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    • 3. 发明申请
    • A ROLLER
    • 滚刀
    • WO2005011356A1
    • 2005-02-10
    • PCT/GB2004/003167
    • 2004-07-21
    • HANCOCK, John
    • HANCOCK, John
    • A01B1/24
    • A01B1/24
    • A roller comprising a substantially cylindrical body (2) and a handle (3) pivotably attached to the body, the body (2) comprising a chamber (8) for containing a liquid, an outlet (16) in fluid communication with the chamber (8) and pump means (11) for dispensing a liquid from the chamber (2) through the outlet. The handle (3) may be detached from the body (2) of the roller and may house a hose. The roller may be used for multiple functions including a spray, a lawn aerator and lawn edger.
    • 一种辊,包括基本上圆柱形的主体(2)和可枢转地附接到主体的手柄(3),主体(2)包括用于容纳液体的腔室(8),与腔室流体连通的出口(16) 8)和用于通过出口从腔室(2)分配液体的泵装置(11)。 手柄(3)可以从辊的主体(2)分离并且可以容纳软管。 辊可用于多种功能,包括喷雾,草坪曝气机和草坪修整机。
    • 4. 发明申请
    • METHODS AND DEVICES FOR INTRAGASTRIC SUPPORT OF FUNCTIONAL OR PROSTHETIC GASTROINTESTINAL DEVICES
    • 用于功能性或前置性胃肠道装置的肠内支持的方法和装置
    • WO2008154450A1
    • 2008-12-18
    • PCT/US2008/066214
    • 2008-06-06
    • VALENTX, INC.SWAIN, Christopher, PaulDANN, MitchellFLUET, GregHANCOCK, JohnVON HOFFMANN, GerardWRIGHT, James
    • SWAIN, Christopher, PaulDANN, MitchellFLUET, GregHANCOCK, JohnVON HOFFMANN, GerardWRIGHT, James
    • A61M31/00
    • A61F5/0076A61J15/0003A61J15/003A61J15/0049A61J15/0069A61J15/0084A61M31/00
    • Disclosed herein are systems and methods for attaching or maintaining the position of a therapeutic or diagnostic device in a body lumen, such as the GI tract without necessarily requiring any penetrating attachments through any body walls. The system can include at least two elements: a proximal orientation element (500) and a distal support element (502). The proximal orientation element (500) can be configured to reside at least partially within the esophageal lumen and the distal support element (502) can be configured to reside in the stomach, such as along the greater curve of the stomach. An intragastric support system (501) can have a first configuration (501) in which the long axis of the proximal orientation element is substantially parallel and/or substantially coaxial with the long axis of the distal support element, and a second configuration (501 ') in which the long axis of the proximal orientation element (500) is not substantially coaxial with the long axis of the distal support element (502). The second configuration (50F) can thus advantageously retain the intragastric support system (501) in place and prevent unwanted proximal migration of the distal support element (502) into the esophagus or distal migration into the intestine.
    • 本文公开了用于将治疗或诊断装置的位置附接或维持在诸如GI道的体腔中的系统和方法,而不需要通过任何身体壁的任何穿透附着物。 该系统可以包括至少两个元件:近端定向元件(500)和远侧支撑元件(502)。 近端取向元件(500)可被配置为至少部分地位于食管腔内,并且远端支撑元件(502)可被配置为驻留在胃中,例如沿着胃的较大曲线。 胃内支撑系统(501)可以具有第一构造(501),其中近侧定向元件的长轴基本上与远侧支撑元件的长轴平行和/或基本同轴,并且第二构造(501' ),其中近端定向元件(500)的长轴基本上与远端支撑元件(502)的长轴同轴。 因此,第二配置(50F)可以有利地将胃内支持系统(501)保持在适当位置并且防止远端支撑元件(502)的不希望的近端迁移进入食道或远端迁移到肠内。
    • 6. 发明申请
    • HIGH SPECIFIC GRAVITY INTRAGASTRIC DEVICE
    • 高特异度输入装置
    • WO2010075482A2
    • 2010-07-01
    • PCT/US2009/069351
    • 2009-12-22
    • HANCOCK, John
    • HANCOCK, John
    • A61M29/00A61F2/04A61L27/52A61L27/04A61L27/14
    • A61F5/0036A61F5/003
    • The teachings are directed to an intragastric device comprising a flexible and expandable bladder having a predetermined shape upon expansion for contacting the antrum of the stomach of a subject. The device is designed to avoid passage of any part of the device beyond the pylorus and lower esophageal sphincter while the bladder is expanded during use. In these embodiments, the bladder can contain a high specific gravity material when expanded; wherein, the high specific gravity material contributes to an in vivo specific gravity of the device that ranges from about 1.2 g/ml to about 2.1 g/ml and functions to direct the device to the pyloric antrum of the subject during use of the device. Moreover, these embodiments can include a filling material comprising a biocompatible fluid component and a hydrogel component to make the device substantially leakproof and contribute to the in vivo specific gravity of the device.
    • 该教导涉及一种胃内装置,其包括在膨胀时具有预定形状的柔性和可膨胀囊,用于接触受试者胃的胃窦。 该装置被设计成在使用过程中膀胱膨胀时避免设备的任何部分超过幽门和食管下括约肌。 在这些实施例中,当膨胀时,气囊可以包含高比重材料; 其中,所述高比重物质有助于所述装置的体内比重为约1.2g / ml至约2.1g / ml,并且用于在使用所述装置期间将所述装置引导至所述受试者的幽门窦。 此外,这些实施方案可以包括包含生物相容性流体组分和水凝胶组分的填充材料,以使得该装置基本上防漏并有助于该装置的体内比重。
    • 7. 发明申请
    • COMPOUNDS FOR USE IN THE TREATMENT OF PLANTS
    • 化合物用于处理植物
    • WO2012042227A1
    • 2012-04-05
    • PCT/GB2011/001433
    • 2011-09-30
    • PENINSULA COLLEGE OF MEDICINE AND DENTISTRY, UNIVERSITY OF EXETERWHITEMAN, MatthewHANCOCK, JohnWILSON, IanLISJAK, Miroslav
    • WHITEMAN, MatthewHANCOCK, JohnWILSON, IanLISJAK, Miroslav
    • A01N57/32A01N59/02A01P21/00
    • A01N59/02A01N57/32
    • The invention relates to use of a compound in a treatment of a plant to promote plant growth wherein the compound is a salt comprising an anion of formula (1): or a conjugate acid thereof, wherein: R 1 , R 2 , R 3 , R 4 and R 5 are each independently selected from H, halogen, optionally substituted C 1 -C 10 alkyl, optionally substituted C 2 -C 10 alkenyl, optionally substituted C 2 - C 10 alkynyl, optionally substituted C 3 -C 10 cycloalkyl, optionally substituted C 3 -C 10 cycloalkenyl, optionally substituted C3-Ci0 cycloalkynyl, hydroxy, optionally substituted C 1 -C 10 alkoxy, amino, mono-(C 1 -C 10 alkyl)amino and di-(C 1 -C 10 alkyl)amino groups; and Y is a nitrogen containing heterocyclyl group having from 3 to 14 ring atoms, a nitrogen containing heteroaryl group having from 3 to 14 ring atoms, an optionally substituted mono-(C 1 -C 10 alkyl)amino group, an optionally substituted di-(C 1 -C 10 alkyl)amino group or an optionally substituted tri-(C 1 -C 10 alkyl)amino group. The compounds can be used to prevent or reduce stomatal closure or to cause stomatal opening in a plant. The invention further provides compounds for use in a herbicidal treatment of a plant. New compounds and a method for their manufacture are also described.
    • 本发明涉及化合物在处理植物中促进植物生长的用途,其中化合物是包含式(1)的阴离子或其共轭酸的盐,其中:R1,R2,R3,R4和R5 任选取代的C 2 -C 10烯基,任选取代的C 2 -C 10炔基,任选取代的C 3 -C 10炔基,任选取代的C 3 -C 10环烷基,任选取代的C 3 -C 10环烯基,任选取代的C 3 -C 10环炔基 ,羟基,任选取代的C 1 -C 10烷氧基,氨基,单(C 1 -C 10烷基)氨基和二 - (C 1 -C 10烷基)氨基; 并且Y是具有3至14个环原子的含氮杂环基,具有3至14个环原子的含氮杂芳基,任选取代的单(C 1 -C 10烷基)氨基,任选取代的二 - (C1 -C 10烷基)氨基或任选取代的三 - (C 1 -C 10烷基)氨基。 该化合物可用于预防或减少气孔关闭或引起植物气孔开放。 本发明还提供用于植物除草处理的化合物。 还描述了新的化合物及其制备方法。