专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

1. 发明申请

WO03059381A2 IMMUNOGENIC PREPARATIONS AND VACCINES ON THE BASIS OF RNA 审中-公开
标题翻译：基于RNA的免疫制备和疫苗
公开(公告)号：WO03059381A2
公开(公告)日：2003-07-24
申请号：PCT/EP0300497
申请日：2003-01-20
申请人： CUREVAC GMBH , PASTEUR INSTITUT , INST NAT SANTE RECH MED , GENETHON III , PASCOLO STEVE CYRIL , HOERR INGMAR , RAMMENSEE HANS-GEORG , VON DER MUELBE FLORIAN , MICHEL MARIE-LOUISE , FIRAT HUESEYIN , LEMONNIER FRANCOIS ALBERT
发明人： PASCOLO STEVE CYRIL , HOERR INGMAR , RAMMENSEE HANS-GEORG , VON DER MUELBE FLORIAN , MICHEL MARIE-LOUISE , FIRAT HUESEYIN , LEMONNIER FRANCOIS ALBERT
IPC分类号： A61K39/21 , A61K39/29 , A61K48/00 , A61P31/00 , A61P31/18 , A61P31/20 , C07K14/02 , C07K14/16 , A61K39/00
CPC分类号： C07K14/005 , A61K39/12 , A61K39/21 , A61K39/29 , A61K39/292 , A61K48/00 , A61K2039/53 , A61K2039/55516 , A61K2039/55522 , C12N2730/10122 , C12N2730/10134 , C12N2740/16022 , C12N2740/16034 , C12N2770/24222 , C12N2770/24234
摘要： The present invention relates to the field of vaccination and immune stimulation by the use of nucleic acids, in particular RNA, coding for one or more antigens of pathogenic micro organisms.
摘要翻译：本发明涉及通过使用编码一种或多种病原微生物抗原的核酸，特别是RNA来进行疫苗接种和免疫刺激的领域。

2. 发明申请

WO2011073215A3 HLA-BINDING PEPTIDES DERIVED FROM PROSTATE-ASSOCIATED ANTIGENIC MOLECULES AND METHODS OF USE THEREOF 审中-公开
标题翻译：前列腺相关抗原分子衍生的HLA-结合肽及其使用方法
公开(公告)号：WO2011073215A3
公开(公告)日：2011-10-06
申请号：PCT/EP2010069675
申请日：2010-12-14
申请人： IMMATICS BIOTECHNOLOGIES GMBH , RAMMENSEE HANS-GEORG , STEVANOVIC STEFAN , GOUTTEFANGEAS CECILE , WEINSCHENK TONI , LEWANDROWSKI PETER
发明人： RAMMENSEE HANS-GEORG , STEVANOVIC STEFAN , GOUTTEFANGEAS CECILE , WEINSCHENK TONI , LEWANDROWSKI PETER
IPC分类号： A61K39/00 , C07K14/47 , C07K14/705
CPC分类号： C07K14/4748 , A61K39/0011 , A61K2039/55566
摘要： Methods and compositions for immunotherapeutic treatment of prostate cancer are disclosed. Patients are treated with compositions comprising HLA-binding peptides derived from prostate-associated antigenic molecules, either with or without immunological adjuvants.
摘要翻译：公开了用于免疫治疗前列腺癌的方法和组合物。用含或不含免疫佐剂的包含源自前列腺相关抗原性分子的HLA结合肽的组合物治疗患者。

3. 发明申请

WO2012079878A3 HLA-BINDING PEPTIDES DERIVED FROM PROSTATE-ASSOCIATED ANTIGENIC MOLECULES AND METHODS OF USE THEREOF 审中-公开
标题翻译：前列腺相关抗原分子衍生的HLA-结合肽及其使用方法
公开(公告)号：WO2012079878A3
公开(公告)日：2012-08-09
申请号：PCT/EP2011070024
申请日：2011-11-14
申请人： IMMATICS BIOTECHNOLOGIES GMBH , WEINSCHENK TONI , LEWANDROWSKI PETER , RAMMENSEE HANS-GEORG , STEVANOVIC STEFAN , GOUTTEFANGEAS CECILE
发明人： WEINSCHENK TONI , LEWANDROWSKI PETER , RAMMENSEE HANS-GEORG , STEVANOVIC STEFAN , GOUTTEFANGEAS CECILE
IPC分类号： A61K39/00 , C07K14/47 , C07K14/705
CPC分类号： A61K39/0011 , A61K2039/55566 , C07K14/4748
摘要： Methods and compositions for immunotherapeutic treatment of prostate cancer are disclosed. More specifically methods of treating patients with prostate cancer comprising administering compositions comprising HLA-binding peptides derived from prostate-associated antigenic molecules, either with or without immunological adjuvants, are disclosed.
摘要翻译：公开了用于免疫治疗前列腺癌的方法和组合物。更具体地说，公开了治疗患有前列腺癌的患者的方法，包括给予包含来源于前列腺相关抗原性分子的HLA结合肽的组合物，所述组合物含有或不含免疫佐剂。

4. 发明申请

WO2005076009A3 METHOD FOR IDENTIFYING AND QUANTIFYING OF TUMOUR-ASSOCIATED PEPTIDES 审中-公开
标题翻译：肿瘤相关肽鉴定和定量方法
公开(公告)号：WO2005076009A3
公开(公告)日：2006-07-27
申请号：PCT/EP2005000873
申请日：2005-01-28
申请人： IMMATICS BIOTECHNOLOGIES GMBH , LEMMEL CLAUDIA , RAMMENSEE HANS-GEORG
发明人： LEMMEL CLAUDIA , RAMMENSEE HANS-GEORG
IPC分类号： G01N33/68 , C07K7/06 , G01N33/574
CPC分类号： G01N33/6878 , C07K7/06 , G01N33/57484 , G01N33/6842 , G01N33/6848 , G01N2333/70539 , Y10T436/24
摘要： Described is a method for identifying and quantifying of tumour-associated peptides, wherein first at least two different sources for obtaining the peptide are provided (tumourous and healthy tissue), and, separately of one another, the peptides from the different sources are chemically modified in an identical manner by using at least two different stable isotopes of the same element. Subsequently, the peptides are isolated by a chromatographic method, and the amino acid sequences of the peptides are determined, wherein the determination of the relative amount ratios of peptides having the identical sequence from different samples one to the other occurs by using a stable isotope in the chemical modification. Furthermore, the invention relates to a tumour-associated peptide having an amino acid sequence that is selected from the group consisting of SEQ-ID No. 1 to 36 from the accompanying sequence protocol, wherein the peptide has the ability to bind to a molecule of the human major histocompatibility complex (MHC) class-I. Furthermore, the invention relates to the use of the peptides for producing a medicament and for the treatment of tumourous diseases and/or adenomatous diseases. Furthermore, a pharmaceutical composition is described that comprises at least one of the peptides.
摘要翻译：描述了用于鉴定和定量肿瘤相关肽的方法，其中提供了用于获得肽的第一至少两种不同来源（肿瘤和健康组织），并且彼此分开地来自不同来源的肽被化学修饰通过使用相同元素的至少两种不同的稳定同位素以相同的方式。随后，通过色谱法分离肽，并测定肽的氨基酸序列，其中通过使用稳定同位素来测定具有来自不同样品的相同序列的肽的相对量比例化学改性。此外，本发明涉及具有选自SEQ ID NO：1至36的氨基酸序列的肿瘤相关肽，所述氨基酸序列来自所述序列方案，其中所述肽具有与人类主要组织相容性复合体（MHC）I类。此外，本发明涉及肽用于制备药物和治疗肿瘤疾病和/或腺瘤性疾病的用途。此外，描述了包含至少一种肽的药物组合物。

5. 发明申请

WO2006037421A3 IMMUNOGENIC T-HELPER EPITOPES FROM HUMAN TUMOUR ANTIGENS AND IMMUNOTHERAPEUTIC METHODS USING SAID EPITOPES 审中-公开
标题翻译：免疫原性T-HELPER来自人肿瘤抗原的免疫组织化学和免疫治疗方法
公开(公告)号：WO2006037421A3
公开(公告)日：2006-06-29
申请号：PCT/EP2005009719
申请日：2005-09-09
申请人： IMMATICS BIOTECHNOLOGIES GMBH , RAMMENSEE HANS-GEORG , WEINSCHENK TONI , DENGJEL JOERN
发明人： RAMMENSEE HANS-GEORG , WEINSCHENK TONI , DENGJEL JOERN
IPC分类号： C07K14/47 , A61K39/00 , C12N15/00 , C12N15/62 , G01N33/574
CPC分类号： C07K14/4748
摘要： The present invention relates to immunotherapeutic methods, and molecules and cells for use in immunotherapeutic methods. In particular, the present invention relates to the immunotherapy of cancer, in particular renal cancer. The present invention furthermore relates to tumour-associated T-helper cell peptide epitopes, alone or in combination with other tumour-associated peptides, that serve as active pharmaceutical ingredients of vaccine compositions which stimulate anti-tumour immune responses. In particular, the present invention relates to 338 novel peptide sequences derived from HLA class II molecules of human tumour cell lines which can be used in vaccine compositions for eliciting anti-tumour immune responses.
摘要翻译：本发明涉及免疫治疗方法，以及用于免疫治疗方法的分子和细胞。特别地，本发明涉及癌症，特别是肾癌的免疫治疗。本发明还涉及用作刺激抗肿瘤免疫应答的疫苗组合物的活性药物成分的单独或与其它肿瘤相关肽组合的肿瘤相关T辅助细胞肽表位。特别地，本发明涉及可用于引发抗肿瘤免疫应答的疫苗组合物中的338种来自人类肿瘤细胞系HLA II类分子的新型肽序列。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式