性，并且当流体从第一腔室移除时，第一腔室更柔性。第一腔室可植入患者的软组织内，例如舌头，软腭，咽壁，尿道，直肠，气管或胃。

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