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1. 发明申请

WO2007079257A2 INTEGRATED DISSOLUTION PROCESSING AND SAMPLE TRANSFER SYSTEM 审中-公开
标题翻译：综合解决方案处理和样品转移系统
公开(公告)号：WO2007079257A2
公开(公告)日：2007-07-12
申请号：PCT/US2006/049664
申请日：2006-12-28
申请人： CALIPER LIFE SCIENCES, INC. , KENNEDY, Colin, B. , VON BEHREN, Dale , HUSAIN, Syed , BERNAL, Rick
发明人： KENNEDY, Colin, B. , VON BEHREN, Dale , HUSAIN, Syed , BERNAL, Rick
CPC分类号： G01N1/38 , G01N13/00 , G01N33/15 , G01N35/025 , G01N2013/003 , G01N2013/006 , G01N2035/00198
摘要： The invention provides a system and method for dissolution testing. The system (100) includes multiple dissolution vessels (110) and a dose carrier (130) positioned above the dissolution vessels. The dose carrier holds multiple removable carousels (132) that receive individual doses for dissolution tested. Carousels that receive tablets or sinkers typically have a first configuration (132a), while carousels that receive baskets typically have a second configuration (132b). The two different configurations of carousels are interchangeable on the same dose ring. The system further includes a drive head positioned above the dose carrier, the drive head having a basket arbor (142) and a mixing paddle (143) removably and interchangeably attached. A sample transfer device (170) integral with the system transfers sample aliquots having volumes in the range of 50 μl to 1 ml from the dissolution vessels to wells (182) of an external receptacle (180).
摘要翻译：本发明提供了用于溶出度测试的系统和方法。系统（100）包括多个溶解容器（110）和位于溶解容器上方的剂量载体（130）。剂量载体保持多个可移除转盘（132），其接收用于溶出度测试的各个剂量。接收片剂或沉降片的转盘通常具有第一配置（132a），而接收篮子的转盘通常具有第二配置（132b）。转盘的两种不同配置可在相同的剂量环上互换。所述系统还包括位于所述剂量载体上方的驱动头，所述驱动头具有可移除地且可互换地连接的篮筐（142）和混合桨（143）。与系统整合的样品转移装置（170）将具有从溶解容器到体积为50μl至1ml的体积的样品等分试样转移到外部容器（180）的孔（182）。

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