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1. 发明申请

WO2012024169A2 NON-INVASIVE TREATMENT OF BRONCHIAL CONSTRICTION 审中-公开
标题翻译：非正式协商的协商处理
公开(公告)号：WO2012024169A2
公开(公告)日：2012-02-23
申请号：PCT/US2011/047509
申请日：2011-08-12
申请人： ELECTROCORE LLC , SIMON, Bruce , ERRICO, Joseph , RAFFLE, John , MENDEZ, Steven
发明人： SIMON, Bruce , ERRICO, Joseph , RAFFLE, John , MENDEZ, Steven
IPC分类号： A61N2/04 , A61H1/00 , A61N7/00 , A61N5/06 , A61F7/00 , A61N1/36
CPC分类号： A61N2/002 , A61H23/00 , A61H23/004 , A61H23/02 , A61H23/0236 , A61H31/00 , A61H39/002 , A61H2201/123 , A61H2201/1604 , A61H2201/1609 , A61H2201/165 , A61N1/3601 , A61N1/36014 , A61N1/36114 , A61N1/3758 , A61N1/3787 , A61N1/40 , A61N2/006 , A61N2/02 , A61N5/0603 , A61N5/0622 , A61N5/0625 , A61N7/00 , A61N2005/0605 , A61N2005/063 , A61N2007/0026
摘要： Devices, systems and instructing methods are disclosed for treating bronchial constriction related to asthma, anaphylaxis or chronic obstructive pulmonary disease. The instructing method for treatment comprises transmitting impulses of energy non-invasively to selected nerve fibers that are responsible for smooth muscle dilation. The transmitted energy impulses, comprising magnetic and/or electrical, mechanical and/or acoustic, and optical and/or thermal energy, stimulate the selected nerve fibers.
摘要翻译：公开了用于治疗与哮喘，过敏反应或慢性阻塞性肺疾病相关的支气管收缩的装置，系统和指导方法。治疗的指导方法包括将能量非侵入性的脉冲传递给负责平滑肌肉扩张的选定的神经纤维。包括磁和/或电的机械和/或声学以及光学和/或热能的透射能量脉冲刺激所选择的神经纤维。

2. 发明申请

WO2011100006A1 SYSTEMS AND METHODS FOR TREATING OBESITY AND TYPE 2 DIABETES 审中-公开
标题翻译：用于治疗肥胖和2型糖尿病的系统和方法
公开(公告)号：WO2011100006A1
公开(公告)日：2011-08-18
申请号：PCT/US2010/055765
申请日：2010-11-08
申请人： ELECTROCORE LLC , PRIPLATA, Attila , ERRICO, Joseph , RAFFLE, John , GARDINER, Jonathan
发明人： PRIPLATA, Attila , ERRICO, Joseph , RAFFLE, John , GARDINER, Jonathan
IPC分类号： A61M29/00
CPC分类号： A61F5/0076 , A61B17/3468 , A61B2017/00557 , A61B2017/00818 , A61F5/004 , A61F5/0079 , A61F2002/045 , A61M25/04 , A61M27/002 , A61M39/00 , A61M39/10
摘要： The present invention provides systems and methods for treating and controlling obesity and/or type II diabetes. In one aspect of the invention, a bypass device includes gastric and duodenal anchors coupled to each other and positioned on either side of the pylorus and a hollow sleeve designed to extend from the pylorus through at least a proximal portion of a patient's small intestine. The gastric and duodenal anchors are movable between collapsed configurations for advancement through the esophagus and an expanded configuration for inhibiting movement of the anchors through the pyloric sphincter. Thus, the bypass device can be placed and removed endoscopically through the patient's esophagus in a minimally invasive outpatient procedure and it is "self-anchoring" and does not require invasive tissue fixation within the patient's GI tract, thereby reducing collateral tissue damage and minimizing its impact on the digestive process.
摘要翻译：本发明提供用于治疗和控制肥胖症和/或II型糖尿病的系统和方法。在本发明的一个方面，旁路装置包括彼此联接并定位在幽门的任一侧上的胃和十二指肠锚，以及设计成从幽门延伸穿过患者小肠的至少近端部分的中空套管。胃和十二指肠锚固件可以在通过食道前进的收缩构型之间移动，以及用于阻止锚通过幽门括约肌运动的扩张构型。因此，旁路装置可以以微创门诊手术方式通过患者的食管内窥镜放置和移除，并且它是“自我锚定”的，并且不需要在患者胃肠道内进行侵入性组织固定，从而减少旁侧组织损伤并使其最小化对消化过程的影响。

3. 发明申请

WO2011062882A1 SYSTEMS AND METHODS FOR TREATMENT OF OBESITY AND TYPE 2 DIABETES 审中-公开
标题翻译：用于治疗肥胖和2型糖尿病的系统和方法
公开(公告)号：WO2011062882A1
公开(公告)日：2011-05-26
申请号：PCT/US2010/056789
申请日：2010-11-16
申请人： E2 LLC , PRIPLATA, Attila , ERRICO, Joseph , RAFFLE, John , GARDINER, Jonathan
发明人： PRIPLATA, Attila , ERRICO, Joseph , RAFFLE, John , GARDINER, Jonathan
IPC分类号： A61F2/04
CPC分类号： A61M27/002 , A61F2/04 , A61F5/0076 , A61F2002/044
摘要： The present invention provides systems and methods for treating and controlling obesity and/or type II diabetes. In one aspect of the invention, a device comprises a hollow sleeve sized and shaped for positioning within a duodenum of the patient, an anchor coupled to the proximal end of the sleeve and being sized and shaped to inhibit distal migration of the sleeve and a plurality of elastomeric objects coupled to the distal end of the sleeve and being sized and shaped to inhibit proximal migration of the sleeve through a pylorus of the patient. The bypass device can be placed and removed endoscopically through the patient's esophagus in a minimally invasive outpatient procedure and it is "self-anchoring" and does not require invasive tissue fixation within the patient's GI tract, thereby reducing collateral tissue damage and minimizing its impact on the digestive process.
摘要翻译：本发明提供用于治疗和控制肥胖症和/或II型糖尿病的系统和方法。在本发明的一个方面，一种装置包括尺寸和形状适于定位在患者的十二指肠内的中空套筒，联接到套筒的近端的锚固件，其尺寸和形状被设计成阻止套筒的远端移动，并且多个耦合到套筒的远端的弹性体物体的尺寸和形状以阻止套管穿过患者幽门的近端迁移。旁路装置可以通过患者的食管在微创门诊手术中内窥镜放置和移除，并且它是“自我锚定”的，并且不需要在患者胃肠道内进行侵入性组织固定，从而减少侧支组织损伤并使其对消化过程。

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