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1. 发明申请

WO2005080397A2 FUSED HETEROCYCLIC COMPOUNDS AND THEIR USE AS METABOTROPIC GLUTAMATE RECEPTOR ANTAGONISTS 审中-公开
标题翻译：融合杂环化合物及其作为代谢谷氨酸受体拮抗剂的用途
公开(公告)号：WO2005080397A2
公开(公告)日：2005-09-01
申请号：PCT/US2005005218
申请日：2005-02-17
申请人： ASTRAZENECA AB , NPS PHARMA INC , JOHANSSON MARTIN , WENSBO DAVID , MINIDIS ALEXANDER , STAAF KARIN , KERS ANNIKA , EDWARDS LOUISE , ISAAC METHVIN , STEFANAC TOMISLAV , SLASSI ABDELMALIK , MCLEOD DONALD
发明人： JOHANSSON MARTIN , WENSBO DAVID , MINIDIS ALEXANDER , STAAF KARIN , KERS ANNIKA , EDWARDS LOUISE , ISAAC METHVIN , STEFANAC TOMISLAV , SLASSI ABDELMALIK , MCLEOD DONALD
IPC分类号： A61K31/4188 , A61P1/00 , C07D487/00 , C07D487/04
CPC分类号： C07D487/04 , C07D513/04
摘要： The present invention is directed to compounds of formula (I): Wherein X , X , X , X , X , X , X , X , X , X , R , R , R , R , and n are as defined for formula I in the description. The invention also relates to processes for the preparation of the compounds and to new intermediates employed in the preparation pharmaceutical compositions containing the compounds, and to the use of the compounds in therapy.
摘要翻译：本发明涉及式（I）化合物：其中X 1，X 2，X 3，X 4，X 5，X 6，X 7，X X 9，X 10，R 1，R 2，R 3，R 4和n如在说明书中对式I所定义。本发明还涉及制备化合物的方法和用于制备含有化合物的药物组合物中所用的新中间体，以及该化合物在治疗中的用途。

2. 发明申请

WO2005080397A8 Fused hetrocyclic compounds and their use as metabotropic receptor antagonists for the treatment of gastrointestinal disorders 审中-公开
标题翻译：融合的hetrocyclic化合物及其作为代谢型受体拮抗剂用于治疗胃肠道疾病的用途
公开(公告)号：WO2005080397A8
公开(公告)日：2006-06-22
申请号：PCT/US2005005218
申请日：2005-02-17
申请人： ASTRAZENECA AB , NPS PHARMA INC , JOHANSSON MARTIN , WENSBO DAVID , MINIDIS ALEXANDER , STAAF KARIN , KERS ANNIKA , EDWARDS LOUISE , ISAAC METHVIN , STEFANAC TOMISLAV , SLASSI ABDELMALIK , MCLEOD DONALD , XIN TAO
发明人： JOHANSSON MARTIN , WENSBO DAVID , MINIDIS ALEXANDER , STAAF KARIN , KERS ANNIKA , EDWARDS LOUISE , ISAAC METHVIN , STEFANAC TOMISLAV , SLASSI ABDELMALIK , MCLEOD DONALD , XIN TAO
IPC分类号： C07D487/00 , A61K31/4188 , A61P1/00 , C07D487/04
CPC分类号： C07D487/04 , C07D513/04
摘要： The present invention is directed to compounds of formula: (I); wherein X 1 , X 2 , X 3 , X 4 , X 5 , X 6 , X 7 , X 8 , X 9 , X 10 , R 1 , R 2 , R 3 , R 4 , and n are as defined for formula I in the description. The invention also relates to processes for the preparation of the compounds and to new intermediates employed in the preparation, pharmaceutical compositions containing the compounds, and to the use of the compounds for treating gastrointestinal disorders.
摘要翻译：本发明涉及式（I）的化合物：其中X 1，X 2，X 3，X 4，X 5，，X 6，X 7，X 8，X 9，X 10， R 1，R 2，R 3，R 4，和n如式I中所定义，其中R 1，R 2，R 3，R 4，说明。本发明还涉及制备化合物的方法和用于制备中的新中间体，含有该化合物的药物组合物以及该化合物用于治疗胃肠道疾病的用途。

3. 发明申请

WO2004014881B1 "1,2,4"OXADIAZOLES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTOR-5 审中-公开
标题翻译： “1,2,4”恶二唑作为代谢型谷氨酸受体-5调节剂
公开(公告)号：WO2004014881B1
公开(公告)日：2004-07-15
申请号：PCT/US0324846
申请日：2003-08-08
申请人： ASTRAZENECA AB , NPS PHARMA INC , WENSBO DAVID , XIN TAO , STEFANAC TOMISLAV , ARORA JALAJ , EDWARDS LOUISE , ISAAC METHVIN , SLASSI ABDELMALIK , STORMANN THOMAS M , MCLEOD DONALD A , KERS ANNIKA , MALMBERG JOHAN , OSCARSSON KARIN , GYBACK HELENA , JOHANSSON MARTIN , MINIDIS ALEXANDER , WALDMAN MANGUS , YNGVE ULRIKA , OSTERWALL CHRISTOFFER
发明人： WENSBO DAVID , XIN TAO , STEFANAC TOMISLAV , ARORA JALAJ , EDWARDS LOUISE , ISAAC METHVIN , SLASSI ABDELMALIK , STORMANN THOMAS M , MCLEOD DONALD A , KERS ANNIKA , MALMBERG JOHAN , OSCARSSON KARIN , GYBACK HELENA , JOHANSSON MARTIN , MINIDIS ALEXANDER , WALDMAN MANGUS , YNGVE ULRIKA , OSTERWALL CHRISTOFFER
IPC分类号： C07D413/12 , A61K31/4245 , A61P25/00 , C07D271/00 , C07D413/14 , C07D417/14
CPC分类号： C07D413/14 , C07D413/12 , C07D417/14
摘要： The present invention relates to new compounds of formula (I), a process for their preparation and new intermediates prepared therein, pharmaceutical formulations containing said compounds and to the use of said compounds in therapy. In particular, there are compounds according to the present invention that are potent and selective for the mGluR Group I receptor and more particularly for mGluR5. Thus, it is expected that the compounds of the invention are well suited for the prevention and/or treatment of mGluR5 receptor-mediated disorders such as acute and chronic neurological and psychiatric disorders and chronic and acute pain disorders.
摘要翻译：本发明涉及式（I）的新化合物，其制备方法和其中制备的新中间体，含有所述化合物的药物制剂以及所述化合物在治疗中的用途。具体而言，本发明的化合物对mGluR组I受体，特别是对mGluR5有效且具有选择性。因此，预期本发明的化合物非常适用于预防和/或治疗mGluR5受体介导的疾病，例如急性和慢性神经和精神疾病以及慢性和急性疼痛疾病。

4. 发明申请

WO2004014881A2 NEW COMPOUNDS 审中-公开
标题翻译：新化合物
公开(公告)号：WO2004014881A2
公开(公告)日：2004-02-19
申请号：PCT/US0324846
申请日：2003-08-08
申请人： ASTRAZENECA AB , NPS PHARMA INC , WENSBO DAVID , XIN TAO , STEFANAC TOMISLAV , ARORA JALAJ , EDWARDS LOUISE , ISAAC METHVIN , SLASSI ABDELMALIK , STORMANN THOMAS M , MCLEOD DONALD A , KERS ANNIKA , MALMBERG JOHAN , OSCARSSON KARIN , GYBACK HELENA , JOHANSSON MARTIN , MINIDIS ALEXANDER , WALDMAN MANGUS , YNGVE ULRIKA , OSTERWALL CHRISTOFFER
发明人： WENSBO DAVID , XIN TAO , STEFANAC TOMISLAV , ARORA JALAJ , EDWARDS LOUISE , ISAAC METHVIN , SLASSI ABDELMALIK , STORMANN THOMAS M , MCLEOD DONALD A , KERS ANNIKA , MALMBERG JOHAN , OSCARSSON KARIN , GYBACK HELENA , JOHANSSON MARTIN , MINIDIS ALEXANDER , WALDMAN MANGUS , YNGVE ULRIKA , OSTERWALL CHRISTOFFER
IPC分类号： C07D413/12 , A61K31/4245 , A61P25/00 , C07D271/00 , C07D413/14 , C07D417/14
CPC分类号： C07D413/14 , C07D413/12 , C07D417/14
摘要： The present invention relates to new compounds of formula I, (I) a process for their preparation and new intermediates prepared therein, pharmaceutical formulations containing said compounds and to the use of said compounds in therapy.
摘要翻译：本发明涉及新的式I化合物，（I）其制备方法和其中制备的新中间体，含有所述化合物的药物制剂和所述化合物在治疗中的用途。

5. 发明申请

WO2005082884A2 NEW COMPOUNDS 审中-公开
标题翻译：新化合物
公开(公告)号：WO2005082884A2
公开(公告)日：2005-09-09
申请号：PCT/US2005004751
申请日：2005-02-15
申请人： ASTRAZENECA AB , NPS PHARMA INC , JOHANSSON MARTIN , MALMSTROEM JONAS , MINIDIS ALEXANDER , NILSSON KAROLINA , WENSBO DAVID , WAALLBERG ANDREAS , OESTERLUND KRISTER
发明人： JOHANSSON MARTIN , MALMSTROEM JONAS , MINIDIS ALEXANDER , NILSSON KAROLINA , WENSBO DAVID , WAALLBERG ANDREAS , OESTERLUND KRISTER
IPC分类号： A61K31/506 , C07D401/04 , C07D401/14 , C07D405/14 , C07D417/14
CPC分类号： C07D417/14 , C07D401/04 , C07D401/14 , C07D405/14
摘要： The present invention is directed to novel compounds, to a process for their preparation, their use in therapy and pharmaceutical compositions comprising the novel compounds.
摘要翻译：本发明涉及新化合物，其制备方法，其在治疗中的应用和包含新化合物的药物组合物。

6. 发明申请

WO2008048149A8 A TILT-DEPENDENT BEAM-SHAPE SYSTEM 审中-公开
标题翻译： TILT相关的BEAM形状系统
公开(公告)号：WO2008048149A8
公开(公告)日：2009-04-30
申请号：PCT/SE2006001170
申请日：2006-10-16
申请人： ERICSSON TELEFON AB L M , MANHOLM LARS , ANDERSSON MATS H , JOHANSSON MARTIN , PETERSSON SVEN OSCAR
发明人： MANHOLM LARS , ANDERSSON MATS H , JOHANSSON MARTIN , PETERSSON SVEN OSCAR
IPC分类号： H01Q3/30 , H04B1/18
CPC分类号： H01Q1/246 , H01Q3/30 , H01Q21/22
摘要： The present invention relates to a system for changing the radiation pattern shape of an antenna array 83; 88 during electrical tilting. The antenna array 83; 88 has multiple antenna elements 84, and the system comprises a phase- shifting device 10; 20; 40; 85 provided with a primary port 11 configured to receive a transmit signal, and multiple secondary ports 121- 124; 12 configured to provide phase shifted output signals to each antenna element 84. The system further comprises a phase-taper device 20; 40; 85; 87 that changes phase taper over the antenna elements, and thus the beam shape, with tilt angle ?. The invention is adapted for use in down-link as well as up-link within a wireless communication system.
摘要翻译：本发明涉及一种用于改变天线阵列83的辐射图形形状的系统; 88电气倾斜期间。天线阵列83; 88具有多个天线元件84，并且该系统包括相移装置10; 20; 40; 85设置有被配置为接收发射信号的主端口11和多个次级端口121- 124; 12被配置为向每个天线元件84提供相移输出信号。该系统还包括相位锥形装置20; 40; 85; 87改变天线元件上的相位锥度，从而改变波束形状，具有倾斜角θ。本发明适用于无线通信系统中的下行链路以及上行链路。

7. 发明申请

WO2010149944A1 INDOLYL-SUBSTITUTED PYRAZINO-QUINOLINES AND THEIR USE FOR THE TREATMENT OF CANCER 审中-公开
标题翻译：间接取代的吡嗪喹啉及其用于治疗癌症的用途
公开(公告)号：WO2010149944A1
公开(公告)日：2010-12-29
申请号：PCT/GB2010000514
申请日：2010-03-19
申请人： ONCOREL AB , PERSSON JENNY , LARSSON RIKARD , STERNER OLOV , JOHANSSON MARTIN
发明人： PERSSON JENNY , LARSSON RIKARD , STERNER OLOV , JOHANSSON MARTIN
IPC分类号： C07D471/04 , A61K31/4985 , A61P35/00 , C07D491/04
CPC分类号： A61K31/4985 , C07D471/04 , C07D471/14 , C07D491/14
摘要： There is provided compounds of formula I, wherein the wedged bonds, R1, R2, R3, R4, R5, R5a, R6, R7, R8, R9, R10, R11, R12, R13, R14, X and Y have meanings given in the description, and pharmaceutically- acceptable salts thereof, which compounds are useful in the treatment of cancer and conditions affected by inhibition of angiogenesis.
摘要翻译：提供式I化合物，其中楔形键，R1，R2，R3，R4，R5，R5a，R6，R7，R8，R9，R10，R11，R12，R13，R14，X和Y具有其描述和药学上可接受的盐，该化合物可用于治疗受血管生成抑制影响的癌症和病症。

8. 发明申请

WO2005043362A8 POWER SWITCH 审中-公开
标题翻译：开关;电源开关
公开(公告)号：WO2005043362A8
公开(公告)日：2005-07-07
申请号：PCT/DK2004000753
申请日：2004-10-29
申请人： INTERNAT POWER SWITCH , UZUNOVIC NIKOLA , JOHANSSON MARTIN , DAMGAARD ERIK , RISAGER MORTEN
发明人： UZUNOVIC NIKOLA , JOHANSSON MARTIN , DAMGAARD ERIK , RISAGER MORTEN
IPC分类号： G06F1/18 , G06F1/26 , H04L12/12 , H04L12/26 , H04L12/28
CPC分类号： H04L12/12 , G06F1/266 , G06F2200/261 , H04L12/2803 , H04L12/2825 , H04L12/2829 , H04L43/00 , H04L2012/285 , Y02D10/175 , Y02D50/40 , Y04S40/168
摘要： The present invention relates to a power switch, data system, interface and a data structure for controlling power outlets on one or more power switches. Each power switch comprises a sensor bus and watt meters in order to be able to monitor power consumption and environmental changes. Furthermore the power switches comprises a memory and a processor in order to be able to automatically control the power outlets without interference from a user terminal.
摘要翻译：本发明涉及用于控制一个或多个电源开关上的电源插座的电源开关，数据系统，接口和数据结构。每个电源开关包括传感器总线和瓦特表，以便能够监视功耗和环境变化。此外，功率开关包括存储器和处理器，以便能够自动控制电源插座而不受用户终端的干扰。

9. 发明申请

WO9959346A2 ARRANGEMENT TO INTERCONNECT USERS AND SERVICE PROVIDERS 审中-公开
标题翻译：连接用户和服务提供商的安排
公开(公告)号：WO9959346A2
公开(公告)日：1999-11-18
申请号：PCT/SE9900740
申请日：1999-05-04
申请人： TELIA AB , JOHANSSON MARTIN , JUSSILA KARI , BYSTROEM LEIF
发明人： JOHANSSON MARTIN , JUSSILA KARI , BYSTROEM LEIF
IPC分类号： H04L12/24 , H04L29/06 , H04L29/08 , H04Q11/04 , H04Q
CPC分类号： H04L41/00 , H04L29/06 , H04L67/14 , H04L69/24 , H04L69/329 , H04Q11/04
摘要： The invention relates to an arrangement to interconnect users and service providers to, independent of qualities of different carrier services or specific networks and access forms, transmit information between users and service providers. The invention provides an interface with specified qualities to respective interconnect the user and the service provider with a connectivity network which includes management system and the physical transmission equipment to transmit information between the user and the service provider. Preferably the interfaces are dynamically adaptive and have adaptive management qualities.
摘要翻译：本发明涉及一种使用户和服务提供商互连的装置，其独立于不同运营商服务或特定网络和接入形式的质量，在用户和服务提供商之间传输信息。本发明提供了一种具有指定质量的接口，以分别将用户和服务提供商与包括管理系统和物理传输设备的连接网络互连，以在用户和服务提供商之间传输信息。优选地，接口是动态自适应的并且具有适应性管理质量。

10. 发明申请

WO2012131351A3 PERCUTANEOUS IMPLANT AND OSTOMY METHOD 审中-公开
标题翻译： PERCUTANEOUS IMPLANT和OSTOMY方法
公开(公告)号：WO2012131351A3
公开(公告)日：2013-01-24
申请号：PCT/GB2012050668
申请日：2012-03-26
申请人： OSTOMYCURE AS , JOHANSSON MARTIN , AXELSSON ROBERT , AXELSSON JAN ERIK , JACKSON ROBERT
发明人： JOHANSSON MARTIN , AXELSSON ROBERT , AXELSSON JAN ERIK
IPC分类号： A61F5/445
CPC分类号： A61F5/445 , A61F2005/4455
摘要： A percutaneous ostomy implant for implantation into the abdominal wall of a patient comprises: a connecting member for mounting an external detachable device thereto; a first tubular ingrowth member depending from the connecting member; and a second tubular ingrowth member depending from the connecting member and being radially outwardly spaced from the first tubular ingrowth member. The first tubular ingrowth member is adapted to receive a bowel segment within it to form a stoma and serosal tissue of that bowel segment may infiltrate the first tubular ingrowth member. The second tubular member is adapted to abut dermal tissue such that the dermal tissue may infiltrate the second tubular ingrowth member, thereby securing and sealing the ostomy implant to the dermis.
摘要翻译：用于植入患者腹壁的经皮造口植入物包括：用于将外部可拆卸装置安装到其上的连接构件; 第一管状向内生长构件，其从所述连接构件悬垂; 以及第二管状向内生长构件，其从连接构件悬垂并且与第一管状向内生长构件径向向外间隔开。第一管状向内生长构件适于在其内接收肠段以形成造口，并且该肠段的浆膜组织可渗透第一管状向内生长部件。第二管状构件适于邻接真皮组织，使得真皮组织可以渗透第二管状向内生长构件，从而将造口植入物固定并密封到真皮层。

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