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1. 发明申请

WO2007014126A3 PARTIAL PRESSURE SWING ADSORPTION SYSTEM FOR PROVIDING HYDROGEN TO A VEHICLE FUEL CELL 审中-公开
公开(公告)号：WO2007014126A3
公开(公告)日：2007-02-01
申请号：PCT/US2006/028612
申请日：2006-07-24
申请人： BLOOM ENERGY CORPORATION , MCELROY, James , FINN, John , LEVAN, M., Douglas , VENKATARAMAN, Swaminathan , MITLITSKY, Fred
发明人： MCELROY, James , FINN, John , LEVAN, M., Douglas , VENKATARAMAN, Swaminathan , MITLITSKY, Fred
IPC分类号： B01D53/02
摘要： A method of operating a fuel cell system includes providing a fuel inlet stream into a fuel cell stack, operating the fuel cell stack to generate electricity and a hydrogen containing fuel exhaust stream, separating at least a portion of hydrogen contained in the fuel exhaust stream using partial pressure swing adsorption, and providing the hydrogen separated from the fuel exhaust stream to a hydrogen storage vessel or to a hydrogen using device.

2. 发明申请

WO2007014127A2 FUEL CELL SYSTEM WITH PARTIAL RECYCLING OF ANODE EXHAUST 审中-公开
标题翻译：部分回收阳极废气的燃料电池系统
公开(公告)号：WO2007014127A2
公开(公告)日：2007-02-01
申请号：PCT/US2006/028613
申请日：2006-07-24
申请人： ION AMERICA CORPORATION , MCELROY, James , VENKATARAMAN, Swaminathan , FINN, John , LEVAN, M., Douglas , MITLITSKY, Fred
发明人： MCELROY, James , VENKATARAMAN, Swaminathan , FINN, John , LEVAN, M., Douglas , MITLITSKY, Fred
IPC分类号： H01M8/18
CPC分类号： H01M8/04097 , H01M8/04007 , H01M8/04231 , H01M8/0612 , H01M8/0668 , H01M2008/1293
摘要： A method of operating a fuel cell system includes providing a fuel inlet stream into a fuel cell stack, operating the fuel cell stack to generate electricity and a hydrogen containing fuel exhaust stream having a temperature above 200 C, lowering a temperature of the fuel exhaust stream to 200 C or less, separating the fuel exhaust stream into a first separated fuel exhaust stream and a second separated fuel exhaust stream, and recycling the first separated fuel exhaust stream into the fuel inlet stream.
摘要翻译：操作燃料电池系统的方法包括将燃料入口流提供到燃料电池堆中，操作燃料电池堆以产生电力和具有高于200℃的温度的含氢燃料废气流，将燃料排出物流的温度降低至200℃或更低，将燃料排出物流分离成第一分离的燃料排出物流和第二分离的燃料排出物流，并将第一分离的燃料排出物流循环至燃料入口物流中。 p>

3. 发明申请

WO2007014129A1 GAS SEPARATION METHOD AND APPARATUS USING PARTIAL PRESSURE SWING ADSORPTION 审中-公开
标题翻译：气体分离方法和使用部分压力振荡吸附的装置
公开(公告)号：WO2007014129A1
公开(公告)日：2007-02-01
申请号：PCT/US2006/028615
申请日：2006-07-24
申请人： ION AMERICA CORPORATION , LEVAN, M., Douglas , FINN, John , MCELROY, James
发明人： LEVAN, M., Douglas , FINN, John , MCELROY, James
IPC分类号： B01D53/02
CPC分类号： B01D53/047 , B01D2253/102 , B01D2253/104 , B01D2253/106 , B01D2253/108 , B01D2256/16 , B01D2257/108 , B01D2257/504 , B01D2257/80 , B01D2258/0208 , B01D2259/40062 , C01B3/384 , C01B3/48 , C01B3/56 , C01B2203/0233 , C01B2203/0283 , C01B2203/043 , C01B2203/0475 , C01B2203/066 , C01B2203/067 , C01B2203/0805 , C01B2203/0811 , C01B2203/0822 , C01B2203/0827 , C01B2203/1241 , C01B2203/148 , C01B2203/86 , H01M8/04171 , H01M8/0668 , H01M2008/1293 , H01M2008/147 , Y02C10/08 , Y02E60/526 , Y02E60/566 , Y02P20/128 , Y02P20/152 , Y02P30/30
摘要： A four-step partial pressure swing adsorption method and apparatus is provided for gas separation, such as for recovering fuel from the fuel exhaust of a fuel cell stack. A method of operating a fuel cell system includes providing a fuel inlet stream into a fuel cell stack, operating the fuel cell stack to generate electricity and a hydrogen containing fuel exhaust stream, separating at least a portion of hydrogen contained in the fuel exhaust stream using partial pressure swing adsorption, and providing the hydrogen separated from the fuel exhaust stream into the fuel inlet stream.
摘要翻译：提供了用于气体分离的四级分压变压吸附方法和装置，例如用于从燃料电池堆的燃料排放中回收燃料。操作燃料电池系统的方法包括将燃料入口流提供到燃料电池堆中，操作燃料电池堆以发电和含氢燃料排出流，使用在燃料排气流中的氢气中的至少一部分分离，使用并且将从燃料排出流分离的氢提供到燃料入口流中。

4. 发明申请

WO2004038885A2 SOLID OXIDE REGENERATIVE FUEL CELL 审中-公开
标题翻译：固体氧化物再生燃料电池
公开(公告)号：WO2004038885A2
公开(公告)日：2004-05-06
申请号：PCT/US2003/029127
申请日：2003-10-15
申请人： ION AMERICA CORPORATION , MCELROY, James , GOTTMANN, Matthias , FINN, John , MITLITSKY, Fred
发明人： MCELROY, James , GOTTMANN, Matthias , FINN, John , MITLITSKY, Fred
IPC分类号： H02J
CPC分类号： H01M8/184 , H01M8/04067 , H01M8/182 , H01M2008/1293 , Y02E60/528
摘要： A Solid Oxide Regenerative Fuel Cell (SORFC) system stores waste heat from the fuel cell in a heat storage material during the discharge mode. The heat is then used to heat water to be electrolyzed during the charge mode.
摘要翻译：在放电模式期间，固体氧化物再生燃料电池（SORFC）系统将来自燃料电池的废热储存在储热材料中。然后，在充电模式期间，将热量加热以进行电解。

5. 发明申请

WO2005069776A2 HIGH TEMPERATURE FUEL CELL SYSTEM AND METHOD OF OPERATING SAME 审中-公开
标题翻译：高温燃料电池系统及其运行方法
公开(公告)号：WO2005069776A2
公开(公告)日：2005-08-04
申请号：PCT/US2004/041082
申请日：2004-12-09
申请人： ION AMERICA CORPORATION , VENKATARAMAN, Swaminathan , GOTTMAN, Matthias , FINN, John
发明人： VENKATARAMAN, Swaminathan , GOTTMAN, Matthias , FINN, John
IPC分类号： B01J8/02 , B01J19/24 , C01B3/38 , C01B3/48 , C01B3/56 , H01M8/00 , H01M8/04 , H01M8/06 , H01M8/10 , H01M8/12 , H01M8/18 , H01M8/24
CPC分类号： H01M8/04007 , B01J8/0257 , B01J8/0285 , B01J19/249 , B01J2208/00309 , B01J2208/00716 , B01J2219/00006 , B01J2219/2465 , B01J2219/2479 , B01J2219/2481 , C01B3/384 , C01B3/48 , C01B3/56 , C01B2203/0233 , C01B2203/0283 , C01B2203/043 , C01B2203/0475 , C01B2203/0495 , C01B2203/066 , C01B2203/0811 , C01B2203/0822 , C01B2203/1035 , C01B2203/1241 , C01B2203/127 , C01B2203/1294 , H01M8/04022 , H01M8/04097 , H01M8/04164 , H01M8/04268 , H01M8/0612 , H01M8/0625 , H01M8/0668 , H01M8/0675 , H01M8/12 , H01M8/18 , H01M8/2425 , H01M8/249 , H01M2008/1293 , Y02E60/528 , Y02P20/128 , Y02P20/129
摘要： A high temperature fuel cell stack system, such as a solid oxide fuel cell system, with an improved balance of plant efficiency includes a thermally integrated reformer, combustor and the fuel cell stack.
摘要翻译：具有改进的工厂效率平衡的高温燃料电池堆系统（例如固体氧化物燃料电池系统）包括热集成重整器，燃烧器和燃料电池堆。

6. 发明申请

WO2012125746A1 TRICYCLIC GYRASE INHIBITORS 审中-公开
公开(公告)号：WO2012125746A1
公开(公告)日：2012-09-20
申请号：PCT/US2012/029104
申请日：2012-03-14
申请人： TRIUS THERAPEUTICS INC. , LAWRENCE LIVERMORE NATIONAL SECURITY, LLC , BENSEN, Daniel , FINN, John , LEE, Suk, Joong , CHEN, Zhiyong , LAM, Thanh, To , LI, Xiaoming , TRZOSS, Michael , JUNG, Michael , NGUYEN, Toan, B. , LIGHTSTONE, Felice , TARI, Leslie, William , ZHANG, Junhu , ARISTOFF, Paul , PHILLIPSON, Douglas, W. , WONG, Sergio, E.
发明人： BENSEN, Daniel , FINN, John , LEE, Suk, Joong , CHEN, Zhiyong , LAM, Thanh, To , LI, Xiaoming , TRZOSS, Michael , JUNG, Michael , NGUYEN, Toan, B. , LIGHTSTONE, Felice , TARI, Leslie, William , ZHANG, Junhu , ARISTOFF, Paul , PHILLIPSON, Douglas, W. , WONG, Sergio, E.
IPC分类号： C07D487/04 , C07D487/14 , A61K31/495 , A61P31/04
CPC分类号： C07D487/04 , C07D487/14
摘要： Disclosed herein are compounds having the structure of Formula I and pharmaceutically suitable salts, esters, and prodrugs thereof that are useful as antibacterially effective tricyclic gyrase inhibitors. Related pharmaceutical compositions, uses and methods of making the compounds are also contemplated.
摘要翻译：本文公开了具有式I结构的化合物及其药学上合适的盐，酯和前药，其可用作抗菌三环类回旋酶抑制剂。还考虑了相关的药物组合物，用途和制备化合物的方法。

7. 发明申请

WO2011032050A2 GYRASE INHIBITORS 审中-公开
标题翻译： GYRASE抑制剂
公开(公告)号：WO2011032050A2
公开(公告)日：2011-03-17
申请号：PCT/US2010/048538
申请日：2010-09-10
申请人： TRIUS THERAPEUTICS, INC. , CREIGHTON, Chris , TARI, Les , CHEN, Zhiyong , HILGERS, Mark , LAM, Thanh , LI, Xiaoming , TRZOSS, Michael , ZHANG, Junhu , FINN, John
发明人： CREIGHTON, Chris , TARI, Les , CHEN, Zhiyong , HILGERS, Mark , LAM, Thanh , LI, Xiaoming , TRZOSS, Michael , ZHANG, Junhu , FINN, John
IPC分类号： C07D487/04 , C07D519/00 , A61K31/519 , A61P31/00
CPC分类号： C07D519/00 , C07D471/04 , C07D471/16 , C07D487/04 , C07D487/16 , C07D491/048 , C07D513/04
摘要： Novel gyrase inhibitors and related compositions and methods are useful for impeding bacterial growth. Compounds of Formula (I), are disclosed: Formula (I), wherein Y is N or CH; Z is N or CR 5 ; R 5 is H, a substituted or unsubstituted hydrocarbyl residue (1-3C) containing 0-2 heteroatoms selected from O, S and N, or is an inorganic residue; L is O, S, NR 7 , or CR 8 R 9 ; R 7 is H or C 1-3 alkyl; R 8 and R 9 are each independently H or C 1-3 alkyl; R 2 is H, a hydrocarbyl residue (1-40C) containing 0-10 heteroatoms selected from O, S and N optionally substituted with an inorganic residue; R 4 is H, an inorganic residue, or a hydrocarbyl residue (1-30C) containing 0- 12 heteroatoms selected from O, S and N and containing 0-10 inorganic residues, wherein R 5 and R 4 together may join to form a fused ring; and R 6 is selected from the group consisting of H, C 1-5 alkyl, C 2-5 alkenyl, C 2-5 alkynyl, halo C 1-5 alkyl, halo C 2-5 alkenyl, halo C 2-5 alkynyl, C 1-5 hydroxyalkyl, C 1-5 alkyl chloride, C 2-5 alkenyl chloride, and C 2-5 alkynyl chloride; or a pharmaceutically-acceptable salt, ester, or prodrug thereof.
摘要翻译：新型促旋酶抑制剂和相关组合物和方法可用于阻止细菌生长。公开了式（I）的化合物：式（I），其中Y是N或CH; Z为N或CR5; R5是H，含有0-2个选自O，S和N的杂原子的取代或未取代的烃基残基（1-3C），或是无机残基; L是O，S，NR7或CR8R9; R7是H或C1-3烷基; R 8和R 9各自独立地为H或C 1-3烷基; R2是H，含有0-10个选自O，S和N的杂原子的烃基残基（1-40℃），任选被无机残基取代; R4是H，无机残基，或含有0-12个选自O，S和N的杂原子并含有0-10个无机残基的烃基残基（1-30℃），其中R 5和R 4可以连接形成稠环; 并且R 6选自H，C 1-5烷基，C 2-5烯基，C 2-5炔基，卤代C 1-5烷基，卤素C 2-5烯基，卤代C 2-5炔基，C 1-5羟基烷基，C 1 -5烷基氯，C2-5烯基氯和C2-5炔基氯; 或其药学上可接受的盐，酯或前药。

8. 发明申请

WO2005035764A1 AUTOGENE NUCLEIC ACIDS ENCODING A SECRETABLE RNA POLYMERASE 审中-公开
标题翻译：自由核酸编码一种秘密的RNA聚合酶
公开(公告)号：WO2005035764A1
公开(公告)日：2005-04-21
申请号：PCT/CA2004/001866
申请日：2004-10-14
申请人： THE UNIVERSITY OF BRITISH COLUMBIA , FINN, John , MACLACHLAN, Ian
发明人： FINN, John , MACLACHLAN, Ian
IPC分类号： C12N15/62
CPC分类号： C12N9/1247 , A61K31/7088 , A61K48/00 , C07K2319/10 , C12N15/85 , C12N2830/42 , C12N2840/203 , C12N2840/206
摘要： This invention provides methods, nucleic acids, compounds, and compositions for expressing a product of interest in a cell that involve a secretable RNA Polymerase.
摘要翻译：本发明提供用于在涉及可分泌的RNA聚合酶的细胞中表达感兴趣的产物的方法，核酸，化合物和组合物。

9. 发明申请

WO2002088370A3 AUTOGENE NUCLEIC ACIDS ENCODING A SECRETABLE RNA POLYMERASE 审中-公开
公开(公告)号：WO2002088370A3
公开(公告)日：2002-11-07
申请号：PCT/CA2002/000670
申请日：2002-04-30
申请人： PROTIVA BIOTHERAPEUTICS INC. , FINN, John , MACLACHLAN, Ian
发明人： FINN, John , MACLACHLAN, Ian
IPC分类号： C12N15/85
摘要： The invention provides methods, nucleic acids, compounds, and compositions for expressing a product of interest in a cell that involve a secretable RNA Polymerase.

10. 发明申请

WO2011153310A1 DIHYDROFOLATE REDUCTASE INHIBITORS 审中-公开
标题翻译：二氢叶酸还原酶抑制剂
公开(公告)号：WO2011153310A1
公开(公告)日：2011-12-08
申请号：PCT/US2011/038871
申请日：2011-06-02
申请人： TRIUS THERAPEUTICS , CHEN, Zhiyong , CREIGHTON, Chris , CUNNINGHAM, Mark , FINN, John , HILGERS, Mark , JUNG, Michael , KOHNEN, Lucy, Aguirre , LAM, Thanh , LI, Xiaoming , STIDHAM, Mark , TARI, Les , TRZOSS, Michael , ZHANG, Junhu
发明人： CHEN, Zhiyong , CREIGHTON, Chris , CUNNINGHAM, Mark , FINN, John , HILGERS, Mark , JUNG, Michael , KOHNEN, Lucy, Aguirre , LAM, Thanh , LI, Xiaoming , STIDHAM, Mark , TARI, Les , TRZOSS, Michael , ZHANG, Junhu
IPC分类号： A01N43/54 , C07D239/42 , C07D401/04
CPC分类号： C07D401/14 , C07D239/95 , C07D417/14
摘要： The present disclosure provides compounds of Formula I: (I) or a pharmaceutically acceptable salt thereof, wherein R 5 , R 6 and Z are as described herein. The disclosure also provides pharmaceutical compositions thereof; and methods for inhibiting DHFR activity; and methods for treating cell proliferative diseases, autoimmune disease, inflammatory disease or bacterial, fungal or parasitic infection by administering a compound of Formula I.
摘要翻译：本公开提供式I化合物：（I）或其药学上可接受的盐，其中R 5，R 6和Z如本文所述。本公开还提供其药物组合物; 和抑制DHFR活性的方法; 以及通过给予式I化合物治疗细胞增殖性疾病，自身免疫疾病，炎性疾病或细菌，真菌或寄生虫感染的方法。

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