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1. 发明申请

WO2007094934A1 RADIO FREQUENCY INDUCED DRUG ELUTION 审中-公开
标题翻译：无线电频率诱导药物
公开(公告)号：WO2007094934A1
公开(公告)日：2007-08-23
申请号：PCT/US2007/001903
申请日：2007-01-25
申请人： BOSTON SCIENTIFIC SCIMED, INC. , BEHAN, Niall , MALONE, Anthony , FLANAGAN, Alden , O'BRIEN, Barry , MOTHERWELL, John , MCMORROW, David
发明人： BEHAN, Niall , MALONE, Anthony , FLANAGAN, Alden , O'BRIEN, Barry , MOTHERWELL, John , MCMORROW, David
IPC分类号： A61F2/88 , A61K9/00
CPC分类号： A61F2/88 , A61F2210/009 , A61F2250/0001 , A61F2250/0035 , A61F2250/0068 , A61L31/14 , A61L31/16 , A61L2300/608 , A61M31/002 , A61N2/002
摘要： A medical device including at least one reservoir, adapted to contain a material, such as a therapeutic agent, and sealed by a cover. The reservoir is openable, so as to release the material, for example, by (i) disintegration of the cover, (ii) movement of the cover to an open position, and/or (iii) a change of composition or properties of the cover allowing the material to pass therethrough. The power required to open the reservoir is provided by a current induced in a coil associated with the medical device by a change in magnetic flux in the area of the medical device.
摘要翻译：一种包括至少一个储存器的医疗装置，其适于容纳诸如治疗剂的材料，并被盖子密封。储存器是可打开的，以便释放材料，例如通过（i）盖子的分解，（ii）盖子移动到打开位置，和/或（iii）改变构件的组成或特性盖子允许材料通过。通过在医疗装置的区域中的磁通量的变化，通过在与医疗装置相关联的线圈中感应的电流来提供打开储存器所需的功率。

2. 发明申请

WO2006096287A1 COATING A MEDICAL APPLIANCE UTILIZING A VIBRATING MESH NEBULIZER 审中-公开
标题翻译：涂覆一个医疗器具使用振动网格NEBULIZER
公开(公告)号：WO2006096287A1
公开(公告)日：2006-09-14
申请号：PCT/US2006/004994
申请日：2006-02-14
申请人： BOSTON SCIENTIFIC SCIMED, INC. , BEHAN, Niall , MCMORROW, David , O'CONNOR, Timothy
发明人： BEHAN, Niall , MCMORROW, David , O'CONNOR, Timothy
IPC分类号： B05B17/06
CPC分类号： B05B17/0646 , A61L2420/02 , B05D1/02
摘要： A method of coating a medical appliance is provided that includes contacting a coating material (131) with a first side of a mesh nebulizer (110) . The mesh nebulizer (110) includes at least one aperture. The method also includes vibrating the mesh nebulizer (110) and arranging the medical appliance (100) in a region of a second side of the mesh nebulizer (110) . The second side is opposite the first side. A system is provided for coating a medical appliance (100) that includes a coating source (130) , a mesh nebulizer (110) an arrangement (120,121) for vibrating the mesh nebulizer (110) , and an arrangement for holding the medical appliance (100) .
摘要翻译：提供了一种涂覆医疗器具的方法，包括使涂层材料（131）与网状喷雾器（110）的第一侧接触。网状雾化器（110）包括至少一个孔。该方法还包括使网状雾化器（110）振动并将医疗器具（100）布置在网状喷雾器（110）的第二侧的区域中。第二面与第一面相对。提供一种用于涂覆医疗器具（100）的系统，其包括涂料源（130），网眼雾化器（110），用于振动网眼雾化器（110）的装置（120,121），以及用于保持医疗器具 100）。

3. 发明申请

WO2007126769A2 METHOD OF MAKING A COATED MEDICAL DEVICE 审中-公开
标题翻译：制造涂层医疗器械的方法
公开(公告)号：WO2007126769A2
公开(公告)日：2007-11-08
申请号：PCT/US2007/007494
申请日：2007-03-26
申请人： BOSTON SCIENTIFIC SCIMED, INC. , CLARKE, John , BEHAN, Niall , MALONE, Anthony
发明人： CLARKE, John , BEHAN, Niall , MALONE, Anthony
CPC分类号： B05D5/00 , A61L31/10 , A61L31/146 , A61L31/16 , A61L2300/416 , A61L2420/02 , B05D3/007
摘要： The present invention relates to a method of making a coated medical device with a porous coating. The method includes coating at least a portion of the surface of a medical device with a coating composition comprising a polymer, solvent, and a gas, and then removing an amount of gas from the coating composition sufficient to form a porous coating. A biologically active material can be included in the coating composition.
摘要翻译：本发明涉及一种制备具有多孔涂层的涂覆医疗装置的方法。该方法包括用包含聚合物，溶剂和气体的涂料组合物涂覆医疗器械表面的至少一部分，然后从足以形成多孔涂层的涂料组合物中除去一定量的气体。生物活性物质可以包括在涂料组合物中。

4. 发明申请

WO2011073968A1 A DRUG DELIVERY SYSTEM 审中-公开
标题翻译：药物递送系统
公开(公告)号：WO2011073968A1
公开(公告)日：2011-06-23
申请号：PCT/IE2010/000074
申请日：2010-12-17
申请人： VYSERA BIOMEDICAL LIMITED , BEHAN, Niall
发明人： BEHAN, Niall
IPC分类号： A61L31/10 , A61L31/14 , A61L31/16
CPC分类号： A61L31/10 , A61L31/146 , A61L31/16 , A61L2300/00
摘要： A drug delivery medical device such as a gastrointestinal stent comprises a support (1) which has an outer cover or coating (2). The cover or coating comprises a plurality of patches or tiles (3) of a polymeric material which contain a drug. The patches (3) form a continuous or discontinuous mosaic. The patches may be held together using a biodegradable adhesive.
摘要翻译：诸如胃肠支架的药物递送医疗装置包括具有外覆盖物或涂层（2）的支撑件（1）。覆盖物或涂层包含多个包含药物的聚合物材料的贴剂或瓷砖（3）。贴片（3）形成连续或不连续的马赛克。可以使用可生物降解的粘合剂将贴剂保持在一起。

5. 发明申请

WO2011073967A1 A BIOMATERIAL 审中-公开
标题翻译：生物材料
公开(公告)号：WO2011073967A1
公开(公告)日：2011-06-23
申请号：PCT/IE2010/000073
申请日：2010-12-17
申请人： VYSERA BIOMEDICAL LIMITED , BEHAN, Niall
发明人： BEHAN, Niall
IPC分类号： C08G77/42 , C08G77/458 , C08G18/61 , C08G18/69 , A61L27/18 , A61L29/06 , A61F2/24
CPC分类号： C08G77/42 , A61F2/24 , A61L27/18 , A61L27/34 , A61L29/06 , A61L29/085 , C08G18/10 , C08G18/61 , C08G18/69 , C08G77/458 , C08G2101/0008 , C08L75/04 , C08L83/04 , C08G18/50
摘要： The present invention provides a triblock copolymer and a viscoelastic biostable foam comprising the same.
摘要翻译：本发明提供三嵌段共聚物和包含该三嵌段共聚物的粘弹性生物稳定性泡沫体。

6. 发明申请

WO2009153769A1 A BIOMATERIAL 审中-公开
标题翻译：生物材料
公开(公告)号：WO2009153769A1
公开(公告)日：2009-12-23
申请号：PCT/IE2009/000038
申请日：2009-06-19
申请人： VYSERA BIOMEDICAL LIMITED , BEHAN, Niall , KUMAR, Ashutosh
发明人： BEHAN, Niall , KUMAR, Ashutosh
IPC分类号： A61F2/24 , C08G77/388 , C08G77/458 , C08L83/10 , C08G18/61
CPC分类号： A61F2/04 , A61F2002/044 , A61F2002/045 , A61F2230/0069 , A61L27/18 , A61L27/56 , A61M39/22 , C08G18/5096 , C08G18/61 , C08G18/6535 , C08G77/388 , C08G77/445 , C08G77/448 , C08G77/458 , C08G77/46 , C08G2101/0008 , C08G2101/0083 , C08L83/10
摘要： The present invention provides a triblock copolymer and a viscoelastic biostable foam comprising the same.
摘要翻译：本发明提供三嵌段共聚物和包含该三嵌段共聚物的粘弹性生物稳定性泡沫体。

7. 发明申请

WO2012080997A1 A GASTROINTESTINAL IMPLANT DEVICE 审中-公开
标题翻译： GASTROINTESTINAL植物装置
公开(公告)号：WO2012080997A1
公开(公告)日：2012-06-21
申请号：PCT/IE2011/000067
申请日：2011-12-19
申请人： VYSERA BIOMEDICAL LIMITED , BEHAN, Niall
发明人： BEHAN, Niall
IPC分类号： A61F5/00
CPC分类号： A61F5/0079
摘要： A gastrointestinal implant device (600) comprises a sleeve (601) for extending into the duodenum and an artificial valve (602) for placement at the pylorus (603) to control flow from the stomach into the duodenal sleeve. A support structure for the valve comprises a scaffold (605) to which the valve is mounted and a luminal prosthesis. The luminal prosthesis (606) comprises a proximal flare (620) for location at the antrum of the pylorus, a bulbous region (621), and a scaffold receiving region (622).
摘要翻译：消化道植入装置（600）包括用于延伸到十二指肠的套筒（601）和用于放置在幽门（603）处以控制从胃进入十二指肠套管的流动的人造瓣膜（602）。用于阀的支撑结构包括安装阀的支架（605）和管腔假体。管腔假体（606）包括用于位于幽门窦处的近端扩张（620），球茎区域（621）和脚手架接收区域（622）。

8. 发明申请

WO2012059906A1 A UROLOGICAL DEVICE 审中-公开
标题翻译：泌尿器官
公开(公告)号：WO2012059906A1
公开(公告)日：2012-05-10
申请号：PCT/IE2011/000060
申请日：2011-11-03
申请人： VYSERA BIOMEDICAL LIMITED , BEHAN, Niall
发明人： BEHAN, Niall
IPC分类号： A61M25/00 , A61M39/24 , A61F2/00 , A61F2/04
CPC分类号： A61F2/0022 , A61F2/0009 , A61F2/042 , A61M25/0017 , A61M25/0075 , A61M39/06 , A61M39/0606 , A61M39/24 , A61M2039/0633 , A61M2039/0646 , A61M2039/242 , A61M2039/2426 , A61M2039/2433
摘要： A urological device (800, 810, 830, 850, 860, 870, 900, 910, 920) comprises a urological valve (802, 803, 812, 861, 901), for location in the bladder of a patient and a valve support stem (801, 813, 863, 902), for location in the urethra of a patient. The valve has a normally closed configuration to prevent flow from the bladder and an open configuration for fluid flow through the valve. The valve is automatically movable from the closed configuration to the open configuration in response to a pre -set hydrodynamic pressure applied for a pre-set time. In one case the valve has a plurality of valve leaflets with a region of co-aption between the valve leaflets. In the normally closed configuration the valve leaflets are engaged at the region of co-aption and in the open configuration the leaflets are separated at the co-aption region for fluid flow through the valve.
摘要翻译：尿液装置（800,810,830,850,860,870,900,910,920）包括尿布阀（802,803,812,861,901），用于位于患者的膀胱中，并且阀支撑件茎（801,813,863,902），用于位于患者的尿道中。该阀具有常闭结构，以防止从气囊流出，并且液体流过阀的打开构型。响应于施加预设时间的预设流体动力压力，阀可以从关闭构型自动移动到打开构型。在一种情况下，阀具有多个瓣叶，其瓣与瓣膜之间具有相互配合的区域。在常闭构型中，瓣叶在共同的区域接合，并且在开放构型中，叶片在共同部分处被分离，用于通过阀的流体流动。

9. 发明申请

WO2009153770A1 ESOPHAGEAL VALVE 审中-公开
标题翻译：食管阀
公开(公告)号：WO2009153770A1
公开(公告)日：2009-12-23
申请号：PCT/IE2009/000039
申请日：2009-06-19
申请人： VYSERA BIOMEDICAL LIMITED , SOBRINO-SERRANO, Gabriel , BEHAN, Niall , O'HALLORAN, Anthony
发明人： SOBRINO-SERRANO, Gabriel , BEHAN, Niall , O'HALLORAN, Anthony
IPC分类号： A61F2/24
CPC分类号： A61F2/04 , A61F2/2412 , A61F2/2418 , A61F2002/044 , A61F2002/045
摘要： A valve such as an esophageal valve (1) has a normally closed configuration in which the valve (1) is closed and an open configuration in which the valve (1) is opened for flow through the valve (1). A support (102) for the valve (1) is adapted for mounting to a pre-deployed luminal prosthesis (140) intermediate a proximal end and a distal end of the predeployed luminal prosthesis (140).
摘要翻译：诸如食管阀（1）的阀具有常闭形式，阀（1）关闭，阀（1）打开以打开以流过阀（1）的打开构造。用于阀（1）的支撑件（102）适于安装到预部署腔内假体（140）的近端和远端之间的预先布置的腔内假体（140）。

10. 发明申请

WO2009153768A1 ESOPHAGEAL VALVE 审中-公开
标题翻译：食管阀
公开(公告)号：WO2009153768A1
公开(公告)日：2009-12-23
申请号：PCT/IE2009/000037
申请日：2009-06-19
申请人： VYSΕRA BIOMEDICAL LIMITED , SOBRINO - SERRANO, Gabriel , BEHAN, Niall , O'HALLORAN, Anthony
发明人： SOBRINO - SERRANO, Gabriel , BEHAN, Niall , O'HALLORAN, Anthony
IPC分类号： A61F2/24
CPC分类号： A61F2/04 , A61F2/2412 , A61F2/2418 , A61F2002/044 , A61F2002/045
摘要： An esophageal valve (1) comprising a polymeric valve body having an outer support region (2) at least three valve leaflets (3, 4, 5), and a main body region (6) extending between the support region (2) and the valve leaflets (3, 4, 5). The valve (1) has a normally closed configuration in which the valve (1) is closed, an antegrade open configuration in which the valve leaflets (3, 4, 5) are opened in response to an antegrade force to allow flow through the valve (1), and a retrograde open configuration in response to a retrograde force which is substantially larger than the antegrade force.
摘要翻译： 1.一种食管阀（1），包括具有外支撑区域（2）的至少三个瓣叶（3,4,5）的主体区域（6）的聚合物阀体，以及在所述支撑区域（2）和所述支撑区域瓣叶（3,4,5）。阀（1）具有常闭构造，其中阀（1）关闭，顺向打开构造，其中阀叶（3,4,5）响应于顺流力而打开以允许流过阀（1），以及响应于基本上大于顺行力的逆行力的逆行打开构造。

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