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1. 发明申请

WO2013055859A1 METAL-ASSISTED AND MICROWAVE-ACCELERATED EVAPORATIVE CRYSTALLIZATION 审中-公开
标题翻译：金属辅助和微波加速蒸发结晶
公开(公告)号：WO2013055859A1
公开(公告)日：2013-04-18
申请号：PCT/US2012/059660
申请日：2012-10-11
申请人： ASLAN, Kadir
发明人： ASLAN, Kadir
IPC分类号： C07C227/00
CPC分类号： C07H1/06 , C07B2200/13 , C07C227/42 , C30B7/005 , C30B28/06 , C30B29/58 , C07C229/08
摘要： The present invention relates to methods for rapid crystallization of amino acids, drug molecules, proteins and DNA/peptides. One method for rapid crystallization of functional group-containing molecules selected from the group consisting of amino acids, drug molecules, proteins and DNA/peptides includes (A) providing at least one metal or metal oxide in particulate or thin film form to provide (a) selective nucleation sites for crystallization of the functional group-containing molecules due to interactions of their functional groups and metal surfaces or engineered metal surfaces and (b) a microwave-transparent medium to create a thermal gradient between the metal surfaces or engineered metal surfaces and a warmer solution containing functional group-containing molecules to be crystallized, and (B) conducting microwave heating to cause the functional group-containing molecules to be crystallized.
摘要翻译：本发明涉及氨基酸，药物分子，蛋白质和DNA /肽快速结晶的方法。选自氨基酸，药物分子，蛋白质和DNA /肽的含官能团分子的快速结晶的一种方法包括（A）提供至少一种颗粒或薄膜形式的金属或金属氧化物以提供（a ）由于其官能团和金属表面或工程金属表面的相互作用而使含官能团的分子结晶的选择性成核位点和（b）微波透明介质以在金属表面或工程金属表面之间产生热梯度，以及含有待结晶的含有官能团的分子的较暖的溶液，（B）进行微波加热使含官能团的分子结晶。

2. 发明申请

WO2006052548A1 METAL-ENHANCED FLUORESCENCE FROM PLASTIC SUBSTRATES 审中-公开
标题翻译：金属增强塑料基体的荧光
公开(公告)号：WO2006052548A1
公开(公告)日：2006-05-18
申请号：PCT/US2005/039498
申请日：2005-10-28
申请人： UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE , GEDDES, Chris, D. , ASLAN, Kadir
发明人： GEDDES, Chris, D. , ASLAN, Kadir
IPC分类号： B05D1/38 , B05D3/06 , B05D3/10 , B05D5/06 , B32B9/04 , B32B27/32 , B32B27/34 , B32B27/36 , G01N21/76
CPC分类号： C23C18/1601 , B05D3/101 , B05D5/067 , B05D7/02 , B82Y30/00 , C08J7/04 , C08J2369/00 , C23C18/2006 , C23C18/22 , C23C18/30 , C23C18/44 , G01N21/6428 , G01N21/648 , Y10T428/254
摘要： The present invention relates to methods for functionally modifying a polymeric surface for subsequent deposition of mettalic particles and/or films, wherein the polymeric surface is modified by increasing hydroxyl and/or amine functional groups thereby providing an activated polymeric surface for deposition of metallic particles to form a fluorescence sensing device. The device can be used for metal-enhanced fluorescence of fluorophores positioned above the metallic particles that can be readily applied to diagnostic or sensing applicantions of metal-enhanced fluorescence.
摘要翻译：本发明涉及用于功能性改性聚合物表面以随后沉积太阳颗粒和/或膜的方法，其中通过增加羟基和/或胺官能团来改性聚合物表面，从而提供用于沉积金属颗粒的活化聚合物表面形成荧光感测装置。该装置可用于位于金属颗粒上方的荧光团的金属增强荧光，其可以容易地应用于金属增强荧光的诊断或感测申请。

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