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    • 4. 发明申请
    • TUNABLE BIO-FUNCTIONALIZED NANOELECTROMECHANICAL SYSTEMS HAVING SUPERHYDROPHOBIC SURFACES FOR USE IN FLUIDS
    • 具有超疏水表面的可生物生物功能化纳米电子机械系统用于流体
    • WO2009008915A2
    • 2009-01-15
    • PCT/US2008003719
    • 2008-03-20
    • UNIV BOSTONEKINCI KAMIL LYAKHOT VICTOR
    • EKINCI KAMIL LYAKHOT VICTOR
    • G01N27/00G01N33/543G01Q30/14G01Q60/42G01Q60/52
    • G01N29/036G01N2291/0256
    • Tunable, bio-functionalized, nanoelectromechanical systems (Bio-NEMS), micromechanical resonators (MRs), nanomechanical resonators (NRs), surface acoustic wave resonators, and bulk acoustic wave resonators having superhydrophobic surfaces for use in aqueous biochemical solutions. The MRs, NRs or Bio-NEMS include a system resonator that can vibrate or oscillate at a relatively high frequency and to which an analyte molecule (s) contained in the solution can attach or upon which small molecular- scale forces can act; a device for adjusting a relaxation time of the solution, to increase the quality (Q- factor) of the resonator inside the solution, to reduce energy dissipation into the solution; and a device for detecting a frequency shift in the resonator due to the analyte molecule (s) or applied molecular-scale forces. The resonator can include roughness elements that provide superhydrophobicity and, more particularly, gaps between adjacent asperities for repelling the aqueous solution from the surface of the device.
    • 纳米机电系统(Bio-NEMS),微机械谐振器(MR),纳米机械谐振器(NR),表面声波谐振器和具有用于水性生物化学溶液的超疏水表面的体声波谐振器。 MR,NR或Bio-NEMS包括一个系统谐振器,它可以以相对较高的频率振动或振荡,并且溶液中包含的分析物分子可以附着在该系统谐振器上,或者小分子尺度的力可以作用于其上; 用于调节溶液弛豫时间的装置,用于提高溶液内谐振器的质量(Q因数),以减少进入溶液的能量耗散; 以及用于检测由于分析物分子或施加的分子尺度力而引起的谐振器中的频移的装置。 谐振器可以包括提供超疏水性的​​粗糙元件,并且更具体地,包括用于从装置的表面排斥水溶液的相邻粗糙体之间的间隙。