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1. 发明申请

WO2009019043A3 ANALYSIS OF MOLECULAR INTERACTIONS ON AND/OR IN THIN LAYERS 审中-公开
标题翻译：薄层和/或薄层分子间相互作用的研究
公开(公告)号：WO2009019043A3
公开(公告)日：2009-04-30
申请号：PCT/EP2008006587
申请日：2008-08-09
申请人： BIAMETRICS MARKEN UND RECHTE G , GAUGLITZ GUENTER , PROLL GUENTHER , PROELL FLORIAN , STEINLE LUTZ , SCHUBERT MARKUS
发明人： GAUGLITZ GUENTER , PROLL GUENTHER , PROELL FLORIAN , STEINLE LUTZ , SCHUBERT MARKUS
IPC分类号： G01N21/45
CPC分类号： G01N33/54373 , G01N21/45 , G01N21/8422 , G01N33/551
摘要： The invention relates to a carrier for a thin layer and a method for the analysis of molecular interactions on and/or in such a thin layer. A thin layer disposed on a carrier is illuminated with electromagnetic radiation from at least one radiation source and a reflected radiation part on boundary surfaces of the thin layer is detected by means of an optoelectronic converter that converts the detected radiation into a frequency- and intensity-dependant photocurrent. A reading voltage is applied to the optoelectronic converter. By changing the reading voltage, the spectral sensitivity of the optoelectronic converter is varied such that a substantially constant photocurrent is obtained. Alternatively or in addition to varying the spectral sensitivity by changing the reading voltage, the reflected radiation part is detected with an optoelectronic converter that is designed as a sensor layer in the carrier. The carrier is particularly characterized in that it comprises a substrate on which at least one sensor layer with optoelectronic properties is disposed.
摘要翻译：公开了对薄层的支持和用于研究这种薄层上和/或其中的分子相互作用的方法。甲布置在载体膜被照亮与至少一个辐射源的电磁辐射，并通过一个光电转换元件，其检测到的辐射转换成频率和强度相关的光电流的装置探测反射的辐射成分的薄层的边界表面的。读出电压被施加到光电转换器。通过改变读取电压来改变光电换能器的光谱灵敏度，从而获得基本恒定的光电流。可替代地，或除通过改变反射的辐射分量的读出电压的光谱灵敏度的变化是由被设计为在载体中的传感器层的光电换能器检测。载体的特征尤其在于其具有衬底，在该衬底上布置有至少一个传感器层并具有光电特性。

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