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    • 9. 发明申请
    • PROCESS FOR PREPARING 2,1,3-BENZOTHIADIAZOLES
    • 用于生产2,1,3- benzothiadiazoles
    • WO1998027076A1
    • 1998-06-25
    • PCT/EP1997006752
    • 1997-12-03
    • BAYER AKTIENGESELLSCHAFTHEITKÄMPER, Peter
    • BAYER AKTIENGESELLSCHAFT
    • C07D285/14
    • C07D285/14
    • The invention concerns an improved process for preparing 2,1,3-benzothiadiazoles of general formula (I), in which the groups R , R , R and R can be identical or different and designate a hydrogen group or a hydrocarbon atom with between 1 and 4 carbon atoms, by reacting o-phenylene diamines of general formula (II), in which the groups R , R , R and R have the above meanings, with sulphur dioxide. The process is characterized in that gaseous sulphur dioxide is mixed into the o-phenylene diamine to be reacted in the liquid phase in the absence of an additional solvent and in the absence of a catalyst at reaction temperatures of between 50 and 100 DEG C and a pressure of between 0.9 and 1.5 bar.
    • 本发明涉及一种用于制备的改进方法-2,1,3- benzothiadiazoles通式(I),其中,所述基团R <1>,R <2>,R <3>和R <4>相同或不同的 可以是和氢原子的含义或碳原子数为1〜4的烃残基,具有,由通式(II)的邻 - 苯二胺反应,其中基团R <1>,R <2>,R <3>和R <4>具有上面给出,与二氧化硫的含义,其特征在于在反应邻苯二胺在液相在不存在另外的溶剂和在50反应温度至100℃的情况下催化剂的,并在0压力 9干涉至1.5巴气体二氧化硫。