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1. 发明申请

WO2021191331A1 MULTI-MODAL RETINAL IMAGING PLATFORM 审中-公开
公开(公告)号：WO2021191331A1
公开(公告)日：2021-09-30
申请号：PCT/EP2021/057680
申请日：2021-03-25
申请人： ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
发明人： KÜNZI, Matthieu , LAFOREST, Timothé , MOSER, Christophe
IPC分类号： A61B3/00 , A61B3/10 , A61B3/12 , A61B3/18 , A61B3/0008 , A61B3/1015 , A61B3/102 , A61B3/1225 , A61B3/1241
摘要： The invention relates to oblique transscleral illumination of an eye fundus with at least one physical point light source around the eye allowing for dark field imaging combined with optical coherence tomography imaging.

2. 发明申请

WO2017195163A1 SYSTEM, METHOD AND APPARATUS FOR RETINAL ABSORPTION PHASE AND DARK FIELD IMAGING WITH OBLIQUE ILLUMINATION 审中-公开
标题翻译：用于具有斜视照明的视网膜吸收和暗场成像的系统，方法和设备
公开(公告)号：WO2017195163A1
公开(公告)日：2017-11-16
申请号：PCT/IB2017/052803
申请日：2017-05-12
申请人： ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
发明人： LAFOREST, Timothé , CARPENTRAS, Dino , MOSER, Christophe , KÜNZI, Mathieu
IPC分类号： A61B3/00 , A61B3/10 , A61B3/12
摘要： A method for imaging a tissue of an eye, the method including the steps of providing oblique illumination to the eye by a plurality of light emitting areas of a light delivery device, the plurality of light emitting areas being independently controllable and arranged to direct light towards at least one of a retina and an iris of the eye, causing an output beam from light backscattered from the at least one of the retina and the iris by the oblique illumination, capturing the output beam with an imaging system to provide a sequence of images of a fundus of the eye, and retrieving a phase and absorption contrast image from the sequence of images of the fundus, wherein the sequence of images of the fundus of the step of capturing is obtained by sequentially turning on one or more of the plurality of light emitting areas at a time in the step of providing the oblique illumination.
摘要翻译：一种用于对眼睛组织成像的方法，所述方法包括以下步骤：通过光递送装置的多个发光区域向眼睛提供倾斜照明，所述多个发光区域是可独立控制并布置成将光导向眼睛的视网膜和虹膜中的至少一个，使得来自光的输出光束通过倾斜照明从视网膜和虹膜中的至少一个后向散射，从而捕获输出光束成像系统以提供眼睛的眼底的图像序列，并且从眼底的图像序列中检索相位和吸收对比图像，其中捕获步骤的眼底的图像序列是通过顺序地转动在提供倾斜照明的步骤中一次在多个发光区域中的一个或多个发光区域上

3. 发明申请

WO2021058367A1 SYSTEM AND METHODS FOR DIFFERENTIAL IMAGING USING A LOCK-IN CAMERA 审中-公开
公开(公告)号：WO2021058367A1
公开(公告)日：2021-04-01
申请号：PCT/EP2020/075968
申请日：2020-09-17
申请人： ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
发明人： LOTERIE, Damien , BONATI, Chiara , LAFOREST, Timothé , MOSER, Christophe
IPC分类号： G02B21/00 , G01S17/894 , G02B21/14 , G02B21/36
摘要： The present invention describes an imaging system that allows visualization of a wide range of samples both in terms of morphology and in terms of material (e.g. density distribution, varying chemical composition, or anything that induces a change of optical path). The application of this imaging system includes absorptive samples as well as nearly and fully transparent samples with respect to the wavelength of illumination. Two elements are key in this system: the use of a so-called lock-in camera, and the synchronization of the recording to a modulation of choice along the image forming apparatus. Such modulation can consist for example in modulation of the illumination, use of filters, tilt/rotation of the sample or of certain microscope components.

4. 发明申请

WO2020121243A1 OPHTHALMIC SYSTEM AND METHOD FOR CLINICAL DEVICE USING TRANSCLERAL ILLUMINATION WITH MULTIPLE POINTS SOURCE 审中-公开
公开(公告)号：WO2020121243A1
公开(公告)日：2020-06-18
申请号：PCT/IB2019/060707
申请日：2019-12-12
申请人： ECOLE POLYTECHNIQUE FEDERALE DE LAUSANNE (EPFL)
发明人： LAFOREST, Timothé , MOSER, Christophe , KUNZI, Mathieu
IPC分类号： A61B3/00 , A61B3/12
摘要： An ophthalmic illumination and imaging system with transscleral / transpalpebral illumination of the eye fundus comprises a light-delivering device with a plurality of emitting areas; each of the emitting areas being configured to be independently controllable and directed towards the sclera of the intended eye to measure, providing transscleral oblique illumination of the eye fundus; an active eye aberration correcting system; and an imaging system configured to create multiple images of the eye fundus on multiple imaging sensors.

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