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1. 发明申请

WO2009157966A1 HIGH FREQUENCY MULTI-AXIS SIMULATION SYSTEM 审中-公开
标题翻译：高频多轴仿真系统
公开(公告)号：WO2009157966A1
公开(公告)日：2009-12-30
申请号：PCT/US2008/083721
申请日：2008-11-17
申请人： BOSE CORPORATION , DINGMANN, David L. , GAGNER, Eric T. , NICKEL, Troy D. , SEEMAN, Steven R. , WHITE, Andrew D.
发明人： DINGMANN, David L. , GAGNER, Eric T. , NICKEL, Troy D. , SEEMAN, Steven R. , WHITE, Andrew D.
IPC分类号： G01N3/32
CPC分类号： G01N3/32 , G01N2203/0008 , G01N2203/0026 , G01N2203/0208 , G01N2203/0264 , G01N2203/027
摘要： A multi-axis fatigue testing device includes a multi-axis test fixture having a multiple input, multiple output mechanical linkage driven by a plurality of actuators and a controller operating each of the plurality of actuators in real time and in synchronization to produce user-defined multiple fatigue cycle profiles. At least one of the actuators driving the mechanical linkage acts against an artificial load characterized by a stiffness. The stiffness is selected to increase a resonance frequency of the test fixture to allow fatigue testing at higher frequencies for a wider range of samples.
摘要翻译：多轴疲劳测试装置包括多轴测试夹具，其具有由多个致动器驱动的多输入多输出机械联动器和实时地并且同步地产生用户定义的多个致动器中的每一个的控制器多个疲劳循环曲线。驱动机械连杆的致动器中的至少一个作用于以刚度为特征的人造负载。选择刚度以增加测试夹具的共振频率，以允许在更宽范围的样品的较高频率下的疲劳测试。

2. 发明申请

WO2009139795A1 MULTI-SAMPLE CONDITIONING SYSTEM 审中-公开
标题翻译：多样品调节系统
公开(公告)号：WO2009139795A1
公开(公告)日：2009-11-19
申请号：PCT/US2008/084538
申请日：2008-11-24
申请人： BOSE CORPORATION , OWENS, Aaron M. , DINGMANN, David L. , NICKEL, Troy D. , SEEMAN, Steven R.
发明人： OWENS, Aaron M. , DINGMANN, David L. , NICKEL, Troy D. , SEEMAN, Steven R.
IPC分类号： G01N3/04
CPC分类号： G01N3/32 , G01N2203/0222 , G01N2203/0242 , G01N2203/027 , G01N2203/0435 , G01N2203/0447 , G01N2203/0476
摘要： A multi-sample conditioning system may include a sample chamber for each sample or a sample chamber holding one or more samples. Multiple samples enable replication for statistical analysis and individual sample chambers enable individual nutrient flow profiles for each sample. A mechanical imbalance may be created when a sample chamber is removed or when samples of different stiffness are conditioned together. The mechanical imbalance may result in an undesired alteration of the desired conditioning profile and increase the variation in the conditioning profile applied to each sample. An asymmetric-loading support assembly provides a low friction support to reduce the undesired alteration of the desired conditioning profile applied to the samples and reduce unwanted reaction loads on the conditioning drive mechanisms. The asymmetric-loading support assembly preferably includes a flexure as the low-friction, high-stiffness support. Other examples that can provide low-friction, high-stiffness support include air bearings, magnetic bearings, and hydraulic bearings.
摘要翻译：多样品调节系统可以包括用于每个样品的样品室或容纳一个或多个样品的样品室。多个样品能够进行统计分析的复制，并且每个样品室可以对每个样品进行单独的营养物流量分布。当样品室被移除或不同刚度的样品被调节在一起时，可能产生机械不平衡。机械不平衡可能导致期望的调节曲线的不期望的改变并且增加了施加到每个样品的调理轮廓的变化。不对称加载支撑组件提供低摩擦支撑以减少施加到样品的期望的调节曲线的不期望的改变，并减少调节驱动机构上的不必要的反应负荷。不对称加载支撑组件优选地包括作为低摩擦，高刚度支撑件的挠曲。可以提供低摩擦，高刚度支撑的其他实例包括空气轴承，磁性轴承和液压轴承。

3. 发明申请

WO2009014942A1 SYSTEM AND METHOD FOR STIMULATION AND CHARACTERIZATION OF BIOLOGIC MATERIALS 审中-公开
标题翻译：用于生物材料刺激和表征的系统和方法
公开(公告)号：WO2009014942A1
公开(公告)日：2009-01-29
申请号：PCT/US2008/070084
申请日：2008-07-15
申请人： BOSE CORPORATION , DINGMANN, David L. , CONATI, Frank C. , NICKEL, Troy D. , OWENS, Aaron M. , WILLIAMS, Chrysanthi
发明人： DINGMANN, David L. , CONATI, Frank C. , NICKEL, Troy D. , OWENS, Aaron M. , WILLIAMS, Chrysanthi
IPC分类号： G01N3/12 , A61F2/06 , A61F2/24
CPC分类号： G01N3/08 , A61F2/042 , A61F2/06 , A61F2/062 , A61F2002/046 , G01N35/1097 , G01N2203/0016 , G01N2203/0048 , G01N2203/0089 , G01N2203/0222 , G01N2203/0242 , G01N2203/0246 , G01N2203/0476
摘要： A multi-sample biologic material stimulation and characterization system includes individual flow paths for each sample. Each individual flow path can maintain sterile conditions and may be chemically monitored. The mean flow rate and pulsatile flow rate through each sample may be individually controlled. Pressure at the sample is controlled independently of the flow rate through downstream variable flow restrictors. An axial force may be applied to each sample. A radial force may be applied via hydrostatic pressure of chamber fluid surrounding each sample. A real-time controller manages the system and saves information gathered from the transducers and actuators of the system.
摘要翻译：多样本生物材料刺激和表征系统包括每个样品的单独流动路径。每个单独的流动路径可以保持无菌条件并且可以进行化学监测。可以单独控制通过每个样品的平均流速和脉动流量。样品的压力独立于通过下游可变流量限制器的流量进行控制。可以向每个样品施加轴向力。可以通过围绕每个样品的腔室流体的静水压力施加径向力。实时控制器管理系统并保存从传感器和系统执行器收集的信息。

4. 发明申请

WO2008151225A1 BEND TOOL 审中-公开
标题翻译：弯曲工具
公开(公告)号：WO2008151225A1
公开(公告)日：2008-12-11
申请号：PCT/US2008/065747
申请日：2008-06-04
申请人： BOSE CORPORATION , CHINAVARE, Jason , DINGMANN, David L. , NICKEL, Troy D.
发明人： CHINAVARE, Jason , DINGMANN, David L. , NICKEL, Troy D.
IPC分类号： G01N3/32
CPC分类号： G01N3/32 , A61F2/82 , A61F2240/008 , G01N2203/0023 , G01N2203/0256 , G01N2203/0274 , G01N2203/0688
摘要： A tool for multi-axis mechanical testing of medical implant devices includes a plurality of pins arranged to form a contacting surface with a sample holder. The pins maintain rolling contact with the sample holder during a bending phase of a fatigue cycle and reduce the effects of friction and localized differential strain on the sample holder.
摘要翻译：用于医疗植入装置的多轴机械测试的工具包括布置成与样品保持器形成接触表面的多个销。引脚在疲劳循环的弯曲阶段保持与样品架的滚动接触，并减少摩擦和局部微分应变对样品架的影响。

5. 发明申请

WO2014008092A1 CONTROLLING FLOW AND PRESSURE WAVEFORMS 审中-公开
标题翻译：控制流量和压力波形
公开(公告)号：WO2014008092A1
公开(公告)日：2014-01-09
申请号：PCT/US2013/048193
申请日：2013-06-27
申请人： BOSE CORPORATION , NICKEL, Troy D. , OWENS, Aaron M. , DINGMANN, David Louis , GRAEN, Matthew D. , WHITE, Andrew D.
发明人： NICKEL, Troy D. , OWENS, Aaron M. , DINGMANN, David Louis , GRAEN, Matthew D. , WHITE, Andrew D.
IPC分类号： G01N3/32 , C12M1/34
CPC分类号： G05D7/0682 , A61F2240/008 , G01N2203/0048 , G01N2203/0089 , Y10T137/0318 , Y10T137/85978
摘要： An apparatus for controlling fluid flow characteristics includes a fluid conduit (12) for containing a fluid, a first dynamic pump (16) connected to a first portion of the conduit, a second dynamic pump (18) connected to a second portion of the conduit and a controller (20) for operating the first and second dynamic pumps to control dynamic flow of the fluid and dynamic pressure in the fluid in the conduit.
摘要翻译：一种用于控制流体流动特性的装置包括用于容纳流体的流体导管（12），连接到导管的第一部分的第一动态泵（16），连接到导管的第二部分的第二动态泵以及用于操作第一和第二动态泵以控制流体的动态流动和管道中的流体中的动态压力的控制器（20）。

6. 发明申请

WO2014031439A1 ELECTROMAGNETIC MOTOR 审中-公开
标题翻译：电磁马达
公开(公告)号：WO2014031439A1
公开(公告)日：2014-02-27
申请号：PCT/US2013/055148
申请日：2013-08-15
申请人： BOSE CORPORATION , ANDRIKOWICH, Tom , NICKEL, Troy D.
发明人： ANDRIKOWICH, Tom , NICKEL, Troy D.
IPC分类号： H02K33/16
CPC分类号： H02K41/02 , H02K5/04 , H02K7/08 , H02K7/14 , H02K33/16 , H02K2201/18
摘要： An electromagnetic motor includes a stator and an armature arranged to move substantially linearly relative to the stator in an intended direction during operation of the motor. A first and second flexure are connected to a first end of the armature. Each flexure has a longest portion which lies substantially in a plane that intersects a plane in which the armature lies at a substantially right angle. The flexures allow motion of the armature in the intended direction while resisting motion of the armature in one or more other degrees of freedom.
摘要翻译：电磁电动机包括定子和电枢，其被布置成在电动机的操作期间相对于定子在预定方向上基本上线性地移动。第一和第二挠曲件连接到电枢的第一端。每个挠曲件具有最长部分，该部分基本上位于与电枢位于大致直角的平面相交的平面中。弯曲允许电枢在预期方向上的运动，同时抵抗电枢在一个或多个其他自由度中的运动。

7. 发明申请

WO2009003081A2 SYSTEM AND METHOD FOR MULTI-AXES SIMULATION 审中-公开
标题翻译：用于多轴模拟的系统和方法
公开(公告)号：WO2009003081A2
公开(公告)日：2008-12-31
申请号：PCT/US2008/068285
申请日：2008-06-26
申请人： BOSE CORPORATION , NICKEL, Troy D. , DEVILEY, David J.
发明人： NICKEL, Troy D. , DEVILEY, David J.
IPC分类号： G01N3/00
CPC分类号： G01N3/32 , G01N2203/0073 , G01N2203/0208 , G01N2203/0435
摘要： A multi-axis fatigue testing device includes a multiple input, multiple output mechanical linkage driven by a plurality of actuators and a controller operating each of the plurality of actuators in real time and in synchronization to produce user-defined multiple fatigue cycle profiles.
摘要翻译：多轴疲劳测试装置包括由多个致动器驱动的多输入多输出机械联动器和实时地并且同步地操作多个致动器中的每一个的控制器，以产生用户定义的多个疲劳循环轮廓。

8. 发明申请

WO2013095834A1 SYSTEM FOR MECHANICAL STIMULATION AND CHARACTERIZATION OF BIOLOGIC SAMPLES 审中-公开
标题翻译：用于机械刺激和生物样品表征的系统
公开(公告)号：WO2013095834A1
公开(公告)日：2013-06-27
申请号：PCT/US2012/065756
申请日：2012-11-19
申请人： BOSE CORPORATION , WILLIAMS, Chrysanthi , NICKEL, Troy D. , JACOBITES, Brock N. , MALKASIAN, Harry , OWENS, Aaron M.
发明人： WILLIAMS, Chrysanthi , NICKEL, Troy D. , JACOBITES, Brock N. , MALKASIAN, Harry , OWENS, Aaron M.
IPC分类号： G01N3/32
CPC分类号： G01N3/32 , C12M35/04 , G01N2203/0089 , G01N2203/0242 , G01N2203/0274
摘要： A system for applying mechanical stimulation to a biologic sample includes a first biologic sample chamber having a biologic sample holder therein, a support structure for holding the first biologic sample chamber, and a first actuator that can supply a mechanical load to a biologic sample held by the biologic sample holder. The actuator is configured to move into a first position proximate to the chamber in which the actuator can transmit the load to the biologic sample via a first transmission path that includes the biologic sample holder. A controller is configured to automatically move the first actuator into the first position.
摘要翻译：用于对生物样品施加机械刺激的系统包括其中具有生物样本保持器的第一生物样品室，用于保持第一生物样品室的支撑结构，以及能够将机械载荷提供给由生物样品架。致动器被配置成移动到靠近腔室的第一位置，致动器可以通过包括生物样本保持器的第一传输路径将负载传递到生物样本。控制器被配置为自动地将第一致动器移动到第一位置。

9. 发明申请

WO2015006204A2 SECURING APPARATUS AND METHOD 审中-公开
标题翻译：安全装置和方法
公开(公告)号：WO2015006204A2
公开(公告)日：2015-01-15
申请号：PCT/US2014/045557
申请日：2014-07-07
申请人： BOSE CORPORATION
发明人： ZHANG, Guangtian , NICKEL, Troy D. , RAUSCH, Eugene J. , OWENS, Aaron M.
IPC分类号： C12M1/107
CPC分类号： C12M35/04 , C12M21/08 , C12N2527/00
摘要： A securing apparatus includes a housing, a cam member, and a movable device that can be moved in a first direction to engage a first surface of the cam member to cause the cam member to move from a first position to a second position. When the cam member is in the first position, first and second movable members can be moved relative to the housing. When the cam member is in the second position, second and third surfaces of the cam member press respectively against the first and second movable members to trap the first and second movable members respectively between the second and third surfaces of the cam member and the housing such that the first and second movable members are fixed relative to the housing.
摘要翻译：固定装置包括壳体，凸轮构件和可移动装置，其可沿第一方向移动以接合凸轮构件的第一表面，以使凸轮构件从第一位置移动到第二位置。当凸轮构件处于第一位置时，第一和第二可移动构件可相对于壳体移动。当凸轮构件处于第二位置时，凸轮构件的第二和第三表面分别压靠在第一和第二可动构件上，以将第一和第二可动构件分别夹在凸轮构件和壳体的第二和第三表面之间第一和第二可动构件相对于壳体是固定的。

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