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    • 2. 发明申请
    • IMPRINTING OF SUPPORTED AND FREE-STANDING 3-D MICRO-OR NANO-STRUCTURES
    • 支持和自由置换三维微结构或纳米结构
    • WO2005113422A1
    • 2005-12-01
    • PCT/SG2005/000159
    • 2005-05-24
    • AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCHTHE REGENTS OF THE UNIVERSITY OF MICHIGANKONG, Yen PengLOW, Hong YeePANG, Stella, W.YEE, Albert, F.
    • KONG, Yen PengLOW, Hong YeePANG, Stella, W.YEE, Albert, F.
    • B81C1/00
    • A61M25/00B27N3/08B28B3/06B81C99/0085B81C2201/034B81C2203/032B81C2203/038B82Y10/00B82Y40/00G03F7/0002Y10T428/24479Y10T428/254
    • The present invention is directed to micro- and nano-scale imprinting methods and the use of such methods to fabricate supported and/or free-standing 3-D micro- and/or nano-structures of polymeric, ceramic, and/or metallic materials. In some embodiments, a duo-mold approach is employed in the fabrication of these structures. In such methods, surface treatments are employed to impart differential surface energies to different molds and/or different parts of the mold(s). Such surface treatments permit the formation of three-dimensional (3-D) structures through imprinting and the transfer of such structures to a substrate. In some or other embodiments, such surface treatments and variation in glass transition temperature of the polymers used can facilitate separation of the 3-D structures from the molds to form free-standing micro- and/or nano-structures individually and/or in a film. In some or other embodiments, a "latch-on" assembly technique is utilized to form supported and/or free-standing stacked micro- and/or nano-structures that enable the assembly of polymers without a glass transition temperature and eliminate the heating required to assemble thermoplastic polymers.
    • 本发明涉及微尺度和纳米级压印方法,并且使用这种方法来制造聚合物,陶瓷和/或金属材料的负载和/或独立的3-D微观和/或纳米结构 。 在一些实施例中,在制造这些结构中采用双模方法。 在这种方法中,使用表面处理以将不同的表面能赋予模具的不同模具和/或模具的不同部件。 这种表面处理允许通过压印形成三维(3-D)结构并将这种结构转移到基底上。 在一些或其它实施方案中,所使用的聚合物的这种表面处理和玻璃化转变温度的变化可以促进3-D结构与模具的分离,以分别形成独立的和/或纳米结构, 电影。 在一些或其它实施方案中,使用“闭锁”组装技术来形成支撑和/或独立堆叠的微结构和/或纳米结构,其能够组装聚合物而不具有玻璃化转变温度并消除所需的加热 组装热塑性聚合物。
    • 6. 发明申请
    • LIQUID DELIVERING DEVICE
    • 液体输送装置
    • WO2003018089A1
    • 2003-03-06
    • PCT/SG2002/000180
    • 2002-08-07
    • INSTITUTE OF MATERIALS RESEARCH AND ENGINEERINGZHANG, Xuan, XiongXU, YuanKONG, Yen, PengYAO, KuiHE, Xu, Jiang
    • ZHANG, Xuan, XiongXU, YuanKONG, Yen, PengYAO, KuiHE, Xu, Jiang
    • A61M5/155
    • A61M5/145A61M5/1452A61M5/14586A61M5/1483A61M2005/14204
    • An electrochemically actuated liquid delivering device which is capable of releasing specific volumes of liquid at desired flow rates. The device includes a sealed electrolytic chamber which is adapted to contain an electrolyte and has at least one pair of electrodes which are at least partially in contact with the electrolyte. It also has a liquid chamber which is housed at least partially within the electrolytic chamber and is adapted to contain a liquid. It has pressure transfer means separating the electrolytic chamber from the liquid chamber and administering means which is adapted to release the liquid from the liquid chamber under the influence of pressure applied to the liquid chamber. The device is arranged so that when current is passed through the electrolyte via the electrodes, gas is generated from the electrolyte thereby increasing pressure inside the electrolytic chamber. That increase in pressure is transferred to the liquid chamber via the pressure transfer means and a determinable amount of the liquid is released from the liquid chamber via the administering means. The device has particular application in liquid drug delivery systems such as insulin infusion.
    • 一种电化学驱动的液体输送装置,其能够以期望的流速释放特定体积的液体。 该装置包括密封的电解室,其适于容纳电解质并且具有至少部分地与电解质接触的至少一对电极。 它还具有至少部分地容纳在电解室内并且适于容纳液体的液体室。 其具有将电解室与液体室分离的压力传递装置和适于在施加到液体室的压力的影响下从液体室释放液体的施用装置。 该装置被布置成使得当电流经由电极通过电解质时,从电解液产生气体,从而增加电解室内的压力。 压力的增加通过压力传递装置转移到液体室,并且通过给药装置从液体室释放出可确定量的液体。 该装置在诸如胰岛素输注的液体药物递送系统中具有特别的应用。
    • 9. 发明申请
    • METHODS OF CREATING PATTERNS ON SUBSTRATES AND ARTICLES OF MANUFACTURE RESULTING THEREFROM
    • 基板上形成图案的方法及其制造方法
    • WO2004107045A2
    • 2004-12-09
    • PCT/US2004016016
    • 2004-05-21
    • AGENCY SCIENCE TECH & RESUNIV MICHIGANBAO LIRONGTAN LIHUANG XUDONGKONG YEN PENGGUO LINGJIE JAYPANG STELLA WYEE ALBERT
    • BAO LIRONGTAN LIHUANG XUDONGKONG YEN PENGGUO LINGJIE JAYPANG STELLA WYEE ALBERT
    • B05D3/10B29C33/00B44C1/165B44C3/08C03C17/30G03F20060101G03F7/00G03F
    • G03F7/0002B82Y10/00B82Y30/00B82Y40/00
    • Methods of creating patterns on substrates are presented, and articles of manufacture resulting therefrom. One method comprises applying a first surface energy modifier (18) to an applicator (16) to form a coating on the applicator; contacting the coating (18) with a receiving member (4), the receiving member having a topography, the coating only contacting and remaining on at least some protrusions (8); exposing the first modified receiving member (22) to a second surface energy modifier (21), thereby forming a second modified receiving member (24) having surface modified recesses; applying a composition (26) comprising a polymeric material to the second modified receiving member (24), the composition substantially conforming to the topography of the surface modified protrusion's (8) and the surface modified recesses; and contacting the composition-coated, surface modified protrusions with a substrate (11) for a time and under conditions sufficient to transfer the polymeric material (26) on protrusions to the substrate (11). Because the surface energy of the sidewalls is lower than that on the protrusions, polymer dewetting from the sidewalls is promoted, which makes the polymer film discontinuous along the edges of patterns. Therefore, inked polymer patterns from the protrusions of the mold show very smooth edges and smaller dimensions compared to that of the mold.
    • 呈现在基板上形成图案的方法以及由此产生的制品。 一种方法包括将第一表面能量调节剂(18)施加到施用器(16)上以在施用器上形成涂层; 使所述涂层(18)与接收构件(4)接触,所述接收构件具有形貌,所述涂层仅接触并保留在至少一些突起(8)上; 将第一改进的接收构件(22)暴露于第二表面能量改性剂(21),从而形成具有表面改性凹槽的第二改进的接收构件(24); 将包含聚合物材料的组合物(26)施加到第二改性接收构件(24)上,该组合物基本上符合表面改性突起(8)和表面改性凹槽的形貌; 并且使组合物涂覆的表面改性的突起与衬底(11)接触足以将突起上的聚合物材料(26)转移到衬底(11)上的时间和条件。 由于侧壁的表面能低于突起上的表面能,因此促进了从侧壁的聚合物去湿,这使得聚合物膜沿着图案的边缘不连续。 因此,与模具相比,来自模具的凸起的上色聚合物图案显示出非常光滑的边缘和更小的尺寸。