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1. 发明申请

WO2007059281A1 RAPID EXCHANGE BALLOON CATHETER AND METHOD FOR MAKING SAME 审中-公开
标题翻译：快速交换气泡导管及其制造方法
公开(公告)号：WO2007059281A1
公开(公告)日：2007-05-24
申请号：PCT/US2006/044495
申请日：2006-11-16
申请人： WILLIAM COOK EUROPE APS , COOK INCORPORATED , HANSEN, Palle, M. , AGGERHOLM, Steen
发明人： HANSEN, Palle, M. , AGGERHOLM, Steen
IPC分类号： A61M25/00
CPC分类号： A61M25/1036 , A61M25/0054 , A61M2025/0183 , Y10T156/10
摘要： A rapid exchange balloon catheter having a proximal end and a distal end, said catheter comprising: a tubular metal shaft body extending from the proximal end along a majority of the total length and having an inflation lumen arranged therein, a plastics distal end portion bonded to the metal body in extension thereof, said distal end portion being provided with an inflation lumen in communication with a balloon, and a guide wire lumen, said guide wire lumen extending from a proximal side port to a distal end opening. To reduce the resistance to kinking, the metal body comprises a transitional region having reduced stiffness at the position of bonding to the plastics distal end portion compared to a more proximal position along the metal body.
摘要翻译：一种具有近端和远端的快速交换气囊导管，所述导管包括：管状金属轴体，其从近端沿着总长度的大部分延伸并且具有布置在其中的充气腔，塑料远端部分粘合到所述远端部设置有与球囊连通的膨胀内腔和导丝管腔，所述导丝管腔从近侧端口延伸到远端开口。为了减少扭结的阻力，金属体包括与沿着金属体的更靠近的位置相比在结合到塑料远端部分的位置处的刚度降低的过渡区域。

2. 发明申请

WO2010121145A1 INTRODUCER ASSEMBLY 审中-公开
标题翻译：介绍大会
公开(公告)号：WO2010121145A1
公开(公告)日：2010-10-21
申请号：PCT/US2010/031413
申请日：2010-04-16
申请人： COOK INCORPORATED , WILLIAM COOK EUROPE ApS , HANSEN, Palle, M.
发明人： HANSEN, Palle, M.
IPC分类号： A61F2/84
CPC分类号： A61F2/95 , A61F2/07 , A61F2002/9517
摘要： An introducer assembly (40) for use in the deployment of implantable medical devices such as stents and stent grafts includes a carrier element (20), a dilator tip (18) located at the distal end of the carrier element (40) and sheath (32) movable between a device covering position and a device deployment position. In the device deployment position, a restricted annular gap (34) is created between the distal end (36) of the sheath (32) and the proximal end (38) of the dilator tip (18). The gap (34) is restricted by a restriction mechanism (50) located at the proximal, external end, of the introducer assembly (40). The gap (34) allows for the progressive deployment of the medical device from the introducer (40) and for simultaneous retraction of the dilator tip (18) thereby avoiding snagging of the dilator tip (18) against the wall of a patient's vessels and of the medical device.
摘要翻译：用于部署可植入医疗装置（例如支架和支架移植物）的导引器组件（40）包括载体元件（20），位于载体元件（40）的远端处的扩张器尖端（18）和护套 32）可在装置覆盖位置和装置展开位置之间移动。在设备展开位置中，在护套（32）的远端（36）和扩张器尖端（18）的近端（38）之间产生受限制的环形间隙（34）。间隙（34）由位于导引器组件（40）的近端外端的限制机构（50）限制。间隙（34）允许从导入器（40）逐渐展开医疗装置并且用于同时缩回扩张器尖端（18），从而避免扩张器尖端（18）阻塞患者血管的壁并且医疗器械。

3. 发明申请

WO2009033058A1 STENT, STENT GRAFT AND OTHER IMPLANTABLE ASSEMBLIES 审中-公开
标题翻译： STENT，STENT GRAFT和其他可植入组件
公开(公告)号：WO2009033058A1
公开(公告)日：2009-03-12
申请号：PCT/US2008/075450
申请日：2008-09-05
申请人： COOK INCORPORATED , WILLIAM COOK EUROPE ApS , HANSEN, Palle, M.
发明人： HANSEN, Palle, M.
IPC分类号： A61F2/90 , A61F2/84
CPC分类号： A61F2/86 , A61F2/848 , A61F2/95 , A61F2002/9511 , A61F2002/9665
摘要： A stent (100) or other implantable medical device is provided with one or more gripping shoulders (106) which are able, when the stent is compressed onto a delivery cannula (24) to frictionally mechanically engage the outer surface of the catheter (24) so as to grip thereon and maintatin the position of the stent (100) relative to the cannula during withdrawal of the covering sheath (32).
摘要翻译：支架（100）或其它可植入医疗装置设置有一个或多个夹紧肩部（106），当将支架压缩到输送套管（24）上以摩擦地机械接合导管（24）的外表面时，从而在退回覆盖护套（32）期间夹紧并维持支架（100）相对于套管的位置。

4. 发明申请

WO2010120670A1 INTRODUCER APPARATUS 审中-公开
标题翻译：介绍设备
公开(公告)号：WO2010120670A1
公开(公告)日：2010-10-21
申请号：PCT/US2010/030695
申请日：2010-04-12
申请人： COOK INCORPORATED , WILLIAM COOK EUROPE APS , HANSEN, Palle, M. , PARKER, Fred, T.
发明人： HANSEN, Palle, M. , PARKER, Fred, T.
IPC分类号： A61F2/84
CPC分类号： A61F2/966 , A61F2/95 , A61F2/97 , A61F2002/9517
摘要： A stent introducer apparatus comprises a sheath for surrounding a stent member, with the sheath having a longitudinal slit extending from one end along at least a substantial part of the length thereof, and a sheath withdrawal device comprising a reel for winding up the sheath. A second sheath may surround the slit portion of the sheath. An intermediate guide member can smooth the withdrawal procedure and flatten the sheath before it is wound on the reel. The intermediate guide member may include at least one of a second reel or a slot-defining member. The reel may be operated by means of a gear system. A method of deploying a stent member is also provided.
摘要翻译：支架引入装置包括用于围绕支架构件的护套，护套具有沿其长度的至少大部分的一端延伸的纵向狭缝，以及包括用于卷绕护套的卷轴的护套取出装置。第二护套可以围绕护套的狭缝部分。中间引导构件可以使护套平滑并且在将其卷绕在卷轴之前使其平坦化。中间引导构件可以包括第二卷轴或槽限定构件中的至少一个。卷轴可以通过齿轮系统来操作。还提供了展开支架构件的方法。

5. 发明申请

WO2010003070A1 DEPLOYMENT ASSEMBLY AND INTRODUCER 审中-公开
标题翻译：部署大会和介绍
公开(公告)号：WO2010003070A1
公开(公告)日：2010-01-07
申请号：PCT/US2009/049535
申请日：2009-07-02
申请人： COOK INCORPORATED , WILLIAM COOK EUROPE APS , HANSEN, Palle, M. , LOWINGER, Johan, M.
发明人： HANSEN, Palle, M. , LOWINGER, Johan, M.
IPC分类号： A61F2/84
CPC分类号： A61F2/95 , A61B2017/00367 , A61B2017/00371 , A61B2017/347 , A61F2/966 , A61F2002/9517
摘要： A deployment assembly (10) for an introducer used for introducing into a patient a stent or other device, the deployment assembly including a housing 30 carrying a sprung loaded (90) actuator (44,50). The actuator includes a toothed wheel (50) carrying a spool (48) around which a retraction strap (44) can be wound. The strap (44) is coupled to a body member (26) of the introducer and through this to the outer sheath (14) thereof. A trigger (16) is provided for operating the actuator (44, 50). When the trigger (16) is pressed, the actuator winds, under the force produced by the spring (90), the strap (44) to thereby retract the outer sheath (14) so as to expose and then deploy the device carried on the introducer. The mechanism is such that a surgeon need not expend his own energy to retract the outer sheath (14) since this force is provided by the spring (90). Furthermore, the spring (90) acts in a plane other than that of the direction of retraction of the sheath (14), which minimises the risk of inadvertent movement of the introducer as the sheath (14) is being retracted.
摘要翻译：一种用于导引器的展开组件（10），用于将支架或其他装置引入到患者中，所述展开组件包括承载弹簧加载（90）致动器（44,50）的壳体30。致动器包括带有卷轴（48）的带齿轮（50），围绕其缠绕收缩带（44）。带子（44）联接到导引器的主体部件（26）并通过其连接到其外护套（14）。提供了用于操作致动器（44,50）的触发器（16）。当触发器（16）被按压时，致动器在由弹簧（90）产生的力的作用下卷绕带子（44），从而缩回外护套（14），以便暴露并随后将携带在介绍人。该机构使得外科医生不需要花费自己的能量来缩回外护套（14），因为该力由弹簧（90）提供。此外，弹簧（90）作用在除了护套（14）的收缩方向以外的平面中，这最小化当护套（14）缩回时导入器的无意的移动的风险。

6. 发明申请

WO2007059276A1 MARKER FOR MARKING AN AREA IN BODY TISSUE 审中-公开
标题翻译：标记身体组织的标记
公开(公告)号：WO2007059276A1
公开(公告)日：2007-05-24
申请号：PCT/US2006/044485
申请日：2006-11-16
申请人： WILLIAM COOK EUROPE APS , COOK INCORPORATED , HANSEN, Palle, M.
发明人： HANSEN, Palle, M.
IPC分类号： A61B19/00
CPC分类号： A61B90/39 , A61B2017/00867 , A61B2090/3908
摘要： The invention relates to a marker for marking an area in body tissue, and a method for producing the marker. The marker is substantially rod-shaped with a first part having anchoring means intended to anchor the first part in body tissue in a body and a second part intended to substantially extend from the body while said first part is anchored in body tissue, and the marker comprises a super-elastic NiTi-alloy, and the bending stiffness of the first part is at least twice as high as the bending stiffness of the second part when the first part is anchored in body tissue.
摘要翻译：本发明涉及一种用于标记身体组织中的区域的标记，以及用于产生标记的方法。标记基本上是杆形的，其中第一部分具有锚定装置，其用于将身体组织中的第一部分锚定在主体中，并且第二部分旨在在所述第一部分锚定在身体组织中时从身体基本上延伸，并且标记包括超弹性NiTi合金，并且当第一部分锚定在身体组织中时，第一部分的弯曲刚度至少是第二部分的弯曲刚度的两倍。

7. 发明申请

WO2010120671A1 EVERTING DEPLOYMENT SYSTEM AND HANDLE 审中-公开
标题翻译：代表部署制度和手段
公开(公告)号：WO2010120671A1
公开(公告)日：2010-10-21
申请号：PCT/US2010/030696
申请日：2010-04-12
申请人： COOK INCORPORATED , WILLIAM COOK EUROPE APS , PARKER, Fred, T. , HANSEN, Palle, M.
发明人： PARKER, Fred, T. , HANSEN, Palle, M.
IPC分类号： A61F2/84
CPC分类号： A61F2/97 , A61F2/95 , A61F2/966 , A61F2002/9517 , A61F2002/9522 , A61F2250/0039 , A61L29/085
摘要： A stent deployment system, handle, and method of loading of a medical device are provided. The system includes an outer catheter having an inner liner extending past the end of the outer catheter and an inner catheter disposed within the outer catheter. The inner liner is inverted and attached to the inner catheter. Relative movement between the outer and the inner catheters can urge the inner liner to peel away from the medical device. A handle is disposed at the proximal end of the outer catheter, and may include a splitter configured to slice the wall of the tubular member. The handle may also include a rotatable mechanism that can be attached to the tubular member. Rotation of the rotatable mechanism retracts a portion of the tubular member into the handle and winds the sliced portion about the rotatable mechanism.
摘要翻译：提供了支架部署系统，手柄和装载医疗装置的方法。该系统包括具有延伸穿过外导管的端部的内衬套和设置在外导管内的内导管的外导管。内衬被倒置并连接到内导管上。外导管和内导管之间的相对运动可促使内衬从医疗装置剥离。手柄设置在外导管的近端处，并且可以包括被配置为切割管状构件的壁的分流器。手柄还可以包括可连接到管状构件的可旋转机构。可旋转机构的旋转将管状构件的一部分缩回到手柄中并围绕可旋转机构卷绕切片部分。

8. 发明申请

WO2009105176A2 COATED ENDOLUMINAL IMPLANT 审中-公开
标题翻译：包膜内膜植入物
公开(公告)号：WO2009105176A2
公开(公告)日：2009-08-27
申请号：PCT/US2009/000935
申请日：2009-02-13
申请人： WILLIAM COOK EUROPE APS , COOK INCORPORATED , HANSEN, Palle, M. , THYREGOD, Jesper
发明人： HANSEN, Palle, M. , THYREGOD, Jesper
IPC分类号： A61F2/86
CPC分类号： A61F2/86 , A61B17/12022 , A61B17/12118 , A61B2017/00526 , A61F2/01 , A61F2/07 , A61F2002/018 , A61F2002/068 , A61F2002/823 , A61F2230/0006 , A61F2230/0069 , A61F2250/0017 , A61F2250/0023 , A61L31/044
摘要： A stent structure (30) particularly for use in treating cerebral aneurysms is provided with a fibrous coating (34) which reduces the permeability of the underlying stent (32) to an extent that the flow through the stent structure is sufficiently suppressed to allow for resorbtion of an aneurysm while still providing sufficient flow through the stent structure to allow for flow into the perforator vessels. The fibrous coating may have different permeabilities in different zones of the underlying stent (32). The coating could be applied to other devices such as filters and occluders.
摘要翻译：特别是用于治疗脑动脉瘤的支架结构（30）设置有纤维涂层（34），其将下面的支架（32）的渗透性降低到通过支架结构的流动被充分抑制以允许再吸收的程度的动脉瘤，同时仍然提供足够的流动通过支架结构以允许流入穿孔血管。纤维涂层可能在下面的支架（32）的不同区域中具有不同的渗透性。涂层可以应用于其他设备，如过滤器和封堵器。

9. 发明申请

WO2009061882A1 METHOD AND APPARATUS FOR INTRODUCING EXPANDABLE INTRALUMINAL PROSTHESIS 审中-公开
标题翻译：用于引导可扩展的内镜治疗的方法和装置
公开(公告)号：WO2009061882A1
公开(公告)日：2009-05-14
申请号：PCT/US2008/082580
申请日：2008-11-06
申请人： COOK INCORPORATED , WILLIAM COOK EUROPE APS , HANSEN, Palle, M.
发明人： HANSEN, Palle, M.
IPC分类号： A61F2/84
CPC分类号： A61F2/95 , A61F2002/825 , A61F2250/0071 , A61M25/0668 , A61M2025/0188
摘要： A stent introducer (100) has a delivery sheath (60) positioned to restrain a self expandable stent (30). A pull wire (50a; 50b) is connected with the delivery sheath and extends through a pull wire lumen (41a, 41b) to enable remote retraction of the delivery sheath. The distal end of the pull wire lumen is associated with a region of weakness in the structure such that the region of weakness is torn on retraction of the delivery sheath.
摘要翻译：支架引入器（100）具有定位成限制自扩张支架（30）的输送护套（60）。拉线（50a; 50b）与输送护套连接并延伸穿过拉丝腔（41a，41b），以便远程收回输送护套。拉线管腔的远端与结构中的弱点相关联，使得在输送护套收缩时，无力区域被撕裂。

10. 发明申请

WO2007059277A1 CANNULA 审中-公开
标题翻译：插管
公开(公告)号：WO2007059277A1
公开(公告)日：2007-05-24
申请号：PCT/US2006/044486
申请日：2006-11-16
申请人： WILLIAM COOK EUROPE APS , COOK INCORPORATED , HANSEN, Palle, M.
发明人： HANSEN, Palle, M.
IPC分类号： A61M25/00 , A61M25/09 , A61M25/06 , A61B10/00 , A61B17/34
CPC分类号： A61L29/14 , A61B17/3421 , A61L29/02 , A61L2400/16 , A61M5/329 , C22F1/006 , C22F1/183
摘要： The invention relates to a cannula (1) for use in body tissue and body lumens and a method for producing the cannula. The cannula is substantially rod-shaped and has varying stiffness along its length. The cannula s divided into at least a first part (2) adapted to be located within body tissue or body lumens and a second part (3) adapted to extend from the body, and the cannula comprises a super elastic material that has been treated so the bending stiffness of the first part is different from the bending stiffness of the second part .
摘要翻译：本发明涉及一种用于身体组织和体腔的套管（1）和一种用于生产套管的方法。套管基本上是棒状的并且沿其长度具有变化的刚度。套管分成至少适合于位于身体组织或体腔内的第一部分（2）和适于从身体延伸的第二部分（3），并且套管包括已经被处理过的超弹性材料第一部分的弯曲刚度与第二部分的弯曲刚度不同。

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