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1. 发明申请

WO2019215471A1 HANDHELD METERED DOSE INHALER 审中-公开
公开(公告)号：WO2019215471A1
公开(公告)日：2019-11-14
申请号：PCT/IB2018/000685
申请日：2018-05-11
申请人： BIOCORP PRODUCTION S.A. , MARCOZ, Alain , PEREIRA, Alexandre , POLLARD, Mathieu
发明人： MARCOZ, Alain , PEREIRA, Alexandre , POLLARD, Mathieu
IPC分类号： A61M15/00
摘要： The present invention relates to a metered dose inhaler (MDI) device comprising a mechanically activated visual cue (70, 72, 81) representing a number of doses expelled from, or doses remaining in, a drug-containing cartridge or canister (3) locatable within a body of said MDI, wherein the visual cue is visible through at least a portion of the body of said MDI, and a removable data processing system (18) configured to verify the dose of drug administered and/ or inhaled, wherein the MDI device further comprises a correlation system (19) configured to correlate physically released doses from the drug containing cartridge or canister with the administration and/ or inhalation data stored in the removable data processing system.

2. 发明申请

WO2019175615A8 DOSE CONTROL DEVICE FOR INJECTABLE-DRUG DELIVERY DEVICES 审中-公开
公开(公告)号：WO2019175615A8
公开(公告)日：2019-09-19
申请号：PCT/IB2018/000426
申请日：2018-03-14
申请人： BIOCORP PRODUCTION S.A.
发明人： MARCOZ, Alain , PEREIRA, Alexandre , POLLARD, Mathieu
IPC分类号： A61M5/315
摘要： Dose control device for a handheld pen-type injectable-drug delivery device, the handheld pen-type injectable-drug delivery device comprising an elongate body with a proximal and distal extremity, a longitudinal axis extending from the proximal extremity to the distal extremity, and a rotatable dose setting wheel located at said proximal extremity, wherein said dose control device comprises a magnetic field producing means located at the proximal extremity of said elongate body; one or more magnetic field sensors in communication with a data processing unit located on an outer surface of, or inside, the elongate body; and a clutch assembly configured to selectively move the magnetic field producing means from a first, engaged, position, to a second, disengaged, position.

3. 发明申请

WO2017013464A1 DOSE CONTROL DEVICE FOR INJECTABLE-DRUG DELIVERY DEVICES 审中-公开
标题翻译：用于注射式药物递送装置的剂量控制装置
公开(公告)号：WO2017013464A1
公开(公告)日：2017-01-26
申请号：PCT/IB2015/001784
申请日：2015-07-21
申请人： BIOCORP PRODUCTION S.A.
发明人： MARCOZ, Alain , JEZ, Emmanuel , DIOGO, Sylvain , GOURBET, Patrice , PEREIRA, Alexandre , POLLARD, Mathieu , GILLET, Kévin
IPC分类号： A61M5/315 , G01D5/14 , G01R33/02
CPC分类号： A61M5/31533 , A61M2005/3126 , A61M2205/3317 , A61M2205/3368 , A61M2205/3553 , A61M2205/3561 , A61M2205/60 , A61M2209/00 , G01D5/145 , G01R33/0206
摘要： The present invention relates to a dose control device adapted to be removably mounted onto an exterior peripheral surface of an injectable drug delivery device, the drug delivery device comprising a substantially elongate drug delivery body, at least one injectable drug held by the body, the body having a distal and proximal extremity, wherein the dose control device comprises a first component configured to fit and substantially encase at least a portion of an exterior peripheral surface of said drug delivery device, and located at a proximal extremity of said drug delivery device; a second component configured to fit and substantially encase a corresponding remaining unencased portion of the exterior peripheral surface of said drug delivery device, and also located at a proximal extremity of said drug delivery device; wherein said first component and said second component removably engage with each other to form a unit having a longitudinal bore that extends along a longitudinal axis of said drug delivery device, and in which bore the drug delivery device is encased between said first component and said second component.
摘要翻译：本发明涉及适于可拆卸地安装在可注射药物输送装置的外周表面上的剂量控制装置，药物递送装置包括基本上细长的药物递送体，由身体保持的至少一种可注射药物，身体其具有远端和近端，其中所述剂量控制装置包括第一部件，所述第一部件构造成适于并基本上包围所述药物递送装置的外周表面的至少一部分并且位于所述药物递送装置的近端处; 第二部件，其构造成适配并基本上包裹所述药物递送装置的外周表面的相应的剩余的未加载部分，并且还位于所述药物递送装置的近端处; 其中所述第一部件和所述第二部件可相互接合以形成具有沿着所述药物输送装置的纵向轴线延伸的纵向孔的单元，并且其中所述药物输送装置被包封在所述第一部件和所述第二部件之间零件。

4. 发明申请

WO2017178865A1 METERED DOSE INHALER ADD-ON DEVICE, OBSERVANCE IMPROVEMENT SYSTEM AND METHOD FOR IMPROVING OBSERVANCE OF USE IN METERED DOSE INHALERS 审中-公开
标题翻译：测量剂量吸入器附加装置，用于改善在计量吸入器中使用的观察改进系统和方法
公开(公告)号：WO2017178865A1
公开(公告)日：2017-10-19
申请号：PCT/IB2016/052070
申请日：2016-04-12
申请人： BIOCORP PRODUCTION S.A
发明人： MARCOZ, Alain , JEZ, Emmanuel , DIOGO, Sylvain , GOURBET, Patrice , PEREIRA, Alexandre , POLLARD, Mathieu , GILLET, Kevin
IPC分类号： A61M15/00
摘要： The present invention relates to an add-on device for a metered dose inhaler, an observance improvement system, and a method for improving observance of use in metered dose inhalers, the add-on device comprising an observance system housing component comprising an observance system with at least one pressure sensor; a mouthpiece component configured to fit, surround and removably engage with an exterior surface of a mouthpiece outlet provided on the metered dose inhaler; wherein said observance system housing is configured to fit and removably engage with said mouthpiece component; and said mouthpiece component is specifically adapted to conform to the exterior surface of the mouthpiece outlet of the metered dose inhaler without obstructing delivery of a dose of drug through said outlet.
摘要翻译：本发明涉及一种用于计量剂量吸入器的附加装置，一种遵守改善系统以及一种用于改善对计量吸入器中使用的遵守的方法，附加装置包括遵守系统外壳部件，其包括具有至少一个压力传感器的观测系统; 咬嘴部件，所述咬嘴部件构造成配合，围绕并且可移除地接合设置在所述定量吸入器上的咬嘴出口的外表面; 其中所述观察系统壳体被构造成配合并可移除地与所述咬嘴部件接合; 并且所述管嘴部件特别适于与定量吸入器的管嘴出口的外表面贴合，而不阻碍通过所述出口输送一定剂量的药物。

5. 发明申请

WO2017013463A1 DOSE CONTROL SYSTEM FOR INJECTABLE-DRUG DELIVERY DEVICES AND ASSOCIATED METHODS OF USE 审中-公开
标题翻译：用于注射式药物递送装置的药物控制系统及相关使用方法
公开(公告)号：WO2017013463A1
公开(公告)日：2017-01-26
申请号：PCT/IB2015/001770
申请日：2015-07-21
申请人： BIOCORP PRODUCTION S.A.
发明人： MARCOZ, Alain , JEZ, Emmanuel , DIOGO, Sylvain , GOURBET, Patrice , PEREIRA, Alexandre , POLLARD, Mathieu , GILLET, Kévin
IPC分类号： A61M5/315 , G01D5/14 , G01R33/02
CPC分类号： A61M5/31533 , A61M2205/3317 , A61M2205/60 , A61M2209/00 , G01D5/145 , G01R33/0206
摘要： The present invention relates to a dose control system adapted for an injectable drug delivery device, the drug delivery device comprising a substantially elongate drug delivery body, at least one injectable drug held by the body, the body having a distal and proximal extremity, wherein the dose control system comprises three-dimensional magnetic field producing means for producing a magnetic field along three axes (x,y,z); magnetic field detection means configured to detect changes in at least the magnetic field produced by the three-dimensional magnetic field producing means; displacement detection means configured to measure a relative displacement or relative movement of the drug delivery device, and an integrated control unit, wherein the integrated control unit is connected to the magnetic field detection means, and to the displacement detection means, for processing information received from both the magnetic field detection means and the displacement detection means; wherein the three-dimensional magnetic field producing means is configured to effect a rotating coaxial displacement around, and along, a longitudinal axis of the drug delivery system; the magnetic field detection means are located along said longitudinal axis; and the three-dimensional magnetic field producing means is located at, or near, a proximal extremity of the body of the drug delivery device.
摘要翻译：本发明涉及适用于可注射药物递送装置的剂量控制系统，药物递送装置包括基本上细长的药物递送体，由身体保持的至少一种可注射药物，身体具有远端和近端，其中，剂量控制系统包括用于沿三个轴（x，y，z）产生磁场的三维磁场产生装置; 磁场检测装置，被配置为检测至少由三维磁场产生装置产生的磁场的变化; 位移检测装置，被配置为测量药物输送装置的相对位移或相对运动;以及集成控制单元，其中所述集成控制单元连接到所述磁场检测装置，以及所述位移检测装置，用于处理从磁场检测装置和位移检测装置两者; 其中所述三维磁场产生装置被配置为实现所述药物递送系统的纵向轴线周围和沿其的旋转同轴位移; 所述磁场检测装置沿着所述纵向轴线定位; 并且三维磁场产生装置位于药物递送装置的主体的近端处或附近。

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