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1. 发明申请

WO1996029943A1 PHOTODYNAMIC THERAPY SYSTEM AND METHOD 审中-公开
标题翻译：光动力治疗系统及方法
公开(公告)号：WO1996029943A1
公开(公告)日：1996-10-03
申请号：PCT/US1996004252
申请日：1996-03-27
申请人： ELI LILLY AND COMPANY
发明人： ELI LILLY AND COMPANY , AITA, Michael , BUCHIN, Michael
IPC分类号： A61B17/22
CPC分类号： A61N5/062 , A61B18/245 , A61B2017/22038 , A61B2017/22051 , A61B2017/22059 , A61B2017/22074 , A61B2017/22078 , A61B2017/22087 , A61N5/0601
摘要： A method and catheter system for irradiating a body lumen wall which comprises providing an elongated, flexible radiation transmission member having an emitting portion at its distal end, advancing the emitting portion to an area adjacent the wall defining the patient's body lumen to be treated by irradiation, and directing radiation through the transmission member while moving the transmission member to cause the emitting portion to irradiate a length of the wall of the body lumen. The transmission member may be rotated independently or in conjunction with longitudinal movement to achieve either selective or uniform irradiation of the wall defining the body lumen. In one embodiment, this invention comprises an elongated flexible shaft, having an inflatable member disposed at the distal end. A radiation transmission member having an emitting portion on its distal end is slidably disposed within the elongated shaft so that the emitting portion resides within the inflatable member. The system is configured so that the emitting portion may travel at least along the length of the inflatable member by longitudinally moving the transmission member. Optionally, the emitting portion may be configured to transmit radiation in a particular radial direction and the transmission member may be configured to rotate axially within the lumen.
摘要翻译：一种用于照射体腔壁的方法和导管系统，其包括提供细长的柔性辐射透射构件，其在其远端具有发射部分，将发射部分推进到邻近限定患者体腔的区域以通过照射进行治疗并且在移动所述透射构件的同时引导辐射通过所述透射构件，以使所述发射部分照射所述体腔的壁的一定长度。透射构件可以独立地或与纵向运动相结合地旋转，以实现限定体腔的壁的选择性或均匀照射。在一个实施例中，本发明包括细长的柔性轴，其具有设置在远端的可充气构件。在其远端具有发射部分的辐射传递构件可滑动地设置在细长轴内，使得发射部分位于可充气构件内。该系统构造成使得发射部分可以通过纵向移动传播构件至少沿着可充气构件的长度行进。可选地，发射部分可以被配置成在特定径向方向上透射辐射，并且透射构件可以构造成在腔内轴向旋转。

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