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1. 发明申请

WO2012008782A3 USE OF CARBON NANOTUBES FOR PREVENTING OR TREATING BRAIN DISEASE 审中-公开
标题翻译：碳纳米管在预防或治疗脑部疾病中的应用
公开(公告)号：WO2012008782A3
公开(公告)日：2012-05-18
申请号：PCT/KR2011005200
申请日：2011-07-14
申请人： BRAINGUARD CO LTD , JEONG YOONHWA , LEE HYUN JUNG , LEE DO YEON , NOH YOO HUN , KIM DO HEE , KIM OK HYEON , PARK JI AE , LEE JIWON
发明人： JEONG YOONHWA , LEE HYUN JUNG , LEE DO YEON , NOH YOO HUN , KIM DO HEE , KIM OK HYEON , PARK JI AE , LEE JIWON
IPC分类号： A61K47/02 , A61K33/00 , A61P25/00 , A61P25/28
CPC分类号： A61K33/44 , A61B5/04001 , A61B5/04002 , A61B5/4082 , A61B5/4848 , A61K9/0092 , A61K31/166 , A61K31/192 , A61K31/235
摘要： The present invention relates to the use of carbon nanotubes for preventing or treating brain disease, and more particularly, to a composition for protecting cranial nerves, to a composition for preventing or treating neurodegenerative diseases or ischemic brain disease or to a composition for treating traumatic injuries to the central nervous system, containing carbon nanotubes as an active ingredient, to the use of carbon nanotubes for preparing a therapeutic agent for the abovementioned diseases and to a method for treating the abovementioned diseases. The composition of the present invention enables patients to recover from physical damage to the brain, exhibits superior efficacy for inhibiting the onset of Parkinson's disease and strokes in animal models for Parkinson's disease and strokes, and the cytotoxic effects of beta amyloid in beta amyloid toxicity tests. Therefore, the composition of the present invention can be effectively used in the preparation of medicine for protecting cranial nerves, therapeutic agents for preventing or treating brain disease, or therapeutic agents for treating traumatic injuries to the central nervous system.
摘要翻译：本发明涉及碳纳米管用于预防或治疗脑部疾病的用途，更具体地涉及用于保护颅神经的组合物，涉及用于预防或治疗神经变性疾病或缺血性脑疾病的组合物或用于治疗创伤性损伤的组合物涉及含有碳纳米管作为活性成分的中枢神经系统，涉及使用碳纳米管制备用于上述疾病的治疗剂以及治疗上述疾病的方法。本发明的组合物使患者能够从对大脑的物理损伤中恢复，在帕金森病和中风的动物模型中显示出优越的抑制帕金森氏病和中风发作的功效，并且在β淀粉样蛋白毒性试验中β淀粉样蛋白的细胞毒性作用。因此，本发明的组合物可以有效地用于制备用于保护颅神经的药物，用于预防或治疗脑疾病的治疗剂或用于治疗中枢神经系统创伤的治疗剂。

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