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    • 1. 发明申请
    • POLYMERIZABLE COMPOSITION AND THE APPLICATION THEREOF AS A COUPLING AGENT
    • 可聚合组合物及其作为LIABILITIZER的用途
    • WO9924477B1
    • 1999-06-24
    • PCT/EP9807092
    • 1998-11-06
    • ESPE DENTAL AGMAY ROBERTMIKULLA MARKUSBISSINGER PETER
    • MAY ROBERTMIKULLA MARKUSBISSINGER PETER
    • A61K6/00A61K6/083C08F2/46C08F20/10C08F220/26C08F222/06C08L33/04C09D4/00C09D4/02C09J4/02C09J4/06C08F8/14C09D4/06
    • A61K6/0017A61K6/0023C08F220/26C08F222/06C08L33/00
    • The invention relates to a polymerizable, cross-linkable composition which contains: (A) 1 - 99.99 wt. % of at least one conversion product of OH-functional (meth)acrylates with (i) oligomers from unsaturated rings or heterocyclic rings and maleic anhydride and/or with (ii) at least one ring-shaped polycarboxylic acid with at least 4 ring-carbon atoms and/or the anhydrides thereof with a saturated ring system, at least 4 carboxyl groups, and 0 or 1 heterocyclic ring atoms from the group N, O, S, whereby at least one carboxyl group and/or anhydride group of the above described substance groups is reacted with unsaturated polymerizable groups; (B) 0 to 98.99 wt. % of one or more polymerizable, unsaturated organic compounds with at least one CH2=C(R10)-COO-group, whereby R10 represents H or methyl; (C) 0.01 to 5 wt. % initiators and optional activators; (D) 0 to 90 wt. % common solvents; (E) 0 to 90 wt. % common fillers, pigments, thixotropy auxiliary agents, softening agents, diluting agents, rigidifying monomers, free-radical scavengers, stabilizing agents, and other auxiliary agents. The given wt. % refers to the sum of all components (A) to (E). The composition is suited for bonding, casting or coating substrates and is especially suited as dental coupling agents, dental filling materials, dental cements, or dental sealers in the fields of dentistry and dental technology.
    • 本发明涉及从1聚合性,交联性组合物,包含(A)〜99.99重量OH-官能的(甲基)中的至少一种反应产物与选自不饱和环或杂环和马来酸酐和/或(i)低聚物丙烯酸酯的% 与(ii)至少一个环形多元羧酸与至少4个环碳原子和/或它们的酸酐与饱和环体系和至少四个羧基基团以及选自N,O,S为0或1的杂环原子,其中至少一个羧基和/或酸酐 表示的化合物的上述基团与不饱和可聚合基团,(B)0〜98.99重量的一种或多种可聚合的%,具有至少一个CH 2 = C(R 10)-COO基团,其中R10 = H或不饱和的有机化合物进行反应 是甲基,(C)0.01〜5重量%的引发剂和任选的活化剂(d)0至90重量%的常规溶剂(E)0至90重量%的填料习惯 含有颜料,触变助剂,增塑剂,稀释剂,刚性化的单体,自由基清除剂,稳定剂,其他助剂,与所述重量的所述指示.-%在各情况下是指所有成分(A)至(E)的总和。 该组合物是适合用于胶粘,在牙科或牙科领域浇铸或涂覆基材,特别是,作为一个牙科粘合促进剂,牙科粘合性填充材料,牙科用水泥粘合性或牙科密封剂。
    • 3. 发明申请
    • INHALER
    • WO2010040779A3
    • 2010-07-01
    • PCT/EP2009063038
    • 2009-10-07
    • VECTURA DELIVERY DEVICES LTDSARKAR MATTHEWMAY ROBERTTWEEDIE ALANHARDMAN PAUL
    • SARKAR MATTHEWMAY ROBERTTWEEDIE ALANHARDMAN PAUL
    • A61M15/00
    • A61M15/0045A61M11/003A61M15/0021A61M15/0036A61M15/0051A61M2202/064A61M2206/16
    • An inhaler (1) for producing an inhalable aerosol of powdered medicament is disclosed. The inhaler (1) comprises an aerosolising device having a cyclone chamber (45) of substantially circular cross-section, inlet (24) and outlet (25) ports at opposite ends of the chamber (45) for the flow of drug laden air through the chamber (45) between said ports (24, 25) and, a bypass air inlet (46) for the flow of clean air into the chamber (45). The bypass air inlets (46) are configured so that air entering the chamber (45) through said inlet (46) forms a cyclone in the chamber (45) that interacts with the drug laden air flowing between the inlet (24) and outlet (25) ports. The inhaler (1) may have a tapered drug laden air flow conduit (70) to accelerate the flow prior to entry into the chamber (45) and/or an impaction element (81, 84, 92, 105) to deagglomerate drug particles.
    • 公开了一种用于产生粉末状药物的吸入性气溶胶的吸入器(1)。 吸入器(1)包括雾化装置,其具有基本上圆形横截面的旋风室(45),在室(45)的相对端处的入口(24)和出口(25)端口,用于使载满载货的空气流过 在所述端口(24,25)之间的所述腔室(45)和用于将清洁空气流入所述腔室(45)的旁路空气入口(46)。 旁路空气入口(46)构造成使得通过所述入口(46)进入腔室(45)的空气在腔室(45)中形成旋流器,其与在入口(24)和出口(24)之间流动的载药空气相互作用, 25)端口。 吸入器(1)可以具有锥形药物负载空气流动管道(70),以在进入腔室(45)和/或冲击元件(81,84,92,105)之间加速流动以使药物颗粒解聚。