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1. 发明申请

WO2006001582A1 CELL-KILLING PEPTIDE 审中-公开
标题翻译：细胞杀死肽
公开(公告)号：WO2006001582A1
公开(公告)日：2006-01-05
申请号：PCT/KR2005/000827
申请日：2005-03-22
申请人： CHOSUN UNIVERSITY , KIM, Tae Hyoung
发明人： KIM, Tae Hyoung
IPC分类号： C07K7/06
CPC分类号： C07K14/4747 , A61K38/00 , C07K2319/00
摘要： The present invention relates a novel cell-killing peptide, particularly to a cell-killing peptide that exploits a specific legion at the C-terminus of Noxa protein, a "BH3-only" member of Bcl-2 family causing apoptosis and fusion proteins containing the same. According to the present invention, the cell-killing peptide (CKP) effectively kills a cancer cell such as HeLa or HCT116 when it is conjugated with PTD or CTD domain. Therefore, the cell-killing peptide of the present invention is still stronger to kill cells, compared with conventional substances such as TRAIL, and will be applied widely for various cell therapies, especially in cancer treatment.
摘要翻译：本发明涉及一种新型杀细胞肽，特别涉及一种利用Noxa蛋白C末端的特定部位的细胞杀伤肽，一种引起凋亡的Bcl-2家族的“仅BH3”成员和含有一样。根据本发明，当与PTD或CTD结构域结合时，细胞杀伤肽（CKP）有效地杀死诸如HeLa或HCT116之类的癌细胞。因此，与常规物质如TRAIL相比，本发明的细胞杀伤肽比杀伤细胞更强，并且将广泛应用于各种细胞疗法，特别是在癌症治疗中。

2. 发明申请

WO2008130158A1 A BIODEGRADABLE MICROSPHERE COMPOSITION SUITABLE FOR THE CONTROLLED RELEASE OF GLUCOSE CONTROLLING PEPTIDE AND FORMULATION THEREOF 审中-公开
标题翻译：用于控制释放葡萄糖控制肽的生物可降解微球组合物及其制剂
公开(公告)号：WO2008130158A1
公开(公告)日：2008-10-30
申请号：PCT/KR2008/002216
申请日：2008-04-18
申请人： DONG-A PHARMACEUTICAL. CO., LTD , KWAK, Hyun Hee , LEE, Ghun Il , PARK, Yong Man , SON, Mi Kyung , YANG, Hi Chang , KIM, Tae Hyoung , KIM, Yoon Ji , KIM, Byong Moon , LEE, Sung Hee , KANG, Soo Hyung , YOO, Moohi
发明人： KWAK, Hyun Hee , LEE, Ghun Il , PARK, Yong Man , SON, Mi Kyung , YANG, Hi Chang , KIM, Tae Hyoung , KIM, Yoon Ji , KIM, Byong Moon , LEE, Sung Hee , KANG, Soo Hyung , YOO, Moohi
IPC分类号： A61K9/52
CPC分类号： A61K9/1647 , A61K38/26 , Y02A50/465
摘要： Disclosed are biodegradable microspheres, capable of releasing a glucose-regulating peptide in a controlled manner, comprising a biodegradable polymer carrier with the glucose-regulating peptide encapsulated therein, and methods for the preparation thereof. In addition to ensuring high encapsulation efficiency and high stability of the encapsulated drug, the microspheres shows neither an initial burst effect nor incomplete release and allows the zero-order release of drugs over a prolonged period of time, thus improving the therapeutic effect of the drug.
摘要翻译：公开了能够以受控方式释放葡萄糖调节肽的生物可降解微球，其包含其中包含葡萄糖调节肽的生物可降解聚合物载体及其制备方法。除了确保包封药物的高封装效率和高稳定性之外，微球体既不显示初始爆发效应也不显示不完全释放，并允许药物在较长时间内零次释放，从而改善药物的治疗效果。

3. 发明申请

WO2004071965A1 STERILIZE VALVE AND A WATER-PURIFYING DEVICE USING THE SAME 审中-公开
标题翻译：灭菌阀和使用该灭菌器的水净化装置
公开(公告)号：WO2004071965A1
公开(公告)日：2004-08-26
申请号：PCT/KR2004/000273
申请日：2004-02-11
申请人： KIM, Kyoung Mok , KIM, Tae Hyoung
发明人： KIM, Kyoung Mok , KIM, Tae Hyoung
IPC分类号： C02F1/32
CPC分类号： C02F1/325 , B67D3/0029 , B67D2001/0089 , B67D2210/00015 , C02F1/001 , C02F1/283 , C02F2201/3223 , C02F2307/06
摘要： The present invention relates to a sterilizing tap and a water-purifying device using the sterilizing tap. The sterilizing tap includes a tap body having a waterway connector connected to a waterway formed at its side, a screw hole formed at its top, and an outlet formed at its bottom; and a sterilizing unit, wherein the sterilizing unit includes a bolt unit coupled to the screw hole, an ultraviolet ray generator disposed within the tap body when the bolt unit is coupled to the screw hole, for generating ultraviolet rays, and a first quartz tube sealed to the bolt unit to completely surround the ultraviolet ray generator. The water-purifying device includes a first room formed at one side of the water-purifying device body and having a waterway through spring water is supplied from the water tank; a sterilizing tap communicated with the waterway, for sterilizing spring water and discharging the sterilized spring water; a second room formed at the other side of the water-purifying device body, wherein cups are provided in the second room; and doors installed in the first room and/or the second room, for preventing the sterilizing tap and/or the cups from being contaminated by external contamination sources.
摘要翻译：本发明涉及灭菌龙头和使用灭菌龙头的净水装置。灭菌龙头包括：龙头本体，其具有连接到其侧面形成的水路的水路连接器，在其顶部形成的螺纹孔和在其底部形成的出口; 以及灭菌单元，其中所述消毒单元包括联接到所述螺钉孔的螺栓单元，当所述螺栓单元联接到所述螺钉孔以产生紫外线时设置在所述龙头本体内的紫外线发生器，以及密封的第一石英管到螺栓单元以完全包围紫外线发生器。净水装置包括形成在净水装置主体的一侧并且具有通过泉水的水路的第一室从水箱供给; 与水路连通的消毒水龙头，用于灭菌泉水和排出灭菌的泉水; 形成在净水装置主体的另一侧的第二室，其中在第二室中设置有杯子; 以及安装在第一房间和/或第二房间中的门，用于防止消毒龙头和/或杯被外部污染源污染。

4. 发明申请

WO2010147264A1 METHOD OF EXCHANGING MESSAGES AND TRANSMITTING AND RECEIVING DEVICES 审中-公开
标题翻译：交换信息和发送和接收设备的方法
公开(公告)号：WO2010147264A1
公开(公告)日：2010-12-23
申请号：PCT/KR2009/005237
申请日：2009-09-15
申请人： LG ELECTRONICS INC. , KIM, Taek Soo , CHO, Duk Ho , KIM, Tae Hyoung
发明人： KIM, Taek Soo , CHO, Duk Ho , KIM, Tae Hyoung
IPC分类号： H04L12/58 , H04L29/06
CPC分类号： H04W24/08 , H04L45/121 , H04L45/308 , H04W24/10
摘要： A method of exchanging a round trip time between a transmitting device and a receiving device in a wireless network comprises receiving an echo request command from an audio video control (AVC) layer to a medium access control (MAC) layer, the echo request command including a first identifier for identifying the transmitting device, a second identifier for identifying the receiving device, and a third identifier; transferring a MAC message from the MAC layer to a physical layer, the MAC message including a message preamble, a message type, and the echo request command; transmitting a first physical layer data unit to the receiving device, the first physical layer data unit including at least one header, the MAC message, and audio/video (A/V) data; and receiving a second physical layer data unit from the receiving device, the second physical layer data unit including an echo report command in response to the echo request command, the echo report command including the third identifier.
摘要翻译：一种在无线网络中的发送装置与接收装置之间交换往返时间的方法包括从音频视频控制（AVC）层接收到媒体接入控制（MAC）层的回波请求命令，所述回波请求命令包括用于识别发送设备的第一标识符，用于标识接收设备的第二标识符和第三标识符; 将MAC消息从MAC层传送到物理层，所述MAC消息包括消息前导码，消息类型和回显请求命令; 将第一物理层数据单元发送到所述接收设备，所述第一物理层数据单元包括至少一个报头，所述MAC消息和音频/视频（A / V）数据; 以及从所述接收设备接收第二物理层数据单元，所述第二物理层数据单元响应于所述回声请求命令包括回声报告命令，所述回声报告命令包括所述第三标识符。

5. 发明申请

WO2005021441A1 AN APPARATUS FOR PURIFYING AND STERILIZING 审中-公开
标题翻译：用于净化和灭菌的装置
公开(公告)号：WO2005021441A1
公开(公告)日：2005-03-10
申请号：PCT/KR2004/002167
申请日：2004-08-28
申请人： KIM, Tae Hyoung
发明人： KIM, Tae Hyoung
IPC分类号： C02F1/32
CPC分类号： C02F9/00 , C02F1/32 , C02F1/325 , C02F1/4606 , C02F1/722 , C02F1/725 , C02F1/78 , C02F2201/3222 , C02F2201/3226
摘要： The present invention relates to a sterilization and purification apparatus. The apparatus comprises a pair of fixed units (61, 62) that are spaced apart by a plurality of support rods (63); an introduction pipe body (10) in which an inflow port (11) into which a treated water is introduced is formed, and an exhaust port body (20) in which an exhaust port (21) from which purified water is exhausted is formed, wherein the introduction pipe body (10) and the exhaust port body (20) are each disposed in the fixed units (61, 62); a plurality of treatment chemical input valves (31, 32, 33) and (34) into which various treatment chemicals ar inputted; an ultraviolet generating means (40) disposed between the introduction pipe body (10) and the exhaust port body 820); and tube (50) that communicate with the introduction pipe body (10) and the exhaust port body (20), wherein the tubes are disposed to wind the ultraviolet generating means (40).
摘要翻译：本发明涉及灭菌和净化装置。该装置包括由多个支撑杆（63）隔开的一对固定单元（61,62）。其中形成有经过处理的水被引入的流入口（11）的导入管体（10）和形成有净化水排出的排气口（21）的排气口主体（20）其特征在于，所述导入管体（10）和所述排气口主体（20）分别配置在所述固定部（61,62）中。多种处理化学品输入阀（31,32,33）和（34），其中输入各种处理化学品; 设置在引入管体（10）和排气口主体820之间的紫外线发生装置（40）; 以及与引入管体（10）和排气口主体（20）连通的管（50），其中所述管设置成卷绕紫外线发生装置（40）。

6. 发明申请

WO2005014025A1 FORMULATION OF ALBUMIN-FREE ERYTHROPOIETIN 审中-公开
标题翻译：无氨基硫蛋白的配方
公开(公告)号：WO2005014025A1
公开(公告)日：2005-02-17
申请号：PCT/KR2004/001891
申请日：2004-07-27
申请人： CJ CORP. , CHO, Cheong Weon , CHUNG, Soon Kwan , KU, Jeong , CHEON, Jun Hee , AN, Tae Kun , JEON, Eun Kyung , KO, Jae Kyoung , KIM, Tae Hyoung , BEAK, Yeong Ok , SUH, Hea Ran
发明人： CHO, Cheong Weon , CHUNG, Soon Kwan , KU, Jeong , CHEON, Jun Hee , AN, Tae Kun , JEON, Eun Kyung , KO, Jae Kyoung , KIM, Tae Hyoung , BEAK, Yeong Ok , SUH, Hea Ran
IPC分类号： A61K38/18
CPC分类号： A61K38/1816 , A61K9/0019 , A61K47/183 , A61K47/36
摘要： Disclosed is a stable pharmaceutical solution preparation of erythropoietin (EPO), which includes a stabilizing agent not containing a blood-derived protein, thereby maintaining EPO activity for a prolonged period of time without the risk of viral contamination. The stable solution preparation further includes a non-ionic surfactant and a tonicity agent, thereby preventing EPO loss during storage and facilitating administration to the body.
摘要翻译：公开了稳定的促红细胞生成素（EPO）的药物溶液制剂，其包括不含血液衍生蛋白质的稳定剂，从而在长时间内保持EPO活性而没有病毒污染的风险。稳定的溶液制剂还包括非离子表面活性剂和张力剂，从而防止EPO在储存过程中的损失并促进对体内的给药。

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