会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 5. 发明申请
    • COMPARTMENTAL EXTRACT COMPOSITIONS FOR TISSUE ENGINEERING
    • 用于组织工程的分层提取物组合物
    • WO2009098698A3
    • 2010-04-22
    • PCT/IL2009000147
    • 2009-02-08
    • COHEN SHAHAR
    • COHEN SHAHAR
    • A61L27/36A61L27/38
    • A61L27/3604A61K35/00A61L27/38C12M25/14C12M35/04
    • The present invention concerns biologically-active cell-free scaffolds composed of extracts of cellular and/or extracellular compartments for use in tissue regeneration. The present invention also contemplates the novel concept of redesigning the biological scaffold by seeding cells thereon followed by cell elimination. Cells are seeded on the scaffold for a period of time during which a dynamic interaction occurs between the scaffold and the seeded cells, resulting in reshaping of the scaffold architecture and integration of newly synthesized matrix elements. Redesigning may improve the physical and biological characteristics of the scaffold, and also improve the matching of the scaffold to treat a specific target tissue or a specific patient, by seeding tissue-specific cells or by seeding cells which are autologous to a patient, respectively.
    • 本发明涉及由用于组织再生的细胞和/或细胞外区室的提取物组成的生物活性无细胞支架。 本发明还考虑了通过在其上接种细胞并随后进行细胞消除来重新设计生物支架的新概念。 将细胞接种在支架上一段时间,在此期间在支架和接种的细胞之间发生动态相互作用,导致重建骨架结构并整合新合成的基质元件。 重新设计可以改善支架的物理和生物学特性,并且还通过分别接种组织特异性细胞或通过分别接种患者自体的细胞来改善支架的匹配以治疗特定靶组织或特定患者。