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    • 1. 发明申请
    • COMPACT MULTIMODALITY OPTICAL COHERENCE TOMOGRAPHY IMAGING SYSTEMS AND RELATED METHODS AND COMPUTER PROGRAM PRODUCTS
    • 紧凑的多模式光学相干成像系统及相关方法和计算机程序产品
    • WO2012018991A3
    • 2012-05-03
    • PCT/US2011046559
    • 2011-08-04
    • BIOPTIGEN INCHUENING PETEHART ROBERT HBUCKLAND ERIC LBOWER BRADLEY A
    • HUENING PETEHART ROBERT HBUCKLAND ERIC LBOWER BRADLEY A
    • A61B3/12
    • A61B3/102A61B3/14G01B9/0203G01B9/02091
    • Systems for imaging a sample are provided. The system includes an optical coherence tomography (OCT) imaging portion having an associated OCT path (201) defined by one set of optical elements between an OCT signal delivery optical fiber and the sample; an image capture portion having an associated image capture path (202) defined by a second set of optical elements between an image capture device and the sample, different from the OCT path; and an illuminator portion having an associated illumination path (203) defined by a third set of optical elements between an illumination source and the sample. The OCT path, the image capture path, and the illuminator path have at least one optical element (207) in common, and the respective paths differ from each other by at least one optical element. The OCT path and the image capture path share a common intermediate conjugate image plane (206). Focal control is achieved for the OCT path and the image capture path concurrently through adjustment of one or more common optical elements distal to the common intermediate conjugate plane, such that focal control requires no differential adjustment between optical elements not in common to both paths.
    • 提供了用于成像样本的系统。 该系统包括光学相干断层摄影(OCT)成像部分,其具有由OCT信号传送光纤和样本之间的一组光学元件限定的相关OCT路径(201) 图像捕获部分具有与OCT路径不同的图像捕获装置和样本之间的第二组光学元件所定义的相关图像捕获路径; 以及照明器部分,具有由照明源和样本之间的第三组光学元件限定的相关联的照明路径(203)。 OCT路径,图像捕获路径和照明器路径具有共同的至少一个光学元件(207),并且各个路径由至少一个光学元件彼此不同。 OCT路径和图像捕获路径共享公共中间共轭像平面(206)。 通过调整远离公共中间共轭平面的一个或多个共同的光学元件,通过同时进行OCT路径和图像捕获路径的焦点控制,使得焦点控制不需要在两个路径不共同的光学元件之间进行差分调整。