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1. 发明申请

WO2010072584A1 BILE ACIDS IN FEED FOR REDUCING METHANE PRODUCTION EMANATING FROM THE DIGESTIVE ACTIVITIES OF RUMINANTS 审中-公开
标题翻译：饲料中的不同种类，用于减少发酵生物活性的甲烷生产
公开(公告)号：WO2010072584A1
公开(公告)日：2010-07-01
申请号：PCT/EP2009/066893
申请日：2009-12-11
申请人： DSM IP ASSETS B.V. , DUVAL, Stephane , IMMIG, Irmgard , DE SAIZIEU, Antoine
发明人： DUVAL, Stephane , IMMIG, Irmgard , DE SAIZIEU, Antoine
IPC分类号： A23K1/16 , A23K1/18
CPC分类号： A23K50/10 , A23K20/105 , A23V2002/00 , Y02P60/56 , A23V2250/30
摘要： The present invention relates to a method for reducing the production of methane emanating from the digestive activities of a ruminant by using, as active compound deoxycholic acid and/or chenodeoxycholic acid and/or a derivative thereof, which is administrated to the animal. The invention also relates to the use of these ingredients in feed and feed additives such as premix, concentrates and total mixed ration (TMR) or in the form of a bolus.
摘要翻译：本发明涉及通过使用向动物施用的作为活性化合物脱氧胆酸和/或鹅脱氧胆酸和/或其衍生物来减少由反刍动物的消化活性产生的甲烷的产生方法。本发明还涉及这些成分在饲料和饲料添加剂如预混物，浓缩物和总混合比例（TMR）中或在丸剂形式中的用途。

2. 发明申请

WO2012160191A2 USE OF A FEED COMPOSITION FOR REDUCING METHANE EMISSION IN RUMINANTS, AND/OR TO IMPROVE RUMINANT PERFORMANCE 审中-公开
标题翻译：使用饲料组合物降低发酵液中的甲烷排放和/或提高发酵剂性能
公开(公告)号：WO2012160191A2
公开(公告)日：2012-11-29
申请号：PCT/EP2012/059826
申请日：2012-05-25
申请人： DSM IP ASSETS B.V. , DUVAL, Stephane , IMMIG, Irmgard , KINDERMANN, Maik , WEBER, Gilbert
发明人： DUVAL, Stephane , IMMIG, Irmgard , KINDERMANN, Maik , WEBER, Gilbert
IPC分类号： A23K1/16 , A23K1/17 , A23K1/18
CPC分类号： A61K31/21 , A23K20/10 , A23K20/105 , A23K20/195 , A23K50/10 , A61K9/0053 , A61K31/04 , A61K31/215 , A61K31/22 , A61K31/221 , A61K31/23 , A61K31/235 , A61K31/24 , A61K31/255 , A61K31/275 , A61K31/34 , A61K31/35 , A61K31/351 , A61K31/44 , A61K31/4406 , A61K45/06 , Y02P60/56
摘要： The present invention relates to the field of reduction of methane emission in ruminants. Particularly, it relates to the use of a feed composition or a feed additive comprising at least one antibiotic and at least one organic molecule substituted at any position with at least one nitrooxy group for reducing the production of methane emanating from the digestive activities of ruminants, and/or to improve the ruminant performance.
摘要翻译：本发明涉及反刍动物甲烷排放减少的领域。特别地，本发明涉及使用包含至少一种抗生素和至少一种在任何位置与至少一个硝基氧基取代的有机分子的饲料组合物或饲料添加剂，用于减少由反刍动物的消化活性产生的甲烷的产生，和/或提高反刍动物的表现。

3. 发明申请

WO2004082398A1 FAT SOLUBLE VITAMIN FEED SUPPLEMENTS AND PROCESSES FOR DELIVERING SAME 审中-公开
标题翻译：脂肪可溶性维生素饲料补充剂和交付方法
公开(公告)号：WO2004082398A1
公开(公告)日：2004-09-30
申请号：PCT/EP2004/002514
申请日：2004-03-11
申请人： DSM IP ASSETS B.V. , WILSON, Jonathan, W. , IMMIG, Irmgard , WILKIE, Ross
发明人： WILSON, Jonathan, W. , IMMIG, Irmgard , WILKIE, Ross
IPC分类号： A23K1/18
CPC分类号： A23K50/42 , A23K20/158 , A23K20/174 , A23K40/00 , A23K50/10 , A23K50/70
摘要： A process is disclosed for delivering a stable, fat soluble vitamin to a feed composition. The process includes dissolving a fat soluble vitamin in a solvent to form a vitamin-enriched solvent and combining the vitamin-enriched feeds; processes for supplementing the diet of a feed animal with a fat soluble vitamin, processes for extending the shelf life of an animal product, and processes for making stable vitamin-enriched supplements for feed compositions are also provided.
摘要翻译：公开了一种将稳定的脂溶性维生素递送至饲料组合物的方法。该方法包括将脂溶性维生素溶解在溶剂中以形成富含维生素的溶剂并将富含维生素的饲料混合; 还提供了用脂肪可溶性维生素补充饲料动物饮食的过程，用于延长动物产品的保质期的方法，以及用于制备用于饲料组合物的稳定的富含维生素的补充剂的方法。

4. 发明申请

WO2008006881A1 USE OF BACTERIAL AMYLASES IN FEED FOR BOVINE ANIMALS 审中-公开
标题翻译：在牛肉饲料饲料中使用细菌淀粉
公开(公告)号：WO2008006881A1
公开(公告)日：2008-01-17
申请号：PCT/EP2007/057189
申请日：2007-07-12
申请人： DSM IP ASSETS B.V. , NOVOZYMES A/S , STEINBERG, Wolfgang , IMMIG, Irmgard , GLITSOE, Vibe , FISCHER, Morten
发明人： STEINBERG, Wolfgang , IMMIG, Irmgard , GLITSOE, Vibe , FISCHER, Morten
IPC分类号： A23K1/18 , A23K1/14 , A23K1/165
CPC分类号： A23K50/10 , A23K10/14 , A23K10/37 , Y02P60/877
摘要： The invention relates to the use of at least one bacterial amylase in feed for ruminant animals of the subfamily Bovinae in particular for improving milk yield, apparent digestibility of the diet fed, feedstuff dry matter disappearance, weight gain, and/or Feed Conversion Ratio (FCR). Examples of bovine animals are dairy cows and beef cattle. The invention also relates to the use of such amylases in feed and feed additives such as premix, concentrates and total mixed ration (TMR). The amylase may be used in combination with cellulase for improving milk yield and/or back fat thickness. Preferred amylases are derived from Bacillus halmapalus, licheniformis, and stearothermophilus and are preferably homologous to Bacillus stearothermophilus amylase.
摘要翻译：本发明涉及至少一种细菌淀粉酶在Bovina亚科的反刍动物的饲料中的用途，特别是用于改善牛奶产量，饲料的表观消化率，饲料干物质消失，体重增加和/或饲料转化率 FCR）。牛类动物的例子是奶牛和肉牛。本发明还涉及这样的淀粉酶在饲料和饲料添加剂如预混物，浓缩物和总混合比例（TMR）中的用途。淀粉酶可以与纤维素酶组合使用以改善产奶量和/或背部脂肪厚度。优选的淀粉酶衍生自Bacillus halmapalus，地衣芽孢杆菌和嗜热脂肪芽孢杆菌，并且优选与嗜热脂肪芽孢杆菌淀粉酶同源。

5. 发明申请

WO2005048709A1 USE OF PANTHENOL IN TEAT DIP/SPRAY PREPARATIONS 审中-公开
标题翻译： PANENENOL在TEAT DIP / SPRAY制剂中的应用
公开(公告)号：WO2005048709A1
公开(公告)日：2005-06-02
申请号：PCT/EP2004/012024
申请日：2004-10-25
申请人： DSM IP ASSETS B.V. , ELLIOTT, Robert , IMMIG, Irmgard
发明人： ELLIOTT, Robert , IMMIG, Irmgard
IPC分类号： A01N37/36
CPC分类号： A61K45/06 , A01N37/36 , A61K9/0041 , A61K9/7015 , A61K31/164 , A61K33/18 , A01N59/12 , A01N59/00 , A01N25/30 , A01N2300/00 , A61K2300/00
摘要： Aqueous antimicrobial compositions useful in the treatment of animal teats, characterized by an effective amount of panthenol, normally 0.1-8% (w/w), and the use of panthenol for the preparation of such compositions.
摘要翻译：用于治疗动物乳头的水性抗微生物组合物，其特征在于有效量的泛醇，通常为0.1-8％（w / w），以及使用泛醇制备这种组合物。

6. 发明申请

WO2015086755A1 NOVEL USE OF BIOTIN AND NATURAL ESSENTIAL OILS FOR BOVINE ANIMALS FOR THE PREVENTION AND TREATMENT OF KETOSIS 审中-公开
标题翻译：生物医药和自然基础油用于预防和治疗卡特西斯的牛血清动物的新用途
公开(公告)号：WO2015086755A1
公开(公告)日：2015-06-18
申请号：PCT/EP2014/077399
申请日：2014-12-11
申请人： DSM IP ASSETS B.V.
发明人： IMMIG, Irmgard , STEINBERG, Wolfgang , MC GRATH, Joseph
IPC分类号： A61K31/4188 , A61K31/11 , A61K31/05 , A23K1/00 , A61P43/00 , A61P3/00
CPC分类号： A61K31/4188 , A23K20/10 , A23K20/158 , A23K20/174 , A23K50/10 , A61K31/05 , A61K31/085 , A61K31/11 , A61K2300/00
摘要： The present invention is made for the prevention of ketosis or minimizing the effects of ketosis in ruminant animals. This purpose is achieved by feeding to the animal biotin in combination with a mixture of at least two essential oil compounds selected from the group consisting of thymol, eugenol, meta-cresol, vaniline and guajacol. The present invention is useful because it is capable of preventing and/or inhibiting ketosis of calving ruminant animals and the subsequent need for veterinary treatment. In a preferred embodiment of a feeding concept for dairy cattle, especially calving dairy cattle, biotin being used in an amount sufficient to provide a daily dosage of 10 mg to 20 mg per head to which it is to be administered. It is at present contemplated that the essential oils are administered in amounts (total dosage ranges of essential oils) of 1 to 1.5 g per head per day.
摘要翻译：本发明是为了预防酮症或使反刍动物中酮症的作用最小化。该目的通过与至少两种选自百里香酚，丁子香酚，间甲酚，香草胺和瓜那醇的精油化合物的混合物联合给动物生物素来实现。本发明是有用的，因为它能够预防和/或抑制产犊反刍动物的酮症和随后的兽医治疗需要。在用于奶牛，特别是犊牛奶牛的喂养概念的优选实施方案中，生物素的用量足以提供每日10mg剂量至每头给予10mg。目前预期精油以每天头数为1至1.5g的量（精油的总剂量范围）施用。

7. 发明申请

WO2017137489A1 ANTI-METHANOGENIC COMPOSITIONS AND USES THEREOF 审中-公开
标题翻译：抗甲醇成分及其用途
公开(公告)号：WO2017137489A1
公开(公告)日：2017-08-17
申请号：PCT/EP2017/052851
申请日：2017-02-09
申请人： DSM IP ASSETS B.V.
发明人： DUVAL, Stephane , IMMIG, Irmgard , KINDERMANN, Maik
IPC分类号： A61K31/21 , A61K31/216 , A61K31/22 , A61K31/235 , A61K31/275 , A61K31/34 , A61K31/4406 , A61K9/28 , A61P1/00 , A61P1/10 , A61P3/04
CPC分类号： A61K31/21 , A61K9/2846 , A61K31/216 , A61K31/22 , A61K31/235 , A61K31/275 , A61K31/34 , A61K31/4406
摘要： The present invention relates to a method for reducing the symptoms of constipation, irritable bowel syndrome, discomfort from gaseous distention, and/ or obesity in humans. More particularly, it relates to the use of a nitrooxy organic molecule to reduce the symptoms, and/or treat constipation, irritable bowel syndrome, discomfort from gaseous distention, and obesity.
摘要翻译：本发明涉及用于减轻便秘，肠易激综合征，气体膨胀引起的不适，和/或人体肥胖的症状的方法。更具体地说，涉及使用硝基氧基有机分子来减轻症状，和/或治疗便秘，肠易激综合症，气体膨胀引起的不适以及肥胖症。

8. 发明申请

WO2015086758A1 NOVEL USE OF BIOTIN AND NATURAL ESSENTIAL OILS FOR BOVINE ANIMALS TO IMPROVE BEEF QUALITY 审中-公开
标题翻译：生物饮食和自然基础油用于牛血清动物提高贝类质量的新用途
公开(公告)号：WO2015086758A1
公开(公告)日：2015-06-18
申请号：PCT/EP2014/077404
申请日：2014-12-11
申请人： DSM IP ASSETS B.V.
发明人： IMMIG, Irmgard , STEINBERG, Wolfgang , MC GRATH, Joseph
IPC分类号： A23K1/16 , A23K1/18
CPC分类号： A61K31/4188 , A23K20/10 , A23K20/105 , A23K20/111 , A23K20/158 , A23K20/174 , A23K50/10 , A61K9/0056 , A61K31/05 , A61K31/085 , A61K31/11
摘要： The present invention is made for the purpose of improving beef quality and upgrading its fat marbling standard (which is called beef marbling standard, or BMS). The fat marbling state is generally called "Shimofuri" in Japanese. This purpose is achieved by feeding to the animal biotin in combination with a mixture of at least two essential oil compounds selected from the group consisting of thymol, eugenol, meta-cresol, vaniline and guajacol. In a preferred embodiment of the invention, biotin is used in an amount sufficient to provide a daily dosage of 0.01 mg to 0.3 mg per kg body weight and the essential oils are administered in amounts (total dosage ranges of essential oils) of 0.5 to 4 mg per kg body weight per day. In terms of the quality of the meat, the combined use of biotin and the essential oils as defined above shows significant differences in the fat marbling (Shimofuri), luster, firmness and texture of the meat compared to the meat of non-treated animals.
摘要翻译：本发明是为了提高牛肉质量和提高其大理石肥料标准（称为牛排大理石标准或BMS）。胖的大理石花纹状态通常被称为日本的“Shimofuri”。该目的通过与至少两种选自百里酚，丁子香酚，间甲酚，香草胺和瓜那醇的至少两种精油化合物的混合物联合给动物生物素来实现。在本发明的一个优选实施方案中，生物素的用量足以提供0.01mg至0.3mg / kg体重的日剂量，并且精油以0.5至4的量（精油的总剂量范围） mg / kg体重每天。在肉的质量方面，如上所述，生物素和精油的组合使用显示与未经处理的动物相比，肉的脂肪大理石（Shimofuri），光泽，坚实度和质地差异显着。

9. 发明申请

WO2016128530A1 A METHOD FOR IMPROVING FEED DIGESTIBILITY IN BOVINE ANIMALS 审中-公开
标题翻译：一种提高牛血清饲料可食性的方法
公开(公告)号：WO2016128530A1
公开(公告)日：2016-08-18
申请号：PCT/EP2016/052957
申请日：2016-02-12
申请人： DSM IP ASSETS B.V.
发明人： ACEDO, Tiago , IMMIG, Irmgard , TAMASSIA, Luis
IPC分类号： A23K20/111 , A23K20/189 , A23K20/195 , A23K50/10 , A61K31/045 , A61K31/11
CPC分类号： A61K38/47 , A23K20/111 , A23K20/189 , A23K20/195 , A23K50/10 , A61K31/045 , A61K31/05 , A61K31/11 , C12Y302/01001
摘要： The invention relates to the use of at least one bacterial amylase in combination with a mixture of at least two essential oil compounds selected from the group consisting of thymol, eugenol, meta-cresol, vaniline and guajacol in feed for ruminant animals of the subfamily Bovinae for improving weight gain, milk yield and/or Feed Conversion Ratio (FCR). Examples of bovine animals are beef cattle and dairy cows.
摘要翻译：本发明涉及至少一种细菌淀粉酶与选自下组的至少两种精油化合物的混合物在Bovinae亚科的反刍动物的饲料中的应用，所述精油化合物选自百里酚，丁子香酚，间甲酚，香草胺和瓜那醇用于改善体重增加，产奶量和/或饲料转化率（FCR）。牛类动物的例子是肉牛和奶牛。

10. 发明申请

WO2015091208A1 USE OF 25-HYDROXY VITAMIN D3 TO PROMOTE CALCIUM ABSORPTION IN RUMINANTS 审中-公开
标题翻译：使用25-羟基维生素D3促进血浆中的钙吸收
公开(公告)号：WO2015091208A1
公开(公告)日：2015-06-25
申请号：PCT/EP2014/077405
申请日：2014-12-11
申请人： DSM IP ASSETS B.V.
发明人： IMMIG, Irmgard
IPC分类号： A23K1/16 , A23K1/18
CPC分类号： A23K50/10 , A23K20/174
摘要： It has been found that administering 25-hydroxy vitamin D3 to ruminants helps to reduce the need for supplemental inorganic Ca in the diets while maintaining milk production or growth performance.. Thus the aspect of this invention is a method of promoting Calcium absorption in ruminants, comprising administering a sufficient amount of 25-hydroxy vitamin D3 to the animal.
摘要翻译：已经发现，向反刍动物施用25-羟基维生素D3有助于减少对饮食中补充的无机Ca的需要，同时保持产奶量或生长性能。因此，本发明的方面是促进反刍动物中钙吸收的方法，包括向动物施用足量的25-羟基维生素D3。

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