会员体验
专利管家(专利管理)
工作空间(专利管理)
风险监控(情报监控)
数据分析(专利分析)
侵权分析(诉讼无效)
联系我们
交流群
官方交流:
QQ群: 891211   
微信请扫码    >>>
现在联系顾问~
热词
    • 6. 发明申请
    • A NOVEL NEOSPORA CANINUM VACCINE
    • 一个新的NEOSPORA CANINUM VACCINE
    • WO2009105355A3
    • 2009-10-22
    • PCT/US2009033437
    • 2009-02-06
    • US AGRICULTURETUO WENBINJENKINS MARK CZHAO YAN
    • TUO WENBINJENKINS MARK CZHAO YAN
    • A61K39/002A61K48/00A61P33/02A61P37/04
    • A61K39/002A61K2039/545A61K2039/552A61K2039/55561A61K2039/55566
    • Neospora caninum is the causal agent of bovine neosporosis which results in high levels of abortion. The present study determined the protective efficacy of two Neospora antigens- Neospora cyclophilin (NcCyP) and NcSRS2. The ability of native NcCyP to upregulate mouse IFN? was also confirmed in this study. Recombinant NcCyP or NcSRS2 were tested either alone or in combination and formulated with adjuvant ImmuMax-SR and CpG. Female BALB/c mice (n=15) of 10-12 weeks of age were immunized s.c. twice in a 2-week interval with vaccines containing either NcCyP alone, NcSRS2 alone, NcCyP plus NcSRS2, or non-recombinant bacterial antigen (NR) in 2 separate trials. All mice were challenge-infected 3 weeks following the booster immunization and necropsied 3 weeks after the challenge infection. Brain and serum were collected and Nc-specific DNA sequence in brain tissue and antibodies in serum were analyzed by PCR or ELISA/Westem blotting. Results showed that mice vaccinated with rNcCyP, rNcSRS2, or both rNcCyP and rNcSRS2 responded with high levels of NcCyP or NcSRS2 specific antibodies. Overall, mice received vaccines formulated with either rNcCyP or rNcCyP and rNcSRS2 had a higher (p
    • 新孢子虫是牛新孢子虫病的致病因子,导致高水平的流产。 本研究确定了两种新孢子虫抗原 - 新孢子虫亲环蛋白(NcCyP)和NcSRS2的保护功效。 天然NcCyP上调小鼠IFN的能力 在本研究中也得到证实。 单独或组合测试重组NcCyP或NcSRS2,并用佐剂ImmuMax-SR和CpG配制。 10-12周龄的雌性BALB / c小鼠(n = 15)免疫s.c. 在两个单独的试验中,在含有单独的NcCyP,单独的NcSRS2,NcCyP加NcSRS2或非重组细菌抗原(NR)的疫苗的两周间隔中两次。 所有小鼠在加强免疫后3周进行攻击感染,并在攻击感染后3周进行尸检。 收集脑和血清,通过PCR或ELISA / Western印迹分析血清中脑组织和抗体中的Nc特异性DNA序列。 结果表明,用rNcCyP,rNcSRS2或rNcCyP和rNcSRS2两者接种的小鼠均响应高水平的NcCyP或NcSRS2特异性抗体。 总体而言,小鼠接受用rNcCyP或rNcCyP配制的疫苗,当与模拟或未接种疫苗的小鼠相比时,rNcSRS2具有较高的(p <0.01)的保护。 单独使用rNcSRS2免疫的组表现出略低的保护水平,比未接种组更高(p <0.05),但与模拟接种组相比没有差异(p = 0.06)。 本研究的结果表明,NcCyP是一种非常有效的候选疫苗,可用于防止新孢子虫感染。
    • 8. 发明申请
    • METHOD OF OPTIMIZING RADIO LINK MONITOR WINDOW PARAMETER IN WIRELESS HETEROGENEOUS COMMUNICATION NETWORK
    • 无线异构通信网络优化无线链路监控窗口参数的方法
    • WO2014030065A3
    • 2014-05-15
    • PCT/IB2013002236
    • 2013-08-19
    • ALCATEL LUCENT
    • SUN HUANZHAO YANSUN FANGLEI
    • H04B7/02H04B7/06H04B17/00
    • H04B7/024H04B7/0632H04B17/12
    • The invention relates to a method, in a first base station (110) of a wireless communication network, of calibrating an offset of an antenna array of the first base station relative to an antenna array of a second base station (120) in the wireless communication network, the method including the steps of: dividing a whole parameter offset range into a plurality of segments (S211) according to the requirement of calibration precision and assigning a feature value for each segment; compensating uplink channel state information according to the feature value assigned to one of the plurality of segments in a predetermined order in a first cycle (S411); designing a pre-coding vector or matrix for downlink data transmission according to a compensation result (S413), pre-coding downlink data and subsequently transmitting the downlink data to a user equipment cooperatively with the second base station (S414, S423); and judging whether all the segments of the parameter offset range have been traversed (S415), and if a judgment result is negative, then repeating the foregoing steps; or if the judgment result is positive, then ending the first cycle (S415).
    • 本发明涉及一种在无线通信网络的第一基站(110)中相对于无线网络中的第二基站(120)的天线阵列校准第一基站的天线阵列的偏移的方法, 通信网络,该方法包括以下步骤:根据校准精度的要求将整个参数偏移范围划分为多个段(S211),并为每个段分配特征值; 根据在第一周期中以预定顺序分配给所述多个段中的一个段的特征值补偿上行链路信道状态信息(S411); 根据补偿结果设计用于下行链路数据传输的预编码向量或矩阵(S413),对下行链路数据进行预编码,随后与第二基站协作地将下行链路数据发送给用户设备(S414,S423); 并且判断参数偏移范围的所有段是否已经被遍历(S415),如果判断结果为否定,则重复上述步骤; 或者如果判断结果为正,则结束第一周期(S415)。