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1. 发明申请

WO2009029866A3 MINIMIZING TRAUMA DURING AND AFTER INSERTION OF A COCHLEAR LEAD 审中-公开
标题翻译：在引进领导之前和之后最小化TRAUMA
公开(公告)号：WO2009029866A3
公开(公告)日：2009-05-07
申请号：PCT/US2008074890
申请日：2008-08-29
申请人： ADVANCED BIONICS LLC , OVERSTREET EDWARD H , FALTYS MICHAEL A , XIE JIAN , COLVIN MICHAEL S
发明人： OVERSTREET EDWARD H , FALTYS MICHAEL A , XIE JIAN , COLVIN MICHAEL S
IPC分类号： A61N1/05 , A61F11/00 , A61K9/00
CPC分类号： A61N1/0541 , A61K9/0024 , A61K9/0046 , A61K31/495
摘要： A method for delivering dexamethasone base (DXMb) via an implantable electrode (195, 1200, 1400, 1500, 1600) includes coupling DXMb to the implantable electrode (195, 1200, 1400, 1500, 1600) and inserting the implantable electrode (195, 1200, 1400, 1500, 1600) into animal tissue (150), the DXMb eluting into the animal tissue (150). An implantable nerve stimulating device (100, 1200, 1400, 1500, 1600) includes an elongated member (195) having a distal end bearing at least one electrode; and DXMb coupled to the elongated member (195), the DXMb being eluted into tissue (150) surrounding the elongated member (195).
摘要翻译：通过可植入电极（195,12400,1400,1600）递送地塞米松碱（DXMb）的方法包括将DXMb连接到可植入电极（195,1200,1400,1500,1600）并将可植入电极（195， 1200,1400,1600）转移到动物组织（150）中，DXMb洗脱到动物组织（150）中。植入式神经刺激装置（100,1200,1400,1500,1600）包括细长构件（195），其具有至少一个电极的远端; 和耦合到细长构件（195）的DXMb，DXMb被洗脱到围绕细长构件（195）的组织（150）中。

2. 发明申请

WO2012154865A2 SINGLE-PULSE ACTIVATION OF THE CHOLINERGIC ANTI-INFLAMMATORY PATHWAY TO TREAT CHRONIC INFLAMMATION 审中-公开
标题翻译：单因素激光治疗慢性淋巴细胞白血病抗炎炎症途径的单脉冲激活
公开(公告)号：WO2012154865A2
公开(公告)日：2012-11-15
申请号：PCT/US2012037142
申请日：2012-05-09
申请人： SETPOINT MEDICAL CORP , LEVINE JACOB A , FALTYS MICHAEL A
发明人： LEVINE JACOB A , FALTYS MICHAEL A
IPC分类号： A61N1/36 , A61N1/05 , A61N1/372
CPC分类号： A61N1/36053 , A61N1/3606 , F04C2270/0421
摘要： Described herein are methods and systems for applying extremely low duty-cycle stimulation sufficient to treat chronic inflammation. In particular, described herein are single supra-threshold pulses of electrical stimulation sufficient to result in a long-lasting (e.g., >4 hours, greater than 12 hours, greater than 24 hours, greater than 48 hours) inhibition of pro-inflammatory cytokines and/or effects of chronic inflammation. These methods and devices are particularly of interest in treatment of inflammatory bowel disease (IBD).
摘要翻译：本文描述的是应用极低的占空比刺激足以治疗慢性炎症的方法和系统。特别地，本文描述的是电刺激的单一超阈值脉冲，其足以导致促炎细胞因子的持久（例如> 4小时，大于12小时，大于24小时，大于48小时）的抑制和/或慢性炎症的作用。这些方法和装置在治疗炎症性肠病（IBD）中特别有意义。

3. 发明申请

WO2011028763A3 PRESCRIPTION PAD FOR TREATMENT OF INFLAMMATORY DISORDERS 审中-公开
标题翻译：用于治疗炎性疾病的处方垫
公开(公告)号：WO2011028763A3
公开(公告)日：2011-07-14
申请号：PCT/US2010047464
申请日：2010-09-01
申请人： SETPOINT MEDICAL CORP , ZITNIK RALPH J , FALTYS MICHAEL A
发明人： ZITNIK RALPH J , FALTYS MICHAEL A
IPC分类号： A61N1/372 , A61B5/0402 , A61B5/0488 , A61B5/055 , A61N1/36
CPC分类号： A61N1/08 , A61N1/372 , A61N1/37247
摘要： Described herein are devices, including interface modules or prescription pads, and systems including these devices and methods of using them, for treating inflammation or inflammatory disorders, and particularly for interfacing with a user desiring to prescribe treatment of an inflammatory disorder using an implanted stimulator.
摘要翻译：本文描述了包括界面模块或处方垫的装置，以及包括这些装置的系统和使用它们的方法，用于治疗炎症或炎性病症，并且特别用于与希望使用植入的刺激器开处理炎性病症的用户进行接口。

4. 发明申请

WO2010144578A3 NERVE CUFF WITH POCKET FOR LEADLESS STIMULATOR 审中-公开
标题翻译： NERVE CUFF带有无铅刺激器的口袋
公开(公告)号：WO2010144578A3
公开(公告)日：2011-03-31
申请号：PCT/US2010037975
申请日：2010-06-09
申请人： SETPOINT MEDICAL CORP , FALTYS MICHAEL A , MARTIN ROY , SCOTT STEVEN E , LOEB GERALD
发明人： FALTYS MICHAEL A , MARTIN ROY , SCOTT STEVEN E , LOEB GERALD
IPC分类号： A61N1/36 , A61N1/05
CPC分类号： A61N1/0556 , A61N1/0558 , A61N1/36114 , A61N1/37205 , A61N1/375 , A61N1/3756
摘要： An extravascular nerve cuff that is configured to hold a leadless, integral, implantable microstimulator. The nerve cuff may include a cuff body having a pocket or pouch for removably receiving the implantable device within. The nerve cuff can be secured around the nerve such that the electrodes of the device are stably positioned relative to the nerve. Furthermore, the nerve cuff drives the majority of the current from the stimulation device into the nerve, while shielding surrounding tissues from unwanted stimulation.
摘要翻译：构造成保持无引导，整体的可植入微型刺激器的血管外神经袖带。神经箍可以包括具有袋或袋的袖带体，用于在其内可移除地接收可植入装置。神经袖口可以固定在神经周围，使得装置的电极相对于神经被稳定地定位。此外，神经套囊将大部分电流从刺激装置驱动到神经中，同时屏蔽周围组织免受不必要的刺激。

5. 发明申请

WO2011079309A3 NEURAL STIMULATION DEVICES AND SYSTEMS FOR TREATMENT OF CHRONIC INFLAMMATION 审中-公开
标题翻译：神经刺激装置和治疗慢性炎症的系统
公开(公告)号：WO2011079309A3
公开(公告)日：2011-11-24
申请号：PCT/US2010062082
申请日：2010-12-23
申请人： SETPOINT MEDICAL CORP , FALTYS MICHAEL A , SIMON JESSE M , LIU YIMING
发明人： FALTYS MICHAEL A , SIMON JESSE M , LIU YIMING
IPC分类号： A61N1/372 , A61N1/05 , A61N1/36
CPC分类号： A61N1/3787 , A61N1/0556 , A61N1/36053 , A61N1/3606 , A61N1/36125 , A61N1/36142 , A61N1/36175 , A61N1/37205 , A61N1/37235 , A61N1/375 , A61N1/3756
摘要： A system for treating chronic inflammation may include an implantable microstimulator, a wearable charger, and optionally an external controller. The implantable microstimulator may be implemented as a leadless neurostimulator implantable in communication with a cervical region of a vagus nerve. The microstimulator can address several types of stimulation including regular dose delivery. The wearable charger may be worn around the subject's neck to rapidly (
摘要翻译：用于治疗慢性炎症的系统可以包括可植入微型刺激器，可穿戴充电器和任选的外部控制器。可植入微刺激器可以被实现为可植入与迷走神经的子宫颈区域连通的无引导神经刺激器。微型刺激器可以解决几种类型的刺激，包括定期给药。穿戴式充电器可能会在受试者颈部周围快速穿戴（每周<10分钟），对植入的微型刺激器进行充电。外部控制器可以被配置为控制微型激励器的剂量和活性的处方垫。

6. 发明申请

WO03030772A2 A MICROPHONE MODULE FOR USE WITH A HEARING AID OR COCHLEAR IMPLANT SYSTEM 审中-公开
标题翻译：麦克风模块用于听力助听器或COCHLEAR植入系统
公开(公告)号：WO03030772A2
公开(公告)日：2003-04-17
申请号：PCT/US0231837
申请日：2002-10-03
申请人： ADVANCED BIONICS CORP , MALTAN ALBERT A , FALTYS MICHAEL A , KUZMA JANUSZ A
发明人： MALTAN ALBERT A , FALTYS MICHAEL A , KUZMA JANUSZ A
IPC分类号： H04R1/08 , H04R25/00 , A61F
CPC分类号： H04R25/604 , A61N1/36036 , H04R25/554 , H04R2225/021 , H04R2225/67
摘要： A microphone module (60) is shaped for insertion into a tunnel (40) made through the soft tissue that connects the retro-auricular space (50) with the ear canal (30). A hollow tube (44) may first be chronically or acutely implanted in such tunnel, and the microphone module inserted into the tube. The microphone module contains a microphone (63) located on the distal part (68) of the module close to or inside the ear canal. In some embodiments, a battery or other power source (66) that powers the module, and signal processing circuitry (67) may also be included in the module. In yet other embodiments, the module may include telemetry circuitry (64, 69). In some embodiments, a behind-the-ear (BTE) speech processor connects to a proximal end of the microphone module. Electrical signals produced by the microphone in response to sensed sound waves may be processed, if needed, by the signal processing circuitry, and provided (via telemetry or physical connections) to the BTE speech processor, or other external or implanted hearing aid component, for use by a hearing system (79), e.g., a cochlear implant system, of which the component is a part. The hearing system may be an external, partially implanted, or fully implanted hearing system, such as a cochlear implant system.
摘要翻译：麦克风模块（60）被成形为用于插入通过软管组织制成的隧道（40），所述软组织将回耳孔（50）与耳道（30）连接。中空管（44）可以首先在这种隧道中长期或急性地植入，并且将麦克风模块插入管中。麦克风模块包括位于模块的远端部分（68）上的麦克风（63），靠近或在耳道内。在一些实施例中，为模块供电的电池或其他电源（66）以及信号处理电路（67）也可以包括在模块中。在其他实施例中，模块可以包括遥测电路（64,69）。在一些实施例中，耳后（BTE）语音处理器连接到麦克风模块的近端。由麦克风响应于感测到的声波产生的电信号可以由信号处理电路进行处理，并通过遥测或物理连接提供给BTE语音处理器或其它外部或植入式助听器组件，用于由听力系统（79）使用，例如耳蜗植入系统，其中组件是其中的一部分。听力系统可以是外部的，部分植入的或完全植入的听觉系统，例如人工耳蜗植入系统。

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