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1. 发明申请

WO2005102647A3 COMPRESSION MOULDING MULTI-LAYERED CONTAINER-LIKE ARTICLES 审中-公开
标题翻译：压缩成型多层容器类似物品
公开(公告)号：WO2005102647A3
公开(公告)日：2006-03-09
申请号：PCT/US2005013332
申请日：2005-04-18
申请人： ADVANCED PLASTICS TECHNOLOGIES , HUTCHINSON GERALD , LEE ROBERT , FARHA SAID
发明人： HUTCHINSON GERALD , LEE ROBERT , FARHA SAID
IPC分类号： B29C43/14 , B29C43/20 , B29C43/34 , B29B11/12 , B29C43/08 , B29C43/18 , B29C43/42
CPC分类号： B29C43/146 , B29B11/08 , B29B11/14 , B29B2911/1402 , B29B2911/14026 , B29B2911/14033 , B29B2911/1404 , B29B2911/14053 , B29B2911/1406 , B29B2911/14066 , B29B2911/14073 , B29B2911/1408 , B29B2911/14093 , B29B2911/14106 , B29B2911/14113 , B29B2911/14126 , B29B2911/14133 , B29B2911/14213 , B29B2911/14233 , B29B2911/143 , B29B2911/14326 , B29B2911/14333 , B29B2911/14366 , B29B2911/14433 , B29B2911/1444 , B29B2911/1446 , B29B2911/14466 , B29B2911/1458 , B29B2911/14646 , B29C43/08 , B29C43/18 , B29C43/203 , B29C43/34 , B29C43/36 , B29C44/12 , B29C45/1646 , B29C47/0023 , B29C47/06 , B29C47/065 , B29C49/12 , B29C2043/046 , B29C2043/3433 , B29C2043/3444 , B29C2043/3623 , B29K2023/06 , B29K2023/0625 , B29K2023/083 , B29K2023/086 , B29K2023/12 , B29K2025/00 , B29K2027/06 , B29K2055/02 , B29K2067/00 , B29K2067/006 , B29K2069/00 , B29K2077/00 , B29K2105/04 , B29K2105/162 , B29K2105/258 , B29K2623/12 , B29K2995/0067 , B29K2995/0069 , B29L2009/005 , B29L2031/565 , B29L2031/7158
摘要： In preferred embodiments methods and apparatuses can produce articles that have formable material. The articles may be mono and multilayer. The articles can be formed by various methods.
摘要翻译：在优选实施例中，方法和装置可以产生具有可成形材料的制品。制品可以是单层和多层。物品可以通过各种方法形成。

2. 发明申请

WO2005102668A3 A BOTTLE, A METHOD OF FORMING THE BOTTLE, A LIQUID DISPENSING SYSTEM AND AN EXTRUDED PROFILE 审中-公开
标题翻译：瓶，成型方法，液体分配系统和挤压型材
公开(公告)号：WO2005102668A3
公开(公告)日：2005-12-29
申请号：PCT/US2005013150
申请日：2005-04-18
申请人： ADVANCED PLASTICS TECHNOLOGIES , HUTCHINSON GERALD , LEE ROBERT , FARHA SAID
发明人： HUTCHINSON GERALD , LEE ROBERT , FARHA SAID
IPC分类号： B29C45/16 , B29C49/04 , B29C49/06 , B29C49/22 , B65D1/02 , B65D23/08 , B67D1/00
CPC分类号： B29C49/22 , B29B2911/1402 , B29B2911/14026 , B29B2911/1404 , B29B2911/14053 , B29B2911/1406 , B29B2911/14066 , B29B2911/1408 , B29B2911/14093 , B29B2911/14106 , B29B2911/14113 , B29B2911/1412 , B29B2911/14126 , B29B2911/1424 , B29B2911/14246 , B29B2911/14253 , B29B2911/1426 , B29B2911/14266 , B29B2911/14273 , B29B2911/1428 , B29B2911/14646 , B29C44/04 , B29C45/1684 , B29C49/04 , B29C49/06 , B29C49/12 , B29C49/221 , B29C51/10 , B29C70/603 , B29C70/66 , B29C2049/0089 , B29C2049/225 , B29C2791/006 , B29K2023/083 , B29K2023/086 , B29K2023/12 , B29K2067/00 , B29K2105/0076 , B29K2105/04 , B29K2105/048 , B29K2105/162 , B29K2105/165 , B29K2105/253 , B29K2105/258 , B29K2105/26 , B29K2623/12 , B29K2995/0015 , B29K2995/0067 , B29L2009/00 , B29L2023/22 , B29L2031/463 , B29L2031/7158 , B29L2031/716 , B32B1/02 , B32B5/18 , B32B5/20 , B32B27/065 , B32B27/08 , B32B27/32 , B32B27/325 , B32B27/36 , B32B2266/025 , B32B2266/0264 , B32B2274/00 , B32B2307/304 , B32B2307/54 , B32B2307/718 , B32B2307/7242 , B32B2307/7265 , B32B2439/60 , B32B2439/70 , B65D1/0215 , F16L11/04 , F16L55/1152 , F16L55/1157 , F16L2011/047 , Y10T428/1352 , Y10T428/1379 , Y10T428/1383 , Y10T428/1393 , Y10T428/249971 , Y10T428/31504 , Y10T428/31786 , Y10T428/31938
摘要： An extruded blow molded bottle comprises a neck portion and a body portion. The body portion comprises a first inner layer and a second layer. The first inner layer comprises a first material selected from a group consisting of polyester, phenoxy type thermoplastics, phenoxy-polyolefin thermoplastic blends, and combinations thereof. The second layer comprises a second material selected from a group consisting of virgin PET, recycled PET, PETG, foam, polypropylene, polyester, polyolefins, phenoxy type thermoplastic, phenoxy-polyolefin thermoplastic blends, regrind scrap materials, and combinations thereof. The second material is different from the first material.
摘要翻译：挤出的吹塑瓶包括颈部和主体部分。主体部分包括第一内层和第二层。第一内层包括选自聚酯，苯氧基型热塑性塑料，苯氧基 - 聚烯烃热塑性共混物及其组合的第一种材料。第二层包括选自原始PET，再循环PET，PETG，泡沫，聚丙烯，聚酯，聚烯烃，苯氧基型热塑性塑料，苯氧基 - 聚烯烃热塑性共混物，再研磨废料及其组合的第二材料。第二种材料与第一种材料不同。

3. 发明申请

WO2005102667A3 PREFORMS, BOTTLES AND METHODS OF MANUFACTURING THE PREFORMS AND THE BOTTLES 审中-公开
标题翻译：预制品，瓶子和制造预制品和瓶子的方法
公开(公告)号：WO2005102667A3
公开(公告)日：2006-03-09
申请号：PCT/US2005013078
申请日：2005-04-18
申请人： ADVANCED PLASTICS TECHNOLOGIES , HUTCHINSON GERALD , LEE ROBERT , FARHA SAID
发明人： HUTCHINSON GERALD , LEE ROBERT , FARHA SAID
IPC分类号： B29C45/16 , B29C49/04 , B29C49/06 , B29C49/22 , B65D1/02 , B65D23/08 , B67D1/00 , B29C37/00
CPC分类号： B29C49/22 , B29B2911/1402 , B29B2911/14026 , B29B2911/1404 , B29B2911/14053 , B29B2911/1406 , B29B2911/14066 , B29B2911/1408 , B29B2911/14093 , B29B2911/14106 , B29B2911/14113 , B29B2911/1412 , B29B2911/14126 , B29B2911/1424 , B29B2911/14246 , B29B2911/14253 , B29B2911/1426 , B29B2911/14266 , B29B2911/14273 , B29B2911/1428 , B29B2911/14646 , B29C44/04 , B29C45/1684 , B29C49/04 , B29C49/06 , B29C49/12 , B29C49/221 , B29C51/10 , B29C70/603 , B29C70/66 , B29C2049/0089 , B29C2049/225 , B29C2791/006 , B29K2023/083 , B29K2023/086 , B29K2023/12 , B29K2067/00 , B29K2105/0076 , B29K2105/04 , B29K2105/048 , B29K2105/162 , B29K2105/165 , B29K2105/253 , B29K2105/258 , B29K2105/26 , B29K2623/12 , B29K2995/0015 , B29K2995/0067 , B29L2009/00 , B29L2023/22 , B29L2031/463 , B29L2031/7158 , B29L2031/716 , B32B1/02 , B32B5/18 , B32B5/20 , B32B27/065 , B32B27/08 , B32B27/32 , B32B27/325 , B32B27/36 , B32B2266/025 , B32B2266/0264 , B32B2274/00 , B32B2307/304 , B32B2307/54 , B32B2307/718 , B32B2307/7242 , B32B2307/7265 , B32B2439/60 , B32B2439/70 , B65D1/0215 , F16L11/04 , F16L55/1152 , F16L55/1157 , F16L2011/047 , Y10T428/1352 , Y10T428/1379 , Y10T428/1383 , Y10T428/1393 , Y10T428/249971 , Y10T428/31504 , Y10T428/31786 , Y10T428/31938
摘要： A preform comprising a neck portion and a body portion having a wall portion an end cap, the body portion comprising a first layer and a second layer, the second layer, the second layer comprising an expandable material; a preform comprising a threaded neck portion and a body portion including a wall portio: and an end cap, the body portion comprising expandable material adapted to produce foam when activated; methods of forming the preforms; the bottles manufactured and methods of injection moulding using multiple gates, outlets, exhaust systems or mould cavities.
摘要翻译：一种预成型件，其包括颈部和主体部分，所述主体部分具有壁部分和端盖，所述主体部分包括第一层和第二层，所述第二层，所述第二层包括可膨胀材料; 包括螺纹颈部和包括壁口的主体部分的预成型件和端盖，所述主体部分包括适于在被激活时产生泡沫的可膨胀材料; 形成预成型件的方法; 制造的瓶子和使用多个浇口，出口，排气系统或模腔的注射成型方法。

4. 发明申请

WO2014004816A3 DRY CLEANING MACHINE WITH A REFRIGERATION SYSTEM ADOPTED FOR MULTIPLE SOLVENTS 审中-公开
标题翻译：具有用于多种溶剂的制冷系统的干式清洁机
公开(公告)号：WO2014004816A3
公开(公告)日：2014-05-01
申请号：PCT/US2013048161
申请日：2013-06-27
申请人： LEE ROBERT
发明人： LEE ROBERT
IPC分类号： D06F43/02 , D06F43/08
CPC分类号： D06F43/02 , D06F43/088
摘要： A dry cleaning machine with washing and drying cycles and a refrigeration system has a rotary drum (300) holding clothing or likes, a first solvent tank (601) for storing a first solvent for a first washing cycle, a second solvent tank (602) storing a second solvent for a second washing cycle, a first water separator (401) operationally connected to the first solvent tank (601), a second water separator (402) operationally connected to the second solvent tank (602), and a solvent recovery system (100) operationally connected to the first and second water separators at one end and the rotary drum. The refrigeration system contains a first heat exchange system (4), a second heat exchange system (3), a refrigeration tank (1) storing a refrigerant, and a fan (9) for cooling the refrigerant. The dry cleaning machine is configured so that the different solvents can be independently used within the same machine for different washing cycles without need of manual exchange of the solvents or system purge.
摘要翻译：具有洗涤和干燥循环的干洗机和制冷系统具有保持衣物的旋转滚筒（300），用于储存用于第一洗涤循环的第一溶剂的第一溶剂罐（601），第二溶剂罐（602）存储用于第二洗涤循环的第二溶剂，与第一溶剂罐（601）可操作地连接的第一水分离器（401），可操作地连接到第二溶剂罐（602）的第二水分离器（402）和溶剂回收系统（100）在一端可操作地连接到第一和第二水分离器以及旋转滚筒。制冷系统包括第一热交换系统（4），第二热交换系统（3），存储制冷剂的冷藏箱（1）和用于冷却制冷剂的风扇（9）。干洗机的配置使得不同的溶剂可以在同一机器内独立使用，用于不同的洗涤循环，无需手动更换溶剂或系统清洗。

5. 发明申请

WO2012065060A2 GAS-FILLED MICROBUBBLES AND SYSTEMS FOR GAS DELIVERY 审中-公开
标题翻译：用于气体输送的气体填充微生物和系统
公开(公告)号：WO2012065060A2
公开(公告)日：2012-05-18
申请号：PCT/US2011060368
申请日：2011-11-11
申请人： CHILDRENS MEDICAL CENTER , KHEIR JOHN , MCGOWAN FRANCIS X , LOXLEY ANDREW , LEE ROBERT
发明人： KHEIR JOHN , MCGOWAN FRANCIS X , LOXLEY ANDREW , LEE ROBERT
IPC分类号： A61K47/48 , A61K9/127 , A61K9/24 , A61K9/46 , A61K47/30
CPC分类号： A61K9/5015 , A01N1/021 , A61B5/029 , A61K9/0019 , A61K9/10 , A61K9/127 , A61K33/00 , A61K47/10 , A61M5/19 , A61M16/00
摘要： Compressible and concentrated suspensions containing gas-filled microbubbles, uses thereof for delivering gas into a subject in need thereof, and systems for delivering the compressible suspensions. The gas-filled microbubbles each comprise a gas core surrounded by a lipid membrane, which includes (a) one or more lipids, such as 1,2-disteroyl-sn-glycero- 3-phosphocholine (DSPC) or dipalmitoylphosphatidylcholine (DPPC), and (b) one or more stabilizing detergents, such as poloxamer 188, Pluronic F108, Pluronic F127, polyoxyethylene (100) stearyl ether, cholesterol, gelatin, polyvinylpyrrolidone (PVP), and sodium deoxycholate (NaDoc).
摘要翻译：含有充气微泡的可压缩和浓缩悬浮液，其用于将气体输送到有需要的受试者中，以及用于递送可压缩悬浮液的系统。充气微泡各自包含由脂质膜包围的气芯，其包括（a）一种或多种脂质，例如1,2-二甲酰基-sn-甘油-3-磷酸胆碱（DSPC）或二棕榈酰磷脂酰胆碱（DPPC），和（b）一种或多种稳定洗涤剂，如泊洛沙姆188，Pluronic F108，Pluronic F127，聚氧乙烯（100）硬脂醚，胆固醇，明胶，聚乙烯吡咯烷酮（PVP）和脱氧胆酸钠（NaDoc）。

6. 发明申请

WO0009096B1 INJECTABLE FORMULATIONS OF NANOPARTICULATE NAPROXEN 审中-公开
标题翻译：纳米粒子纳豆酮的注射剂配方
公开(公告)号：WO0009096B1
公开(公告)日：2000-03-30
申请号：PCT/US9918270
申请日：1999-08-12
申请人： NANOSYSTEMS , LEE ROBERT , CASTRO LAN DE
发明人： LEE ROBERT , DE CASTRO LAN
IPC分类号： A61K9/51 , A61K9/14 , A61K31/192 , A61K47/32 , A61P19/02 , A61P19/06 , A61P29/00 , A61K9/10
CPC分类号： A61K9/146 , A61K31/192 , Y10S977/773 , Y10S977/779 , Y10S977/906 , Y10S977/908 , Y10T428/2985
摘要： Described are an injectable formulation of nanoparticulate naproxen that produces minimal or no pain or burning sensation upon administration, and methods of making and using such a formulation. The injectable formulation comprises nanoparticulate naproxen having a povidone polymer adsorbed on the surface thereof in an amount sufficient to maintain an effective average particle size of less than about 600 nm.
摘要翻译：描述的是纳米颗粒萘普生的可注射制剂，其在施用时产生最少或没有疼痛或灼烧感，以及制备和使用这种制剂的方法。可注射制剂包含具有吸收在其表面上的聚维酮聚合物的纳米颗粒萘普生，其量足以保持有效平均粒度小于约600nm。

7. 发明申请

WO2009033131A3 MULTI-PHASIC, NANO-STRUCTURED COMPOSITIONS CONTAINING A COMBINATION OF A FIBRATE AND A STATIN 审中-公开
标题翻译：含有一种纤维素和一种抗坏血酸的组合的多相纳米结构组合物
公开(公告)号：WO2009033131A3
公开(公告)日：2009-12-30
申请号：PCT/US2008075544
申请日：2008-09-08
申请人： NOVAVAX INC , SHENOY DINESH , LEE ROBERT
发明人： SHENOY DINESH , LEE ROBERT
IPC分类号： A61K9/00
CPC分类号： A61K9/107 , A61K9/0056 , A61K9/0095 , A61K9/10 , A61K9/4866 , A61K31/00 , A61K31/401 , A61K45/06 , A61K47/10 , A61K47/14 , A61K47/26 , A61K47/38 , A61K2300/00
摘要： The present invention discloses a pharmaceutical formulation containing a multi-phasic pharmaceutical composition in an oral dosage form. The multi-phasic pharmaceutical composition contains: (a) a fibrate, or a pharmaceutically acceptable salt, ester, hydrate, or prodrug thereof; (b) a statin, or a pharmaceutically acceptable salt, ester, hydrate, or prodrug thereof; (c) a solvent; (d) a non-miscible liquid; (e) a stabilizer; and (f) water. The fibrate or the statin or both is in a particulate state and/or a solubilized state. Such pharmaceutical formulations are capable of reducing the fed/fast variability and improving oral bioavailability to which a number of active pharmaceutical ingredients are susceptible. The pharmaceutical formulations of the invention, therefore are bioequivalent in fed and fasted states and have improved oral bioavailability.
摘要翻译：本发明公开了含有口服剂型的多相药物组合物的药物制剂。多相药物组合物含有：（a）贝特类或其药学上可接受的盐，酯，水合物或前药; （b）他汀或其药学上可接受的盐，酯，水合物或前药; （c）溶剂; （d）不混溶液体; （e）稳定剂; 和（f）水。贝特类药物或他汀类药物或二者均处于颗粒状态和/或溶解状态。这样的药物制剂能够降低喂食/快速变异性并改善许多活性药物成分易感的口服生物利用度。因此，本发明的药物制剂在进食和禁食状态下是生物等效的并具有改善的口服生物利用度。

8. 发明申请

WO2009023771A3 SEQUENCING AND REPRODUCING SETS OF TEXT AND GRAPHICS ACROSS A COLLECTION OF PRINTABLE AREAS 审中-公开
标题翻译：通过收集可打印区域的文本和图形的顺序和复制集
公开(公告)号：WO2009023771A3
公开(公告)日：2009-06-04
申请号：PCT/US2008073147
申请日：2008-08-14
申请人： AVERY DENNISON CORP , LEE ROBERT , MCGEE PHILLIP , LLOYD DON
发明人： LEE ROBERT , MCGEE PHILLIP , LLOYD DON
IPC分类号： B42F21/00
CPC分类号： G06F17/211 , B42F21/02 , G09F2003/023
摘要： A method of sequencing and reproducing sets of text and graphics across a collection of printable areas and a computer readable medium having computer-executable instructions for performing the method. The method providing the user the ability to select many variables for the printing of labels for tabs. The method and computer readable medium providing for the creation of divider insert tab labels (106) for the tabs (104) of a set of divider inserts (102) thereby identifying the divided contents. The method and computer printable medium provide for printing of the divider insert tab labels in an order that they are assembled into a binder (100).
摘要翻译：一种在可打印区域的集合上排序和再现文本和图形集合的方法以及具有用于执行该方法的计算机可执行指令的计算机可读介质。该方法为用户提供了为标签打印标签选择许多变量的能力。该方法和计算机可读介质提供用于为一组分隔器插入件（102）的突片（104）创建分隔器插入片标签（106），从而识别分割的内容物。该方法和计算机可打印介质以按组装到粘合剂（100）中的顺序提供打印分隔件插入片标签。

9. 发明申请

WO2007103294A2 NANO-STRUCTURED COMPOSITIONS AND METHODS OF MAKING AND USING THE SAME 审中-公开
标题翻译：纳米结构组合物及其制备和使用方法
公开(公告)号：WO2007103294A2
公开(公告)日：2007-09-13
申请号：PCT/US2007005562
申请日：2007-03-06
申请人： NOVAVAX INC , LEE ROBERT , SHENOY DINESH , WRIGHT D CRAIG
发明人： LEE ROBERT , SHENOY DINESH , WRIGHT D CRAIG
IPC分类号： A61K9/107
CPC分类号： A61K9/1075
摘要： The present invention provides a new tri-phasic method for making nanoparticles of poorly soluble active pharmaceutical ingredients
摘要翻译：本发明提供了用于制备难溶性活性药物成分的纳米颗粒的新三相方法

10. 发明申请

WO2007034194A3 A PRINTER 审中-公开
标题翻译：打印机
公开(公告)号：WO2007034194A3
公开(公告)日：2007-07-26
申请号：PCT/GB2006003520
申请日：2006-09-21
申请人： FOCUS LABEL MACHINERY LTD , LEE BRIAN , WHITE DANIEL , LEE DAVID , BEARDSLEY MARTIN , LEE PHILIP , LEE ROBERT
发明人： LEE BRIAN , WHITE DANIEL , LEE DAVID , BEARDSLEY MARTIN , LEE PHILIP , LEE ROBERT
IPC分类号： B41F31/30 , B41F13/004
CPC分类号： B41F13/0045 , B41F31/307
摘要： A printer comprising: a central drum (4) having a first side and an opposite second side, and rotatable about a central axis (6) , and a print cylinder (8) having a first side and an opposite second side and rotatable about a second axis spaced apart from and substantially parallel to the central axis (6), characterised in that the printer (2) further comprises a print cylinder adjuster (32) for adjusting the distance between the second axis and the central axis (6).
摘要翻译：一种打印机，包括：中心鼓（4），其具有第一侧和相对的第二侧，并且可围绕中心轴线（6）旋转;以及打印滚筒（8），其具有第一侧和相对的第二侧，第二轴线与中心轴线（6）间隔开并且基本上平行于中心轴线（6），其特征在于，所述打印机（2）还包括用于调节所述第二轴线和所述中心轴线（6）之间的距离的打印滚筒调节器（32）。

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