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1. 发明申请

WO2014043694A1 COLLARLESS GUIDE EXTENSION CATHETER 审中-公开
标题翻译：无缝导纱器
公开(公告)号：WO2014043694A1
公开(公告)日：2014-03-20
申请号：PCT/US2013/060151
申请日：2013-09-17
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： ZHOU, Pu , GULER, Ismail
IPC分类号： A61M25/00 , A61M25/04
CPC分类号： A61M25/01 , A61M25/0012 , A61M25/0052 , A61M25/0053 , A61M25/0069 , A61M25/04 , Y10T29/49826
摘要： Embodiments of the disclosure describe an example guide extension catheter (100). The guide extension catheter includes a proximal shaft (102) having a proximal end (104), a distal end (106), the distal end having an attachment region (108). The guide extension catheter may further include a distal sheath (110) having a proximal end (114), a distal end (112) and a lumen extending therebetween. The distal sheath may include an outer layer (120), inner layer (119) and an intermediate reinforcing member (116) disposed between the inner layer and the outer layer. Moreover, the distal sheath is attached to the attachment region adjacent to the reinforcing member.
摘要翻译：本公开的实施例描述了示例性引导延伸导管（100）。引导延伸导管包括具有近端（104）的近端轴（102），远端（106），远端具有附接区域（108）。引导延伸导管还可以包括具有近端（114），远端（112）和在其间延伸的内腔的远侧护套（110）。远侧鞘可以包括设置在内层和外层之间的外层（120），内层（119）和中间加强构件（116）。此外，远侧护套附接到与加强构件相邻的附接区域。

2. 发明申请

WO2008002586A2 COATINGS FOR MEDICAL DEVICES COMPRISING A THERAPEUTIC AGENT AND A METALLIC MATERIAL 审中-公开
标题翻译：包含治疗剂和金属材料的医疗装置用涂层
公开(公告)号：WO2008002586A2
公开(公告)日：2008-01-03
申请号：PCT/US2007/014851
申请日：2007-06-25
申请人： BOSTON SCIENTIFIC SCIMED, INC. , ZHOU, Pu
发明人： ZHOU, Pu
IPC分类号： A61F2/82
CPC分类号： A61L31/16 , A61F2/82 , A61F2002/30322 , A61F2250/0026 , A61F2250/0067 , A61L31/082 , A61L31/10 , A61L2300/416 , A61L2300/608 , A61L2420/08
摘要： The invention relates generally to an implantable medical device for delivering a therapeutic agent to the body tissue of a patient, and a method for making such a medical device. In particular, the invention pertains to an implantable medical device, such as an intravascular stent, having a coating comprising a first coating composition comprising a therapeutic agent and, optionally, a polymer; and a second coating composition comprising a metallic material.
摘要翻译：本发明一般涉及用于将治疗剂递送至患者身体组织的可植入医疗装置，以及制造这种医疗装置的方法。具体而言，本发明涉及具有涂层的可植入医疗装置，例如血管内支架，所述涂层包含第一涂层组合物和第二涂层组合物，所述第一涂层组合物包含治疗剂和任选的聚合物; 和包含金属材料的第二涂料组合物。

3. 发明申请

WO2014113378A1 SUBINTIMAL RE-ENTRY CATHETER WITH ACTUATABLE ORIENTATION MECHANISM 审中-公开
标题翻译：具有可执行定向机构的次级再入口导管
公开(公告)号：WO2014113378A1
公开(公告)日：2014-07-24
申请号：PCT/US2014/011458
申请日：2014-01-14
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： ZHOU, Pu , WANG, Huisun
IPC分类号： A61B17/3207
CPC分类号： A61B17/22 , A61B17/3207 , A61B17/3478 , A61B2017/22044 , A61B2017/22095 , A61B2090/3966 , A61M25/0071 , A61M25/0074 , A61M25/0108 , A61M25/0169
摘要： A recanalization catheter for facilitating re-entry into a lumen of a blood vessel from a subintimal space. The recanalization catheter includes first and second mechanically actuatable wings positioned at a distal region of the elongate shaft of the catheter that are actuatable between a retracted position and an expanded position. In the retracted position the mechanically actuatable wings are positioned in first and second elongate channels defined in the elongate shaft, and in the expanded position the mechanically actuatable wings extend outward from the first and second elongate channels. The actuatable wings extend in an arcuate path away from the elongate shaft in the expanded position to be positionable in a circumferential orientation within a subintimal space formed in a vessel wall to automatically orient a lateral port of the elongate shaft toward the true lumen.
摘要翻译：再通管道，用于促进从内膜空间重新进入血管腔。再通导管包括位于导管的细长轴的远侧区域处的第一和第二机械致动翼，其可在缩回位置和扩张位置之间致动。在缩回位置，机械致动的翼定位在限定在细长轴中的第一和第二细长通道中，并且在扩展位置中，机械致动翼从第一和第二细长通道向外延伸。可致动的翼片在弓形路径中在扩展位置上远离细长轴延伸，以便在形成于血管壁中的内膜下空间内以圆周方向定位，以便使细长轴的侧向端口朝向真腔流动。

4. 发明申请

WO2009143160A1 MEDICAL DEVICE INCLUDING A BRAID FOR CROSSING AN OCCLUSION IN A VESSEL 审中-公开
标题翻译：医疗装置，包括用于横穿血管内的血管的BRAID
公开(公告)号：WO2009143160A1
公开(公告)日：2009-11-26
申请号：PCT/US2009/044529
申请日：2009-05-19
申请人： BOSTON SCIENTIFIC SCIMED, INC. , CHEN, Hancun , ZHOU, Pu
发明人： CHEN, Hancun , ZHOU, Pu
IPC分类号： A61M25/09
CPC分类号： A61M25/09033 , A61M2025/09075 , A61M2025/09108 , A61M2025/09133 , A61M2025/09175
摘要： The application provides design, material, manufacturing method, and use alternatives for medical devices. An example medical guidewire (10) includes an elongate core member (20) including a proximal region (14) and a distal region (12), a braid member (18) disposed about at least a portion of the distal region of the elongate core member, a polymer member (24) disposed between at least a portion of the elongate core member and the braid member, and a polymer sleeve member (16) disposed about at least a portion of the braid member. The proximal region of the core member is free of the braid member.
摘要翻译：该应用程序提供医疗设备的设计，材料，制造方法和使用替代品。示例性医疗导线（10）包括细长的芯构件（20），其包括近侧区域（14）和远侧区域（12），编织构件（18）围绕细长芯的远侧区域的至少一部分构件，设置在细长芯构件和编织构件的至少一部分之间的聚合物构件（24）和围绕编织构件的至少一部分设置的聚合物套筒构件（16）。芯构件的近侧区域没有编织构件。

5. 发明申请

WO2014036163A1 RENAL RF ABLATION SYSTEM WITH A MOVABLE VIRTUAL ELECTRODE AND RELATED METHODS OF USE 审中-公开
标题翻译：具有可移动虚拟电极的RENAL RF ABLATION系统及其相关使用方法
公开(公告)号：WO2014036163A1
公开(公告)日：2014-03-06
申请号：PCT/US2013/057124
申请日：2013-08-28
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： ZHOU, Pu , WANG, Huisun , CAO, Hong
IPC分类号： A61B18/14 , A61B17/00 , A61M25/00 , A61M25/01 , A61B18/00 , A61M25/02
CPC分类号： A61B18/18 , A61B18/1492 , A61B2017/00305 , A61B2017/00469 , A61B2018/00279
摘要： Tissue ablation devices and methods for using tissue ablation devices are disclosed. A tissue ablation device may include an elongate guide member having a distal section defined by a sidewall defining a lumen and having a plurality of openings. The distal section may have a helical shape in a released configuration. The tissue ablation device also may include an electrode having a distal end slideable within the distal section of the guide member. The electrode catheter may have an ablation element disposed thereon.
摘要翻译：公开了组织消融装置和使用组织消融装置的方法。组织消融装置可以包括细长引导构件，其具有由侧壁限定的远侧部分，所述侧壁限定内腔并具有多个开口。远端部分可以具有处于释放构型的螺旋形状。组织消融装置还可以包括具有可在引导构件的远侧部分内滑动的远端的电极。电极导管可以具有设置在其上的消融元件。

6. 发明申请

WO2014011888A1 LOW PROFILE HEART VALVE DELIVERY SYSTEM AND METHOD 审中-公开
标题翻译：低剖面心瓣输送系统及方法
公开(公告)号：WO2014011888A1
公开(公告)日：2014-01-16
申请号：PCT/US2013/050087
申请日：2013-07-11
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： ZHOU, Pu , WANG, Huisun , FENG, James Q.
IPC分类号： A61F2/966 , A61F2/24
CPC分类号： A61F2/2436 , A61F2/2418 , A61F2/2427 , A61F2/966 , A61F2210/0004 , A61F2220/0075
摘要： A heart valve delivery system includes a low-profile catheter having an outer sheath, the outer sheath having therein a stent and a replacement heart valve. In an unemployed configuration, the stent is located distally to the replacement heart valve. Upon deployment, however, the stent and replacement heart valve are expanded and the replacement heart valve is situated within the stent.
摘要翻译：心脏瓣膜输送系统包括具有外护套的低轮廓导管，外护套在其中具有支架和置换心脏瓣膜。在失业的配置中，支架位于替换心脏瓣膜的远端。然而，部署后，支架和置换心脏瓣膜扩张，置换心脏瓣膜位于支架内。

7. 发明申请

WO2014011330A1 COLLAPSIBLE CAGED-BALL PROSTHETIC VALVE FOR TRANSCATHETER DELIVERY AND METHOD OF USE 审中-公开
标题翻译：用于交通运输的可拆卸的CAGED-BALL PROSTHE VALVE VALTION和使用方法
公开(公告)号：WO2014011330A1
公开(公告)日：2014-01-16
申请号：PCT/US2013/044057
申请日：2013-06-04
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： WANG, Huisun , ZHOU, Pu
IPC分类号： A61F2/24
CPC分类号： A61F2/06 , A61F2/2409 , A61F2/2424 , A61F2/2436 , A61F2250/0003
摘要： A valve (10) that includes an expandable valve body (22) defining a lumen and a longitudinally moveable obstructer (40) retained within the lumen of the valve body between the proximal and distal ends of the valve when the valve is in an expanded configuration. The valve, in the collapsed configuration, is delivered to a native valve site by a catheter where the valve body is expanded to anchor the valve at the valve annulus and the collapsed obstructer is subsequently expanded so that the valve is in the expanded configuration.
摘要翻译：一种阀（10），其包括限定内腔的可膨胀阀体（22）和当所述阀处于膨胀构型时在所述阀的近端和远端之间保持在所述阀体的内腔内的纵向移动阻塞件（40）。处于收缩状态的阀通过导管被输送到天然瓣膜部位，其中阀体被膨胀以将瓣膜锚定在瓣膜环上，并且收缩的阻塞器随后被扩张，使得瓣膜处于扩张构型。

8. 发明申请

WO2011115882A1 DRUG ELUTING STENTS AND METHODS OF MAKING THE SAME 审中-公开
标题翻译：药物治疗方法及其制备方法
公开(公告)号：WO2011115882A1
公开(公告)日：2011-09-22
申请号：PCT/US2011/028298
申请日：2011-03-14
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： ZHOU, Pu , FENG, James , ARCAND, Benjamin , SHIPPY, James Lee
IPC分类号： A61L31/04 , A61L31/06 , A61L31/14 , A61L31/16 , A61F2/82
CPC分类号： A61F2/82 , A61F2240/001 , A61F2250/0067 , A61L31/04 , A61L31/06 , A61L31/148 , A61L31/16 , C08L67/04
摘要： A stent formed from a bioabsorbable polymer matrix including at least one bioabsorbable polymer and at least one therapeutic agent dispersed therein, and methods of making the same.
摘要翻译：由包含至少一种生物可吸收聚合物和分散在其中的至少一种治疗剂的生物可吸收聚合物基质形成的支架及其制备方法。

9. 发明申请

WO2008045156A1 STENT PROTECTOR DESIGN 审中-公开
标题翻译： STENT保护器设计
公开(公告)号：WO2008045156A1
公开(公告)日：2008-04-17
申请号：PCT/US2007/017994
申请日：2007-08-14
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： WASDYKE, Joel , JOHNSON, Michael D. , SORENSON, Shawn , ADNEY, Raymond , PERIAKARUPPAN, Ram , HEIDNER, Matt , MCNULTY, Sean , ZHOU, Pu
IPC分类号： A61F2/84
CPC分类号： A61F2/0095 , A61F2/95 , A61F2/958 , A61F2002/9522 , A61M25/002
摘要： A catheter assembly (10) comprises a catheter (30) having a distal end and a longitudinal axis, a stent (20) disposed about the distal end of the catheter, and a stent protector (40). The stent protector has a stent covering portion (44) disposed about the stent and a catheter engagement portion (42) that removably engages the stent protector to the catheter assembly. The stent covering portion is disposed about the stent without substantially engaging the stent.
摘要翻译：导管组件（10）包括具有远端和纵向轴线的导管（30），围绕导管的远端设置的支架（20）和支架保护器（40）。支架保护器具有围绕支架设置的支架覆盖部分（44）和导管接合部分（42），其将支架保护器可拆卸地接合到导管组件。支架覆盖部分围绕支架设置，而基本上不接合支架。

10. 发明申请

WO2014124283A1 EXPANDABLE SHEATH 审中-公开
标题翻译：可膨胀的沙子
公开(公告)号：WO2014124283A1
公开(公告)日：2014-08-14
申请号：PCT/US2014/015341
申请日：2014-02-07
申请人： BOSTON SCIENTIFIC SCIMED, INC.
发明人： ZHOU, Pu , WANG, Huisun
IPC分类号： A61M25/06 , A61M25/00 , A61M39/06
CPC分类号： A61M25/09 , A61M25/0043 , A61M25/0045 , A61M25/005 , A61M25/0071 , A61M25/0074 , A61M25/0662 , A61M39/06 , A61M2025/0024
摘要： A medical device assembly may include an elongated tubular membrane (20, 320, 420) having a wall (422) defining a lumen extending through the membrane from a proximal end to a distal end, the lumen having a first inner diameter, and a percutaneous medical device having a maximum outer diameter greater than the first inner diameter, wherein the membrane is configured to permit the medical device to pass through the lumen, and wherein the membrane includes a plurality of longitudinally-oriented channels (450) recessed along an inner surface of the wall. A medical device delivery sheath may include a tubular first layer (222) of polymeric material formed into a wavy cross-section having a plurality of lobes (230) and a plurality of valleys (240), wherein the first layer of material is resiliently expandable in a radial direction from a relaxed configuration to an expanded configuration, and wherein the first layer of material is substantially non-expandable in an axial direction.
摘要翻译：医疗器械组件可以包括细长管状膜（20,320,420），其具有壁（422），该壁限定从近端到远端延伸穿过膜的内腔，所述内腔具有第一内径和经皮医疗装置具有大于第一内径的最大外径，其中所述膜构造成允许所述医疗装置通过所述内腔，并且其中所述膜包括沿着内表面凹陷的多个纵向定向通道（450）的墙。医疗器械输送护套可以包括形成为波浪形横截面的聚合物材料的管状第一层（222），其具有多个裂片（230）和多个谷物（240），其中第一层材料是可弹性膨胀的在从松弛构型到膨胀构型的径向方向上，并且其中所述第一材料层在轴向上基本上不可膨胀。

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