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1. 发明申请

WO2009085206A3 PERCUTANEOUS HEART VALVE, SYSTEM, AND METHOD 审中-公开
公开(公告)号：WO2009085206A3
公开(公告)日：2009-07-09
申请号：PCT/US2008/013888
申请日：2008-12-19
申请人： BOSTON SCIENTIFIC SCIMED, INC. , KVEEN, Graig, L. , JENSON, Mark, L. , THIELEN, Joseph, M. , DRASLER, William, J. , EIDENSCHINK, Tracee, E.J.
发明人： KVEEN, Graig, L. , JENSON, Mark, L. , THIELEN, Joseph, M. , DRASLER, William, J. , EIDENSCHINK, Tracee, E.J.
IPC分类号： A61F2/24
摘要： Devices, systems, and methods are provided to treat diseased cardiac valves. The device includes a percutaneous heart valve (100) having an expandable valve frame (102) including valve frame members (105), a valve leaflet (132) coupled to the valve frame, and an expandable stent anchoring frame (104) coupled to the valve frame including stent frame members (106) defining a first portion (108) and a second portion (110) having greater flexibility than the first portion, where the first portion and the valve frame define a length, and where the stent frame members and the valve frame members along the length provide a contiguous surface over which a delivery device can repeatedly slide over the length in its entirety in two longitudinal directions when the first portion and the valve frame are in a partially expanded state during delivery from the delivery device.

2. 发明申请

WO2008097556A1 SYSTEMS AND METHODS FOR VALVE DELIVERY 审中-公开
标题翻译：阀门输送系统及方法
公开(公告)号：WO2008097556A1
公开(公告)日：2008-08-14
申请号：PCT/US2008/001537
申请日：2008-02-05
申请人： BOSTON SCIENTIFIC SCIMED, INC. , JENSON, Mark, L. , DRASLER, William, J. , HILL, Jason, P. , THIELEN, Joseph, M.
发明人： JENSON, Mark, L. , DRASLER, William, J. , HILL, Jason, P. , THIELEN, Joseph, M.
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/013 , A61F2/243 , A61F2/2433 , A61F2/2475 , A61F2002/018 , A61F2220/005 , A61F2220/0058 , A61F2220/0066 , A61F2230/0006 , A61F2230/0069 , A61F2250/0059
摘要： A system (100) having an elongate delivery catheter (102), an elongate mesh body (104) including an expandable region positioned around at least a portion of the elongate delivery catheter, a retractable member (130) that extends through the elongate delivery catheter to connect to the elongate mesh body, where the retractable member moves to radially expand the expandable region of the elongate mesh body from an undeployed state to an intermediate state. The system also includes a valve (106) positioned around at least a portion of the elongate delivery catheter position, and a filter (108) positioned around at least a portion of the elongate delivery catheter to filter and control fluid flow.
摘要翻译：一种具有细长输送导管（102）的系统（100），包括位于细长输送导管的至少一部分周围的可扩张区域的细长网状体（104），延伸穿过细长输送导管以连接到细长网状体，其中可伸缩构件移动以将细长网状体的可扩张区域从未部署状态径向扩展到中间状态。该系统还包括围绕细长输送导管位置的至少一部分定位的阀（106）和围绕细长输送导管的至少一部分定位以过滤和控制流体流动的过滤器（108）。

3. 发明申请

WO2008033309A1 PFO CLIP 审中-公开
标题翻译： PFO剪辑
公开(公告)号：WO2008033309A1
公开(公告)日：2008-03-20
申请号：PCT/US2007/019677
申请日：2007-09-11
申请人： BOSTON SCIENTIFIC SCIMED, INC. , THIELEN, Joseph, M. , JENSON, Mark, L. , DRASLER, William, J.
发明人： THIELEN, Joseph, M. , JENSON, Mark, L. , DRASLER, William, J.
IPC分类号： A61B17/00
CPC分类号： A61B17/0057 , A61B17/083 , A61B2017/00575 , A61B2017/00592 , A61B2017/00606 , A61B2017/00867 , A61B2017/00893
摘要： Embodiments for a device, system and method for occluding an opening in a septum. Embodiments of the device can include a first control component, a first elongate member that extends from the first control component, a second elongate member, a connecting member that positions the first elongate member adjacent the second elongate member and a retraction member releasably coupled to the first control component. The retraction member can be used to change a relative position of the first elongate member and the second elongate member of the device.
摘要翻译：用于封闭隔膜中的开口的装置，系统和方法的实施例。该装置的实施例可以包括第一控制部件，从第一控制部件延伸的第一细长部件，第二细长部件，将第一细长部件定位成邻近第二细长部件的连接部件和可释放地联接到第一控制组件。缩回构件可用于改变第一细长构件和装置的第二细长构件的相对位置。

4. 发明申请

WO2008097967A2 SELF-ORIENTATING SUTURE WOUND CLOSURE DEVICE 审中-公开
标题翻译：自立式闭合闭合装置
公开(公告)号：WO2008097967A2
公开(公告)日：2008-08-14
申请号：PCT/US2008/053046
申请日：2008-02-05
申请人： BOSTON SCIENTIFIC SCIMED, INC. , DRASLER, William, J. , EIDENSCHINK, Tracee , THIELEN, Joeseph, M. , JENSON, Mark, L. , SADISIVA, Anu
发明人： DRASLER, William, J. , EIDENSCHINK, Tracee , THIELEN, Joeseph, M. , JENSON, Mark, L. , SADISIVA, Anu
IPC分类号： A61B17/00 , A61B17/34 , A61B19/00
CPC分类号： A61B17/0057 , A61B17/0469 , A61B2017/00641 , A61B2017/00663 , A61B2017/00867 , A61B2017/047 , A61B2017/0472 , A61B2017/3484 , A61B2090/067 , A61B2090/0811
摘要： A device is disclosed foi providing an indication as to the relative position of a vessel or aiteiy opening thereby facilitating the choice of which suturing or plugging technique to thereafter use. A disclosed device includes an outei tube and a collapsible foot slidably disposed within a distal end of the outei tube The foot is connected to a shaft that passes through the tube and exits a proximal end thereof The device may further include one or more threaded suture needles, a biodegradable plug or1 other wound closing device that is connected to another shaft The collapsed or1 folded foot is pushed distally out of the tube and through the opening in the vessel whereupon the foot expands Pulling the expanded foot in the proximal direction provides an indication as to the orientation of the opening in the vessel, which assists in determining the type of closing procedure to be carried out The shaft connected to the foot is preferably connected to an indicator that indicates to the operator or physician that the vessel opening is in one of three positions on the vessel - left, top or right As an alternative, the indicator bar may indicate a relative position in degrees, mm ot μm in deviation from a top stick (or1 top position)
摘要翻译：公开了一种提供关于容器的相对位置或有利开口的指示的装置，从而便于选择其后使用哪种缝合或堵塞技术。所公开的装置包括外壳管和可滑动地设置在外管的远端内的可折叠的脚。脚连接到穿过管并离开其近端的轴。该装置还可包括一个或多个螺纹缝合针，可生物降解的塞子或其他伤口闭合装置，其连接到另一个轴。折叠的或折叠的脚被向远侧推出管并通过容器中的开口，由此足部膨胀。沿近侧方向拉伸扩张的脚，提供指示有助于确定要执行的关闭程序的类型。连接到脚的轴优选地连接到指示器，该指示器向操作者或医师指示血管开口处于船上的三个位置 - 左侧，右侧或右侧。另外，指示杆可能表示相对位置，以mm为单位偏离顶杆（或顶部位置）

5. 发明申请

WO2008076895A1 STROKE INTERVENTION APPARATUS 审中-公开
公开(公告)号：WO2008076895A1
公开(公告)日：2008-06-26
申请号：PCT/US2007/087599
申请日：2007-12-14
申请人： BOSTON SCIENTIFIC SCIMED, INC. , JENSON, Mark, L. , DRASLER, William, J. , GILL, Jagjit
发明人： JENSON, Mark, L. , DRASLER, William, J. , GILL, Jagjit
IPC分类号： A61B5/03 , A61M27/00 , A61M25/00 , A61M25/10
CPC分类号： A61B5/03 , A61M25/003 , A61M25/0032 , A61M2025/0002 , A61M2025/1052
摘要： Disclosed herein is an intrathecal catheter (102) having a lumen (112) adapted to transfer liquid between the proximal end of the catheter and its distal end; a pressure detector (116); and a first sealer (120), adapted to seal the catheter against a tissue. Also disclosed herein is a stroke intervention system comprising an intrathecal catheter, an infusate supply chamber (206) in fluid communication with the catheter; a pump (204) in fluid communication with the catheter; and a pressure gauge in fluid cqmmunication with the pressure detector (116).
摘要翻译：本文公开了一种鞘内导管（102），其具有适于在导管的近端和其远端之间转移液体的内腔（112）压力检测器（116）; 以及适于将导管密封在组织上的第一密封件（120）。本文还公开了包括鞘内导管，与导管流体连通的输注供应室（206）的中风干预系统; 与所述导管流体连通的泵（204）; 以及压力计与压力检测器（116）的流体隔离。

6. 发明申请

WO2006031469A1 CARDIAC VALVE, SYSTEM, AND METHOD 审中-公开
标题翻译：心脏瓣膜，系统和方法
公开(公告)号：WO2006031469A1
公开(公告)日：2006-03-23
申请号：PCT/US2005/031329
申请日：2005-09-02
申请人： BOSTON SCIENTIFIC SCIMED, INC. , JENSON, Mark, L. , DRASLER, William, J. , LAFONTAINE, Daniel, M.
发明人： JENSON, Mark, L. , DRASLER, William, J. , LAFONTAINE, Daniel, M.
IPC分类号： A61F2/24
CPC分类号： A61F2/2418 , A61F2/2412 , A61F2230/008
摘要： A cardiac valve with a support frame having a first end member and a second end member opposing the first end member in a substantially fixed distance relationship, and a cover extending over the support frame to allow for unidirectional flow of a liquid through the valve.
摘要翻译：具有支撑框架的心脏瓣膜具有第一端构件和与所述第一端构件基本上固定的距离关系相对的第二端构件，以及在所述支撑框架上延伸以允许液体通过所述瓣膜的单向流动的盖。

7. 发明申请

WO2006011969A1 MYOCARDIAL TREATMENT APPARATUS AND METHOD OF TREATMENT 审中-公开
标题翻译：心肌治疗装置和治疗方法
公开(公告)号：WO2006011969A1
公开(公告)日：2006-02-02
申请号：PCT/US2005/020605
申请日：2005-06-10
申请人： BOSTON SCIENTIFIC SCIMED, INC. , JENSON, Mark, L. , DRASLER, William, J.
发明人： JENSON, Mark, L. , DRASLER, William, J.
IPC分类号： A61F2/06 , A61B17/11
CPC分类号： A61B17/320016 , A61B2017/00243 , A61F2/064 , A61F2/2493
摘要： Apparatus and methods for forming a conduit through an infarcted region where the conduit is in fluid communication with a supply of oxygenated blood and the venous vasculature and flowing oxygenated blood from the supply of oxygenated blood through the conduit and to the venous vasculature.
摘要翻译：用于通过梗塞区域形成导管的装置和方法，其中所述导管与氧合血液供应和所述静脉血管和来自所述供血的氧合血液通过所述导管和所述静脉血管的流动的氧合血液流体连通。

8. 发明申请

WO2011100547A2 AUTOMATIC VASCULAR CLOSURE DEPLOYMENT DEVICES AND METHODS 审中-公开
标题翻译：自动血管闭塞部署装置及方法
公开(公告)号：WO2011100547A2
公开(公告)日：2011-08-18
申请号：PCT/US2011/024527
申请日：2011-02-11
申请人： BOSTON SCIENTIFIC SCIMED, INC. , THIELEN, Joseph, M. , HILL, Jason, P. , JENSON, Mark, L. , PIKUS, Michael, J. , RICHARDSON, Leonard, B. , GROFF, Joel
发明人： THIELEN, Joseph, M. , HILL, Jason, P. , JENSON, Mark, L. , PIKUS, Michael, J. , RICHARDSON, Leonard, B. , GROFF, Joel
IPC分类号： A61B17/00 , A61B17/04 , A61B19/00
CPC分类号： A61B17/0057 , A61B17/0467 , A61B17/0487 , A61B2017/00654 , A61B2017/00663 , A61B2017/0417 , A61B2017/0496 , A61B2090/0807
摘要： Methods of installing a vascular closure device, the vascular closure device adapted for sealing an opening in biological tissue and comprising an anchor, a compressible plug, a cinch and a suture, the method comprising the steps of providing an insertion sheath, inserting the insertion sheath into the opening in the biological tissue, providing a device sheath having the vascular closure device preloaded therein with a proximal portion of the suture attached to the device sheath, subsequent to the step of inserting the insertion sheath, inserting the device sheath into the insertion sheath, and retracting the insertion sheath and device sheath simultaneously, wherein during the retraction, the insertion sheath and the device sheath are fixed to one another and devices adapted to the methods.
摘要翻译：一种安装血管闭合装置的方法，所述血管闭合装置适用于密封生物组织中的开口并且包括锚固件，可压缩塞子，束带和缝合线，所述方法包括以下步骤：提供插入鞘，插入所述插入鞘进入生物组织中的开口，提供装置护套，其中预先装载有血管闭合装置的血管闭合装置具有附接到装置护套的缝合线的近侧部分，在插入插入鞘的步骤之后，将装置护套插入插入鞘中并且同时缩回插入鞘和装置护套，其中在缩回期间，插入鞘和装置护套彼此固定并适应于该方法的装置。

9. 发明申请

WO2008121632A2 EMBOLIC CAPTURING DEVICES AND METHODS 审中-公开
标题翻译：嵌入式捕获装置和方法
公开(公告)号：WO2008121632A2
公开(公告)日：2008-10-09
申请号：PCT/US2008/058177
申请日：2008-03-26
申请人： BOSTON SCIENTIFIC SCIMED, INC. , JENSON, Mark, L. , DRASLER, William, J.
发明人： JENSON, Mark, L. , DRASLER, William, J.
IPC分类号： A61B17/22
CPC分类号： A61B17/221 , A61B2017/22082 , A61B2017/2212 , A61B2017/2946 , A61B2090/0811
摘要： Disclosed is an emboli capturing device having a first support hoop at a distal portion of a first elongate member, and a support member that is coupled to the first support hoop. The support member can comprise a second elongate member. In some cases, the second elongate member can be coupled to the first support hoop. In other cases, the support member can comprise a second elongate member and a support strut. The support strut can be coupled to both the first support hoop and the second elongate member. Movement of the support member relative to the first elongate member can translate the first support hoop between collapsed and expanded configurations. Once in a desired configuration, the support members can also provide support to maintain the first support hoop in the desired configuration. Also disclosed is a combination emboli capturing and perfusion device. The combination device can have a perfusion member in combination with an emboli capturing device. The perfusion member can facilitate the introduction of fluids around a lesion in a vessel of a patient, for example if the lesion is creating a partial or total occlusion of the vessel.
摘要翻译：公开了一种栓塞捕获装置，其在第一细长构件的远端部分具有第一支撑环，以及联接到第一支撑环的支撑构件。支撑构件可以包括第二细长构件。在一些情况下，第二细长构件可以联接到第一支撑环。在其他情况下，支撑构件可以包括第二细长构件和支撑支柱。支撑支柱可以联接到第一支撑环和第二细长构件。支撑构件相对于第一细长构件的运动可以在折叠和膨胀构型之间平移第一支撑箍。一旦处于期望的构造，支撑构件还可以提供支撑以将第一支撑环保持在期望的构造。还公开了组合栓塞和灌注装置。组合装置可以具有与栓塞捕获装置组合的灌注构件。灌注构件可以促进在患者的血管中的病变周围引入流体，例如，如果病变产生血管的部分或完全闭塞。

10. 发明申请

WO2008097956A1 VASCULAR SEALING DEVICE AND METHOD USING CLOT ENHANCING BALLOON AND ELECTRIC FIELD GENERATION 审中-公开
标题翻译：油封密封装置和使用加强气球和电场产生的方法
公开(公告)号：WO2008097956A1
公开(公告)日：2008-08-14
申请号：PCT/US2008/053034
申请日：2008-02-05
申请人： BOSTON SCIENTIFIC SCIMED, INC. , DRASLER, William, J. , EIDENSCHINK, Tracee , THIELEN, Joeseph, M. , JENSON, Mark, L. , SADISIVA, Anu
发明人： DRASLER, William, J. , EIDENSCHINK, Tracee , THIELEN, Joeseph, M. , JENSON, Mark, L. , SADISIVA, Anu
IPC分类号： A61B17/00 , A61B18/00
CPC分类号： A61B18/14 , A61B17/0057 , A61B2017/00654 , A61N1/18 , A61N1/32
摘要： An apparatus and method for closing an opening in a blood vessel wall is disclosed. The apparatus includes at least one member which is extended through a tissue tract formed though the epidermis and subcutaneous layer of skin and through the opening in the blood vessel. The member includes a proximal end and a distal end with the distal end being positionable proximate to the opening in the blood vessel wall. A positive electrode is positioned next to the distal end with a negative electrode being positioned next to the proximal end When the electrodes are energized an electric field is created therebetween, blood cells are attracted to the positive electrode, and a thrombus is formed at the opening in the blood vessel wall. The member may include a balloon at the distal end to temporarily occlude blood flow from the blood vessel to the tissue tract to facilitate formation of the thrombus. In addition, the shape of the balloon may be tailored to facilitate the formation of the thrombus including, but not limited to, the creation of pockets and self-supporting balloons.
摘要翻译：公开了一种用于封闭血管壁中的开口的装置和方法。该装置包括至少一个构件，其延伸穿过通过皮肤的表皮和皮下层形成并通过血管中的开口形成的组织通道。该构件包括近端和远端，远端可靠近血管壁中的开口定位。正电极位于远端附近，负极位于近端的旁边。当电极通电时，电极之间产生电场，血细胞被吸引到正电极，并且在开口处形成血栓在血管壁。该构件可以包括在远端处的气囊，以暂时阻断从血管到组织道的血流，以促进血栓的形成。此外，气囊的形状可以被调整以促进血栓的形成，包括但不限于口袋和自支撑气囊的产生。

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