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1. 发明申请

WO2013055568A1 ENGAGED FIDUCIALS AND SYSTEM FOR DEPLOYMENT 审中-公开
标题翻译：联合制作和部署制度
公开(公告)号：WO2013055568A1
公开(公告)日：2013-04-18
申请号：PCT/US2012/058679
申请日：2012-10-04
申请人： COOK MEDICAL TECHNOLOGIES LLC , MURRAY, Mark , CAMPBELL, Triona , MCHUGO, Vincent , CLANCY, Michael , NEILAN, John
发明人： MURRAY, Mark , CAMPBELL, Triona , MCHUGO, Vincent , CLANCY, Michael , NEILAN, John
IPC分类号： A61B19/00
CPC分类号： A61B19/54 , A61B17/3468 , A61B90/39 , A61B2017/00477 , A61B2090/3925 , A61B2090/3966 , A61B2090/3987 , A61B2090/3991 , A61N5/1001 , A61N5/1027 , A61N5/1049
摘要： Embodiments include a fiducial deployment system including a needle and at least two adjacent and releasably-engaged fiducials retained within a lumen of the needle by engagement with each other and/or by engagement with a pusher element. A fiducial may include one or more mechanical engagement structures that interengage with and/or are rupturably attached to one or more adjacent fiducials. The needle, which may include echogenic enhancements, may be configured to deliver a plurality of fiducials to a target location in serial fashion, one at a time. A variety of releasably-engaged fiducials are disclosed, as are methods for use.
摘要翻译：实施例包括基准展开系统，其包括针和通过彼此接合和/或通过与推动器元件接合而保持在针的内腔内的至少两个相邻且可释放地接合的基准。基准可以包括与一个或多个相邻基准相互联系和/或可破裂地附接到一个或多个相邻基准的一个或多个机械接合结构。可以包括回声增强的针可以被配置为以串联的方式一个一个地将多个基准传送到目标位置。公开了各种可释放地接合的基准，以及使用的方法。

2. 发明申请

WO2013003119A1 SYSTEM FOR FIDUCIAL DEPLOYMENT 审中-公开
标题翻译： FIDUCI部署系统
公开(公告)号：WO2013003119A1
公开(公告)日：2013-01-03
申请号：PCT/US2012/043146
申请日：2012-06-19
申请人： COOK MEDICAL TECHNOLOGIES LLC , MCHUGO, Vincent , CLANCY, Michael , NEILAN, John
发明人： MCHUGO, Vincent , CLANCY, Michael , NEILAN, John
IPC分类号： A61B17/34
CPC分类号： A61B17/3468 , A61B90/39 , A61B2090/3925 , A61B2090/3966 , A61B2090/3987
摘要： Embodiments include a fiducial deployment system including a needle and at least one splayed-end fiducial retained within the needle by frictional engagement and/or by engagement of the splayed end with one or more distal detents in the needle's lumen. A fiducial may include one or more splayed portions configured to engage the wall of the needle lumen, which may include one or more detents. The needle, which may include echogenic enhancements, may be configured to deliver a plurality of fiducials to a target location in serial fashion, one at a time. A variety of splayed-portion fiducials are disclosed.
摘要翻译：实施例包括基准展开系统，其包括针和通过摩擦接合保持在针内的至少一个展开端基准和/或通过所述展开端与针的内腔中的一个或多个远端棘爪的接合。基准可以包括被配置为接合针内腔的壁的一个或多个凸出部分，其可以包括一个或多个棘爪。可以包括回声增强的针可以被配置为以串联的方式一个一个地将多个基准传送到目标位置。公开了各种展开部分的基准。

3. 发明申请

WO2011094586A1 COLLAPSING STRUCTURE FOR REDUCING THE DIAMETER OF A STENT 审中-公开
标题翻译：用于减少直径的收缩结构
公开(公告)号：WO2011094586A1
公开(公告)日：2011-08-04
申请号：PCT/US2011/022987
申请日：2011-01-28
申请人： COOK MEDICAL TECHNOLOGIES LLC. , NEILAN, John , RYAN, Michael , WHITE, Sharon , LONG, Margaret , MCHUGO, Vincent
发明人： NEILAN, John , RYAN, Michael , WHITE, Sharon , LONG, Margaret , MCHUGO, Vincent
IPC分类号： A61F2/90 , A61F2/88
CPC分类号： A61F2/885 , A61F2/90 , A61F2002/9528 , A61F2230/0013 , A61F2230/005 , A61F2230/0071
摘要： A collapsing structure for collapsing the crowns of a stent and method of use thereof are described. The collapsing structure comprises an inner filament engaged to an outer filament. The outer filament is interwoven through at least a portion of the crowns of the stent end so as to create a plurality of loops. The inner filament is interwoven through at least a portion of the loops of the outer filament. Pulling on the inner filament causes the loops of the outer filament to be pulled radially inward, thereby pulling the crowns towards each other to collapse the stent end.
摘要翻译：描述了用于塌缩支架冠部的塌缩结构及其使用方法。塌缩结构包括与外部细丝接合的内部细丝。外部细丝穿过支架末端的冠部的至少一部分交织，从而形成多个环。内部细丝通过外部细丝的至少一部分环交织。拉动内部细丝导致外部细丝的环向径向向内拉动，从而将牙冠朝向彼此拉出以使支架端部折叠。

4. 发明申请

WO2011094527A1 MECHANICALLY EXPANDABLE DELIVERY AND DILATION SYSTEMS 审中-公开
标题翻译：机械可扩展的交付和放松系统
公开(公告)号：WO2011094527A1
公开(公告)日：2011-08-04
申请号：PCT/US2011/022903
申请日：2011-01-28
申请人： COOK MEDICAL TECHNOLOGIES LLC , MCHUGO, Vincent , NEILAN, John
发明人： MCHUGO, Vincent , NEILAN, John
IPC分类号： A61F2/84
CPC分类号： A61F2/966 , A61F2/95 , A61F2002/9505 , A61F2002/9511 , A61F2002/9517 , A61F2002/9534 , A61F2002/9665
摘要： A stent delivery system, a dilator system and a method for implanting a stent are provided. The stent delivery system includes an elongate shaft including a proximal portion, a distal portion, a lumen extending at least partially therethrough, and a stent receiving portion on the distal portion of the shaft. The stent delivery system also includes a stent positioned at the stent receiving portion of the elongate shaft, the stent having a constrained configuration and an expanded configuration. A proximal constraining member and a distal constraining member releasably connected to the stent and having a first position and a second position are also included. The proximal constraining member and the distal constraining member cooperatively apply longitudinal tensile force to at least a portion of the stent with the proximal and distal constraining members each in the first position.
摘要翻译：提供支架输送系统，扩张器系统和植入支架的方法。所述支架输送系统包括细长轴，所述细长轴包括近端部分，远端部分，至少部分地延伸穿过其中的内腔和所述轴的远侧部分上的支架接收部分。支架输送系统还包括定位在细长轴的支架接收部分的支架，支架具有约束构型和扩张构型。还包括近端约束构件和可释放地连接到支架并具有第一位置和第二位置的远端约束构件。近侧约束构件和远侧约束构件协同地将纵向张力施加到支架的至少一部分，其中近侧和远侧约束构件各自处于第一位置。

5. 发明申请

WO2012154351A1 APPARATUS FOR ACCURATELY CONTROLLING NEEDLE EXTENSION 审中-公开
标题翻译：精确控制针尖延伸的装置
公开(公告)号：WO2012154351A1
公开(公告)日：2012-11-15
申请号：PCT/US2012/032671
申请日：2012-04-09
申请人： COOK MEDICAL TECHNOLOGIES LLC. , DEVEREUX, Paul, David , LAVELLE, Shay, Joseph , NEILAN, John
发明人： DEVEREUX, Paul, David , LAVELLE, Shay, Joseph , NEILAN, John
IPC分类号： A61M5/46
CPC分类号： A61M5/46 , A61B17/3478 , A61B2017/00269 , A61B2090/034 , A61B2090/062 , A61B2090/3925 , A61B2090/3937 , A61M2005/3228
摘要： Devices are illustrated which provide for accurately controlling the extension of a needle (206) from a protective sheath (208) to increase accuracy and improve the outcome of the treatment procedure.
摘要翻译：示出了提供精确控制针（206）从保护套（208）的延伸的装置，以提高精度并改善治疗过程的结果。

6. 发明申请

WO2012099732A1 DELIVERY DEVICE 审中-公开
标题翻译：交货设备
公开(公告)号：WO2012099732A1
公开(公告)日：2012-07-26
申请号：PCT/US2012/020598
申请日：2012-01-09
申请人： COOK MEDICAL TECHNOLOGIES LLC , RYAN, Michael , NEILAN, John , O'SULLIVAN, Donagh , KEADY, Fionan
发明人： RYAN, Michael , NEILAN, John , O'SULLIVAN, Donagh , KEADY, Fionan
IPC分类号： A61F2/84
CPC分类号： A61F2/966 , A61F2002/9517 , A61F2002/9534
摘要： A delivery device for an intraluminal implant comprises a threaded driveshaft comprising a longitudinal axis, (ii) a gear mechamism comprising a lower gear set comprising at least one deployment gear and at least one resheathing gear sharing a common rotation axis, (iii) an upper gear set comprising a worm gear configured to perpendicularly translate rotation of a selected one of the at least one deployment gear or at least one resheathing gear with which it is engaged into rotation of the driveshaft about its longitudinal axis, (iv) an outer elongate shaft disposed slidably over an inner elongate shaft, the outer and inner elongate shafts comprising a mechanical communication connection with respectively a first portion and a second portion of the threaded drive shaft. The first portion of the threaded drive shaft is threaded opposite the second portion of the threaded drive shaft, so that the inner and outer shafts move in opposite longitudinal directions from each other upon rotation of the threaded drive shaft.
摘要翻译：用于管腔内植入物的输送装置包括具有纵向轴线的螺纹驱动轴，（ii）包括下齿轮组的齿轮机构，所述齿轮机构包括至少一个展开齿轮和共享共同旋转轴线的至少一个再转动齿轮，（iii）齿轮组包括蜗轮，所述蜗轮构造成垂直地平移所述至少一个展开齿轮中的所选择的一个或与其啮合的至少一个再转动齿轮的旋转，所述至少一个再转动齿轮与驱动轴绕其纵向轴线旋转，（iv）外部细长轴可滑动地布置在内细长轴上，外细长轴和内细长轴分别包括螺纹驱动轴的第一部分和第二部分的机械连通连接。螺纹驱动轴的第一部分与螺纹驱动轴的第二部分相对地螺纹连接，从而当螺纹驱动轴旋转时，内轴和外轴在彼此相反的纵向方向上移动。

7. 发明申请

WO2012151088A1 BIODEGRADABLE, BIOABSORBABLE STENT ANCHORS 审中-公开
标题翻译：生物可降解，生物可靠的固定锚
公开(公告)号：WO2012151088A1
公开(公告)日：2012-11-08
申请号：PCT/US2012/034884
申请日：2012-04-25
申请人： COOK MEDICAL TECHNOLOGIES LLC , NEILAN, John
发明人： NEILAN, John
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61F2/848 , A61F2/90 , A61F2/91 , A61F2/915 , A61F2002/072 , A61F2002/8483 , A61F2002/9534 , A61F2210/0004 , A61F2220/0016 , A61F2230/0054 , A61F2230/0078
摘要： Biodegradable/bioabsorbable stent anchors are provided to prevent stent migration and permit repositioning and/or removal of the stent after the anchors or portion thereof has sufficiently degraded or been absorbed.
摘要翻译：提供可生物降解/生物可吸收支架锚固件以防止支架移动，并且允许在锚固件或其部分已经充分降解或被吸收之后重新定位和/或移除支架。

8. 发明申请

WO2012099731A1 ROTARY AND LINEAR HANDLE MECHANISM FOR CONSTRAINED STENT DELIVERY SYSTEM 审中-公开
标题翻译：旋转和线性手柄机制用于约束式输送系统
公开(公告)号：WO2012099731A1
公开(公告)日：2012-07-26
申请号：PCT/US2012/020597
申请日：2012-01-09
申请人： COOK MEDICAL TECHNOLOGIES LLC , RYAN, Michael , NEILAN, John
发明人： RYAN, Michael , NEILAN, John
IPC分类号： A61F2/84
CPC分类号： A61F2/966 , A61F2002/9517 , A61F2002/9665
摘要： A stent delivery system is provided. The stent delivery system includes an elongate shaft including a proximal portion, a distal portion, a lumen extending at least partially therethrough, and a stent receiving portion on the distal portion of the shaft. The stent delivery system also includes a stent positioned at the stent receiving portion of the elongate shaft, the stent having a constrained configuration and an expanded configuration. A proximal constraining member and a distal constraining member releasably connected to the stent and having a first position and a second position are also included. The proximal constraining member and the distal constraining member cooperatively apply longitudinal tensile force to at least a portion of the stent with the proximal and distal constraining members each in the first position. A drive system configured to simultaneously move the proximal and distal constraining members is provided, the drive system including a threaded drive shaft (990) in mechanical communication with a rotatable handle (929).
摘要翻译：提供支架输送系统。所述支架输送系统包括细长轴，所述细长轴包括近端部分，远端部分，至少部分地延伸穿过其中的内腔和所述轴的远侧部分上的支架接收部分。支架输送系统还包括定位在细长轴的支架接收部分的支架，支架具有约束构型和扩张构型。还包括近端约束构件和可释放地连接到支架并具有第一位置和第二位置的远端约束构件。近侧约束构件和远侧约束构件协同地将纵向张力施加到支架的至少一部分，其中近侧和远侧约束构件各自处于第一位置。提供了构造成同时移动近侧和远侧约束构件的驱动系统，所述驱动系统包括与可旋转手柄（929）机械连通的螺纹驱动轴（990）。

9. 发明申请

WO2014058667A1 ROTARY SAMPLE-COLLECTION NEEDLE 审中-公开
标题翻译：旋转样品收集针
公开(公告)号：WO2014058667A1
公开(公告)日：2014-04-17
申请号：PCT/US2013/062981
申请日：2013-10-02
申请人： COOK MEDICAL TECHNOLOGIES LLC
发明人： NEILAN, John
IPC分类号： A61B10/02 , A61B17/34
CPC分类号： A61B10/0275 , A61B8/0841 , A61B10/0283 , A61B2017/3413 , A61B2090/3925
摘要： A rotary tissue-collection needle configured is provided with a closed distal tip and a distal aperture including a generally longitudinal cutting edge configured to excise tissue into the aperture for collection by rotation of the needle. The needle may be provided as part of a system including an outer sheath within which the needle may be rotated. The needle may be provided with echogenicity-enhancing features.
摘要翻译：构造的旋转组织收集针设置有封闭的远侧末端和远端孔，该远端孔包括大致纵向切割边缘，该切割边缘被配置为将组织切除到孔中以通过针的旋转进行收集。针可以设置为包括可以旋转针的外护套的系统的一部分。针可以具有回声增强特征。

10. 发明申请

WO2018081700A1 SUTURE ESOPHAGEAL STENT INTRODUCER 审中-公开
公开(公告)号：WO2018081700A1
公开(公告)日：2018-05-03
申请号：PCT/US2017/059018
申请日：2017-10-30
申请人： COOK MEDICAL TECHNOLOGIES LLC
发明人： McHUGO, Vincent , TREACY, Gerard , NEILAN, John , CAMPBELL, Triona , ANENDEN, Melissa , BHEALTUN, Criostoir O.
IPC分类号： A61F2/962 , A61F2/95 , A61F2/04 , A61F2/90
摘要： A stent delivery system includes an elongate shaft including a proximal portion, a distal portion, at least one lumen extending at least partially therethrough, and a stent receiving portion on the distal portion of the elongate shaft. A stent is positioned on the stent receiving portion of the elongate shaft, the stent having a first configuration and a second configuration. A proximal constraining arrangement is engaged with a proximal end of the stent. A distal constraining arrangement is engaged with a distal end of the stent. A release wire is disposed through the elongate shaft and releasably engaged with portion of the proximal constraining arrangement and the distal constraining arrangement member. A handle assembly is operably connected to the proximal constraining arrangement and the distal constraining arrangement, the handle assembly comprising a brake assembly. The proximal arrangement and the distal arrangement are coupled to the brake assembly of the handle.
摘要翻译：支架输送系统包括细长轴，该细长轴包括近端部分，远端部分，至少一个至少部分地穿过其延伸的内腔以及位于细长轴的远端部分上的支架接收部分。支架定位在细长轴的支架接收部分上，支架具有第一构造和第二构造。近端约束装置与支架的近端接合。远端约束装置与支架的远端接合。释放线穿过细长轴布置并且可释放地与近侧约束装置和远侧约束装置构件的部分接合。手柄组件可操作地连接到近端约束装置和远端约束装置，手柄组件包括制动组件。近端装置和远端装置连接到手柄的制动组件。

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