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1. 发明申请

WO2006074002A1 METHOD FOR MAKING EPTFE AND STRUCTURE CONTAINING SUCH EPTFE, SUCH AS A VASCULAR GRAFT 审中-公开
标题翻译：用于制造EPTFE和包含这种EPTFE的结构的方法，例如血管片
公开(公告)号：WO2006074002A1
公开(公告)日：2006-07-13
申请号：PCT/US2005/047253
申请日：2005-12-29
申请人： BOSTON SCIENTIFIC SCIMED, INC. , DURAN, Julio , SOWINSKI, Krzysztof
发明人： DURAN, Julio , SOWINSKI, Krzysztof
IPC分类号： A61L27/16 , B29C55/26 , A61F2/06
CPC分类号： A61L27/16 , A61F2/07 , A61F2002/075 , B29C55/26 , B29K2027/18 , B29L2031/7534 , Y10T428/1352 , Y10T428/139 , C08L27/18
摘要： A method for making a vascular graft includes providing a PTFE green tube extrudate (12) which is un-sintered, and then initially expanding the un-sintered extrudate (17) to produce an initial node and fibril micro-structure therein. This is followed by heating the extrudate to raise the temperature thereof for a time period of sufficient duration such that the extrudate is partially sintered. The partially sintered extrudate is subsequently expanded (25) to make the vascular graft. The subsequent expansion produces a subsequent node and fibril microstructure in the vascular graft. An alternative method for making a vascular graft includes providing a PTFE green tube extrudate which is un-sintered, longitudinally expanding the unsintered extrudate to form an ePTFE tube structure, and radially expanding the un-sintered ePTFE tube structure. ePTFE made according to the method is fabricated into various structures, such as tube structures, filament structures, and sheet structures.
摘要翻译：制造血管移植物的方法包括提供未烧结的PTFE绿色管挤出物（12），然后最初膨胀未烧结的挤出物（17）以在其中产生初始节点和原纤维微结构。然后加热挤出物以使其温度持续足够的时间以使挤出物部分烧结。随后将部分烧结的挤出物膨胀（25）以制备血管移植物。随后的扩张在血管移植物中产生后续的节点和原纤维微结构。制备血管移植物的替代方法包括提供未烧结的PTFE绿色管挤出物，纵向膨胀未烧结的挤出物以形成ePTFE管结构，以及径向膨胀未烧结的ePTFE管结构。根据该方法制成的ePTFE被制成各种结构，例如管结构，细丝结构和片状结构。

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