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1. 发明申请

WO2015136254A1 TESTING METHODS AND APPARATUS 审中-公开
标题翻译：测试方法和设备
公开(公告)号：WO2015136254A1
公开(公告)日：2015-09-17
申请号：PCT/GB2015/050677
申请日：2015-03-09
申请人： BACTEST LIMITED
发明人： RICKETT, Toby William , PRICE, Derek , BROOKING, Annie
IPC分类号： C12Q1/04 , C12M1/34
CPC分类号： C12Q1/04 , C12M23/34 , C12M37/00 , C12M41/12 , C12M41/36 , C12M41/40 , C12M41/46 , C12Q1/045
摘要： We describe a method of selectively testing a liquid sample for the presence of a specific living biological entity, the method comprising: preparing a plurality of culture vessels each for selective detection of the presence of a different living biological entity, wherein preparing a said culture vessel comprises: providing a culture vessel comprising a sealable chamber for receiving and culturing a liquid sample such that presence of said biological entity is detectable by detecting a change in pressure in a head space of said chamber;providing a selective growth medium in said culture vessel, wherein said selective growth medium is in a dry form and selectively facilitates growth of a specific living biological entity, and providing the culture vessel with an identifier to identity said specific biological entity;providing a test system comprising a device to receive said culture vessel and to detect said change in pressure in said head space of said chamber, the device further comprising a temperature control system, and a data processor to monitor said detected change in pressure, to control said temperature control system to regulate a temperature of a liquid sample in said culture vessel, and to signal detection of the presence of a biological entity in said culture vessel from said detected change in pressure;storing a plurality of entity- selective test protocols in a memory of said test system,wherein a said test protocol defines one or both of a temperature of incubation of said liquid sample in said culture vessel and a threshold change in pressure in said head space of said chamber for detection of the target entity, wherein said test protocols are respectively identified according to one of a plurality of specific biological entities for which they selectively facilitate growth;selecting,from said plurality of culture vessels, a culture vessel to selectively detect a target said specific biological entity;providing a test liquid sample to said chamber of said selected culture vessel;using the identifier on said elected culture vessel to select a corresponding test protocol for said target specific biological entity; and running said selected test protocol on said test system to incubate said test liquid sample according to said test protocol to determine whether said target specific biological entity is present within said test liquid sample;wherein said determination comprises selection dependent upon both said selective growth medium and said entity-selective test protocol.
摘要翻译：我们描述了选择性测试液体样品以存在特定活体生物实体的方法，所述方法包括：制备多个培养容器，每个培养容器用于选择性检测不同活体生物体的存在，其中制备所述培养容器包括：提供包含用于接收和培养液体样品的可密封室的培养容器，使得可以通过检测所述室的顶部空间中的压力变化来检测所述生物实体的存在;在所述培养容器中提供选择性生长培养基，其中所述选择性生长培养基是干燥形式并且有选择地促进特定生物体实体的生长，以及为培养容器提供识别所述特定生物实体的标识符;提供测试系统，其包括接收所述培养容器的装置和检测所述室的所述顶部空间中的所述压力变化，所述装置进一步的提供温度控制系统，以及数据处理器，用于监视所述检测到的压力变化，以控制所述温度控制系统调节所述培养容器中的液体样品的温度，并且将所述生物实体的存在信号检测在所述培养容器从所述检测到的压力变化;将多个实体选择性测试方案存储在所述测试系统的存储器中，其中所述测试方案定义所述培养容器中所述液体样品的温育温度和用于检测目标实体的所述室的所述顶部空间中的压力的阈值变化，其中所述测试方案分别根据多个特定生物实体中的一个来选择性地促进生长;从所述多个培养容器中选择，用于选择性地检测所述特定生物实体的培养容器;向所述室提供测试液体样品的所述选择的培养容器;使用所述选择的培养容器上的标识符选择所述靶特异性生物实体的相应测试方案; 以及在所述测试系统上运行所述选定的测试方案，以根据所述测试方案孵育所述测试液体样品，以确定所述靶特异性生物实体是否存在于所述测试液体样品内;其中所述测定包括依赖于所述选择性生长培养基和说实体选择性测试协议。

2. 发明申请

WO2018037242A1 METHODS AND SYSTEM FOR MONITORING BALLAST WATER 审中-公开
标题翻译：用于监测压载水的方法和系统
公开(公告)号：WO2018037242A1
公开(公告)日：2018-03-01
申请号：PCT/GB2017/052506
申请日：2017-08-25
申请人： BACTEST LIMITED
发明人： PRICE, Derek , RICKETT, Toby William
IPC分类号： C12Q1/02 , C12Q1/04 , C12M1/34
CPC分类号： C12Q1/025 , B63J4/002 , C12Q1/04 , G01N33/1826
摘要： We describe a ballast water test system, the system comprising: at least one microbe detector to test a sample of ballast water for the presence of microbes and to produce microbe detector data representing a detected level of microbes in said sample; a plankton detector to test said sample of ballast water for the presence of plankton and to produce plankton data representing a detected level of plankton in said sample; a biocide detector to test said sample of ballast water for the presence of biocide and to produce biocide data representing a detected level of biocide in said sample; and a compliance determination system comprising: at least one input to receive said microbe detector data, said plankton data, and said biocide data, at least one output to provide sample compliance data, and a processor coupled to said at least one input, to said output and to working memory and to program memory, and wherein said program memory stores processor control code to: input said microbe detector data, said plankton data, and said biocide data; process said microbe detector data, said plankton data, and said biocide data to compare said microbe detector data, said plankton data, and said biocide data with a set of rules defining permitted levels of microbes, plankton and biocide in said sample of ballast water for compliance with a standard; and output standard compliance data defining whether said sample of ballast water is in compliance with said standard; wherein said compliance determination system further comprises an anti-fraud system to control user fraud to inhibit a user from fraudulently producing a result indicating that said sample of ballast water is falsely in compliance with said standard.
摘要翻译：我们描述了一种压载水测试系统，该系统包括：至少一个微生物检测器，用于测试压载水的样本中是否存在微生物并产生代表微生物检测水平的微生物检测器数据所述样品; 浮游生物检测器，用于测试所述压舱水样品中浮游生物的存在并产生表示所述样品中检测到的浮游生物水平的浮游生物数据; 生物杀灭剂检测器，用于测试所述压舱水样品中是否存在杀生物剂并产生表示所述样品中检测到的杀生物剂水平的杀生物剂数据; 以及顺从性确定系统，其包括：接收所述微生物检测器数据，所述浮游生物数据和所述生物杀灭剂数据的至少一个输入，用于提供样品依从性数据的至少一个输出，以及耦合到所述至少一个输入的处理器，输出和工作存储器并编程存储器，并且其中所述程序存储器存储处理器控制代码以：输入所述微生物检测器数据，所述浮游生物数据和所述杀生物剂数据; 处理所述微生物检测器数据，所述浮游生物数据和所述杀生物剂数据以将所述微生物检测器数据，所述浮游生物数据和所述杀生物剂数据与一组规则相比较，所述规则定义所述压舱水样品中微生物，浮游生物和杀生物剂的允许水平，符合标准; 并输出标准符合性数据，所述标准符合性数据定义所述压载水样品是否符合所述标准; 其中所述顺从性确定系统进一步包括反欺诈系统以控制用户欺诈，以禁止用户欺骗性地产生指示所述压舱水样品错误地符合所述标准的结果。

3. 发明申请

WO2014027183A1 METHOD AND INSTALLATION FOR WASTEWATER PROCESS MONITORING AND CONTROL 审中-公开
标题翻译：废水处理监测与控制方法与安装
公开(公告)号：WO2014027183A1
公开(公告)日：2014-02-20
申请号：PCT/GB2013/052133
申请日：2013-08-08
申请人： BACTEST LIMITED
发明人： PRICE, Derek , BROOKING, Annie
IPC分类号： C02F3/00 , C02F3/12 , C02F101/10 , C02F101/16
CPC分类号： C02F3/006 , C02F3/12 , C02F3/1221 , C02F2101/105 , C02F2101/16 , C02F2203/002 , C02F2209/001 , C02F2209/005 , C02F2209/03 , C12M41/36 , C12M41/40 , G01L9/00 , G01N33/1806 , Y02W10/15
摘要： We describe a method of closed-loop control of a waste water treatment plant, the method comprising: obtaining a fluid sample from a fluid of said plant; providing said fluid sample to a sealed chamber such that said fluid sample incompletely fills said sealed chamber leaving a headspace; incubating said fluid sample in said sealed chamber; determining a change in pressure in said headspace during said incubating; and controlling a degree of aeration of said waste water treatment plant responsive to said change in pressure. We also describe a method of measuring one or both of the food content and the biomass content of a fluid of a waste water treatment plant, the method comprising determining a value for one or both of food content and biomass content from a change in pressure.
摘要翻译：我们描述了废水处理厂的闭环控制方法，该方法包括：从所述设备的流体获得流体样品; 将所述流体样品提供到密封室，使得所述流体样品不完全填充所述密封室，留下顶部空间; 在所述密封室中孵育所述流体样品; 在所述孵育期间确定所述顶部空间中的压力变化; 以及响应于所述压力变化来控制所述废水处理设备的通风程度。我们还描述了一种测量废水处理设备的流体的食物含量和生物质含量之一或两者的方法，所述方法包括从压力变化确定食物含量和生物质含量中的一种或两种的值。

4. 发明申请

WO2017098244A1 METHOD OF DETERMINING THE EFFICACY OF A MICROBIAL DECONTAMINATION PROCESS 审中-公开
标题翻译：确定微生物净化过程效率的方法
公开(公告)号：WO2017098244A1
公开(公告)日：2017-06-15
申请号：PCT/GB2016/053859
申请日：2016-12-08
申请人： BACTEST LIMITED
发明人： PRICE, Derek
IPC分类号： C12Q1/22
CPC分类号： C12Q1/22
摘要： A method of and system for determining the efficacy of a microbial decontamination process are discussed. The method provides a determination of efficacy of the decontamination process by monitoring relative changes in the time to detect a threshold event (indicative of microbial growth) in samples taken from the input and output of the decontamination process. If the decontamination process is working, the time taken to detect a threshold event in the output sample will be greater than the time taken to detect a threshold event in the input sample. By comparing the time taken to detect the threshold events when system is calibrated to the input sample (since the composition of the input samples will vary), the level of decontamination of the decontamination process may be estimated, giving the user an estimated measure of the level of logarithmic kills (representing a logarithmic reduction in the number of viable microbes) by the decontamination process. The calibration is performed using the input sample, and one or more dilutions of the input sample.
摘要翻译：讨论了用于确定微生物净化过程的功效的方法和系统。该方法通过监测时间的相对变化来检测净化过程的功效，以检测从净化过程的输入和输出中取得的样本中的阈值事件（指示微生物生长）。如果净化过程正在进行，输出样本中检测阈值事件所花费的时间将大于检测输入样本中阈值事件所花费的时间。通过比较当系统校准到输入样本时检测阈值事件所花费的时间（因为输入样本的组成会变化），可以估计净化过程的净化水平，给用户估计通过净化过程的对数杀死水平（代表对数生存微生物的对数减少）。使用输入样本以及输入样本的一个或多个稀释度来执行校准。

5. 发明申请

WO2018134560A1 WASTEWATER TREATMENT PLANT CONTROL SYSTEMS 审中-公开
公开(公告)号：WO2018134560A1
公开(公告)日：2018-07-26
申请号：PCT/GB2018/050040
申请日：2018-01-09
申请人： BACTEST LIMITED
发明人： PRICE, Derek , EDWARD TAYLOR, Raymond
IPC分类号： C02F1/52 , C02F3/12 , C02F3/30 , C02F101/10 , C02F1/56
摘要： We describe a method of controlling the operation of a wastewater treatment plant, the method comprising: chemically dosing a first flow in said plant with one or more settlement enhancing chemicals; making a measurement of a second flow, wherein said measurement is dependent on a biochemical oxygen demand of said second flow, wherein said second flow is downstream of said first flow, and wherein said second flow comprises a mixture of a flow from an input to said plant and an RAS (returned activated sludge) flow of said plant; and using said measurement to control a level of said dosing of said one or more settlement enhancing chemicals.

6. 发明申请

WO2016051176A2 SENSING METHODS AND SYSTEMS 审中-公开
标题翻译：感测方法和系统
公开(公告)号：WO2016051176A2
公开(公告)日：2016-04-07
申请号：PCT/GB2015/052862
申请日：2015-09-30
申请人： BACTEST LIMITED
发明人： PRICE, Derek , RICKETT, Toby William
IPC分类号： G01N33/18
CPC分类号： C02F3/006 , C02F3/12 , C02F2209/15 , C02F2209/16 , C02F2209/18 , C02F2209/36 , C12M41/36 , G01N27/22 , G01N33/1806 , G01N33/1866
摘要： We describe a method of determining a food-to-biomass ratio in an aqueous fluid the method comprising: providing an aqueous fluid comprising viable biomass and food for said biomass, and wherein there is insufficient available food to sustain all said viable biomass; using a sensor (for example a respirometer or a sensor for sensing an amount of ammonia, ammonium, nitrates or nitrites) to determine an amount of food in said aqueous fluid available to said biomass; determining a measure of viable biomass in said aqueous fluid by measuring polarisability of viable biomass cells in an AC electric field; and determining a food-to-biomass ratio from said amount of food and said measure of viable biomass.
摘要翻译：我们描述了一种在含水流体中测定食物与生物质之比的方法，该方法包括：提供包含活的生物质和所述生物质的食物的水性流体，并且其中没有足够的可用食物来维持所有所述活的生物量; 使用传感器（例如用于感测一定量的氨，铵，硝酸盐或亚硝酸盐的呼吸计或传感器）来确定所述生物质可用的所述水性流体中的食物量; 通过测量AC电场中活的生物质细胞的极化度来确定所述含水流体中的活生物量的量度; 以及从所述食物量和所述活生物量的量测定食物与生物量之比。

7. 发明申请

WO2015019083A1 RESPIROMETER 审中-公开
标题翻译：呼吸
公开(公告)号：WO2015019083A1
公开(公告)日：2015-02-12
申请号：PCT/GB2014/052406
申请日：2014-08-06
申请人： BACTEST LIMITED
发明人： BROOKING, Annie , PRICE, Derek
IPC分类号： G01N33/18
CPC分类号： G01N33/18 , G01N33/1806 , G01N33/1886
摘要： We describe a floating respirometer,in particular for monitoring an activated sludge vessel of a sewage treatment plant. The device comprises: a buoyancy device to allow the respirometer to float in an aqueous liquid;a respirometer chamber, supported by the buoyancy device and arranged such that, when the respirometer is floating in said aqueous liquid, said chamber is partially filled with said aqueous liquid and defines an enclosed head space above said aqueous liquid; and a gas sensor in gaseous communication with said head space.
摘要翻译：我们描述一种浮动呼吸计，特别是用于监测污水处理厂的活性污泥容器。所述装置包括：浮力装置，其允许所述呼吸仪漂浮在水性液体中;呼吸仪室，由所述浮力装置支撑并且布置成使得当所述呼吸计器在所述水性液体中漂浮时，所述室部分地填充有所述水溶液液体并限定所述水性液体之上的封闭的顶部空间; 以及与所述顶部空间气体连通的气体传感器。

8. 发明申请

WO2014029976A1 EFFLUENT MONITORING SYSTEMS 审中-公开
标题翻译：低效监测系统
公开(公告)号：WO2014029976A1
公开(公告)日：2014-02-27
申请号：PCT/GB2013/052178
申请日：2013-08-16
申请人： BACTEST LIMITED
发明人： PRICE, Derek
IPC分类号： G01N33/18
CPC分类号： C12M41/40 , B01L1/00 , C02F3/006 , C02F3/02 , C02F3/341 , C02F2209/003 , C02F2209/008 , C02F2209/02 , C02F2209/03 , C02F2209/08 , C12M23/28 , C12M23/38 , G01N33/1806 , G01N33/1866 , Y02W10/15
摘要： We describe a system for monitoring effluent discharge to determine one or both of a biochemical oxygen demand (BOD) and a toxicity of the discharge. The system comprises: a culture vessel comprising a sealable chamber for culturing a fluid sample and a pressure measurement transducer for measuring a pressure in a headspace of the chamber; and a data processing system to: input pressure data from the pressure measurement transducer; and determine a value for one or both of BOD and toxicity from the change in pressure measured by the pressure transducer.
摘要翻译：我们描述了一种用于监测污水排放的系统，以确定生化需氧量（BOD）和排放物的毒性之一或两者。该系统包括：培养容器，其包括用于培养流体样品的可密封室和用于测量室的顶部空间中的压力的压力测量传感器; 以及数据处理系统，用于：从所述压力测量换能器输入压力数据; 并从压力传感器测量的压力变化中确定BOD和毒性中的一种或两种的值。

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